Wouter De Coster
@wdecoster.bsky.social
Dad. Scientist at VIB. Bioinformatics postdoc. Sequencing technologies enthusiastic. Geneticist. He/him.
We are excited to have @minomatt.bsky.social as a keynote speaker at the Flanders Nanopore Day, alongside a wide range of @nanoporetech.com topics, spanning from microbes to plants to humans. All information - including free registration and free PromethION sequencing - at nanoporeflanders.be
Flanders Nanopore Day 2026 - Flanders Nanopore Day
The Flanders Nanopore Day - April 17th, 2026
nanoporeflanders.be
January 23, 2026 at 8:29 AM
We are excited to have @minomatt.bsky.social as a keynote speaker at the Flanders Nanopore Day, alongside a wide range of @nanoporetech.com topics, spanning from microbes to plants to humans. All information - including free registration and free PromethION sequencing - at nanoporeflanders.be
Reposted by Wouter De Coster
Yesterday it was cows using tools, today its penguins using satellite imagery.
January 20, 2026 at 6:44 PM
Yesterday it was cows using tools, today its penguins using satellite imagery.
Reposted by Wouter De Coster
Reposted by Wouter De Coster
Oh wow: Cryo-EM structure of #TAF15 filaments from postmortem #FTLD brains by the group of Ben Ryskeldi-Falcon at the @mrclmb.bsky.social. What an amazing tour-de-force!! 🤯
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
January 13, 2026 at 6:48 PM
Oh wow: Cryo-EM structure of #TAF15 filaments from postmortem #FTLD brains by the group of Ben Ryskeldi-Falcon at the @mrclmb.bsky.social. What an amazing tour-de-force!! 🤯
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Join us at the Flanders Nanopore Day conference on April 17th in Antwerp, organized together with @nanoporetech.com! Details are available at nanoporeflanders.be, including registration (free), abstract submission, and project prizes with free PromethION sequencing for two selected projects.
Flanders Nanopore Day 2026 - Flanders Nanopore Day
The Flanders Nanopore Day - April 17th, 2026
nanoporeflanders.be
January 13, 2026 at 8:58 AM
Join us at the Flanders Nanopore Day conference on April 17th in Antwerp, organized together with @nanoporetech.com! Details are available at nanoporeflanders.be, including registration (free), abstract submission, and project prizes with free PromethION sequencing for two selected projects.
Reposted by Wouter De Coster
#Iran is in the middle of #REVOLUTION. This isn't about inflation. It's about 47 years of oppression.
Listen to the chants: "death to the dictator," calls for regime change, and demands for the Shah's return.
Be the voice of the Iranian people.
#DigitalBlackoutIran
Listen to the chants: "death to the dictator," calls for regime change, and demands for the Shah's return.
Be the voice of the Iranian people.
#DigitalBlackoutIran
January 10, 2026 at 9:15 AM
#Iran is in the middle of #REVOLUTION. This isn't about inflation. It's about 47 years of oppression.
Listen to the chants: "death to the dictator," calls for regime change, and demands for the Shah's return.
Be the voice of the Iranian people.
#DigitalBlackoutIran
Listen to the chants: "death to the dictator," calls for regime change, and demands for the Shah's return.
Be the voice of the Iranian people.
#DigitalBlackoutIran
Reposted by Wouter De Coster
What genetic change to Indian wheat led to superior baking in a tandoor?
A naan sense mutation
A naan sense mutation
January 10, 2026 at 12:07 AM
What genetic change to Indian wheat led to superior baking in a tandoor?
A naan sense mutation
A naan sense mutation
Reposted by Wouter De Coster
Nicolás Maduro Charged With Felony Oil Possession
January 5, 2026 at 7:00 PM
Nicolás Maduro Charged With Felony Oil Possession
Reposted by Wouter De Coster
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social as usual not pulling any punches
@dereklowe.bsky.social as usual not pulling any punches
Last Year, and the Year to Come
www.science.org
January 5, 2026 at 9:27 AM
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social as usual not pulling any punches
@dereklowe.bsky.social as usual not pulling any punches
Reposted by Wouter De Coster
and the winner of the "2025 best thing on Internet" has just arrived
neal.fun/size-of-life/
@carlbergstrom.com
neal.fun/size-of-life/
@carlbergstrom.com
Size of Life
From an amoeba to a blue whale
neal.fun
December 23, 2025 at 4:07 PM
and the winner of the "2025 best thing on Internet" has just arrived
neal.fun/size-of-life/
@carlbergstrom.com
neal.fun/size-of-life/
@carlbergstrom.com
Reposted by Wouter De Coster
AI ran our office vending machine for several weeks. It lost hundreds of dollars, gave away a PlayStation, bought a live fish—and taught us a lot about AI agents, writes Joanna Stern.
We Let AI Run Our Office Vending Machine. It Lost Hundreds of Dollars.
An AI agent ran a snack operation in the WSJ newsroom. It gave away a free PlayStation, ordered a live fish—and taught us lessons about the future of AI.
on.wsj.com
December 18, 2025 at 11:06 AM
AI ran our office vending machine for several weeks. It lost hundreds of dollars, gave away a PlayStation, bought a live fish—and taught us a lot about AI agents, writes Joanna Stern.
Reposted by Wouter De Coster
HIRING ALERT!!! 💥
We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬
jobs.vib.be/j/128109/pos...
We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬
jobs.vib.be/j/128109/pos...
Postdoctoral Researcher in Computational Genomics of Alzheimers Disease - VIB
Description
TheSleegers labat the VIB-UAntwerp Center for Molecular Neurology Belgium, is seeking a highly motivated and talented postdoctoral r
jobs.vib.be
December 3, 2025 at 3:06 PM
HIRING ALERT!!! 💥
We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬
jobs.vib.be/j/128109/pos...
We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬
jobs.vib.be/j/128109/pos...
Reposted by Wouter De Coster
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
1/n
Intro to Bedder – The Quinlan Lab
quinlanlab.org
December 2, 2025 at 2:28 AM
Does someone know if there public @nanoporetech.com or @pacbio.bsky.social genome sequencing data from individuals with pathogenic repeat expansions?
November 27, 2025 at 11:38 AM
Does someone know if there public @nanoporetech.com or @pacbio.bsky.social genome sequencing data from individuals with pathogenic repeat expansions?
Reposted by Wouter De Coster
As new human assemblies become available on beta.ensembl.org - which human reference genome will you choose? This article explores the question with insights from Ensembl’s own Fergal Martin - www.nature.com/articles/s41...
#HumanGenomics #Pangenomes #ReferenceGenomes
#HumanGenomics #Pangenomes #ReferenceGenomes
Choose your human genome reference wisely - Nature Methods
Scientists can choose between multiple human genome references, and a pangenome reference is coming. Deciding what to use when is not quite straightforward.
www.nature.com
November 4, 2025 at 12:28 PM
As new human assemblies become available on beta.ensembl.org - which human reference genome will you choose? This article explores the question with insights from Ensembl’s own Fergal Martin - www.nature.com/articles/s41...
#HumanGenomics #Pangenomes #ReferenceGenomes
#HumanGenomics #Pangenomes #ReferenceGenomes
Reposted by Wouter De Coster
Did not expect to see disk space become an issue but after a disk clean up and restart I ended up with 243 and 244 gbp for these two @nanoporetech.com flowcells 🎉🚀🧬 💚🟩💚🟩💚🟩
November 4, 2025 at 12:10 PM
Did not expect to see disk space become an issue but after a disk clean up and restart I ended up with 243 and 244 gbp for these two @nanoporetech.com flowcells 🎉🚀🧬 💚🟩💚🟩💚🟩
Reposted by Wouter De Coster
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
October 21, 2025 at 9:36 AM
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
My current favorite strategy for using LLMs to code (specifically, GitHub Copilot agent mode) is to write a paragraph or more of instructions, and finish with "Do not start writing any code yet. First, tell me all the questions you still have about this plan".
October 21, 2025 at 12:47 PM
My current favorite strategy for using LLMs to code (specifically, GitHub Copilot agent mode) is to write a paragraph or more of instructions, and finish with "Do not start writing any code yet. First, tell me all the questions you still have about this plan".
Reposted by Wouter De Coster
Why yes Windows, I did want to save this email attachment in C:\Users\pbayer\AppData\Local\Microsoft\Olk\Attachments\ooa-6b0f86af-a548-4060-9a83-7d943fcaa440\157ef8591494ef374d2433d75c318962f8bc4054af4a1be24c8e02b89b6d5ec9
that's just a logical place for it
that's just a logical place for it
October 17, 2025 at 2:34 AM
Why yes Windows, I did want to save this email attachment in C:\Users\pbayer\AppData\Local\Microsoft\Olk\Attachments\ooa-6b0f86af-a548-4060-9a83-7d943fcaa440\157ef8591494ef374d2433d75c318962f8bc4054af4a1be24c8e02b89b6d5ec9
that's just a logical place for it
that's just a logical place for it
Reposted by Wouter De Coster
(forgetting the word for antibiotics) do i need cancel culture
October 11, 2025 at 7:09 PM
(forgetting the word for antibiotics) do i need cancel culture
Reposted by Wouter De Coster
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
October 5, 2025 at 9:08 AM
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
We are hiring a postdoctoral researcher to identify genes involved in frontotemporal dementia using short- and long-read sequencing data. More information is available at jobs.vib.be/j/124543/pos....
Postdoctoral researcher - VIB
The Laboratory of Advanced and Translational Neurogenomics at the VIB-Center for Molecular Neurology, led by Dr. Rosa Rademakers, is seeking a highly motivated and talented postdoctoral researcher to ...
jobs.vib.be
September 26, 2025 at 8:58 AM
We are hiring a postdoctoral researcher to identify genes involved in frontotemporal dementia using short- and long-read sequencing data. More information is available at jobs.vib.be/j/124543/pos....
Reposted by Wouter De Coster
NEWS! Nation capable of spotting spurious link between paracetamol and autism still baffled by obvious link between guns and mass shootings
Nation capable of spotting spurious link between paracetamol and autism still baffled by obvious link between guns and mass shootings
The United States has once again demonstrated its unique talent for scientific deduction by confidently declaring there may be a link between pregnant women taking paracetamol and children developi…
buff.ly
September 23, 2025 at 7:18 AM
NEWS! Nation capable of spotting spurious link between paracetamol and autism still baffled by obvious link between guns and mass shootings
Reposted by Wouter De Coster
minimap2.com is potentially a phishing site. Please don't use anything from that website.
github.com/lh3/minimap2...
github.com/lh3/minimap2...
Phishing site : minimap2.com · Issue #1316 · lh3/minimap2
Not sure how to label this one, but I have come across a website minimap2.com which appears to be AI generated but is serving it's own copy of the Github repository. If you search the address or em...
github.com
September 9, 2025 at 3:40 PM
minimap2.com is potentially a phishing site. Please don't use anything from that website.
github.com/lh3/minimap2...
github.com/lh3/minimap2...
Reposted by Wouter De Coster
Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.
Ie: it's not us (Samtools team)! Be warned
Ie: it's not us (Samtools team)! Be warned
September 15, 2025 at 8:40 AM
Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.
Ie: it's not us (Samtools team)! Be warned
Ie: it's not us (Samtools team)! Be warned