Radcliffe Department of Medicine
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Radcliffe Department of Medicine
@rdm.ox.ac.uk
We are a University of Oxford department specialising in cardiovascular medicine, metabolism, haematology and immunology. www.rdm.ox.ac.uk
Reposted by Radcliffe Department of Medicine
#WIMMReads: A new #review in Nature Reviews Immunology by Hal Drakesmith and Joe N Frost explores how #iron shapes immune responses in infection inflammation and cancer.
Read more 👇

#Immunology #Immunology #IronMetabolism #Infection
@rdm.ox.ac.uk @drakesmith-lab.bsky.social @medsci.ox.ac.uk
Iron and the immune system - Nature Reviews Immunology
Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate and adaptive cellular and ...
www.nature.com
December 18, 2025 at 9:28 AM
Almost every species on Earth fundamentally needs iron. This feature on the work led by @drakesmith-lab.bsky.social from @imm.ox.ac.uk reveals more about iron's complex role in shaping human health. www.ox.ac.uk/pulse/health...
Tackling iron deficiency
More than 1.2 billion people worldwide are so iron-deficient that they develop iron-deficiency anaemia. The consequences include fatigue, dizziness, hair loss, greater risk of pregnancy complications,...
www.ox.ac.uk
December 16, 2025 at 9:37 AM
Reposted by Radcliffe Department of Medicine
Reposted by Radcliffe Department of Medicine
Huge congratulations to Holly Russell who has been awarded a fellowship from the Lee Placito Medical Fund.

@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk

www.imm.ox.ac.uk/news/holly-r...
Holly Russell receives Lee Placito Research Fellowship
Congratulations to Holly Russell who has been awarded a fellowship from the Lee Placito Medical Fund.
www.imm.ox.ac.uk
December 9, 2025 at 1:57 PM
The @meassociation.org.uk is taking part in Big Give's #ChristmasChallenge this week to raise money to support a case-control study led by some of our researchers. The study will use MRI and Near-Infrared Spectroscopy to uncover what goes wrong in the muscles during Post-Exertional Malaise.
We’re taking part in Big Give’s #ChristmasChallenge from 2–9 December; every donation you make to the ME Association will be DOUBLED by Big Give!

Donate here: https://meassociation.org.uk/BigGive2025

#MECFS #MyalgicEncephalomyelitis #LongCovid #BigGive2025 #WhenRestIsntEnough #DoubleYourDonation
December 2, 2025 at 3:50 PM
Reposted by Radcliffe Department of Medicine
"It's beginning to look a lot like Gutmas!"

Congratulations to @vywien-lai.bsky.social on winning the MRF/MRC 2025 Festive Science Image Competition with these striking cross sections of gut tissue at different developmental stages 🧪🎄

@medresfdn.bsky.social @ukri.org @rdm.ox.ac.uk

Learn more 👇
It's beginning to look a lot like Gutmas!
Congratulations to Vy Wien Lai, whose image was chosen for 1st place in the MRC/MRF 2025 Festive Science Image Competition.
www.imm.ox.ac.uk
December 1, 2025 at 9:56 AM
Reposted by Radcliffe Department of Medicine
Don’t miss out on this opportunity- come and join us at the Oxford Organoid Hub working under the MRC-BHF REACT programme! If you love in vitro 3D models, the ❤️ and regenerative therapies, this is for you - apply by 18 Dec @oxforddpag.bsky.social @idrm.ox.ac.uk @rdm.ox.ac.uk
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob

Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
November 30, 2025 at 11:02 PM
Reposted by Radcliffe Department of Medicine
How much do you know about what’s going on in your gut? 🦠

That’s the question that a group of scientists, led by @anna-aulicino.bsky.social from the Simmons Group, asked attendees at ‘TECHWORKS’ - one of #IFOxford’s family zones this year.

Learn more 👇

@rdm.ox.ac.uk | @medsci.ox.ac.uk
Battle in the Gut at IF Oxford 2025
In October 2025, researchers from the MRC Translational Immune Discovery Unit led activities on researching gut bacteria at Oxford Science + Ideas Festival.
www.imm.ox.ac.uk
November 25, 2025 at 1:59 PM
Reposted by Radcliffe Department of Medicine
#WIMMReads: Researchers from the MRC Molecular Haematology Unit and the MRC WIMM Centre for Computational Biology review how #DNA sequence shapes the complex regulatory layers inside our cells.
Read more 👇

#Genomics
#3DGenome
#ComputationalBiology
@rdm.ox.ac.uk @medsci.ox.ac.uk
The emerging sequence grammar of 3D genome organisation - Human Genetics
The multiplexed layers of regulatory processes and mechanisms within a cell are, to a degree, encoded in our genome. Unravelling the relationship between DNA sequence and molecular processes is crucia...
doi.org
November 20, 2025 at 9:38 AM
We are delighted to welcome @profjdchalmers.bsky.social to @rdm.ox.ac.uk as the Rhodes Professor of Experimental Therapeutics and Clinical Pharmacology. James conducts clinical trials and translational research to understand airway disease and develop new therapies. www.rdm.ox.ac.uk/news/profess...
Professor James Chalmers to join the Radcliffe Department of Medicine
We are delighted to announce that Professor James Chalmers has been recruited to the statutory Rhodes Professorship of Experimental Therapeutics and Clinical Pharmacology at the University of Oxford. ...
www.rdm.ox.ac.uk
November 19, 2025 at 12:00 PM
Reposted by Radcliffe Department of Medicine
NEW: Researchers in the Vyas Group used TARGET-seq+ to uncover how drug resistance develops in new treatment for acute myeloid leukaemia - these findings could help identify patients likely to relapse & find ways to prevent or treat relapse 🧪

Learn more 👇

@rdm.ox.ac.uk @oxfordbrc.bsky.social
Study reveals how drug resistance develops early in targeted AML therapy
A new study led by researchers at the MRC Molecular Haematology Unit has shown that resistance to a targeted treatment for acute myeloid leukaemia (AML) can develop much earlier than expected.
www.imm.ox.ac.uk
November 17, 2025 at 1:26 PM
Reposted by Radcliffe Department of Medicine
#WIMMReads: New @nature.com study, led by the Simmons & Antanaviciute Groups, used advanced single-cell and spatial analysis techniques to map the cells that drive #Crohn's fistulas - paving the way for targeted treatments 🧪

Learn more 👇

@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk
Oxford scientists map the cells that drive Crohn’s disease fistulas
Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that dev...
www.imm.ox.ac.uk
November 13, 2025 at 9:34 AM
Great to hear @jojdavies.bsky.social on @bbc5live.bsky.social last week, talking about how his team have been able to see the most detailed view yet of DNA inside a cell.

This allows them to find where things go wrong in disease.

Listen again (from 26 mins) 👇
www.bbc.co.uk/sounds/play/...
5 Live Drive - 05/11/2025 - BBC Sounds
A round-up of the day's top news and sport with Clare McDonnell and Chris Warburton.
www.bbc.co.uk
November 11, 2025 at 11:30 AM
Professor Ellie Tzima has been awarded a highly competitive ERC Synergy Grant to investigate the enigmatic neurovascular interface of peripheral nerves – a critical but poorly understood junction between the nervous and vascular systems.

@erc.europa.eu

www.rdm.ox.ac.uk/news/profess...
Professor Ellie Tzima receives €10m to investigate the neurovascular interface of peripheral nerves
www.rdm.ox.ac.uk
November 7, 2025 at 11:18 AM
Scientists have the most detailed view yet of how DNA folds and functions inside living cells!

The breakthrough helps us understand how genetic differences lead to disease and opens up fresh routes for drug discovery 👇

shorturl.at/nQjsx

@jojdavies.bsky.social @imm.ox.ac.uk @medsci.ox.ac.uk
Oxford scientists capture genome’s structure in unprecedented detail
RDM scientists have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on.
shorturl.at
November 6, 2025 at 11:18 AM
Reposted by Radcliffe Department of Medicine
We are thrilled to share that Dr Abdullah Khan has received a Wellcome Career Development Award for his research on age-related immune dysfunction.

Congratulations, Abs! 👏

www.imm.ox.ac.uk/news/abs-kha...
@rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk @abattacks.bsky.social
Abdullah Khan receives Wellcome Career Development Award
Congratulations are in order for Dr Abdullah (Abs) Khan, who has been awarded a Wellcome Career Development Award for his research on age-related immune dysfunction using human model systems.
www.imm.ox.ac.uk
November 4, 2025 at 10:11 AM
Congratulations to DPhil student Waleed Seddiq who has been awarded an UKEV MOVE Fellowship to advance heart disease research.

Read more 👇

shorturl.at/u1OfV
DPhil student awarded UKEV MOVE Fellowship to advance heart disease research
Congratulations to RDM DPhil student Waleed Seddiq, who has been awarded a MOVE Fellowship from the UK Society for Extracellular Vesicles (UKEV).
shorturl.at
October 20, 2025 at 2:45 PM
Reposted by Radcliffe Department of Medicine
Two weeks ago, researchers from across the world gathered in Oxford for "Unravelling T-Cell Recognition: Insights from Immunology and AI", a unique conference and hackathon exploring how advances in artificial intelligence can deepen understanding of T-cell biology.

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Unravelling T-Cell Recognition: Insights from Immunology and AI
From 29 September to 1 October 2025, researchers from across the world gathered in Oxford for a unique conference and hackathon exploring how advances in artificial intelligence can deepen understandi...
www.imm.ox.ac.uk
October 13, 2025 at 8:16 AM
Three RDM researchers have been awarded the title of Full Professor in the University's 2025 Recognition of Distinction exercise.

Congratulations to Beth Psaila, James Davies and Rajesh Kharbanda 🎉

Read more 👇

shorturl.at/S7vLA

@imm.ox.ac.uk @bethpsaila.bsky.social @jojdavies.bsky.social
October 1, 2025 at 7:56 AM
Congratulations to Professor Ellie Tzima who has joined an international team of scientists awarded an $8.5 million grant from the Leducq Foundation 🎉

The team will study Peripheral Artery Disease (PAD) and accelerate the development of new therapies.

Read more 👇

shorturl.at/z3mhI
Professor Ellie Tzima receives Leducq Foundation funding to tackle Peripheral Artery Disease
Professor Ellie Tzima from the Radcliffe Department of Medicine has joined an international team of scientists awarded an $8.5 million grant from the Leducq Foundation to study Peripheral Artery Disea...
shorturl.at
September 29, 2025 at 7:38 AM
A £10 million gift from the Bukhman Foundation will support ground-breaking research into #Type1Diabetes (T1D) @ox.ac.uk

This generous funding will accelerate progress towards better treatments and ultimately a cure.

www.rdm.ox.ac.uk/news/oxford-...
Oxford University to accelerate type 1 diabetes research and care with £10 million gift
The University of Oxford has announced a gift of £10 million from the Bukhman Foundation to support ground-breaking research into type 1 diabetes (T1D). This generous funding will establish the Bukhma...
www.rdm.ox.ac.uk
September 25, 2025 at 8:57 AM
Reposted by Radcliffe Department of Medicine
📽️ Check out our latest video, where we speak with the @drakesmith-lab.bsky.social and their collaborators in @oxuniearthsci.bsky.social & @biology.ox.ac.uk to find out how they're tackling iron deficiency - the world's most common nutritional deficiency 🧪

@rdm.ox.ac.uk | @ox.ac.uk

Watch here 👇
Tackling Iron Deficiency
YouTube video by MRC Weatherall Institute of Molecular Medicine
www.youtube.com
September 17, 2025 at 8:58 AM
Reposted by Radcliffe Department of Medicine
NEW: Oxford researchers link mini organs to show how immune cells race to the rescue after heart injury 🧪

@abattacks.bsky.social & colleagues linked cardiac and bone marrow organoids with a 3D-printed device to model this complex immune response.

Learn more 👇

@rdm.ox.ac.uk | @medsci.ox.ac.uk
Body-in-a-chip approach reveals how immune cells respond to heart injury
Oxford scientists build a connected, ‘multi-organoid’ platform that recreates immune recruitment to the heart, opening new avenues to probe disease and test therapies.
www.imm.ox.ac.uk
September 11, 2025 at 8:29 AM
Congratulations to Dr Christos Kotanidis who has been awarded the 2025 ESC Young Investigator Award in Preventative Cardiology at the European Society of Cardiology Congress in Madrid.

Read more 👇

shorturl.at/KU2Be
Christos Kotanidis wins ESC Young Investigator Award 2025 in Preventive Cardiology
Congratulations to Dr Christos Kotanidis, NIHR-funded Academic Clinical Lecturer in Cardiology, who has been awarded the 2025 ESC Young Investigator Award in Preventive Cardiology at the European Soci...
shorturl.at
September 8, 2025 at 12:42 PM