Bungo Akiyoshi
@bungoakiyoshi.bsky.social
Studying kinetochores in African trypanosome (kinetoplastid) and marine plankton (diplonemid) in Edinburgh
https://www.ed.ac.uk/biology/groups/akiyoshi
https://www.ed.ac.uk/biology/groups/akiyoshi
Pinned
My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...
Next generation open access??
www.jisc.ac.uk/news/all/lan...
www.jisc.ac.uk/news/all/lan...
Landmark publishing agreements for UK universities - Jisc
www.jisc.ac.uk
December 23, 2025 at 9:15 AM
Next generation open access??
www.jisc.ac.uk/news/all/lan...
www.jisc.ac.uk/news/all/lan...
Reposted by Bungo Akiyoshi
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
At the helm of JCS – Editors-in-Chief past, present… and future
The Editor-in-Chief (EIC) of Journal of Cell Science plays a key role in defining the overall vision of the journal, helping to decide on journal strategy, policy and priorities, and overseeing all co...
doi.org
December 22, 2025 at 10:33 AM
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
The discovery of the first kinetochore proteins (CENP-A, CENP-B, CENP-C) was reported by Bill Earnshaw and Naomi Rothfield in 1985 in Chromosoma. Forty years later, Chromosoma/Chromosome Research has published a special issue (most articles are open access)
link.springer.com/collections/...
link.springer.com/collections/...
40 years of CENP-A
In 1985, Earnshaw and Rothfield published in Chromosoma a landmark discovery of the centromere-specific protein CENP-A. Subsequent research has shown that ...
link.springer.com
December 22, 2025 at 10:09 AM
The discovery of the first kinetochore proteins (CENP-A, CENP-B, CENP-C) was reported by Bill Earnshaw and Naomi Rothfield in 1985 in Chromosoma. Forty years later, Chromosoma/Chromosome Research has published a special issue (most articles are open access)
link.springer.com/collections/...
link.springer.com/collections/...
Reposted by Bungo Akiyoshi
Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍
W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social
journals.biologists.com/jcs/article/...
W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social
journals.biologists.com/jcs/article/...
Evolutionary cell biology comes of age
Summary: This Perspective discusses how the discipline of evolutionary cell biology, by integrating evolutionary theory, comparative physiology and modern molecular approaches, works to understand how...
journals.biologists.com
December 19, 2025 at 4:13 PM
Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍
W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social
journals.biologists.com/jcs/article/...
W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social
journals.biologists.com/jcs/article/...
Reposted by Bungo Akiyoshi
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reverse gyrase and 3D genome architecture suppress hyperthermophile genome instability arising from horizontal gene transfer
Reverse gyrase (Rgy), a distinctive topoisomerase conserved in all hyperthermophiles, has the unique ability to introduce positive DNA supercoils. It has long been hypothesized that Rgy overwinds geno...
www.biorxiv.org
December 11, 2025 at 6:40 AM
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Mitosis is beautiful
December 8, 2025 at 2:30 PM
Mitosis is beautiful
Yes, this experiment says a lot...
Self-citations are not elegant, yet I feel that much of what we need to know about the robustness of "LLPS scaffolds" is summarized in this figure
doi.org/10.1016/j.mo...
doi.org/10.1016/j.mo...
December 5, 2025 at 1:20 PM
Yes, this experiment says a lot...
Reposted by Bungo Akiyoshi
Self-citations are not elegant, yet I feel that much of what we need to know about the robustness of "LLPS scaffolds" is summarized in this figure
doi.org/10.1016/j.mo...
doi.org/10.1016/j.mo...
December 5, 2025 at 10:43 AM
Self-citations are not elegant, yet I feel that much of what we need to know about the robustness of "LLPS scaffolds" is summarized in this figure
doi.org/10.1016/j.mo...
doi.org/10.1016/j.mo...
Reposted by Bungo Akiyoshi
#Diplonemids are among the most diverse & abundant #protists in the deep #ocean. This study localises >5,000 proteins of #Paradiplonema papillatum, revealing #organelle compartmentalisation, including a membrane coated with carbohydrate-degrading enzymes @plosbiology.org 🧪 plos.io/3XvmpIO
December 4, 2025 at 5:30 PM
#Diplonemids are among the most diverse & abundant #protists in the deep #ocean. This study localises >5,000 proteins of #Paradiplonema papillatum, revealing #organelle compartmentalisation, including a membrane coated with carbohydrate-degrading enzymes @plosbiology.org 🧪 plos.io/3XvmpIO
Reposted by Bungo Akiyoshi
whether you agree with Andrea or not, what he is doing is very important for a healthy scientific culture. Thank you @andrea-musacchio.bsky.social for setting a great example for all of us: Speak your mind even if it is against the mainstream flow.
December 2, 2025 at 7:00 AM
whether you agree with Andrea or not, what he is doing is very important for a healthy scientific culture. Thank you @andrea-musacchio.bsky.social for setting a great example for all of us: Speak your mind even if it is against the mainstream flow.
There is always pseudoscience out there some of which are excellent at gaining momentum (and people, money, power) because they sound attractive. But pseudoscience is pseudoscience. Time will tell. As a scientist, one should judge what's right/wrong by themselves
November 29, 2025 at 6:12 PM
There is always pseudoscience out there some of which are excellent at gaining momentum (and people, money, power) because they sound attractive. But pseudoscience is pseudoscience. Time will tell. As a scientist, one should judge what's right/wrong by themselves
Any field/university/company/president that cannot respond to external critiques is destined to collapse and vanish at some point. It may take long time unfortunately but time will tell who is right and who is wrong
November 29, 2025 at 5:53 PM
Any field/university/company/president that cannot respond to external critiques is destined to collapse and vanish at some point. It may take long time unfortunately but time will tell who is right and who is wrong
Reposted by Bungo Akiyoshi
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
#protistsonsky 🧵
November 25, 2025 at 8:41 PM
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
#protistsonsky 🧵
Reposted by Bungo Akiyoshi
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 25, 2025 at 12:16 PM
A new and fascinating story from @bencarty.bsky.social and the group, with crucial help from the teams of @naltemose.bsky.social, Simona Giunta, and @dfachinetti.bsky.social. Many thanks to all for a fantastic collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Bungo Akiyoshi
I however wonder why a new supergroup was erected (Disparia) when the existing supergroup Promethea precisely describes this grouping? Promethea was published here: www.cell.com/iscience/ful...
Phylogenetic position and mitochondrial genome evolution of “orphan” eukaryotic lineages
Evolutionary biology; Phylogenetics
www.cell.com
November 21, 2025 at 9:30 AM
I however wonder why a new supergroup was erected (Disparia) when the existing supergroup Promethea precisely describes this grouping? Promethea was published here: www.cell.com/iscience/ful...
Reposted by Bungo Akiyoshi
Why IDPs Are Poor Candidates for Homotypic LLPS
🧵👇A thread
🧵👇A thread
November 20, 2025 at 6:32 PM
Why IDPs Are Poor Candidates for Homotypic LLPS
🧵👇A thread
🧵👇A thread
Reposted by Bungo Akiyoshi
Why LLPS Scaffolds Cannot Exist – A Thermodynamic Thread
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
November 19, 2025 at 5:48 AM
Why LLPS Scaffolds Cannot Exist – A Thermodynamic Thread
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
If you consider arguments logical, please share. Else please expose logical faults
🧵👇
Trypanosoma
First we traced the evolutionary history of AMT1 (aka MTA1), the main 6mA enzyme in eukaryotes. We find that a complex repertoire including AMT1 and its heterodimeric partner AMT6/7 can be traced back to the Last Eukaryotic Common Ancestor. Same goes for the RNA methyltransferases METTL3/14. 2/9
November 18, 2025 at 1:22 PM
Trypanosoma
Reposted by Bungo Akiyoshi
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 10:25 PM
Deadline 18th Nov! Please write to express your support for continued funding for Jalview!
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...
Write a letter of support to help keep Jalview funded!
Jalview’s core funding from the Wellcome Trust ends in 2026, and we are now preparing an application to the UK’s BBSRC to support Jalview into the next decade. You can help us keep Jalview available ...
discourse.jalview.org
November 17, 2025 at 9:55 PM
I just found this now. @jalview.bsky.social team needs your support for their BBSRC application. Deadline tomorrow!
discourse.jalview.org/t/write-a-le...
discourse.jalview.org/t/write-a-le...