Adrian Liston
@labliston.bsky.social
Professor of Pathology at the University of Cambridge. Equalities Fellow, Welfare Tutor and Director-of-Studies at St Catharine's College. Educator, scientist, immunologist, daddy. Founder and CSO of Aila Biotech Ltd.
Pinned
Adrian Liston
@labliston.bsky.social
· Oct 28
Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.
Want to get a tough sample, like lung, looking like this? Read more!
www.biorxiv.org/content/10.1...
Want to get a tough sample, like lung, looking like this? Read more!
www.biorxiv.org/content/10.1...
Not the worst explanation I’ve heard for fever
December 26, 2025 at 8:22 PM
Not the worst explanation I’ve heard for fever
I have little time for LLMs for the same reason I have little time for liars. Having to double-check every item is exhausting. I’d rather not bother.
suspect a big reason why many academics and others who work in areas where getting facts RIGHT is key are disinterested in using LLMs for research:
they’ve tried it, they keep noticing major errors in output, and they conclude that having to verify all that doesn’t actually save them time.
they’ve tried it, they keep noticing major errors in output, and they conclude that having to verify all that doesn’t actually save them time.
December 21, 2025 at 10:15 PM
I have little time for LLMs for the same reason I have little time for liars. Having to double-check every item is exhausting. I’d rather not bother.
Reposted by Adrian Liston
"Range extender mediates long-distance
enhancer activity" by @evgenykvon.bsky.social 's team, led by @gracebower.bsky.social is one of my papers of the year. Discovery of a new class of cis-regulatory elements that modulate the regulatory activity and reach of enhancers.
doi.org/10.1038/s415...
enhancer activity" by @evgenykvon.bsky.social 's team, led by @gracebower.bsky.social is one of my papers of the year. Discovery of a new class of cis-regulatory elements that modulate the regulatory activity and reach of enhancers.
doi.org/10.1038/s415...
December 21, 2025 at 10:08 PM
"Range extender mediates long-distance
enhancer activity" by @evgenykvon.bsky.social 's team, led by @gracebower.bsky.social is one of my papers of the year. Discovery of a new class of cis-regulatory elements that modulate the regulatory activity and reach of enhancers.
doi.org/10.1038/s415...
enhancer activity" by @evgenykvon.bsky.social 's team, led by @gracebower.bsky.social is one of my papers of the year. Discovery of a new class of cis-regulatory elements that modulate the regulatory activity and reach of enhancers.
doi.org/10.1038/s415...
Reposted by Adrian Liston
My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
December 18, 2025 at 8:36 AM
My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
Reposted by Adrian Liston
I've been successfully using Burton's buffers with dawn and no Triton for staining an endosomally localized membrane protein.
December 17, 2025 at 5:43 PM
I've been successfully using Burton's buffers with dawn and no Triton for staining an endosomally localized membrane protein.
Reposted by Adrian Liston
I could not recommend this more strongly! A really unique opportunity to join a top immunology lab in Cambridge, doing innovative science. A great PI to work with!
We are hiring! 🙌
#Postdoc position in computational biology at the forefront of human T cell immunology at @Cambridge_Uni. 👇
cam.ac.uk/jobs/researc...
Unravel the secrets of human #tissue immunity in health and disease with multi-modal single-cell genomic datasets.
#ERCCoG
#Postdoc position in computational biology at the forefront of human T cell immunology at @Cambridge_Uni. 👇
cam.ac.uk/jobs/researc...
Unravel the secrets of human #tissue immunity in health and disease with multi-modal single-cell genomic datasets.
#ERCCoG
December 15, 2025 at 8:27 PM
I could not recommend this more strongly! A really unique opportunity to join a top immunology lab in Cambridge, doing innovative science. A great PI to work with!
I could not recommend this more strongly! A really unique opportunity to join a top immunology lab in Cambridge, doing innovative science. A great PI to work with!
We are hiring! 🙌
#Postdoc position in computational biology at the forefront of human T cell immunology at @Cambridge_Uni. 👇
cam.ac.uk/jobs/researc...
Unravel the secrets of human #tissue immunity in health and disease with multi-modal single-cell genomic datasets.
#ERCCoG
#Postdoc position in computational biology at the forefront of human T cell immunology at @Cambridge_Uni. 👇
cam.ac.uk/jobs/researc...
Unravel the secrets of human #tissue immunity in health and disease with multi-modal single-cell genomic datasets.
#ERCCoG
December 15, 2025 at 8:27 PM
I could not recommend this more strongly! A really unique opportunity to join a top immunology lab in Cambridge, doing innovative science. A great PI to work with!
Traffic jams are brutal this time of the year in Cambridge
December 15, 2025 at 3:26 PM
Traffic jams are brutal this time of the year in Cambridge
I feel like I've been doing a lot of presentations this year. Just added it up - 38 scientific seminars in 11 countries, plus 21 career development or research culture workshops, plus 12 undergraduate lectures, plus 2 public engagement presentations. More than one a week!
December 14, 2025 at 10:22 AM
I feel like I've been doing a lot of presentations this year. Just added it up - 38 scientific seminars in 11 countries, plus 21 career development or research culture workshops, plus 12 undergraduate lectures, plus 2 public engagement presentations. More than one a week!
Reposted by Adrian Liston
Our latest article celebrates some of our alumni and Fellows writing to inform and entertain children and young adults, including books written by joannechocolat.bsky.social, labliston.bsky.social and many others! Read more: www.caths.cam.ac.uk/writing-for-...
Writing for children and young adults
www.caths.cam.ac.uk
December 10, 2025 at 10:47 AM
Our latest article celebrates some of our alumni and Fellows writing to inform and entertain children and young adults, including books written by joannechocolat.bsky.social, labliston.bsky.social and many others! Read more: www.caths.cam.ac.uk/writing-for-...
Reposted by Adrian Liston
In our latest editorial, @labliston.bsky.social celebrates the perseverance behind the 2025 #NobelPrize in Physiology or Medicine. Learn how regulatory T cells act as the immune system's 'brakes', and how immunology and genetics came together to uncover these elusive cells.
An education in tolerance: the 2025 Nobel Prize in Physiology or Medicine
Summary: The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi to honour the research leading up to the discovery of the regulatory T…
journals.biologists.com
December 9, 2025 at 12:01 PM
In our latest editorial, @labliston.bsky.social celebrates the perseverance behind the 2025 #NobelPrize in Physiology or Medicine. Learn how regulatory T cells act as the immune system's 'brakes', and how immunology and genetics came together to uncover these elusive cells.
Reposted by Adrian Liston
Catz Fellow Prof. Adrian Liston (2023) & colleagues have uncovered major differences in one type of white blood cell in people living with #Alzheimers disease – new evidence about how this disease progresses & could be treated:
www.caths.cam.ac.uk/... @labliston.bsky.social @campathology.bsky.social
www.caths.cam.ac.uk/... @labliston.bsky.social @campathology.bsky.social
AI uncovers immune defect in Alzheimer’s disease
An international team of scientists led by a St Catharine’s Fellow has successfully harnessed artificial intelligence (AI) to uncover a defect in the immune system of people living with Alzheimer’s disease (AD) – providing new evidence about how this poorly-understood disease progresses and how it could be treated.
www.caths.cam.ac.uk
December 7, 2025 at 9:55 AM
Catz Fellow Prof. Adrian Liston (2023) & colleagues have uncovered major differences in one type of white blood cell in people living with #Alzheimers disease – new evidence about how this disease progresses & could be treated:
www.caths.cam.ac.uk/... @labliston.bsky.social @campathology.bsky.social
www.caths.cam.ac.uk/... @labliston.bsky.social @campathology.bsky.social
Reposted by Adrian Liston
Day 4 and the final day of the BSI saw a fantastic talk from @labliston.bsky.social about Tregs in the brain and an excellent session devoted to “Barriers, bugs, and breakdowns” - right up our street! Thank you to all organisers and presenters @britsocimm.bsky.social for a great week in Liverpool🫶
December 6, 2025 at 6:30 PM
Day 4 and the final day of the BSI saw a fantastic talk from @labliston.bsky.social about Tregs in the brain and an excellent session devoted to “Barriers, bugs, and breakdowns” - right up our street! Thank you to all organisers and presenters @britsocimm.bsky.social for a great week in Liverpool🫶
I am torn on this.
Yes, bullying is a major problem in UK academia, with little appetite of leadership to address it.
*But* to boil research culture down to a REF returnable metric, we need good metrics of research culture. Just creating tick-boxes that reward the most cynical players won't help.
Yes, bullying is a major problem in UK academia, with little appetite of leadership to address it.
*But* to boil research culture down to a REF returnable metric, we need good metrics of research culture. Just creating tick-boxes that reward the most cynical players won't help.
Don’t downplay problems of bullying and harassment in academia
The United Kingdom, like all countries, must prioritize a supportive research culture as an essential ingredient in research excellence.
www.nature.com
December 4, 2025 at 6:05 PM
I am torn on this.
Yes, bullying is a major problem in UK academia, with little appetite of leadership to address it.
*But* to boil research culture down to a REF returnable metric, we need good metrics of research culture. Just creating tick-boxes that reward the most cynical players won't help.
Yes, bullying is a major problem in UK academia, with little appetite of leadership to address it.
*But* to boil research culture down to a REF returnable metric, we need good metrics of research culture. Just creating tick-boxes that reward the most cynical players won't help.
Reposted by Adrian Liston
Beautiful talk by Matt Hepworth, so many exciting things happening at barrier surfaces. @hepworth-lab.bsky.social #BSI2025 @britsocimm.bsky.social @lydiabeckeriii.bsky.social
December 4, 2025 at 3:18 PM
Beautiful talk by Matt Hepworth, so many exciting things happening at barrier surfaces. @hepworth-lab.bsky.social #BSI2025 @britsocimm.bsky.social @lydiabeckeriii.bsky.social
Reposted by Adrian Liston
Fantastic talk by @labliston.bsky.social at #BSI25! Incredible prospects for IL-2 gene therapy and fascinating tools for tracing CRISPR knockouts. Brilliant! @britsocimm.bsky.social
December 4, 2025 at 10:06 AM
Fantastic talk by @labliston.bsky.social at #BSI25! Incredible prospects for IL-2 gene therapy and fascinating tools for tracing CRISPR knockouts. Brilliant! @britsocimm.bsky.social
Reposted by Adrian Liston
#BSI25 Neuro-immune crosstalk stellar talks by @labliston.bsky.social, Henrique Veiga Fernandes @champalimaudr.bsky.social & Menna Clatworthy @medcambridge.bsky.social/ @mrclmb.bsky.social
December 4, 2025 at 10:15 AM
#BSI25 Neuro-immune crosstalk stellar talks by @labliston.bsky.social, Henrique Veiga Fernandes @champalimaudr.bsky.social & Menna Clatworthy @medcambridge.bsky.social/ @mrclmb.bsky.social
Reposted by Adrian Liston
Very cool talk on Tips and Tricks on Spectral Flow Cytometry by Dr. Oliver Burton (@labliston.bsky.social) in the ThemeNight of the Flow Cytometry Core Facility of the @unibonn.bsky.social!
December 1, 2025 at 4:51 PM
Very cool talk on Tips and Tricks on Spectral Flow Cytometry by Dr. Oliver Burton (@labliston.bsky.social) in the ThemeNight of the Flow Cytometry Core Facility of the @unibonn.bsky.social!
My first Cambridge graduation, becoming Doctoris in Scientiis
November 29, 2025 at 2:44 PM
My first Cambridge graduation, becoming Doctoris in Scientiis
Reposted by Adrian Liston
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
A systems immunology analysis of Alzheimer's disease reveals an age‐ and environmental exposure‐independent disturbance in B cell maturation
INTRODUCTION Alzheimer's disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal mode...
alz-journals.onlinelibrary.wiley.com
November 26, 2025 at 12:02 PM
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Adrian Liston
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
A systems immunology analysis of Alzheimer's disease reveals an age‐ and environmental exposure‐independent disturbance in B cell maturation
INTRODUCTION Alzheimer's disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal mode...
alz-journals.onlinelibrary.wiley.com
November 26, 2025 at 2:02 PM
Reposted by Adrian Liston
Clues about aetiology of Alzheimer’s from an immune system perspective
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
A systems immunology analysis of Alzheimer's disease reveals an age‐ and environmental exposure‐independent disturbance in B cell maturation
INTRODUCTION Alzheimer's disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal mode...
alz-journals.onlinelibrary.wiley.com
November 26, 2025 at 12:20 PM
Clues about aetiology of Alzheimer’s from an immune system perspective
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
A systems immunology analysis of Alzheimer's disease reveals an age‐ and environmental exposure‐independent disturbance in B cell maturation
INTRODUCTION Alzheimer's disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal mode...
alz-journals.onlinelibrary.wiley.com
November 26, 2025 at 12:02 PM
Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social!
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...