Anna Kalisvaart
@akalisva.bsky.social
Instructor in Neuroscience @BurkeNeuroSci & @WeillCornell
Translational stroke researcher (Intracerebral Hemorrhage) | PhD @UAlberta 🇨🇦 | Microscopy, cycling, & linocut geek. Views are my own.
Translational stroke researcher (Intracerebral Hemorrhage) | PhD @UAlberta 🇨🇦 | Microscopy, cycling, & linocut geek. Views are my own.
Pinned
Anna Kalisvaart
@akalisva.bsky.social
· Nov 20
The sky really is blue here!
By way of introduction, my name is Anna, I’m a translational #stroke researcher interested in all things cell bio 🧪 I’m also passionate about writing, making #SciArt linocut prints, noodles (in any format), my animals, and cycling. Hello!
#neuroscience #neuroskyence
By way of introduction, my name is Anna, I’m a translational #stroke researcher interested in all things cell bio 🧪 I’m also passionate about writing, making #SciArt linocut prints, noodles (in any format), my animals, and cycling. Hello!
#neuroscience #neuroskyence
Reposted by Anna Kalisvaart
Thank you for coming to my TED Talk 🎤
If you’ve read this far and still need convincing, please check out our preprint arxiv.org/abs/2511.04820 and this infographic: doi.org/10.5281/zeno...
10/10
If you’ve read this far and still need convincing, please check out our preprint arxiv.org/abs/2511.04820 and this infographic: doi.org/10.5281/zeno...
10/10
November 13, 2025 at 8:17 PM
Thank you for coming to my TED Talk 🎤
If you’ve read this far and still need convincing, please check out our preprint arxiv.org/abs/2511.04820 and this infographic: doi.org/10.5281/zeno...
10/10
If you’ve read this far and still need convincing, please check out our preprint arxiv.org/abs/2511.04820 and this infographic: doi.org/10.5281/zeno...
10/10
As I worked on this #sciart piece this weekend, it got me curious about the origin of the mouse strains we use in biomedical research today: so welcome to my rabbit hole! A 🧵
November 9, 2025 at 7:02 PM
As I worked on this #sciart piece this weekend, it got me curious about the origin of the mouse strains we use in biomedical research today: so welcome to my rabbit hole! A 🧵
Reposted by Anna Kalisvaart
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 19/31
Prompt ARCTIC
Pdb: 3UYU
Meet ice-binding protein (LeIBP) from Arctic yeast that acts like antifreeze!
Next: RIVALS
Suggestions?
Day 19/31
Prompt ARCTIC
Pdb: 3UYU
Meet ice-binding protein (LeIBP) from Arctic yeast that acts like antifreeze!
Next: RIVALS
Suggestions?
October 21, 2025 at 2:41 AM
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 19/31
Prompt ARCTIC
Pdb: 3UYU
Meet ice-binding protein (LeIBP) from Arctic yeast that acts like antifreeze!
Next: RIVALS
Suggestions?
Day 19/31
Prompt ARCTIC
Pdb: 3UYU
Meet ice-binding protein (LeIBP) from Arctic yeast that acts like antifreeze!
Next: RIVALS
Suggestions?
Reposted by Anna Kalisvaart
Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling
Stroke is a major cause of disability. Astrocytes respond to stroke in a gradated manner, but details of that response and its consequences for tissue…
www.sciencedirect.com
October 10, 2025 at 11:13 PM
Thrilled to share this work from my postdoc with Tom Carmichael, available online @ Neuron! Long story short: we find even more evidence that all reactive astrocytes are not equal, and we can take advantage of those differences to improve repair after stroke.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Anna Kalisvaart
Reposted by Anna Kalisvaart
Paper Alert!! Our collaborative work with Giger Lab at UMich is out now in #ScienceTranslationMedicine Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury | Science Translational Medicine @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury
In Sarm1-deficient mice, peripheral nervous system regeneration is delayed after injury.
www.science.org
October 8, 2025 at 6:22 PM
Paper Alert!! Our collaborative work with Giger Lab at UMich is out now in #ScienceTranslationMedicine Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury | Science Translational Medicine @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Anna Kalisvaart
🧪🥤Researchers find Canada’s first sugary drink tax lowered odds of consumption nearly 25%
New report highlights the potential of the tax to improve public health
@avisfavaro.bsky.social
www.heartandstroke.ca/what-we-do/m...
New report highlights the potential of the tax to improve public health
@avisfavaro.bsky.social
www.heartandstroke.ca/what-we-do/m...
Pouring over the data: researchers find Canada’s first sugary drink tax lowered odds of consumption nearly 25%
www.heartandstroke.ca
October 1, 2025 at 10:02 PM
🧪🥤Researchers find Canada’s first sugary drink tax lowered odds of consumption nearly 25%
New report highlights the potential of the tax to improve public health
@avisfavaro.bsky.social
www.heartandstroke.ca/what-we-do/m...
New report highlights the potential of the tax to improve public health
@avisfavaro.bsky.social
www.heartandstroke.ca/what-we-do/m...
Reposted by Anna Kalisvaart
Very sorry to hear of Jane Goodall’s passing. Her scientific contributions and her work as a conservationist are extraordinary.
#goodall #chimpanzee #conservation #primatology
🧪
Gift article
#goodall #chimpanzee #conservation #primatology
🧪
Gift article
Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91
www.nytimes.com
October 1, 2025 at 7:52 PM
Very sorry to hear of Jane Goodall’s passing. Her scientific contributions and her work as a conservationist are extraordinary.
#goodall #chimpanzee #conservation #primatology
🧪
Gift article
#goodall #chimpanzee #conservation #primatology
🧪
Gift article
Reposted by Anna Kalisvaart
Occasional PSA:
Intracellular molecular processing, especially in neurons, is not about differential RNA expression or even protein abundance for that matter. Not about quantity.
It’s about qualitative, functional states.
The sooner we get there as a community the faster the science advances
Intracellular molecular processing, especially in neurons, is not about differential RNA expression or even protein abundance for that matter. Not about quantity.
It’s about qualitative, functional states.
The sooner we get there as a community the faster the science advances
September 30, 2025 at 1:35 AM
Occasional PSA:
Intracellular molecular processing, especially in neurons, is not about differential RNA expression or even protein abundance for that matter. Not about quantity.
It’s about qualitative, functional states.
The sooner we get there as a community the faster the science advances
Intracellular molecular processing, especially in neurons, is not about differential RNA expression or even protein abundance for that matter. Not about quantity.
It’s about qualitative, functional states.
The sooner we get there as a community the faster the science advances
10/10 use of Lego bricks!
Mäntylä, E., & Ihalainen, T. O. (2021). Brick Strex: a robust device built of LEGO bricks for mechanical manipulation of cells. Scientific Reports, #EpithelialMechanics www.nature.com/articles/s41...
September 17, 2025 at 6:53 AM
10/10 use of Lego bricks!
Reposted by Anna Kalisvaart
new out in Nature www.nature.com/articles/d41...
Compression causes cancer cells to start spreading
The switch between proliferation and invasion is triggered by mechanical force.
www.nature.com
September 6, 2025 at 12:50 PM
new out in Nature www.nature.com/articles/d41...
Reposted by Anna Kalisvaart
After a #stroke, patients typically undergo extensive #rehabilitation and a slow journey to recover the ability to do everyday tasks. However, ASNR Past President Dr. Tom Carmichael is developing a drug to produce the same effects as rehabilitation and could augment or replace rehab after a stroke.
A Pill to Heal the Brain Could Revolutionize Neuroscience
www.nytimes.com
September 5, 2025 at 3:35 PM
After a #stroke, patients typically undergo extensive #rehabilitation and a slow journey to recover the ability to do everyday tasks. However, ASNR Past President Dr. Tom Carmichael is developing a drug to produce the same effects as rehabilitation and could augment or replace rehab after a stroke.
Reposted by Anna Kalisvaart
Scientists discover the secret behind the shrew’s amazing ability to shrink their brains 🧠
The clever trick sheds unwanted weight without compromising too much on cognition.
Find the 5-letter word 👇
Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al
www.ab.mpg.de/743885/news_...
The clever trick sheds unwanted weight without compromising too much on cognition.
Find the 5-letter word 👇
Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al
www.ab.mpg.de/743885/news_...
Rare seasonal brain shrinkage in shrews is driven by water loss, not cell death
Common shrews are one of only a handful of mammals known to flexibly shrink and regrow their brains. This rare seasonal cycle, known as Dehnel’s phenomenon, has puzzled scientists for decades. A study...
www.ab.mpg.de
September 1, 2025 at 8:41 PM
Scientists discover the secret behind the shrew’s amazing ability to shrink their brains 🧠
The clever trick sheds unwanted weight without compromising too much on cognition.
Find the 5-letter word 👇
Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al
www.ab.mpg.de/743885/news_...
The clever trick sheds unwanted weight without compromising too much on cognition.
Find the 5-letter word 👇
Study by @cecibaldoni.bsky.social Dechmann Lab #shrewcrew et al
www.ab.mpg.de/743885/news_...
Reposted by Anna Kalisvaart
New review from Lennol, @maudgratuze.bsky.social and colleagues @inp-marseille.bsky.social assesses all the available evidence regarding how two crucial elements are intertwined in #Alzheimers disease pathophysiology: tau and apoE. rupress.org/jem/article/...
August 26, 2025 at 4:06 PM
New review from Lennol, @maudgratuze.bsky.social and colleagues @inp-marseille.bsky.social assesses all the available evidence regarding how two crucial elements are intertwined in #Alzheimers disease pathophysiology: tau and apoE. rupress.org/jem/article/...
Reposted by Anna Kalisvaart
Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.
August 27, 2025 at 3:24 AM
Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.
Reposted by Anna Kalisvaart
Rainbow retinas! While at @mblscience.bsky.social
I had the opportunity to check out frog and octopus retinas using super neat birefringence microscopy invented by Michael Shribak, with student Jenna Tijerina. The vertebrate inner retina is so optically clear compared to the outer segments! 🧪🐸🐙👀
I had the opportunity to check out frog and octopus retinas using super neat birefringence microscopy invented by Michael Shribak, with student Jenna Tijerina. The vertebrate inner retina is so optically clear compared to the outer segments! 🧪🐸🐙👀
August 22, 2025 at 1:02 AM
Rainbow retinas! While at @mblscience.bsky.social
I had the opportunity to check out frog and octopus retinas using super neat birefringence microscopy invented by Michael Shribak, with student Jenna Tijerina. The vertebrate inner retina is so optically clear compared to the outer segments! 🧪🐸🐙👀
I had the opportunity to check out frog and octopus retinas using super neat birefringence microscopy invented by Michael Shribak, with student Jenna Tijerina. The vertebrate inner retina is so optically clear compared to the outer segments! 🧪🐸🐙👀
Reposted by Anna Kalisvaart
New pre-print on sex differences in the choroid plexus- the 🧠's fluid secretion organ. Important differences in secretory signaling & immune compartments that can impact the 🧠 in health & disease. @karol-kaiser.bsky.social@violesilvar.bsky.social Luca von Allmen. 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Choroid plexus sex differences in secretory signalling and immune compartments
The choroid plexus (ChP)- cerebrospinal fluid (CSF) axis is emerging as a key regulator of the brain environment. The ChP is a multi-functional structure, which forms the blood-CSF barrier, and acts a...
www.biorxiv.org
August 20, 2025 at 1:36 PM
New pre-print on sex differences in the choroid plexus- the 🧠's fluid secretion organ. Important differences in secretory signaling & immune compartments that can impact the 🧠 in health & disease. @karol-kaiser.bsky.social@violesilvar.bsky.social Luca von Allmen. 🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anna Kalisvaart
Last year I calculated how much money it cost to use my bike as my primary mode of transportation.
It was less than 2k, and that’s on the high end for most people, as I don’t do much of my own maintenance. #YEGbike
It was less than 2k, and that’s on the high end for most people, as I don’t do much of my own maintenance. #YEGbike
August 21, 2025 at 3:58 AM
Last year I calculated how much money it cost to use my bike as my primary mode of transportation.
It was less than 2k, and that’s on the high end for most people, as I don’t do much of my own maintenance. #YEGbike
It was less than 2k, and that’s on the high end for most people, as I don’t do much of my own maintenance. #YEGbike
Reposted by Anna Kalisvaart
this is your periodic reminder that young neuroscientist Zoe thought that the "squid giant axon" was actually the "giant squid axon" and it will forever make me giggle
THE COLOSSAL SQUID IS MASSIVE. MUCH BIGGER THAN PEOPLE THOUGHT. THEY SAID IT WAS A MYTH — WRONG. I’VE SEEN IT. TOTALLY DOMINATES THE OCEAN. OTHER SQUIDS? VERY WEAK. VERY SAD.
August 18, 2025 at 2:49 PM
this is your periodic reminder that young neuroscientist Zoe thought that the "squid giant axon" was actually the "giant squid axon" and it will forever make me giggle
Reposted by Anna Kalisvaart
"It didn’t happen overnight, but Paris is forever changed, and now local residents of the French capital are reaping the rewards. Top of list? Cleaner air. A lot cleaner."
momentummag.com/paris-proves...
momentummag.com/paris-proves...
Paris Cycling Investment Helps Cut Pollution in Half
So how did Paris, once choked with vehicle traffic and notorious for its pollution, pull off such a turnaround?
momentummag.com
August 15, 2025 at 2:58 PM
"It didn’t happen overnight, but Paris is forever changed, and now local residents of the French capital are reaping the rewards. Top of list? Cleaner air. A lot cleaner."
momentummag.com/paris-proves...
momentummag.com/paris-proves...
Reposted by Anna Kalisvaart
Reposted by Anna Kalisvaart
Painting phase of this “poster” is done! #SciArt #LaurierBiology
August 14, 2025 at 12:31 PM
Painting phase of this “poster” is done! #SciArt #LaurierBiology
Reposted by Anna Kalisvaart
Systematic reviewers have a 10.7% error rate when screening papers for potential inclusion.
In other words, about 1 in 9 abstracts are categorised incorrectly (i.e., false inclusion or false exclusion). This really drives home the benefit of having at least two screeners
In other words, about 1 in 9 abstracts are categorised incorrectly (i.e., false inclusion or false exclusion). This really drives home the benefit of having at least two screeners
Error rates of human reviewers during abstract screening in systematic reviews
Background Automated approaches to improve the efficiency of systematic reviews are greatly needed. When testing any of these approaches, the criterion standard of comparison (gold standard) is usuall...
doi.org
August 13, 2025 at 8:04 AM
Systematic reviewers have a 10.7% error rate when screening papers for potential inclusion.
In other words, about 1 in 9 abstracts are categorised incorrectly (i.e., false inclusion or false exclusion). This really drives home the benefit of having at least two screeners
In other words, about 1 in 9 abstracts are categorised incorrectly (i.e., false inclusion or false exclusion). This really drives home the benefit of having at least two screeners