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New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬

An amazing set of resources for all scientists working on the brain!

🧠 Immersive feature:
www.nature.com/immersive/d4...

🧠 Perspective:
www.nature.com/articles/s41...

Cover of this week's Nature showing a brain rendering

Cover caption from the journal:
Brain development:
Our ability to process information into complex emotions, behaviours and decisions relies on the rich diversity of cell types that make up the human brain. Uncovering the molecular and cellular events that take place during brain development could reveal not only the mechanisms that give rise to this diversity but also shed light on how this process might go awry in neurodevelopmental disorders such as autism and schizophrenia. In this week’s issue, the BRAIN Initiative Cell Atlas Network (BICAN) builds on its previous work creating atlases of cell types in the adult mouse, non-human primate (NHP) and human brains to present cell-type atlases of the developing human, mouse and NHP brains. Across a suite of papers, nine of which are published in Nature, the researchers uncover the complex programs through which cell types emerge during brain development in humans and animals, revealing both the shared and unique features of the human brain. The latest work, along with future research directions, is summed up in a Perspective article by Tomasz Nowakowski and colleagues

November 5, 2025 at 6:53 PM

Reposted by Barbara Marte

Rob Clarke

@robclarkelab.bsky.social

Really happy to share a link to our work showing that anti-progestin therapy could help prevent breast cancer before menopause.
Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/...
Brilliant team science

Anti-progestin therapy targets hallmarks of breast cancer risk

Nature - Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing...

urldefense.com

November 5, 2025 at 9:07 PM

Reposted by Barbara Marte

Nature Portfolio

@natureportfolio.nature.com

Draft atlases of the developing brain of humans and other mammals are presented in a collection of papers from BICAN published in Nature. These resources combine single-cell and spatial technologies to track how brain cell types emerge, diversify, and organize during development. 🧪

BICAN: A cell census of the developing human brain

Building on their landmark efforts to create cell-type atlases of adult brains using single-cell and spatial genomics technologies, researchers in the BRAIN ...

go.nature.com

November 5, 2025 at 11:47 PM

Barbara Marte

@barbmarte.bsky.social

new out in Nature: BICAN: A cell census of the developing human brain
www.nature.com/collections/...

BICAN: A cell census of the developing human brain

Building on their landmark efforts to create cell-type atlases of adult brains using single-cell and spatial genomics technologies, researchers in the BRAIN ...

www.nature.com

November 6, 2025 at 7:43 AM

Barbara Marte

@barbmarte.bsky.social

new out in Nature, the Breast Cancer-Anti-Progestin Prevention Study 1 (BC-APPS1; NCT02408770)
www.nature.com/articles/s41...

Anti-progestin therapy targets hallmarks of breast cancer risk - Nature

Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing epithelial–stromal remode...

www.nature.com

November 6, 2025 at 7:42 AM

Barbara Marte

@barbmarte.bsky.social

new out in Nature, targeting FSP1 to trigger ferroptosis
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Targeting FSP1 triggers ferroptosis in lung cancer - Nature

The ferroptosis suppressor protein FSP1 has a critical role in ferroptosis protection of tumours across multiple in vivo models and is linked to worse prognosis in human lung adenocarcinoma, suggestin...

www.nature.com

November 6, 2025 at 7:39 AM

Reposted by Barbara Marte

Magdalena Skipper

@magdalenaskipper.bsky.social

In praise of fundamental research
Our editorial this week argues that I n these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different
🧪
@nature.com
www.nature.com/articles/d41...

From MRI to Ozempic: breakthroughs that show why fundamental research must be protected

In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.

www.nature.com

October 30, 2025 at 1:53 PM

Reposted by Barbara Marte

Magdalena Skipper

@magdalenaskipper.bsky.social

We asked physicists which are the sci-fi films they like the most - two were consistently highlighted in interviews for their depictions of science: 2014’s Interstellar and 2006’s The Prestige — both of which were directed and co-written by Christopher Nolan
🧪
www.nature.com/articles/d41...