Benjamin Schuster-Böckler
@dagams.bsky.social
Group leader at the Ludwig Institute for Cancer Research in Oxford. Computational genomics and bioinformatics.
Also find me on genomic.social, a free and non-profit Mastodon instance for genomics (@bensb@genomic.social)
Also find me on genomic.social, a free and non-profit Mastodon instance for genomics (@bensb@genomic.social)
Reposted by Benjamin Schuster-Böckler
Many congratulations to Lauren Murphy!
Congratulations to the 2025 RDM Graduate Prize winner - Lauren Murphy 🎉
The annual RDM Graduate Prize is awarded to current or recently graduated students of RDM supervisors for exceptional achievement in their research.
Read more about Lauren's work 👇
shorturl.at/QWaty
@imm.ox.ac.uk
The annual RDM Graduate Prize is awarded to current or recently graduated students of RDM supervisors for exceptional achievement in their research.
Read more about Lauren's work 👇
shorturl.at/QWaty
@imm.ox.ac.uk
2025 RDM Graduate Prize winner
Congratulations to the 2025 RDM Graduate Prize Winner; Lauren Murphy.
shorturl.at
January 16, 2026 at 9:23 AM
Many congratulations to Lauren Murphy!
Reposted by Benjamin Schuster-Böckler
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 16, 2026 at 6:33 PM
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
Reposted by Benjamin Schuster-Böckler
Put your high-level hypotheses in a stand-alone coloured box that no reviewers can miss
January 16, 2026 at 10:47 AM
Put your high-level hypotheses in a stand-alone coloured box that no reviewers can miss
Reposted by Benjamin Schuster-Böckler
🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist!
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
Job offer 2026.pdf
drive.google.com
January 12, 2026 at 3:57 PM
🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist!
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
Reposted by Benjamin Schuster-Böckler
Vincenzo D’Angiolella @vdangioe3lab.bsky.social et al show that the little-studied F-box protein FBXO42 exerts many of its cellular roles by limiting PP4 phosphatase activity to ensure proper DNA damage signaling
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Client Challenge
link.springer.com
January 9, 2026 at 1:06 PM
Vincenzo D’Angiolella @vdangioe3lab.bsky.social et al show that the little-studied F-box protein FBXO42 exerts many of its cellular roles by limiting PP4 phosphatase activity to ensure proper DNA damage signaling
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Benjamin Schuster-Böckler
Epigenetics that matters! Very cool work on hard to hard-to-access cell types . Finally some solid epigenetics examples that should be used in textbooks! Congrats to Mathieu and team @embl.org Rome!
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
www.biorxiv.org
January 7, 2026 at 3:53 PM
Epigenetics that matters! Very cool work on hard to hard-to-access cell types . Finally some solid epigenetics examples that should be used in textbooks! Congrats to Mathieu and team @embl.org Rome!
The Luwig Institute for Cancer Research in Oxford is offering a generously core-funded "associate member" fellowship for mid(-ish) career researchers in any area of cancer research that would complement our existing portfolio: www.ludwig.ox.ac.uk/news/express...
Please share!
Please share!
Expression of interest: Associate Member/Professor
The University of Oxford and the Ludwig Institute for Cancer Research are adding to our growing group of cancer researchers. We are seeking individuals at mid-stage career stage with interest in joini...
www.ludwig.ox.ac.uk
December 25, 2025 at 12:37 PM
The Luwig Institute for Cancer Research in Oxford is offering a generously core-funded "associate member" fellowship for mid(-ish) career researchers in any area of cancer research that would complement our existing portfolio: www.ludwig.ox.ac.uk/news/express...
Please share!
Please share!
T'is the season of lab lunch photos with paper crowns! Maybe we'll add Christmas jumpers next year 😉
December 17, 2025 at 10:28 PM
T'is the season of lab lunch photos with paper crowns! Maybe we'll add Christmas jumpers next year 😉
Reposted by Benjamin Schuster-Böckler
this is not behavior becoming of a FIFA Peace Prize recipient.
December 15, 2025 at 8:18 PM
this is not behavior becoming of a FIFA Peace Prize recipient.
Missing my flight back to London because a close relative's in hospital. Against all odds, a kind human at British Airways changed my flight to tomorrow for free. I wish I could thank them more. That was truly first class customer service #kindnessofstrangers
December 15, 2025 at 6:33 PM
Missing my flight back to London because a close relative's in hospital. Against all odds, a kind human at British Airways changed my flight to tomorrow for free. I wish I could thank them more. That was truly first class customer service #kindnessofstrangers
Reposted by Benjamin Schuster-Böckler
Check out our latest work on Triplet Repeats!
REV1 inhibition enhances trinucleotide repeat mutagenesis url: royalsocietypublishing.org/rsob/article...
REV1 inhibition enhances trinucleotide repeat mutagenesis url: royalsocietypublishing.org/rsob/article...
REV1 inhibition enhances trinucleotide repeat mutagenesis
Abstract. Trinucleotide repeat instability has been implicated in the pathogenesis of numerous neurodegenerative disorders. While germline expansions desta
royalsocietypublishing.org
December 11, 2025 at 9:11 PM
Check out our latest work on Triplet Repeats!
REV1 inhibition enhances trinucleotide repeat mutagenesis url: royalsocietypublishing.org/rsob/article...
REV1 inhibition enhances trinucleotide repeat mutagenesis url: royalsocietypublishing.org/rsob/article...
Reposted by Benjamin Schuster-Böckler
We are hiring!
We are looking for a Postdoc to drive our efforts on using tissue clearing for 3D histopathology.
@erturklab.bsky.social
#Histopathology #TissueClearing #PostDoc
www.linkedin.com/feed/update/...
We are looking for a Postdoc to drive our efforts on using tissue clearing for 3D histopathology.
@erturklab.bsky.social
#Histopathology #TissueClearing #PostDoc
www.linkedin.com/feed/update/...
#histopathology #tissueclearing #lightsheetmicroscopy #postdoc #sciencecareers #munich | Ali Maximilian Ertürk
Hiring: PostDoc in Tissue Clearing & 3D Histopathology 🧪🖥️
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
...
www.linkedin.com
December 8, 2025 at 7:18 AM
We are hiring!
We are looking for a Postdoc to drive our efforts on using tissue clearing for 3D histopathology.
@erturklab.bsky.social
#Histopathology #TissueClearing #PostDoc
www.linkedin.com/feed/update/...
We are looking for a Postdoc to drive our efforts on using tissue clearing for 3D histopathology.
@erturklab.bsky.social
#Histopathology #TissueClearing #PostDoc
www.linkedin.com/feed/update/...
Reposted by Benjamin Schuster-Böckler
As a deliberate and successful attempt to get everyone talking about a questionable metric, Spotify ages and epigenetic clocks are pretty indistinguishable.
December 6, 2025 at 1:47 PM
As a deliberate and successful attempt to get everyone talking about a questionable metric, Spotify ages and epigenetic clocks are pretty indistinguishable.
Reposted by Benjamin Schuster-Böckler
There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant.
research.pasteur.fr/en/call/mid-...
research.pasteur.fr/en/call/mid-...
Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research
Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...
research.pasteur.fr
November 27, 2025 at 1:38 PM
There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant.
research.pasteur.fr/en/call/mid-...
research.pasteur.fr/en/call/mid-...
Reposted by Benjamin Schuster-Böckler
How a grassy Oxfordshire field became an illegal mountain of waste in just months
How a grassy Oxfordshire field became an illegal mountain of waste in just months
Satellite images reveal how a grassy field in Oxfordshire was transformed into an illegal waste site in just a few months.
news.sky.com
November 17, 2025 at 4:46 PM
How a grassy Oxfordshire field became an illegal mountain of waste in just months
Reposted by Benjamin Schuster-Böckler
Calling cancer data scientists! 📊 💽 🧮
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...
Data Scientist in Sutton | The Institute of Cancer Research
View details and apply for this Data Scientist vacancy in Sutton.
Salary : Salary range £39,805 to £53,500 (Dependent on experience )
Reporting to: Professor Trevor Gra...
jobs.icr.ac.uk
November 13, 2025 at 2:59 PM
Calling cancer data scientists! 📊 💽 🧮
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...
Reposted by Benjamin Schuster-Böckler
Regretfully (for the sake of the authors and journal staff), I have this morning declined an invitation to review for a @royalsociety.org journal because of the Society’s continued refusal to stand up for its values in dealing with Elon Musk FRS.
November 14, 2025 at 8:02 AM
Regretfully (for the sake of the authors and journal staff), I have this morning declined an invitation to review for a @royalsociety.org journal because of the Society’s continued refusal to stand up for its values in dealing with Elon Musk FRS.
Reposted by Benjamin Schuster-Böckler
A Sharon Begley byline, almost 5 years after her death.
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 8, 2025 at 1:39 PM
A Sharon Begley byline, almost 5 years after her death.
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
Reposted by Benjamin Schuster-Böckler
The costs of the UK’s Global Talent Visa looks a trifle high in comparison to competitor countries - largely through the Immigration Health Surcharge (which critics say is a form of double taxation as they contribute to the NHS through normal tax on their earnings)
October 21, 2025 at 5:57 AM
The costs of the UK’s Global Talent Visa looks a trifle high in comparison to competitor countries - largely through the Immigration Health Surcharge (which critics say is a form of double taxation as they contribute to the NHS through normal tax on their earnings)
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
October 21, 2025 at 9:36 AM
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
Reposted by Benjamin Schuster-Böckler
Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...
Somatic mutation and selection at population scale - Nature
A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.
www.nature.com
October 8, 2025 at 4:31 PM
Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...
Reposted by Benjamin Schuster-Böckler
RIP John Gurdon
October 7, 2025 at 6:06 PM
RIP John Gurdon
I have a special memory of my one encounter with John Gurdon: In 2014, I attended a conference in Oxford where he gave a keynote. At lunch, the last free seat was next to him. We ended up having the most amazing 1h conversation about science and life in general. Very sad to hear of his passing.
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
October 7, 2025 at 9:01 PM
I have a special memory of my one encounter with John Gurdon: In 2014, I attended a conference in Oxford where he gave a keynote. At lunch, the last free seat was next to him. We ended up having the most amazing 1h conversation about science and life in general. Very sad to hear of his passing.
Reposted by Benjamin Schuster-Böckler
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 29, 2025 at 9:25 AM
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
This, 100%. The UK gov is self-destructing and handing the country to the fascists by trying to out-compete Reform on immigrant-bashing. I'm revolted, and deeply concerned, about this race to the bottom.
My family came here 50 years ago. They've worked, paid taxes, raised families, been good citizens.
My many colleagues and friends who were either born elsewhere, or their parents were, the same.
It's so offensive to be told you're here on sufferance.
My many colleagues and friends who were either born elsewhere, or their parents were, the same.
It's so offensive to be told you're here on sufferance.
Just fuck off with this. How about start the conversation by highlighting how much immigrants contribute to the UK - not least by propping up the NHS and social care system!
Also - forced volunteering is not volunteering, it's unpaid labour.
Also - forced volunteering is not volunteering, it's unpaid labour.
September 29, 2025 at 9:57 AM
This, 100%. The UK gov is self-destructing and handing the country to the fascists by trying to out-compete Reform on immigrant-bashing. I'm revolted, and deeply concerned, about this race to the bottom.