Chris Toepfer
@christoepfer.bsky.social
Associate Professor of Cardiovascular Science
@UniofOxford. Director of the Oxford Organoid Hub. Researching Inherited & acquired heart disease using human model systems.
@UniofOxford. Director of the Oxford Organoid Hub. Researching Inherited & acquired heart disease using human model systems.
Pinned
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
Thanks to the @oxfordharrington.bsky.social and FARA for their continued support of our work into mechanisms underlying the Friedreich’s Ataxia associated cardiomyopathy. Write up here: www.oxfordharrington.org/events-news/...
The Oxford-Harrington Rare Disease Centre Advances Discovery of Therapies for Friedreich’s Ataxia (FA)
The Oxford-Harrington Rare Disease Centre (‘OHC’) dedicated to creating new medicines for rare diseases, today announced that the FA Alliance Innovation Fund has awarded funding to five researchers
www.oxfordharrington.org
February 9, 2026 at 9:22 PM
Thanks to the @oxfordharrington.bsky.social and FARA for their continued support of our work into mechanisms underlying the Friedreich’s Ataxia associated cardiomyopathy. Write up here: www.oxfordharrington.org/events-news/...
Reposted by Chris Toepfer
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
Assaying the myosin super-relaxed state across muscle types, cells and proteins for understanding muscle biology and use in drug discovery - Nature Protocols
The Mant-ATP assay is a simple and accessible means for rapid quantitative assessment of the ratio of super-relaxed myosin to disordered relaxed myosin. This protocol provides a standardized methodolo...
www.nature.com
December 1, 2025 at 4:21 PM
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
December 1, 2025 at 4:27 PM
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
November 28, 2025 at 6:41 PM
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
A joy to present at the Oxford @thebhf.bsky.social Centre of Research Excellence annual symposium. Great discussions and a great opportunity to show some of the research happening around the Oxford Organoid Hub. @rdm.ox.ac.uk @simoesfilipa.bsky.social @idrm.ox.ac.uk
November 28, 2025 at 6:18 PM
A joy to present at the Oxford @thebhf.bsky.social Centre of Research Excellence annual symposium. Great discussions and a great opportunity to show some of the research happening around the Oxford Organoid Hub. @rdm.ox.ac.uk @simoesfilipa.bsky.social @idrm.ox.ac.uk