Federico Soria
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soriafn.bsky.social
Federico Soria
@soriafn.bsky.social
Neurobiologist at Achucarro Basque Center for Neuroscience (GlioMatrixLab). Investigating the extracellular matrix in healthy and diseased brain 🔬🧠. Also on X (@SoriaFN)
Pinned
We are happy to present AAV-Ncan-GFP, a genetically-encoded fluorescent probe for live #imaging of the extracellular matrix in the mouse brain.

Stay tuned for the peer-reviewed version, with more insights on live #ECM monitoring by two-photon microscopy!

www.biorxiv.org/content/10.1...
Viral-mediated fluorescent labeling of hyaluronan reveals extracellular matrix dynamics in the mouse brain in vivo
The extracellular matrix (ECM) of the brain is primarily composed of the glycan polymer hyaluronan (HA), a core scaffold that nucleates proteoglycans forming a self-assembled matrix that acts as struc...
www.biorxiv.org
Want to tag the #ECM for live imaging?

Our AAV vector, pAAV-CMVie-NcanGFP (a genetically encoded fluorescent tag for hyaluronan) is now available at Addgene!

addgene.org/235983/
June 19, 2025 at 10:34 AM
This was science fiction not long ago. Now it's a reality:
Brain-computer interface decodes language and reproduces it with nuances (tone, etc). I wonder how long until they can decode thoughts and show them as images/videos.

Black Mirror stuff!

www.nature.com/articles/d41...
World first: brain implant lets man speak with expression — and sing
Device translates thought to speech in real time.
www.nature.com
June 18, 2025 at 9:45 AM
Reposted by Federico Soria
📢 New webinar coming soon 📢 
Clare Pridans from Institute for Regeneration and Repair, University of Edinburgh will be our next speaker on June 3rd. Check all the information in the flyer and add it to your calendar! 🧠👩🏻‍🔬
May 27, 2025 at 11:27 AM
Happy to be part of this beautiful work from Maria Domercq and Alejandro Montilla.
The paper explores the role of microglia in myelin clearance after demyelination, and how lipid accumulation in mice without IRF5 (immune response-related) impairs remyelination.
link.springer.com/article/10.1...
Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5 - Cellular and Molecular Life Sciences
Interferon regulatory factor 5 (IRF5) is a transcription factor that plays a role in orchestrating innate immune responses, particularly in response to viral infections. Notably, IRF5 has been identif...
link.springer.com
April 8, 2025 at 1:59 PM
Super interesting symposium and great discussion at #NWG2025.

Thanks Egor and Alexander and Constanze for the invitation and the delicious lunch under the spring sun of Göttingen.
March 28, 2025 at 6:52 PM
Ready for some Extracellular Matrix science at Göttingen, within the German Neuroscience Society meeting. #NWG2025
March 27, 2025 at 10:53 AM
This is next Tuesday!
📢New webinar coming soon📢 
Prof. Steffen Jung from Weizmann Institute of Science will be our next speaker on April 1st. Check all the information in the flyer and add it to your calendar! 🧠🔬
March 25, 2025 at 9:01 AM
"What if you could listen to music without headphones and without disturbing anyone around you?"
Audible enclaves... localized pockets of sound that are isolated from their surroundings.
Los auriculares del futuro...
theconversation.com/researchers-...
Researchers created sound that can bend itself through space, reaching only your ear in a crowd
By combining ultrasound with a concept called nonlinear acoustics, you can create sound that stays silent until it reaches a specific location.
theconversation.com
March 19, 2025 at 8:59 AM
Reposted by Federico Soria
NcanGFP in live brain tissue
February 6, 2025 at 9:22 AM
We are happy to present AAV-Ncan-GFP, a genetically-encoded fluorescent probe for live #imaging of the extracellular matrix in the mouse brain.

Stay tuned for the peer-reviewed version, with more insights on live #ECM monitoring by two-photon microscopy!

www.biorxiv.org/content/10.1...
Viral-mediated fluorescent labeling of hyaluronan reveals extracellular matrix dynamics in the mouse brain in vivo
The extracellular matrix (ECM) of the brain is primarily composed of the glycan polymer hyaluronan (HA), a core scaffold that nucleates proteoglycans forming a self-assembled matrix that acts as struc...
www.biorxiv.org
February 6, 2025 at 9:20 AM
This is today. No recording, so it won't be available in our website.
Don't miss it!
📢New webinar coming soon📢 
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
February 4, 2025 at 11:59 AM
Next Tuesday!
📢New webinar coming soon📢 
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
January 28, 2025 at 6:03 PM
Reposted by Federico Soria
📢New webinar coming soon📢 
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
January 28, 2025 at 10:48 AM
Great opportunity!
We launched an open call to select a new Scientific Director for ACHUCARRO.

All the details of the call, here:
www.achucarro.org/job/scientif...
January 21, 2025 at 9:50 PM
Hola Bluesky científico. Soy totalmente nuevo aquí.

Como funciona? (Hashtags, menciones, todo eso es igual?)

Cual es la principal diferencia con la red social innombrable?

Gracias 🙂
January 21, 2025 at 9:46 PM