mashreghilab.bsky.social
@mashreghilab.bsky.social
Paper rdcu.be/eyB5k shows how respiratory viruses including SARS‑CoV‑2 can awaken dormant breast cancer cells via IL‑6–driven inflammation and drive metastasis. Echoes our work rdcu.be/eyIFg COVID‑induced TGF‑β immunosuppression reactivates EBV in PASC, MIS-C
Respiratory viral infections awaken metastatic breast cancer cells in lungs
Nature - Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by...
rdcu.be
August 1, 2025 at 4:44 PM
Reposted
"Manche haben die Infektion nicht bemerkt. Wochen später haben die Kinder diese Entzündungsreaktion entwickelt. Auf den ersten Blick hat das mit SARS-2 nichts zu tun." @mashreghilab.bsky.social@drfzberlin.bsky.social
“Plötzlich gab es zehnmal mehr Fälle.”
Manche Kinder entwickeln nach einer leichten Corona-Infektion eine schwere Entzündungsreaktion: MIS-C, auch PIMS genannt. Lange Zeit war unklar, warum.
leibniz-lab-pandemic-preparedness.de
July 22, 2025 at 7:47 AM
Reposted
#EveryCellIsAnImmuneCell! Cineus, Hegazy &co show @natimmunol.nature.com that during #colitis ILCs produce IL22 which drives oncostatin M #OSM signaling in intestinal #epithelial cells recruiting immune cells, exacerbating inflammation & being essential for tumorigenesis & colorectal tumor growth!
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis - Nature Immunology
Hegazy and colleagues demonstrate that epithelial oncostatin M receptor expression drives gut inflammation and tumor formation.
www.nature.com
May 30, 2025 at 10:20 PM
top-tier talks on immunology of COVID-19 at the symposium of the European Federation of Immunological Societies (EFIS) ...

m.youtube.com/playlist?lis...
Symposium of EFIS on the occasion of 5 years of COVID-19 - 4 April 2025 - YouTube
The Reaction to SARS-CoV-2: An Immunological Retrospective Symposium of EFIS on the occasion of 5 years of COVID-19 Kaiserin-Friedrich Stiftung, Robert-Koch ...
m.youtube.com
May 28, 2025 at 11:08 AM
Reposted
We welcome you to the next Immune Alliance Seminar, this time with Keishi Fujio (Tokyo) and Ulf Panzer (Hamburg).

The lecture takes place on march 19, 2025, 9am (in Germany)/5pm (in Japan), via zoom. Everyone is welcome to join. Registration is free.

Register via www.dgfi.org/immune-alliance/
March 5, 2025 at 4:58 PM
Reposted
Join EFIS on 4 April for an encounter dedicated to exploring - from an immunological standpoint - the unresolved issues and misconceptions of COVID-19 vaccination five years after the WHO declaration of the pandemic.

Program:
www.efis.org/.../Reaction....

Register:
www.efis.org/events/efis-...
March 20, 2025 at 10:41 AM
Reposted
Nature research paper: TGFβ links EBV to multisystem inflammatory syndrome in children

https://go.nature.com/43HJ4pu
TGFβ links EBV to multisystem inflammatory syndrome in children - Nature
Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.
go.nature.com
March 17, 2025 at 11:43 AM
Reposted
Rätsel um PIMS-Erkrankungen bei Kindern gelöst#Corona#PIMS#Kindergesundheit
Rätsel um PIMS-Erkrankungen bei Kindern gelöst
Berliner Forschende haben die Ursache für das rätselhaften Entzündungssyndrom gefunden.
www.tagesschau.de
March 12, 2025 at 5:12 PM
Reposted
How does SARS-CoV-2 lead to the multisystem inflammatory syndrome in children, a rare, potentially fatal condition?
www.nature.com/articles/s41...
High levels of TGFβ interfere with the child's response to control Epstein Barr virus, leading to its reactivation and severe inflammation @nature.com
TGFβ links EBV to multisystem inflammatory syndrome in children - Nature
Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.
www.nature.com
March 12, 2025 at 4:39 PM
‼️ Cause of post-#COVID inflammatory shock in children identified: Reactivation of the Epstein-Barr virus appears to cause the rare condition #MISC. The findings, uncovered by a team from #CharitéBerlin & @drfzberlin.bsky.social, have now been published in @nature.com
www.charite.de/en/service/p...
Press reports: Charité – Universitätsmedizin Berlin
Press release of the Charité – Universitätsmedizin Berlin
www.charite.de
March 12, 2025 at 4:34 PM
Our latest study in @nature.com reveals how #TGFβ drives Epstein-Barr Virus (#EBV) reactivation in multisystem inflammatory syndrome in #children (#MISC, #PIMS) following #COVID19.
@drfzberlin.bsky.social @mashreghilab.bsky.social

🔗 Read here:https://www.nature.com/articles/s41586-025-08697-6
Nature
Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest ...
nature.com
March 12, 2025 at 4:18 PM
Reposted
Prof. Dr. Thomas Krieg is the new President of the Board of Trustees of the DRFZ, succeeding Prof. Dr. Elisabeth Märker-Hermann. Dr. med. Julia Rautenstrauch is elected Vice President of the Board of Trustees. www.drfz.de/en/neuigkeit...
March 10, 2025 at 12:19 PM
Reposted
#IUIS2025 is happening next year in Vienna, Austria, from August 17-22. Join us for a week of cutting-edge immunology, groundbreaking research, and global collaboration.
Early registration and abstract submissions are now OPEN at www.iuis2025.org! See you there! 🌍
November 24, 2024 at 11:58 PM
Reposted
Academic exchange between the University of Tottori in Japan and the DRFZ - contract recently signed: bit.ly/4aBmHmX
January 27, 2025 at 12:23 PM
Reposted
Dear friends of the DRFZ,

An eventful year is almost over.
We wish all colleagues and friends of the DRFZ a peaceful and relaxing holiday season.

We look forward to an exciting new year together in 2025!
December 20, 2024 at 9:42 AM
Bimodal single-cell RNA-seq data reveals four distinct modalities, uncovering genes tied to splicing, transcription & degradation rates.

academic.oup.com/nargab/artic...
Exploring transcription modalities from bimodal, single-cell RNA sequencing data
Abstract. There is a growing interest in generating bimodal, single-cell RNA sequencing (RNA-seq) data for studying biological pathways. These data are pre
academic.oup.com
December 20, 2024 at 11:58 AM
Reposted
ILC2 are a non-redundant source of IL-5 required for development and function of murine B1 cells
www.nature.com/articles/s41...
December 4, 2024 at 11:59 PM
The Immune Alliance Meeting in Nara, Japan. Bridging great scientific exchange and collegial friendship across countries. @dgfi_org @YI_dgfi #immunology
November 30, 2024 at 9:02 AM
Reposted
Dear Immunology aficionados, you like to hear some exciting short lectures about the latest immunological discoveries from prominent scientists? Then join the virtual ImmuneAlliance Seminar series! Every 3rd Wed each month. For the link: dgfi.org/immune-allia.... #dgfi #ydgfi
November 19, 2024 at 12:59 PM