Banoo Malik🇨🇦
@banoomalik.bsky.social
Origin of meiosis. (#meiosis4eva) Opinions are my own and not my employers.
Reposted by Banoo Malik🇨🇦
New update for the gbdraw web app!🚀
You can now display gene labels ONLY on the first genome in the linear diagram. Just select "First" in the "Label layout" option.
Try it out here👉: gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology #microbiology #streamlit
You can now display gene labels ONLY on the first genome in the linear diagram. Just select "First" in the "Label layout" option.
Try it out here👉: gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology #microbiology #streamlit
November 24, 2025 at 2:06 PM
New update for the gbdraw web app!🚀
You can now display gene labels ONLY on the first genome in the linear diagram. Just select "First" in the "Label layout" option.
Try it out here👉: gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology #microbiology #streamlit
You can now display gene labels ONLY on the first genome in the linear diagram. Just select "First" in the "Label layout" option.
Try it out here👉: gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology #microbiology #streamlit
Reposted by Banoo Malik🇨🇦
Reposted by Banoo Malik🇨🇦
In a potentially dramatic change to how it chooses what science to fund, NIH is ending a long-running practice at many of its institutes of establishing, and making public, a threshold peer-review score needed for a grant application’s approval. https://scim.ag/48ck2zu
NIH shake-up to grant decision-making draws concerns of political meddling
Policy drops “paylines” based on peer-review scores and requires geography and other factors to guide approvals
scim.ag
November 25, 2025 at 3:18 PM
In a potentially dramatic change to how it chooses what science to fund, NIH is ending a long-running practice at many of its institutes of establishing, and making public, a threshold peer-review score needed for a grant application’s approval. https://scim.ag/48ck2zu
Reposted by Banoo Malik🇨🇦
Science People: We at NSF are still recovering/catching up/getting our lives together. But the agency posted these FAQs about post-shutdown resumption of operations which might answer a lot of Qs for you: www.nsf.gov/resumption-o...
Resumption of Operations at NSF
Information for NSF staff and the research community regarding the agency's resumption of operations after a lapse in appropriations.
www.nsf.gov
November 18, 2025 at 6:08 PM
Science People: We at NSF are still recovering/catching up/getting our lives together. But the agency posted these FAQs about post-shutdown resumption of operations which might answer a lot of Qs for you: www.nsf.gov/resumption-o...
Reposted by Banoo Malik🇨🇦
In AIR-BORNE, I wrote about the reluctance many scientists had to acknowledge Covid can float to new hosts. Now it looks like something similar may be happening with bird flu, which may be blowing from farm to farm. Story in @propublica.org www.propublica.org/article/bird...
What the U.S. Government Is Dismissing That Could Seed a Bird Flu Pandemic
Egg producers suspect bird flu is traveling through the air. After a disastrous Midwestern outbreak early this year, we tested that theory and found that where the wind blew, the virus followed. Vacci...
www.propublica.org
November 19, 2025 at 1:00 AM
In AIR-BORNE, I wrote about the reluctance many scientists had to acknowledge Covid can float to new hosts. Now it looks like something similar may be happening with bird flu, which may be blowing from farm to farm. Story in @propublica.org www.propublica.org/article/bird...
Reposted by Banoo Malik🇨🇦
I will never forget having to edit Jamal’s final, posthumous piece for the Washington Post, after he was murdered.
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
Opinion | Jamal Khashoggi: What the Arab world needs most is free expression
The Arab world needs a modern version of the old transnational media so citizens can be informed about global events.
www.washingtonpost.com
November 18, 2025 at 6:48 PM
I will never forget having to edit Jamal’s final, posthumous piece for the Washington Post, after he was murdered.
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
Reposted by Banoo Malik🇨🇦
I’ve released a tool to sketch and edit phylogenetic trees!
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
PhyloWeaver – Interactive phylogenetic tree editor
Edit and visualize phylogenetic trees directly in your browser. PhyloWeaver lets you interactively rearrange tree topologies and export high-quality figures for publications and presentations.
yawak.jp
November 18, 2025 at 1:59 AM
I’ve released a tool to sketch and edit phylogenetic trees!
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
yawak.jp/PhyloWeaver/
Load a Newick file and intuitively add/remove/resize branches.
Useful for quick conceptual trees, extracting subtrees, or turning ideas into Newick.
Reposted by Banoo Malik🇨🇦
Join Drs. Carlos del Rio & D. Jane Hata on Dec. 11, 3 p.m. ET to discuss diagnosing fever in a returning traveler. Includes cases + insights on diagnostics & lab workflows. CE credits available! Sponsor: @biomerieux.com.
Register for free: asm.social/2GS
#ASMClinMicro
Register for free: asm.social/2GS
#ASMClinMicro
Diagnosing Fever in Returning Travelers
Explore best practices for diagnosing fever in returning travelers: standard tests, new tools and laboratory workflow tips in this webinar.
asm.social
November 17, 2025 at 7:16 PM
Join Drs. Carlos del Rio & D. Jane Hata on Dec. 11, 3 p.m. ET to discuss diagnosing fever in a returning traveler. Includes cases + insights on diagnostics & lab workflows. CE credits available! Sponsor: @biomerieux.com.
Register for free: asm.social/2GS
#ASMClinMicro
Register for free: asm.social/2GS
#ASMClinMicro
Reposted by Banoo Malik🇨🇦
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 9:55 PM
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Reposted by Banoo Malik🇨🇦
Daily reminder that you are a better writer and researcher than any generative AI platform around. Your skills are worthy and it takes far more time to clean-up and fact-check the mess some chatbot spits out than to just do it yourself 😘
November 17, 2025 at 10:22 PM
Daily reminder that you are a better writer and researcher than any generative AI platform around. Your skills are worthy and it takes far more time to clean-up and fact-check the mess some chatbot spits out than to just do it yourself 😘
Reposted by Banoo Malik🇨🇦
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 10:25 PM
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
Reposted by Banoo Malik🇨🇦
Delighted to see our study finally out in "print". Thanks to all the (many) contributors, collaborators and reviewers!
Mismatch repair disturbs meiotic crossover control in S. cerevisiae academic.oup.com/nar/article/...
Mismatch repair disturbs meiotic crossover control in S. cerevisiae academic.oup.com/nar/article/...
Mismatch repair disturbs meiotic crossover control in S. cerevisiae
Abstract. Crossover formation during meiosis generates genetic diversity. In many species most crossovers display interference, meaning they are spaced mor
academic.oup.com
November 13, 2025 at 8:40 PM
Delighted to see our study finally out in "print". Thanks to all the (many) contributors, collaborators and reviewers!
Mismatch repair disturbs meiotic crossover control in S. cerevisiae academic.oup.com/nar/article/...
Mismatch repair disturbs meiotic crossover control in S. cerevisiae academic.oup.com/nar/article/...
Reposted by Banoo Malik🇨🇦
The main project of my postdoc with @spo11rulz.bsky.social is now available on bioRxiv! By systematically integrating structural information with molecular evolution analyses, we gained new fascinating insights into the evolution of key meiotic recombination proteins: www.biorxiv.org/content/10.1...
www.biorxiv.org
November 14, 2025 at 10:10 AM
The main project of my postdoc with @spo11rulz.bsky.social is now available on bioRxiv! By systematically integrating structural information with molecular evolution analyses, we gained new fascinating insights into the evolution of key meiotic recombination proteins: www.biorxiv.org/content/10.1...
Reposted by Banoo Malik🇨🇦
Reposted by Banoo Malik🇨🇦
Reposted by Banoo Malik🇨🇦
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
November 7, 2025 at 11:02 AM
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
Reposted by Banoo Malik🇨🇦
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Reposted by Banoo Malik🇨🇦
A new computational method called FluWarning identifies divergent viral sequences to detect the early spread of zoonotic #viruses.
Early detection of viral spread is a crucial aspect of mitigation strategies. Learn more in #ScienceAdvances: https://scim.ag/3L7pvj4
Early detection of viral spread is a crucial aspect of mitigation strategies. Learn more in #ScienceAdvances: https://scim.ag/3L7pvj4
Lightweight multiscale early warning system for influenza A spillovers
Early detection of zoonoses using a few viral sequences is critical for the timely implementation of mitigation strategies.
scim.ag
October 29, 2025 at 5:45 PM
A new computational method called FluWarning identifies divergent viral sequences to detect the early spread of zoonotic #viruses.
Early detection of viral spread is a crucial aspect of mitigation strategies. Learn more in #ScienceAdvances: https://scim.ag/3L7pvj4
Early detection of viral spread is a crucial aspect of mitigation strategies. Learn more in #ScienceAdvances: https://scim.ag/3L7pvj4
Reposted by Banoo Malik🇨🇦
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model
go.nature.com/4qvCQly
go.nature.com/4qvCQly
Open-source protein structure AI aims to match AlphaFold
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
go.nature.com
October 29, 2025 at 10:01 AM
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model
go.nature.com/4qvCQly
go.nature.com/4qvCQly
Reposted by Banoo Malik🇨🇦
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by Banoo Malik🇨🇦
🚀gbdraw v0.7.0 is out!
- Feature overlap resolution
- Gradated BLAST hit ribbons
- Ruler-style scale
- Top/bottom legend placement
- Optimized defaults (for small genomes)
Try out: 👉 gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology
- Feature overlap resolution
- Gradated BLAST hit ribbons
- Ruler-style scale
- Top/bottom legend placement
- Optimized defaults (for small genomes)
Try out: 👉 gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology
October 26, 2025 at 1:34 PM
🚀gbdraw v0.7.0 is out!
- Feature overlap resolution
- Gradated BLAST hit ribbons
- Ruler-style scale
- Top/bottom legend placement
- Optimized defaults (for small genomes)
Try out: 👉 gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology
- Feature overlap resolution
- Gradated BLAST hit ribbons
- Ruler-style scale
- Top/bottom legend placement
- Optimized defaults (for small genomes)
Try out: 👉 gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology
Reposted by Banoo Malik🇨🇦
"Our findings uncovered a species survival strategy in which telomerase RNA extends telomeres for the next generation by hitchhiking on introns of germline-expressed genes." 🤯
#Celegans 🧪
#Celegans 🧪
Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes
Telomerase is a ribonucleoprotein complex that elongates telomeric DNA, ensuring germline immortality. In this study, we identified the Caenorhabditis elegans telomerase RNA component 1 (terc-1), as t...
www.science.org
October 23, 2025 at 10:16 PM
"Our findings uncovered a species survival strategy in which telomerase RNA extends telomeres for the next generation by hitchhiking on introns of germline-expressed genes." 🤯
#Celegans 🧪
#Celegans 🧪
Reposted by Banoo Malik🇨🇦
This is a really interesting story. Microsporidia have genome architecture as no other creatures! Congrats @amjadkhalaf.bsky.social
#Microsporidia are #parasites of growing importance. @amjadkhalaf.bsky.social @mblaxter.bsky.social @marakat.bsky.social &co present 40 new genomes from #DarwinTreeofLife sequencing of their arthropod hosts, revealing insights into #tetraploidy & #reproduction @plosbiology.org 🧪 plos.io/48HsAQJ
October 22, 2025 at 4:45 PM
This is a really interesting story. Microsporidia have genome architecture as no other creatures! Congrats @amjadkhalaf.bsky.social
Reposted by Banoo Malik🇨🇦
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Staff Scientist
About EMBL-EBI EMBL’s European Bioinformatics Institute is a data powerhouse, utilised on a global scale to advance scientific discovery through bioinformatics and solutions to some of the world’s mos...
embl.wd103.myworkdayjobs.com
October 10, 2025 at 7:30 AM
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Banoo Malik🇨🇦
Our @narjournal.bsky.social manuscript is out! It explores the growth of the GTDB (gtdb.ecogenomic.org) since its inception, as well as updates to the website, methodology, policies, and major taxonomic and nomenclatural changes over the past three years.
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
GTDB release 10: a complete and systematic taxonomy for 715 230 bacterial and 17 245 archaeal genomes
Abstract. The Genome Taxonomy Database (GTDB; https://gtdb.ecogenomic.org) provides a phylogenetically consistent and rank normalized genome-based taxonomy
academic.oup.com
October 22, 2025 at 2:20 PM
Our @narjournal.bsky.social manuscript is out! It explores the growth of the GTDB (gtdb.ecogenomic.org) since its inception, as well as updates to the website, methodology, policies, and major taxonomic and nomenclatural changes over the past three years.
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...