Florian Wimmers
@therealimmunecell.bsky.social
Emmy Noether Research Group Leader @University of Tübingen | ex StanfordMed
https://theWimmersLab.com
Fascinated by the human immune system, multi-omics + AI, and robots!
https://theWimmersLab.com
Fascinated by the human immune system, multi-omics + AI, and robots!
Warum reagieren Krebspatient:innen oft anders – und manchmal sogar besser – auf Impfungen?
Darüber durfte ich im Podcast „Der Code des Lebens“ sprechen. Ein herzliches Dankeschön an das Team für die Gelegenheit, meine Forschung zu Impfantworten, Organoiden und KI vorzustellen.
Darüber durfte ich im Podcast „Der Code des Lebens“ sprechen. Ein herzliches Dankeschön an das Team für die Gelegenheit, meine Forschung zu Impfantworten, Organoiden und KI vorzustellen.
January 7, 2026 at 10:55 AM
Warum reagieren Krebspatient:innen oft anders – und manchmal sogar besser – auf Impfungen?
Darüber durfte ich im Podcast „Der Code des Lebens“ sprechen. Ein herzliches Dankeschön an das Team für die Gelegenheit, meine Forschung zu Impfantworten, Organoiden und KI vorzustellen.
Darüber durfte ich im Podcast „Der Code des Lebens“ sprechen. Ein herzliches Dankeschön an das Team für die Gelegenheit, meine Forschung zu Impfantworten, Organoiden und KI vorzustellen.
Reposted by Florian Wimmers
🔬 Future of #Toxicology? Discover how #NAMs are reshaping safety—more predictive, more human-relevant.
📍 @unituebingen.bsky.social Tübingen
📅 March 24–26, 2026
📝 Submit by Nov 14, 2025
more infos: bit.ly/4nAHiNd
📍 @unituebingen.bsky.social Tübingen
📅 March 24–26, 2026
📝 Submit by Nov 14, 2025
more infos: bit.ly/4nAHiNd
November 3, 2025 at 8:23 AM
🔬 Future of #Toxicology? Discover how #NAMs are reshaping safety—more predictive, more human-relevant.
📍 @unituebingen.bsky.social Tübingen
📅 March 24–26, 2026
📝 Submit by Nov 14, 2025
more infos: bit.ly/4nAHiNd
📍 @unituebingen.bsky.social Tübingen
📅 March 24–26, 2026
📝 Submit by Nov 14, 2025
more infos: bit.ly/4nAHiNd
Reposted by Florian Wimmers
Vaccines have health benefits you didn’t even know about. Get your flu shots yearly, and shingles shots as soon as you are eligible.
Acute and chronic viral infections, including Herpes Zoster (Shingles), Hepatitis C, HIV, CMV, influenza, and SARS-CoV-2, are linked with a substantial increased risk of cardiovascular events, from a systematic review. Figure for SARS-CoV-2 below
newsroom.heart.org/news/some-ac...
newsroom.heart.org/news/some-ac...
October 29, 2025 at 1:44 PM
Vaccines have health benefits you didn’t even know about. Get your flu shots yearly, and shingles shots as soon as you are eligible.
Studying neutrophils is not easy. Exciting to see that they can acquire longterm changes associated with epigenetic reprogramming.
#Neutrophils are short lived cells, yet in ARDS display long term changes, with impaired neutrophil functions even after 6 months. How can they undergo long term reprogramming?
this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky
this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity - Nature Immunology
Walmsley and colleagues report that systemic hypoxia induces persistent loss of histone H3K4me3 marks and epigenetic reprogramming in neutrophil progenitors, resulting in long-term impairment of subse...
www.nature.com
October 28, 2025 at 12:12 PM
Studying neutrophils is not easy. Exciting to see that they can acquire longterm changes associated with epigenetic reprogramming.
Reposted by Florian Wimmers
🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...
Junior Group Leader for RNA-Biology, RNA-Technology or RNA-Medicine (f/m/d) - Würzburg (Stadt), Bayern (DE) job with Helmholtz-Institut für RNA-basierte Infektionsforschung (HIRI) | 12844907
#RNAexcellence Junior Group Leader Positions (f/m/d) Job advertisement no.: 089/2025 Starting date: As soon as possible. The con...
www.nature.com
October 27, 2025 at 9:55 PM
🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...
Reposted by Florian Wimmers
September 1, 2025 at 8:16 PM
Reposted by Florian Wimmers
🔬PhD position available!
Join our 🇨🇭🇮🇹 collaborative project on #Neuroimmunology and #ParkinsonsDisease — work with patient-derived samples and cutting-edge methods.
📄 Details: drive.google.com/file/d/1Znx_...
@syis-ecr.bsky.social @yefis-immunology.bsky.social
Join our 🇨🇭🇮🇹 collaborative project on #Neuroimmunology and #ParkinsonsDisease — work with patient-derived samples and cutting-edge methods.
📄 Details: drive.google.com/file/d/1Znx_...
@syis-ecr.bsky.social @yefis-immunology.bsky.social
PhD Position_Neuroimmunology.pdf
drive.google.com
July 30, 2025 at 10:44 AM
🔬PhD position available!
Join our 🇨🇭🇮🇹 collaborative project on #Neuroimmunology and #ParkinsonsDisease — work with patient-derived samples and cutting-edge methods.
📄 Details: drive.google.com/file/d/1Znx_...
@syis-ecr.bsky.social @yefis-immunology.bsky.social
Join our 🇨🇭🇮🇹 collaborative project on #Neuroimmunology and #ParkinsonsDisease — work with patient-derived samples and cutting-edge methods.
📄 Details: drive.google.com/file/d/1Znx_...
@syis-ecr.bsky.social @yefis-immunology.bsky.social
Postdoc Opening – Cancer & Immune Interactions
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.
🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)
Apply by Aug 25
www.nature.com/naturecareer...
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.
🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)
Apply by Aug 25
www.nature.com/naturecareer...
Postdoctoral Researcher: Cancer-Immune Interactions in Human Organoid Systems - Tübingen, Baden-Württemberg (DE) job with University of Tübingen | 12841595
We are seeking a highly motivated Postdoctoral Researcher to determine the impact of cancer on immune responses in human organoid systems.
www.nature.com
July 24, 2025 at 6:54 AM
Postdoc Opening – Cancer & Immune Interactions
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.
🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)
Apply by Aug 25
www.nature.com/naturecareer...
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.
🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)
Apply by Aug 25
www.nature.com/naturecareer...
Great meeting! The exchange with fellow Emmy-Noether-awardees is an extremely valuable feature that other early career grants lack! Thanks for making this possible @dfg.de
Rund 150 (!) aktuell und ehemalig Geförderte waren beim diesjährigen #EmmyNoether-Jahrestreffen - und es war wieder einmal lustig, produktiv, sonnig, kollaborativ, synergetisch, kommunikativ und noch viel mehr. 😊
Kurzer Bericht, mehr Impressionen & die Präsentationen zu den Talks:
fcld.ly/ent2025
Kurzer Bericht, mehr Impressionen & die Präsentationen zu den Talks:
fcld.ly/ent2025
July 17, 2025 at 9:38 AM
Great meeting! The exchange with fellow Emmy-Noether-awardees is an extremely valuable feature that other early career grants lack! Thanks for making this possible @dfg.de
Reposted by Florian Wimmers
𝗠𝗶𝗰𝗿𝗼𝗯𝗲𝘀: 𝗞𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿𝘀 𝗶𝗻 𝗵𝘂𝗺𝗮𝗻 𝗵𝗲𝗮𝗹𝘁𝗵
The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health.
On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.
The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health.
On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.
June 27, 2025 at 4:57 AM
𝗠𝗶𝗰𝗿𝗼𝗯𝗲𝘀: 𝗞𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿𝘀 𝗶𝗻 𝗵𝘂𝗺𝗮𝗻 𝗵𝗲𝗮𝗹𝘁𝗵
The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health.
On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.
The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health.
On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.
If you’re curious what we’ve been up to lately, check out this feature on our recent work in Attempto!
📢 Eine neue Ausgabe von ATTEMPTO! – der Zeitschrift für Forschung der Universität Tübingen - gibt es online und als Printmagazin. 🤗 Wir wünschen viel Lesevergnügen: www.uni-tuebingen.de/attempto
📷: Illustration: ChatGPT / DALL-E; Titelfoto: Valentin Marquardt, MockUp: pixpine
📷: Illustration: ChatGPT / DALL-E; Titelfoto: Valentin Marquardt, MockUp: pixpine
June 12, 2025 at 11:08 AM
If you’re curious what we’ve been up to lately, check out this feature on our recent work in Attempto!
Reposted by Florian Wimmers
Can vaccines heal cancer? In this episode, Prof. Juliane Walz reveals: "Very, very early in my life, I decided I wanted to do something with cancer and develop treatments for cancer." Discover personalized peptide vaccines in cancer immunotherapy 👉uni-tuebingen.de/en/269679 #Podcast #CancerResearch
February 14, 2025 at 1:12 PM
Can vaccines heal cancer? In this episode, Prof. Juliane Walz reveals: "Very, very early in my life, I decided I wanted to do something with cancer and develop treatments for cancer." Discover personalized peptide vaccines in cancer immunotherapy 👉uni-tuebingen.de/en/269679 #Podcast #CancerResearch
It was so much fun meeting all the wonderful new profs of BW and learning more about lab atomization and AI-assisted surgery. #TheNerdLänd
Great evening in Stuttgart celebrating that Baden-Württemberg is #TheNerdLänd with my #ERCStG colleagues @therealimmunecell.bsky.social and @mariuslemm.bsky.social
@unituebingen.bsky.social
@unituebingen.bsky.social
February 8, 2025 at 9:10 AM
It was so much fun meeting all the wonderful new profs of BW and learning more about lab atomization and AI-assisted surgery. #TheNerdLänd
Reposted by Florian Wimmers
🚨 Join the #EUROoCS digital lecture with Peter Loskill tomorrow, Jan 21, 5–6 PM CET!
Learn how #immunocompetent tissues enhance #OrganOnChip models for Immuno #Oncology, (cardio) #metabolic & #ophthalmology research! 🔬🧫
👉 Register at: bit.ly/EUROoCS-Lecture
@plosk.bsky.social
@3rcenter.bsky.social
Learn how #immunocompetent tissues enhance #OrganOnChip models for Immuno #Oncology, (cardio) #metabolic & #ophthalmology research! 🔬🧫
👉 Register at: bit.ly/EUROoCS-Lecture
@plosk.bsky.social
@3rcenter.bsky.social
January 20, 2025 at 10:47 AM
🚨 Join the #EUROoCS digital lecture with Peter Loskill tomorrow, Jan 21, 5–6 PM CET!
Learn how #immunocompetent tissues enhance #OrganOnChip models for Immuno #Oncology, (cardio) #metabolic & #ophthalmology research! 🔬🧫
👉 Register at: bit.ly/EUROoCS-Lecture
@plosk.bsky.social
@3rcenter.bsky.social
Learn how #immunocompetent tissues enhance #OrganOnChip models for Immuno #Oncology, (cardio) #metabolic & #ophthalmology research! 🔬🧫
👉 Register at: bit.ly/EUROoCS-Lecture
@plosk.bsky.social
@3rcenter.bsky.social
Nothing like walking into work and seeing this—the colors are pure magic!
January 14, 2025 at 7:08 AM
Nothing like walking into work and seeing this—the colors are pure magic!
Excited to see this paper out. Durability is the holy grail of vaccine design. 💉 Here, we made the unexpected discovery that megakaryocytes, the cells that produce wound-healing platelets, can support long lasting vaccine immunity! #BiologyIsWild! 🧬🔬 Glad I could be part of this wonderful team!
Our collaborators analyze multiple predictors of antibody response in #vaccines in humans.
@natureportfolio.bsky.social
Authors include: Bali Pulendran, Mark Mulligan, @tsanglab.bsky.social Steve Bosinger, @therealimmunecell.bsky.social
www.nature.com/articles/s41...
@natureportfolio.bsky.social
Authors include: Bali Pulendran, Mark Mulligan, @tsanglab.bsky.social Steve Bosinger, @therealimmunecell.bsky.social
www.nature.com/articles/s41...
System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans - Nature Immunology
Pulendran and colleagues define a molecular signature that can be used to predict the durability of antibody responses to vaccination and reveal important insights into the mechanisms by which vaccine...
www.nature.com
January 7, 2025 at 5:48 PM
Excited to see this paper out. Durability is the holy grail of vaccine design. 💉 Here, we made the unexpected discovery that megakaryocytes, the cells that produce wound-healing platelets, can support long lasting vaccine immunity! #BiologyIsWild! 🧬🔬 Glad I could be part of this wonderful team!
Reposted by Florian Wimmers
Reposted by Florian Wimmers
Brilliant work congrats to the authors!
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 12, 2024 at 9:29 AM
Brilliant work congrats to the authors!
Calling all bioinformatics experts: I’m considering incorporating LLMs (like ChatGPT) as coding assistants into a beginners class on omics analysis & applied bioinformatics. Are they a help or a crutch for early learners? What’s your take on the risks/benefits? #Bioinformatics #LLMs #CodingEducation
December 10, 2024 at 6:35 PM
Calling all bioinformatics experts: I’m considering incorporating LLMs (like ChatGPT) as coding assistants into a beginners class on omics analysis & applied bioinformatics. Are they a help or a crutch for early learners? What’s your take on the risks/benefits? #Bioinformatics #LLMs #CodingEducation
Reposted by Florian Wimmers
Der CMFI Nikolaus war an der Universität Tübingen unterwegs und hat für die Studierenden und Mitarbeitenden Schokonikoläuse auf dem gesamten Campus versteckt. Sein Versteckspiel haben wir für euch gefilmt. #Nikolaus
youtu.be/YK7FWOE_w_s?...
youtu.be/YK7FWOE_w_s?...
Der CMFI Nikolaus versteckt Geschenke an der Universität Tübingen
YouTube video by CMFI - Cluster of Excellence
youtu.be
December 6, 2024 at 6:50 AM
Der CMFI Nikolaus war an der Universität Tübingen unterwegs und hat für die Studierenden und Mitarbeitenden Schokonikoläuse auf dem gesamten Campus versteckt. Sein Versteckspiel haben wir für euch gefilmt. #Nikolaus
youtu.be/YK7FWOE_w_s?...
youtu.be/YK7FWOE_w_s?...
Reposted by Florian Wimmers
This is really horrific. These single cell reference atlases are widely used as is to train all kinds of models! This is one of the reasons I've constantly harping about uniform reprocessing & extremely careful QC of large atlases. 1/
scRNA-seq has revolutionized biology, but it’s not without challenges. We uncovered significant quality issues in widely used reference cell atlases like the Human Cell Atlas and Tabula Sapiens. Up to 85% of cells in some datasets are low-quality or misidentified!
2/8
2/8
December 4, 2024 at 7:06 AM
This is really horrific. These single cell reference atlases are widely used as is to train all kinds of models! This is one of the reasons I've constantly harping about uniform reprocessing & extremely careful QC of large atlases. 1/
Reposted by Florian Wimmers
The Immune Alliance Meeting in Nara, Japan. Bridging great scientific exchange and collegial friendship across countries. @dgfi_org @YI_dgfi #immunology
November 30, 2024 at 9:02 AM
The Immune Alliance Meeting in Nara, Japan. Bridging great scientific exchange and collegial friendship across countries. @dgfi_org @YI_dgfi #immunology
Fascinating findings: Immune system disruptions in cancer patients can persist over a decade post-treatment. We still know so little about the long-term impact of therapies on immunity.
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 30, 2024 at 12:44 AM
Fascinating findings: Immune system disruptions in cancer patients can persist over a decade post-treatment. We still know so little about the long-term impact of therapies on immunity.
Thrilled to delve into the world of #immunology 💉 and connect with brilliant colleagues in the truely exceptional setting of #Nara Park! 🇯🇵 Deers are roaming the conference venue! 🦌 🏯 #ImmuneAlliance #DGfI #JSI
November 29, 2024 at 6:08 AM
Thrilled to delve into the world of #immunology 💉 and connect with brilliant colleagues in the truely exceptional setting of #Nara Park! 🇯🇵 Deers are roaming the conference venue! 🦌 🏯 #ImmuneAlliance #DGfI #JSI
Thrilled to see this study! Three years ago, we uncovered an IRF/AP-1-driven epigenetic program boosting antiviral resistance after flu vaccination. Amazing to see similar myeloid plasticity and reduced inflammation emerging beyond influenza. Immunology never ceases to amaze! 😊
Great Spotlight by @virusesimmunity.bsky.social and #SashaTabachnikova on our recent publication in #Immunity, where we studied antiviral innate immune memory in alveolar macrophages in the context of respiratory viral infections!
www.cell.com/trends/immun...
www.cell.com/trends/immun...
SARS-CoV-2 reprograms murine alveolar macrophages to dampen flu
Innate immune cells that are epigenetically reprogrammed by infection can modify host
responses to subsequent infections. Lercher et al. have identified epigenetic reprogramming
of murine airway-resid...
www.cell.com
November 26, 2024 at 9:27 AM
Thrilled to see this study! Three years ago, we uncovered an IRF/AP-1-driven epigenetic program boosting antiviral resistance after flu vaccination. Amazing to see similar myeloid plasticity and reduced inflammation emerging beyond influenza. Immunology never ceases to amaze! 😊