Tuuli Lappalainen
@tuuliel.bsky.social
Professor at KTH, NY Genome Center, SciLifeLab, working on functional genomics and human genetics.
Reposted by Tuuli Lappalainen
🧬 New preprint alert! After years of collaborative work across 52 datasets we are presenting eQTLGen phase 2: a genome-wide eQTL meta-analysis covering 43,301 blood samples: www.medrxiv.org/content/10.6... (1/8)
February 6, 2026 at 10:14 AM
🧬 New preprint alert! After years of collaborative work across 52 datasets we are presenting eQTLGen phase 2: a genome-wide eQTL meta-analysis covering 43,301 blood samples: www.medrxiv.org/content/10.6... (1/8)
Reposted by Tuuli Lappalainen
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
Reposted by Tuuli Lappalainen
The lesson for all the students out there is that science is a community project. Most of us make individually small contributions to this project. Success is measured at the collective level. Many of our professional (and personal) dysfunctions could be fixed by more fully embracing this view.
February 7, 2026 at 11:20 AM
The lesson for all the students out there is that science is a community project. Most of us make individually small contributions to this project. Success is measured at the collective level. Many of our professional (and personal) dysfunctions could be fixed by more fully embracing this view.
Reposted by Tuuli Lappalainen
Please share this with your network: Postdoctoral position available in my group.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Albert Einstein College of Medicine hiring Postdoctoral position studying functional non-coding variants in neurodevelopmental disorders, Bronx, New York City, USA c in New York City Metropolitan Area...
Posted 9:40:20 PM. A postdoctoral fellow position is open with 2 years of funding from the Simons Foundation Autism…See this and similar jobs on LinkedIn.
www.linkedin.com
February 5, 2026 at 10:47 PM
Please share this with your network: Postdoctoral position available in my group.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Reposted by Tuuli Lappalainen
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.
faculty-einstein.icims.com/jobs/17847/a...
faculty-einstein.icims.com/jobs/17847/a...
Albert Einstein College of Medicine | Medical Education | Biomedical Research
faculty-einstein.icims.com
February 5, 2026 at 10:14 PM
Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.
faculty-einstein.icims.com/jobs/17847/a...
faculty-einstein.icims.com/jobs/17847/a...
Reposted by Tuuli Lappalainen
I think it's best for everyone to understand that the unified class project of billionaires right now is to do to white collar workers what globalization and neoliberalism did to blue collar workers.
February 4, 2026 at 7:41 PM
I think it's best for everyone to understand that the unified class project of billionaires right now is to do to white collar workers what globalization and neoliberalism did to blue collar workers.
Reposted by Tuuli Lappalainen
I started offering career advice to two junior colleagues today in separate meetings, and both times I caught myself thinking that, if I'm honest, I don't have very good advice on navigating the current funding and job climate. I think it's important to say that no one does.
February 3, 2026 at 3:46 AM
I started offering career advice to two junior colleagues today in separate meetings, and both times I caught myself thinking that, if I'm honest, I don't have very good advice on navigating the current funding and job climate. I think it's important to say that no one does.
Reposted by Tuuli Lappalainen
Kohta paljastuu kaikille, että hyvinvointivaltio tukikin rakenteellisesti taloutta ja talouskasvua, jolloin sen romuttaminen oli onneton rakenteellinen uudistus negatiivisin pitkän aikavälin vaikutuksin. Kiitos!
#talous #politiikka #yhteiskunta
#talous #politiikka #yhteiskunta
February 3, 2026 at 6:20 AM
Kohta paljastuu kaikille, että hyvinvointivaltio tukikin rakenteellisesti taloutta ja talouskasvua, jolloin sen romuttaminen oli onneton rakenteellinen uudistus negatiivisin pitkän aikavälin vaikutuksin. Kiitos!
#talous #politiikka #yhteiskunta
#talous #politiikka #yhteiskunta
Reposted by Tuuli Lappalainen
Nature and Science journalists denied entry to event featuring NIH Director
I'm at the Willard Hotel where I've been denied entry and kicked out of the Reclaiming Science event with NIH director Bhattacharya & other top agency leaders.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
@jocelynkaiser.bsky.social and I registered for the event months ago yet were told capacity was full, even as they let in dozens of others.
January 31, 2026 at 2:50 AM
Nature and Science journalists denied entry to event featuring NIH Director
Reposted by Tuuli Lappalainen
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...
www.biorxiv.org
January 31, 2026 at 1:13 AM
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element www.biorxiv.org/content/10.6...
Reposted by Tuuli Lappalainen
Because of technical issues with the SciENcv website, NIH is extending a period of leniency accepting old format biosketches through May 2026 (see FAQ #5):
grants.nih.gov/faqs#/common...
grants.nih.gov/faqs#/common...
Frequently Asked Questions (FAQs) | Grants & Funding
grants.nih.gov
January 29, 2026 at 8:30 PM
Because of technical issues with the SciENcv website, NIH is extending a period of leniency accepting old format biosketches through May 2026 (see FAQ #5):
grants.nih.gov/faqs#/common...
grants.nih.gov/faqs#/common...
Reposted by Tuuli Lappalainen
RFKJr's principal accomplishment as the nation's health guardian.
January 28, 2026 at 4:08 PM
RFKJr's principal accomplishment as the nation's health guardian.
A want new mandatory course in school curricula worldwide: Everyday logistics in urban environments. Content: How to exit the subway. How to enter the subway. How to move in stairs. How to queue.
January 27, 2026 at 5:05 PM
A want new mandatory course in school curricula worldwide: Everyday logistics in urban environments. Content: How to exit the subway. How to enter the subway. How to move in stairs. How to queue.
Reposted by Tuuli Lappalainen
WHO removing Us Flag
January 23, 2026 at 9:45 PM
WHO removing Us Flag
Reposted by Tuuli Lappalainen
NEW | Wind and solar generated more power than fossil fuels in the EU for the FIRST time ever.
🌪️ and ☀️ made up a RECORD 30% of 🇪🇺 electricity, up from 20% just five years ago.
https://ember-energy.org/latest-insights/european-electricity-review-2026/
🌪️ and ☀️ made up a RECORD 30% of 🇪🇺 electricity, up from 20% just five years ago.
https://ember-energy.org/latest-insights/european-electricity-review-2026/
January 22, 2026 at 7:01 AM
NEW | Wind and solar generated more power than fossil fuels in the EU for the FIRST time ever.
🌪️ and ☀️ made up a RECORD 30% of 🇪🇺 electricity, up from 20% just five years ago.
https://ember-energy.org/latest-insights/european-electricity-review-2026/
🌪️ and ☀️ made up a RECORD 30% of 🇪🇺 electricity, up from 20% just five years ago.
https://ember-energy.org/latest-insights/european-electricity-review-2026/
Reposted by Tuuli Lappalainen
The interesting applications of AI are all, like, "we built an open framework that uses processors on recycled cell phones to identify and triangulate the location of rare bugs in tropical rainforests" while big tech is going "what if we burned down that rainforest to summarize your emails?"
Calling all the PhDs I know to make monumental annoyances of themselves (and honestly, who better)
January 21, 2026 at 9:42 PM
The interesting applications of AI are all, like, "we built an open framework that uses processors on recycled cell phones to identify and triangulate the location of rare bugs in tropical rainforests" while big tech is going "what if we burned down that rainforest to summarize your emails?"
Reposted by Tuuli Lappalainen
Lunchtime panel of faculty experts on Venezuela and oil politics in one of our larger event spaces on campus was standing room only today. Packed with students, faculty, community members. Makes me wonder why we aren’t doing teach-ins like this every week.
January 21, 2026 at 10:10 PM
Lunchtime panel of faculty experts on Venezuela and oil politics in one of our larger event spaces on campus was standing room only today. Packed with students, faculty, community members. Makes me wonder why we aren’t doing teach-ins like this every week.
Reposted by Tuuli Lappalainen
Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers.
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
US science after a year of Trump: what has been lost and what remains
A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.
www.nature.com
January 20, 2026 at 6:08 PM
Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers.
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
Reposted by Tuuli Lappalainen
I just woke up from a nap and somehow while I was asleep, everyone on the bus has figured out we are not going to the right place
January 20, 2026 at 1:57 AM
I just woke up from a nap and somehow while I was asleep, everyone on the bus has figured out we are not going to the right place
Reposted by Tuuli Lappalainen
New preprint on technologies to scale up CRISPR screens.
We use them to map 665,856 pairwise genetic perturbations and outline a path to comprehensive interaction mapping in human cells.
We also introduce an approach for cloning lentiviral libraries with billions of elements.
We use them to map 665,856 pairwise genetic perturbations and outline a path to comprehensive interaction mapping in human cells.
We also introduce an approach for cloning lentiviral libraries with billions of elements.
January 20, 2026 at 1:42 PM
New preprint on technologies to scale up CRISPR screens.
We use them to map 665,856 pairwise genetic perturbations and outline a path to comprehensive interaction mapping in human cells.
We also introduce an approach for cloning lentiviral libraries with billions of elements.
We use them to map 665,856 pairwise genetic perturbations and outline a path to comprehensive interaction mapping in human cells.
We also introduce an approach for cloning lentiviral libraries with billions of elements.
Reposted by Tuuli Lappalainen
SciLifeLab PULSE postdoc program focuses on innovative, fundamental, translational research. "The entrepreneurial track sparks the next generation of life-science ventures based on ground-breaking research at universities” says Kristian Sandberg. 🧪🌍
Apply today!
www.scilifelab.se/news/pulse-p...
Apply today!
www.scilifelab.se/news/pulse-p...
PULSE postdoc program advances training through academic and industry secondments
The SciLifeLab PULSE postdoc program, currently recruiting the second cohort of international talent to Swedish universities has two tracks: the academic and the entrepreneurial, industry supported…
buff.ly
January 20, 2026 at 9:22 AM
SciLifeLab PULSE postdoc program focuses on innovative, fundamental, translational research. "The entrepreneurial track sparks the next generation of life-science ventures based on ground-breaking research at universities” says Kristian Sandberg. 🧪🌍
Apply today!
www.scilifelab.se/news/pulse-p...
Apply today!
www.scilifelab.se/news/pulse-p...
Reposted by Tuuli Lappalainen
My specific experience is with NIH, but I’ll stand up and say it:
The people who work at NIH are together one of the great wonders of the world. US biomedical science, cancer cures, dementia research all are built on their talent and dedication.
The people who work at NIH are together one of the great wonders of the world. US biomedical science, cancer cures, dementia research all are built on their talent and dedication.
For some reason, very few people these days will stand up and say it, but: the US federal bureaucracy is one of the great wonders of the world, staffed with incredibly diligent people who do their jobs well and care deeply.
Trump's destruction of the federal apparaus was a historic crime.
Trump's destruction of the federal apparaus was a historic crime.
The Purged
Donald Trump’s destruction of the civil service is a tragedy not just for the roughly 300,000 workers who have been discarded, but for an entire nation.
www.theatlantic.com
January 18, 2026 at 7:29 PM
My specific experience is with NIH, but I’ll stand up and say it:
The people who work at NIH are together one of the great wonders of the world. US biomedical science, cancer cures, dementia research all are built on their talent and dedication.
The people who work at NIH are together one of the great wonders of the world. US biomedical science, cancer cures, dementia research all are built on their talent and dedication.
Reposted by Tuuli Lappalainen
1,000 PacBio genomes in a prospectively designed clinical utility study.
This was the biggest and most important study that made us go live in diagnostics.
Long-read genomes as a genetic first tier test across many rare diseases!
www.medrxiv.org/content/10.6...
This was the biggest and most important study that made us go live in diagnostics.
Long-read genomes as a genetic first tier test across many rare diseases!
www.medrxiv.org/content/10.6...
Clinical long-read genome sequencing for rare disease diagnostics
Background Diagnostic evaluation of rare genetic disorders continues to rely on multiple test modalities, despite the increasing use of short-read exome or genome sequencing as first-tier tests. Long-...
www.medrxiv.org
January 19, 2026 at 8:30 AM
1,000 PacBio genomes in a prospectively designed clinical utility study.
This was the biggest and most important study that made us go live in diagnostics.
Long-read genomes as a genetic first tier test across many rare diseases!
www.medrxiv.org/content/10.6...
This was the biggest and most important study that made us go live in diagnostics.
Long-read genomes as a genetic first tier test across many rare diseases!
www.medrxiv.org/content/10.6...
Reposted by Tuuli Lappalainen
A long, absolutely must-read article from Cory Doctorow: www.theguardian.com/us-news/ng-i...
AI companies will fail. We can salvage something from the wreckage | Cory Doctorow
AI is asbestos in the walls of our tech society, stuffed there by monopolists run amok. A serious fight against it must strike at its roots
www.theguardian.com
January 18, 2026 at 9:01 PM
A long, absolutely must-read article from Cory Doctorow: www.theguardian.com/us-news/ng-i...
Reposted by Tuuli Lappalainen
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 16, 2026 at 6:33 PM
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...