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hipcproject.bsky.social
HIPC
@hipcproject.bsky.social
370 followers 63 following 130 posts
This collaborative #openscience data project probes immune systems. Funded by NIAID since 2010.
https://immunespace.org
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hipcproject.bsky.social
HIPC @hipcproject.bsky.social · Aug 6
Come get your curated #immune #assays from 1,000s of human subjects at our website
immunespace.org
🧪 #immunology #IDSky #ImmuneSky
immunespace.org/query/filters

giphy.com/gifs/Giflyti...
Analyze Lucky Charms GIF by Giflytics - Find & Share on GIPHY
Discover & share this Analyze Lucky Charms GIF by Giflytics with everyone you know. GIPHY is how you search, share, discover, and create GIFs.
giphy.com
Reposted by HIPC
lji.org
Congratulations to LJI Professor Alessandro Sette, Dr.Biol.Sci. (@settelab.bsky.social)!

The Procter Prize from Sigma Xi honors Dr. Sette's impact as an immune system researcher and a science communicator! bit.ly/3Jhqe0s #Immunology #science #health #medicine #SanDiego #STEM
LJI Professor Alessandro Sette receives William Procter Prize for Scientific Achievement
Prestigious prize recognizes Sette's accomplishments as a researcher and scientific communicator
bit.ly
August 14, 2025 at 3:15 PM
Reposted by HIPC
sesmalab.bsky.social
Looking forward to my visit!
ajdiazphd.bsky.social Dr. Arnaldo Díaz @ajdiazphd.bsky.social · Aug 18
Join us on Sept 18th as we welcome Dr. @sesmalab.bsky.social to our PROVIDES Seminar Series. Dr. Fernández-Sesma will lead a research seminar on Immune responses to dengue virus infection and vaccination. Don’t miss the opportunity to learn about her research efforts.
August 19, 2025 at 7:58 PM
hipcproject.bsky.social
Come get your curated #immune #assays from 1,000s of human subjects at our website
immunespace.org
🧪 #immunology #IDSky #ImmuneSky
immunespace.org/query/filters

giphy.com/gifs/Giflyti...
Analyze Lucky Charms GIF by Giflytics - Find & Share on GIPHY
Discover & share this Analyze Lucky Charms GIF by Giflytics with everyone you know. GIPHY is how you search, share, discover, and create GIFs.
giphy.com
August 6, 2025 at 10:32 PM
hipcproject.bsky.social
3 of our recent studies deal with risk for death in #COVID19.
Two from Frontiers of Medicine.
1. frontiersin.org/journals/med...
2. frontiersin.org/journals/med...
One from @jci-insight.bsky.social

pubmed.ncbi.nlm.nih.gov/40608426/
All part of the IMPACC project. Some collaborators on map.
Map of United States shows many contributors to covid19 study called IMPACC. Study was of hospitalized patients testing their immune responses.
August 4, 2025 at 10:40 PM
hipcproject.bsky.social
More insights from #IMPACC studies, including polymorphism that might protect in #covid19 in online publication.
Authors include: @skleinstein.bsky.social @bjoernpeters.bsky.social @sesmalab.bsky.social @vivianasimonlab.bsky.social @joanndarce.bsky.social ++ others
insight.jci.org/articles/vie...
Screen shot of paper entitled "MICBG4064A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury." From JCI Insight publication.
July 31, 2025 at 4:00 PM
hipcproject.bsky.social
Thanks @jschaenmanmd.bsky.social for your comments and sorry if we didn't tag every author. There were too many! #covid19 #treatment #vulnerable
jschaenmanmd.bsky.social Joanna Schaenman, MD, PhD @jschaenmanmd.bsky.social · Jul 29
Great to see this work be published, it has been such a wonderful opportunity to be involved with the #IMPACC network - these important findings re immune response to #COVID will be useful for future pandemics especially for vulnerable populations @ast-idcop.bsky.social @niaidnews.bsky.social
July 30, 2025 at 6:13 PM
Reposted by HIPC
jschaenmanmd.bsky.social
Great to see this work be published, it has been such a wonderful opportunity to be involved with the #IMPACC network - these important findings re immune response to #COVID will be useful for future pandemics especially for vulnerable populations @ast-idcop.bsky.social @niaidnews.bsky.social
July 29, 2025 at 10:28 PM
hipcproject.bsky.social
Our collaborators identify chief predictor of #covid19 severity + death. Many authors include members of #IMPACC network: @rrmsky.bsky.social @bjoernpeters.bsky.social @skleinstein.bsky.social @sesmalab.bsky.social
@joanndarce.bsky.social @droferlevy.bsky.social
www.frontiersin.org/journals/med...
Frontiers | Baseline predictors for 28-day COVID-19 severity and mortality among hospitalized patients: results from the IMPACC study
IntroductionThe coronavirus disease 2019 (COVID-19) pandemic threatened public health and placed a significant burden on medical resources. The Immunophenoty...
www.frontiersin.org
July 29, 2025 at 2:52 PM
Reposted by HIPC
therealimmunecell.bsky.social
Postdoc Opening – Cancer & Immune Interactions
We’re hiring! Fully funded position to explore next-gen vaccines using organ-on-chip tech.

🔬 Study tumor–immune crosstalk in multi-organ systems
🤝 Work with 6 labs (microfluidics, organoids, bioinfo)

Apply by Aug 25

www.nature.com/naturecareer...
Postdoctoral Researcher: Cancer-Immune Interactions in Human Organoid Systems - Tübingen, Baden-Württemberg (DE) job with University of Tübingen | 12841595
We are seeking a highly motivated Postdoctoral Researcher to determine the impact of cancer on immune responses in human organoid systems.
www.nature.com
July 24, 2025 at 6:54 AM
hipcproject.bsky.social
Our collaborators unpacked a CD16 #polymorphism linked to #severe #covid19
Authors include: @skleinstein.bsky.social @bjoernpeters.bsky.social @sesmalab.bsky.social
@vivianasimonlab.bsky.social
@joanndarce.bsky.social
IMPACC group
insight.jci.org/articles/vie...
JCI Insight - High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19
insight.jci.org
July 24, 2025 at 8:18 PM
Reposted by HIPC
profshanecrotty.bsky.social
Beyond flu, intranasal platforms are also being develop for a range of pathogens.

Understanding immune dynamics at the tissue site, and being able to directly measure them in humans, may dramatically improve development of vaccines that elicit robust protection against respiratory viruses.
July 21, 2025 at 2:48 PM
Reposted by HIPC
profshanecrotty.bsky.social
In our new study we show local B-cell immunity and durable memory following live-attenuated influenza intranasal vaccination of humans. We utilized minimally invasive swabbing of human upper airway, following seasonal intramuscular or nasal (FluMist) flu vaccinations
www.biorxiv.org/content/10.1...
Local B-cell immunity and durable memory following live-attenuated influenza intranasal vaccination of humans
Seasonal influenza vaccines are most frequently delivered as intramuscular inactivated vaccines which elicit systemic responses against the immunodominant hemagglutinin (HA) head domain. An intranasal...
www.biorxiv.org
July 21, 2025 at 2:48 PM
hipcproject.bsky.social
Our collaborator Eva Harris
+ others describe way to distinguish #westnile virus infection by anti-premembrane antibodies in Nicaraguan children.
WNV is difficult to distinguish from other flaviviruses in sera.

journals.asm.org/doi/10.1128/...
Identification of West Nile virus infection by anti-premembrane antibodies in Nicaraguan children prior to 2007–2009 | Microbiology Spectrum
Since its arrival to North America in 1999, West Nile virus (WNV) has caused multiple outbreaks in birds and humans, with thousands of human cases in the USA and Canada, whereas in Latin America, WNV ...
journals.asm.org
July 21, 2025 at 2:31 PM
Reposted by HIPC
krishnaswamylab.bsky.social
Good morning from Vancouver! 🌞⛰️ We’re at #ICML2025 presenting at GenBio + MAS. Come chat with us about machine learning in biology!

With @RobertXiangruTang, @ChenLiu, @DanqiLiao. Views like this make the science even sweeter.🧬🧠

#ML #ComputationalBiology #ICML #Vancouver
July 17, 2025 at 8:30 PM
hipcproject.bsky.social
Our lab door has a "data door" that lets you download for #free 1000+ assays measuring #immune response.
immunespace.org
July 18, 2025 at 4:04 PM
Reposted by HIPC
benaroyaresearch.bsky.social
(1/8): New findings published this week in @jama.com Pediatrics are reshaping how we understand severe childhood asthma — especially in urban, low-income communities. 🧵
Image of BRI’s Matthew C. Altman, MD, MPhil; headline reads: “Asthma Exacerbations in Children Caused by Multiple Molecular Pathways”
July 15, 2025 at 3:23 PM
hipcproject.bsky.social
Hello to #ASV2025 and be sure to use our #free #data
You can upload from immunespace.org
Including multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping + many computational tools. #virology
July 17, 2025 at 1:35 PM
hipcproject.bsky.social
Our collaborator Purvesh Katri, and others, discover a #signature of #immune health.

med.stanford.edu/news/all-new...

@stanfordimmunology.bsky.social
Immune ‘dysregulation’ present prior to infection predicts severe responses
Stanford Medicine-led research finds that a gene signature capturing immune health or dysfunction can forecast patient outcomes following subsequent viral or bacterial infections.
med.stanford.edu
July 9, 2025 at 7:50 PM
hipcproject.bsky.social
We are a network of 8 big members:
@lji.org @columbiamed.bsky.social @yalemedicine.bsky.social MIT @seattlechildrens.bsky.social
@stanfordimmunology.bsky.social
Icahn Mt. Sinai @benaroyaresearch.bsky.social
You can upload our #free data at immunespace.org
Image from 2020. 🧪 #ImmuneSky
Against a green background, a pattern of consecutive rings has small round faces or icons. Each represents an institution or person who is connected with the center image - Human Immunology Project Consortium. A gov't financed research project aimed at understanding the human immune system.
July 7, 2025 at 9:03 PM
hipcproject.bsky.social
Our collaborators @rgottardo.bsky.social Peter Sims and Ken Stuart (and others) develop tool ADTNorm, a method of helping noisy CITE-seq data to be "normalized"
#antibody
#ImmuneSky

nature.com/articles/s41...

#CITEseq #SingleCell #ADTNorm
ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications
Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...
nature.com
July 2, 2025 at 5:29 PM
Reposted by HIPC
rgottardo.bsky.social
🧬 New paper out!
🔗 www.nature.com/articles/s41...

Frustrated by noisy CITE-seq data?
ADTNorm helps normalize it and introduces a staining index to assess antibody quality.

Great work by former postdoc Ye Zheng. Supported by @hipcproject.bsky.social

#CITEseq #SingleCell #ADTNorm
ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets - Nature Communications
Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing ...
www.nature.com
July 1, 2025 at 1:49 PM
Reposted by HIPC
rrmsky.bsky.social
Well annotated, curated, multiparameter FREE #immunology data, folks!
hipcproject.bsky.social HIPC @hipcproject.bsky.social · Jun 30
Our project spans 8+ institutions, with human cohorts studied with multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping of leukocyte subsets + many computational methods.
Get our #data for your own investigations.
#ImmuneSky #IDsky
immunespace.org
Page shows information about Human Immunology Project Consortium and the data from 174 studies, 52 diseases. https://immunespace.org
July 1, 2025 at 3:23 PM
hipcproject.bsky.social
Very glad to see our own collaborator @virusesimmunity.bsky.social honored among all of these. #science #immunology #virology #IDSky
lucyburns.bsky.social Lucy Burns @lucyburns.bsky.social · Jun 30
Every 4th of July, Carnegie Corporation of New York celebrates remarkable Americans — all naturalized citizens — who have enriched and strengthened our democracy through their actions and contributions.

Originating from 16 countries, here is the Carnegie 2025 Class of Great Immigrants:
2025 Great Immigrants | Carnegie Corporation of New York
www.carnegie.org
June 30, 2025 at 5:37 PM
hipcproject.bsky.social
Our project spans 8+ institutions, with human cohorts studied with multiplex transcriptional, #cytokine, and #proteomic assays; multiparameter #phenotyping of leukocyte subsets + many computational methods.
Get our #data for your own investigations.
#ImmuneSky #IDsky
immunespace.org
Page shows information about Human Immunology Project Consortium and the data from 174 studies, 52 diseases. https://immunespace.org
June 30, 2025 at 5:26 PM
hipcproject.bsky.social
Our collaborator Purvesh Khatri writes in preprint on new tool for #single-cell analysis called scMetaIntegrator.
The method provides robust effect size estimates and reproducible p-values.
#ImmuneSky
@stanfordimmunology.bsky.social
@biorxivpreprint.bsky.social
www.biorxiv.org/content/10.1...
June 23, 2025 at 2:55 PM