Christian Zierhut
@zierlab.bsky.social
Genome Stability and Innate Immunity Lab at the Institute of Cancer Research, London
https://www.zierhutlab.org/
https://www.zierhutlab.org/
Great news to see this out now! Congratulations!
January 8, 2026 at 4:24 PM
Great news to see this out now! Congratulations!
I would also like to say that this was the first time I wrote a review across research groups, combining complementary expertise. It was a lot of fun, and I also learned a lot in the process.
January 6, 2026 at 10:44 AM
I would also like to say that this was the first time I wrote a review across research groups, combining complementary expertise. It was a lot of fun, and I also learned a lot in the process.
Excited to announce a new review article that Andreas Villunger @villungerlab.bsky.social, Dario Rizzotto (not on bsky) and I wrote. In this article, we discuss mitosis as a central cell cycle stage for integrating DNA damage, cell death and inflammatory responses. www.nature.com/articles/s41...
Mitotic errors as triggers of cell death and inflammation - Nature Cell Biology
Rizzotto et al. discuss the causes and consequences of deregulated mitosis that allow cells arrested in mitosis to escape to the next interphase, where they can initiate inflammatory signalling or und...
www.nature.com
January 6, 2026 at 10:43 AM
Excited to announce a new review article that Andreas Villunger @villungerlab.bsky.social, Dario Rizzotto (not on bsky) and I wrote. In this article, we discuss mitosis as a central cell cycle stage for integrating DNA damage, cell death and inflammatory responses. www.nature.com/articles/s41...
Reposted by Christian Zierhut
Parkes lab pre-print alert! ‘TMEM33 deletion potentiates anti-tumor CD8⁺ T cell immunity.’ Led by mtjackson101.bsky.social. Full bluetutorial follows! 1/10 www.biorxiv.org/content/10.6...
January 5, 2026 at 3:30 PM
Parkes lab pre-print alert! ‘TMEM33 deletion potentiates anti-tumor CD8⁺ T cell immunity.’ Led by mtjackson101.bsky.social. Full bluetutorial follows! 1/10 www.biorxiv.org/content/10.6...
Reposted by Christian Zierhut
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 16, 2025 at 4:29 PM
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Christian Zierhut
We are pleased to present our manuscript on the annotation of clear cell Renal Cell Carcinoma #GWAS risk loci, recently published in @commsbio.nature.com
www.nature.com/articles/s42...
#ccRCC #cancer #genetics #genomics #KidneyCancer
www.nature.com/articles/s42...
#ccRCC #cancer #genetics #genomics #KidneyCancer
Deciphering genetic susceptibility to clear cell renal cell carcinoma - Communications Biology
Integration of genome-wide association data with epigenomic and chromatin interaction data identifies target genes mediating clear cell renal cell carcinoma risk, implicating disrupted hypoxia signall...
www.nature.com
December 16, 2025 at 5:27 PM
We are pleased to present our manuscript on the annotation of clear cell Renal Cell Carcinoma #GWAS risk loci, recently published in @commsbio.nature.com
www.nature.com/articles/s42...
#ccRCC #cancer #genetics #genomics #KidneyCancer
www.nature.com/articles/s42...
#ccRCC #cancer #genetics #genomics #KidneyCancer
Fantastic! Congratulations!!
December 16, 2025 at 5:00 PM
Fantastic! Congratulations!!
And most of these appearances without even having won the mandate for a single constituency seat!
December 5, 2025 at 3:45 PM
And most of these appearances without even having won the mandate for a single constituency seat!
Awesome!! Congratulations!!
November 28, 2025 at 2:55 PM
Awesome!! Congratulations!!
Congratulations!!
November 27, 2025 at 6:52 AM
Congratulations!!
Fantastic news! Congratulations!
November 24, 2025 at 8:57 AM
Fantastic news! Congratulations!
Reposted by Christian Zierhut
The 21st Course on Epigenetics which will take place from March 25th to April 1st, 2026 at the Institut Curie (Paris).
The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at:
minilien.curie.fr/3avv47
The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at:
minilien.curie.fr/3avv47
Epigenetics - 21st Course on Epigenetics 2026: Towards a quantitative understanding of nuclear dynamics during development and diseases | Institut Curie Advanced Training
The aim of this course is to provide an overview of epigenetic mechanisms and their links to gene expression and chromatin dynamics, in different systems. The diverse functions of the nucleus involvin...
minilien.curie.fr
November 12, 2025 at 10:58 AM
The 21st Course on Epigenetics which will take place from March 25th to April 1st, 2026 at the Institut Curie (Paris).
The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at:
minilien.curie.fr/3avv47
The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at:
minilien.curie.fr/3avv47
Reposted by Christian Zierhut
Happy to share the “International Symposium on Chromosome Dynamics: from Structure to Cellular Function” that will be held in Japan 31st of May 2026 www.fbs.osaka-u.ac.jp/labs/fukagaw.... Registrations will open on December 1st! Plenty of opportunities to present your work! Hope to seeing you
International Symposium on Chromosome Dynamics from Structure to Cellular Function
www.fbs.osaka-u.ac.jp
November 21, 2025 at 6:33 PM
Happy to share the “International Symposium on Chromosome Dynamics: from Structure to Cellular Function” that will be held in Japan 31st of May 2026 www.fbs.osaka-u.ac.jp/labs/fukagaw.... Registrations will open on December 1st! Plenty of opportunities to present your work! Hope to seeing you
Looks like the link doesn't work.
November 20, 2025 at 10:51 AM
Looks like the link doesn't work.
Reposted by Christian Zierhut
My lab at the University of Birmingham have a fully funded 4 year PhD position available, focusing on the molecular mechanisms of the Alternative Lengthening of Telomeres (ALT).
Informal enquiries to r.a.broderick@bham.ac.uk
APPLICATION LINK:
sits.bham.ac.uk/urd/sits.urd...
Informal enquiries to r.a.broderick@bham.ac.uk
APPLICATION LINK:
sits.bham.ac.uk/urd/sits.urd...
IPP login screen
sits.bham.ac.uk
November 19, 2025 at 5:14 PM
My lab at the University of Birmingham have a fully funded 4 year PhD position available, focusing on the molecular mechanisms of the Alternative Lengthening of Telomeres (ALT).
Informal enquiries to r.a.broderick@bham.ac.uk
APPLICATION LINK:
sits.bham.ac.uk/urd/sits.urd...
Informal enquiries to r.a.broderick@bham.ac.uk
APPLICATION LINK:
sits.bham.ac.uk/urd/sits.urd...
Congratulations to Lauren Davies, the lab's first PhD student, who defended her thesis with flying colours yesterday! Special thanks to Lauren's examiners @eileenparkes.bsky.social and @mcclellandlab.bsky.social! Lauren will stay for a few months to finalise a manuscript - so watch this space!
November 19, 2025 at 2:18 PM
Congratulations to Lauren Davies, the lab's first PhD student, who defended her thesis with flying colours yesterday! Special thanks to Lauren's examiners @eileenparkes.bsky.social and @mcclellandlab.bsky.social! Lauren will stay for a few months to finalise a manuscript - so watch this space!
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 10:25 PM
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
Done! @jalview.bsky.social is such a hugely important resource, it would be awful to lose development support for this.
November 17, 2025 at 10:24 PM
Done! @jalview.bsky.social is such a hugely important resource, it would be awful to lose development support for this.
Fantastic! Great news! So well-deserved!
November 7, 2025 at 1:48 PM
Fantastic! Great news! So well-deserved!
Reposted by Christian Zierhut
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
tinyurl.com
November 6, 2025 at 11:05 PM
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
For everyone interested in art, my incredibly talented girlfriend Lara is auctioning one of her paintings to support @freedomfromtorture.bsky.social. The current bid is a bargain for her art, so snatch it up, and still get an incredibly good deal!
artauction.freedomfromtorture.org/auction/item...
artauction.freedomfromtorture.org/auction/item...
November 7, 2025 at 12:18 PM
For everyone interested in art, my incredibly talented girlfriend Lara is auctioning one of her paintings to support @freedomfromtorture.bsky.social. The current bid is a bargain for her art, so snatch it up, and still get an incredibly good deal!
artauction.freedomfromtorture.org/auction/item...
artauction.freedomfromtorture.org/auction/item...
Yes, that was exactly my thoughts as well. Frequently, human reviewers already focus too much on adding extra stuff that doesn't affect the main claims/conclusion, and with this focus on minutiae of individual claims and experiments, using AIs like qed for review purposes will worsen the situation.
November 7, 2025 at 10:50 AM
Yes, that was exactly my thoughts as well. Frequently, human reviewers already focus too much on adding extra stuff that doesn't affect the main claims/conclusion, and with this focus on minutiae of individual claims and experiments, using AIs like qed for review purposes will worsen the situation.
Reposted by Christian Zierhut
Interested in inherited chromosomal instability syndromes and DNA repair? We are looking for an enthusiastic person to join the Stewart lab at the University of Birmingham as a senior technician. Please checkout the job advert: www.jobs.ac.uk/job/DPH515/senior-research-technician
Senior Research Technician at University of Birmingham
An academic position as a Senior Research Technician is being advertised on jobs.ac.uk. Click now to find more details and explore additional academic job opportunities.
www.jobs.ac.uk
November 6, 2025 at 8:34 AM
Interested in inherited chromosomal instability syndromes and DNA repair? We are looking for an enthusiastic person to join the Stewart lab at the University of Birmingham as a senior technician. Please checkout the job advert: www.jobs.ac.uk/job/DPH515/senior-research-technician
Reposted by Christian Zierhut
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...
Senior Research Technician at University of Birmingham
Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
October 7, 2025 at 8:51 AM
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...