Chris Toepfer
@christoepfer.bsky.social
Associate Professor of Cardiovascular Science
@UniofOxford. Director of the Oxford Organoid Hub. Researching Inherited & acquired heart disease using human model systems.
@UniofOxford. Director of the Oxford Organoid Hub. Researching Inherited & acquired heart disease using human model systems.
Pinned
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
Reposted by Chris Toepfer
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
Assaying the myosin super-relaxed state across muscle types, cells and proteins for understanding muscle biology and use in drug discovery - Nature Protocols
The Mant-ATP assay is a simple and accessible means for rapid quantitative assessment of the ratio of super-relaxed myosin to disordered relaxed myosin. This protocol provides a standardized methodolo...
www.nature.com
December 1, 2025 at 4:21 PM
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
December 1, 2025 at 4:27 PM
We have today published a comprehensive set of protocols in
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
@natureportfolio.nature.com for assaying the myosin super-relaxed state across tissues, iPSC-CMs and molecules.
rdcu.be/eSysL
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
November 28, 2025 at 6:41 PM
Some good news, myself and @simoesfilipa.bsky.social are advertising for a post-doctoral researcher to join us at the Oxford Organoid hub: tinyurl.com/OOHJob
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
Come and join us to develop novel human organoid systems as part of the MRC/BHF CRE in advanced cardiac therapies.
A joy to present at the Oxford @thebhf.bsky.social Centre of Research Excellence annual symposium. Great discussions and a great opportunity to show some of the research happening around the Oxford Organoid Hub. @rdm.ox.ac.uk @simoesfilipa.bsky.social @idrm.ox.ac.uk
November 28, 2025 at 6:18 PM
A joy to present at the Oxford @thebhf.bsky.social Centre of Research Excellence annual symposium. Great discussions and a great opportunity to show some of the research happening around the Oxford Organoid Hub. @rdm.ox.ac.uk @simoesfilipa.bsky.social @idrm.ox.ac.uk