Sleegers Lab
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sleegerslab.bsky.social
Sleegers Lab
@sleegerslab.bsky.social
The Kristel Sleegers lab at VIB Center for Molecular Neurology and University of Antwerp, committed to increase insight in the complex genetics of Alzheimer’s disease.

https://uantwerpen.vib.be/group/KristelSleegers
Reposted by Sleegers Lab
Happy and honoured to receive the Fabrizio Caielli Award from the Carlo Besta Neurological Institute for our recent publication, “Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes” 🧠🧬

Many thanks to the selection committee for this recognition.

🔗 tinyurl.com/5y7nwp34
December 19, 2025 at 3:34 PM
Through the Flemish Cognitive Compass, we can link genetic profiles with blood biomarkers and long-term follow-up at population level. Thankful for the opportunity to contribute to such a collaborative and forward-looking effort!
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cmn.sites.vib.be
December 18, 2025 at 4:26 PM
Over the past months, we have mentioned our 1000 Healthy Elderly study quite often. This article puts the study in the perspective of the most important people in our study: the participants 🧓

biovox.eu/before-the-f...
Before the Fall: Catching Cognitive Decline Early with Citizen Science - BioVox
In Antwerp, a unique cohort of volunteers is helping to solve one of our most urgent medical challenges: the early detection of dementia.
biovox.eu
December 16, 2025 at 3:44 PM
Extremely thankful to have our Senior Research Project (with Julie van der Zee and @verwilt.bsky.social) funded in this @fwovlaanderen.bsky.social call! This marks a huge investment into our 1000 Healthy Elderly study in search of novel cell-free biomarkers! 🧠🧬🩸
December 15, 2025 at 8:54 AM
HIRING ALERT!!! 💥

We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬

jobs.vib.be/j/128109/pos...
Postdoctoral Researcher in Computational Genomics of Alzheimers Disease - VIB
Description TheSleegers labat the VIB-UAntwerp Center for Molecular Neurology Belgium, is seeking a highly motivated and talented postdoctoral r
jobs.vib.be
December 3, 2025 at 3:06 PM
Last Friday, we shared our research with 1st year Master's students at @uantwerpen.be during the Research Day! We loved their genuine interest and look forward to welcoming several of them to our lab next year.

Great to see Ph.D. students Kato and Ella share their love for science! 🧪
October 28, 2025 at 9:31 AM
Reposted by Sleegers Lab
The European Alzheimer & Dementia Biobank (EADB) unites cohorts across 18 countries to decode the genetics of Alzheimer’s disease. https://eadb.eu/
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.

#CMNcohorts #CMNconsortia
October 9, 2025 at 11:47 AM
One year in, nearly 200 re-inclusions and a clearer picture of healthy brain aging!

The 1000 Healthy Elderly Study has become a real engine for discovery.

Thanks to all of our volunteers and a special shout-out to Sofie Van de kerckhoven for the excellence at intake and sampling! bit.ly/4gV9TLk
October 7, 2025 at 11:36 AM
🚨 #PhD opportunity! Sleegers & Rademakers Labs are looking for a PhD candidate to develop biomarkers for neurological disorders by integrating genomics & transcriptomics data🧠🔬

@cmn-vib.bsky.social 📍 Antwerp, Belgium | 💡 Genetics • Bioinformatics • Neuroscience

Apply 👉 jobs.vib.be/j/124544/joi...
Joint PhD position on developing genetic risk scores as biomarkers for neurological disorders - VIB
The Rademakers team and the Sleegers team at the VIB-UAntwerp Center for Molecular Neurology, Belgium a
jobs.vib.be
October 2, 2025 at 11:57 AM
Reposted by Sleegers Lab
Our postdoc @verwilt.bsky.social is selected for the @scimingo.bsky.social PhD Cup for his research during his PhD! 💥 Let's see how his findings can impact Alzheimer's Disease 🧠🧬🩸

@fwovlaanderen.bsky.social @ugent-fge.bsky.social @cmn-vib.bsky.social @viblifesciences.bsky.social @uantwerpen.be
Over the moon to be selected for the Flemish #PhDCup 2025 for my research at @ugent-fge.bsky.social at the OncoRNALab with @jvdesomp.bsky.social and Pieter Mestdagh! @fwovlaanderen.bsky.social
🌪️ Storm aan talent op komst: ontdek de selectie van de Vlaamse #PhDCup 2025 🏆

Lees meer en ontdek alle kandidaten 👉 www.phdcup.be/nieuws/storm...

@uantwerpen.be @kuleuvenuniversity.bsky.social #uhasselt #ugent #vub @fwovlaanderen.bsky.social
September 10, 2025 at 8:08 AM
Reposted by Sleegers Lab
Over the moon to be selected for the Flemish #PhDCup 2025 for my research at @ugent-fge.bsky.social at the OncoRNALab with @jvdesomp.bsky.social and Pieter Mestdagh! @fwovlaanderen.bsky.social
September 10, 2025 at 7:35 AM
Reposted by Sleegers Lab
Big congrats to @verwilt.bsky.social‬ from the @sleegerslab.bsky.social‬ on his FWO fellowship! He’ll be mapping RNA and DNA in blood, CSF, even tear fluid, to develop non-invasive biomarkers for Alzheimer’s using long-read sequencing. https://tinyurl.com/ym6c8csr
June 30, 2025 at 10:00 AM
Ciao Milano! We are happy and excited to be here for #eshg2025 @eshg.bsky.social

Come find us during the oral and poster presentations by our team members Fahri Küçükali (@maegsul.bsky.social) & Celeste Laureyssen (@celestelaureyssen.bsky.social) today and tomorrow 🧬 🧠
May 24, 2025 at 9:18 AM
What a poster! Master’s student in our lab, Kato Nauwelaers, won third prize for her poster at NeuroDay 2025 @uantwerpen.be! Congrats Kato! 🎉
May 23, 2025 at 9:06 PM
Look at us! 🤩 We presented the excuting research going on in our lab at the @uantwerpen.be NeuroDay 2025. So great to with fellow neuroscientist! 🧠
May 22, 2025 at 11:40 AM
A new chapter in our lab has begun! Our postdoc @verwilt.bsky.social has received an FWO Junior Fellowship to look for non-invasive extracellular biomarkers for Alzheimer’s disease. Stay tuned for some cool research! @fwovlaanderen.bsky.social
YOU MUST BE KIDDING ME! 🥳 Extremely happy to be selected as a Junior FWO Postdoctoral fellowship! Stay tuned for novel extracellular biomarkers for Alzheimer’s disease! Can’t wait to jump in these three years! 🧠🩸🧬 #fwo #RNA #cfDNA #alzheimers @fwovlaanderen.bsky.social @sleegerslab.bsky.social
Fwo
There were 1038 applications for the junior fellowships and 439 for the senior fellowships. As a result, the success rate this year fell to 16.1% (-1.3%) for junior postdocs and 25.9% (-7.8%) for senior postdocs.
www.fwo.be
May 22, 2025 at 8:57 AM
Reposted by Sleegers Lab
YOU MUST BE KIDDING ME! 🥳 Extremely happy to be selected as a Junior FWO Postdoctoral fellowship! Stay tuned for novel extracellular biomarkers for Alzheimer’s disease! Can’t wait to jump in these three years! 🧠🩸🧬 #fwo #RNA #cfDNA #alzheimers @fwovlaanderen.bsky.social @sleegerslab.bsky.social
Fwo
There were 1038 applications for the junior fellowships and 439 for the senior fellowships. As a result, the success rate this year fell to 16.1% (-1.3%) for junior postdocs and 25.9% (-7.8%) for senior postdocs.
www.fwo.be
May 22, 2025 at 8:04 AM
Reposted by Sleegers Lab
7 years in the making... 1.6 liters of blood and 11 billion sequencing reads to compare 456 extracellular transcriptomes.

Our best practices for blood plasma extracellular RNA profiling have been published as a peer-reviewed article.

communities.springernature.com/posts/the-ro...
The road to discovery - a collaborative effort towards new insights in blood plasma RNA profiling
After more than seven years of research, our extracellular RNA quality control (exRNAQC) study has culminated in a scientific publication. This milestone is not just about sharing new findings – it re...
communities.springernature.com
May 15, 2025 at 6:41 PM
Reposted by Sleegers Lab
Finally out! The exRNAQC Consortium is very happy to present this milestone benchmark on blood tubes and RNA extraction kits for extracellular RNA research out in @natcomms.nature.com! The associated blog post tells a story of a lengthy effort and multi-facetted collaboration🩸🧬
May 16, 2025 at 9:35 AM
Our lab’s recent hackathon ☕🧠💻 was a success: three packed days, one awesome crew, endless ideas. We built fresh neurogenomics tools and leveled-up team vibes 🚀🧬
April 22, 2025 at 4:39 PM
🚨 PhD Position Alert! 🚨
We're excited to announce a collaborative PhD opportunity with @uantwerpen.be LEMP, investigating the role of mucin splicing in colorectal cancer. If you're passionate about RNA biology, omics, and translational research, this could be the perfect fit!
April 3, 2025 at 3:02 PM
Reposted by Sleegers Lab
Exciting news! Our paper on GWAS gene prioritization for Creutzfeldt-Jakob Disease is now published in Brain! 🧠🧬 @brain1878.bsky.social

We leverage eQTL and pQTL catalogues to identify prioritized risk genes with potential roles in prion disease.

Check it out here: academic.oup.com/brain/advanc...
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu
academic.oup.com
February 13, 2025 at 1:23 PM
Very happy to see our review on Alzheimer's disease rare genetic variants published in @natrevneurol.bsky.social! 🧠🧬

Huge congrats to our PhD student @laradedeyn.bsky.social 🎉👏✨

www.nature.com/articles/s41...
February 5, 2025 at 4:07 PM