Aga Gambus
@agagambus.bsky.social
Researcher, group leader, professor, mum of 2. Interested in DNA replication and damage, ubiquitylation, cell cycle, molecular and structural biochemistry.
Last 3 days to apply for this post. Deadline 27/10/25
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...
Senior Research Technician at University of Birmingham
Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
October 24, 2025 at 8:21 AM
Last 3 days to apply for this post. Deadline 27/10/25
Reposted by Aga Gambus
Now out in print: Targeting DNA damage in ageing: towards supercharging DNA repair. New perspectives how we could tackle cancer and aging at their mechanistic root cause: I
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Targeting DNA damage in ageing: towards supercharging DNA repair - Nature Reviews Drug Discovery
DNA damage to the somatic genome has been identified as a major cause of ageing. This Perspective provides an overview of current understanding of the role of genome instability in the ageing process and assesses therapeutic strategies targeting the cellular response to DNA damage to delay ageing and prevent associated diseases.
www.nature.com
September 30, 2025 at 3:24 PM
Now out in print: Targeting DNA damage in ageing: towards supercharging DNA repair. New perspectives how we could tackle cancer and aging at their mechanistic root cause: I
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Aga Gambus
A three-year PhD position is available within the team, starting no later than October 2026, to decipher the molecular signatures of chromosomal instability in response to replication stress and how nuclear architecture shapes these signatures in yeast. Please RT.
fr.scribd.com/document/934...
fr.scribd.com/document/934...
Offer PhD Position Team Lambert | PDF | Genetics | Life Sciences
3-year PhD offer in biology to mechanisms of complex rearrangements of the genome.
fr.scribd.com
October 19, 2025 at 7:32 PM
A three-year PhD position is available within the team, starting no later than October 2026, to decipher the molecular signatures of chromosomal instability in response to replication stress and how nuclear architecture shapes these signatures in yeast. Please RT.
fr.scribd.com/document/934...
fr.scribd.com/document/934...
Reposted by Aga Gambus
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...
www.nature.com
October 16, 2025 at 2:06 PM
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
To explain - the appointed candidate (including EU/international candidates) can do a PhD as a "staff member" upon paying a small fee. People not interested in doing PhD are of course also invited to apply :). Please share.
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...
Senior Research Technician at University of Birmingham
Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
October 15, 2025 at 8:43 AM
To explain - the appointed candidate (including EU/international candidates) can do a PhD as a "staff member" upon paying a small fee. People not interested in doing PhD are of course also invited to apply :). Please share.
Fully-funded 4-years competitive PhD project in our lab (MIBTP-doctoral-training-programme. p97 unfoldase functions during DNA replication. Open to UK/international candidates. Please get in touch for informal enquiries. Deadline 27th of November. Please share.
warwick.ac.uk/fac/cross_fa...
warwick.ac.uk/fac/cross_fa...
Professor Aga Gambus
Professor Aga Gambus
warwick.ac.uk
October 15, 2025 at 8:41 AM
Fully-funded 4-years competitive PhD project in our lab (MIBTP-doctoral-training-programme. p97 unfoldase functions during DNA replication. Open to UK/international candidates. Please get in touch for informal enquiries. Deadline 27th of November. Please share.
warwick.ac.uk/fac/cross_fa...
warwick.ac.uk/fac/cross_fa...
Reposted by Aga Gambus
New BBSRC funded PhD opportunity in my group with Inspiralis Ltd and @conradn.bsky.social. If you are interested in RNA - protein interactions and RNA modifications check the details below for how to apply. @nrpdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social tinyurl.com/bdzvn4dr
How do RNA molecules shape genome regulation in the nervous system? (AKAY_U26CASE) | Doctoral Training Partnership
This PhD project will investigate how RNA modifications influence the activity of topoisomerase I (TOP1), a crucial enzyme that regulates DNA supercoiling during replication and transcription. Using C...
biodtp.norwichresearchpark.ac.uk
October 12, 2025 at 7:43 PM
New BBSRC funded PhD opportunity in my group with Inspiralis Ltd and @conradn.bsky.social. If you are interested in RNA - protein interactions and RNA modifications check the details below for how to apply. @nrpdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social tinyurl.com/bdzvn4dr
Reposted by Aga Gambus
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
John Innes Centre
jobs.jic.ac.uk
October 8, 2025 at 9:04 AM
Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!
jobs.jic.ac.uk/Details.asp?...
Please repost!
jobs.jic.ac.uk/Details.asp?...
Reposted by Aga Gambus
A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...
Application – EMBL International PhD Programme
www.embl.org
October 9, 2025 at 4:51 AM
A reminder that the PhD program for EMBL is open for winter recruitment round. If you want to understand life at a molecular level and have a quantitative science (you don't have to have done biology - we love our mathematicians/physcists/chemists!) apply www.embl.org/about/info/e...
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...
Senior Research Technician at University of Birmingham
Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.
www.jobs.ac.uk
October 7, 2025 at 8:51 AM
We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...
www.jobs.ac.uk/job/DOW912/s...
Reposted by Aga Gambus
The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
September 20, 2025 at 7:43 AM
The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Reposted by Aga Gambus
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
September 18, 2025 at 8:02 PM
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Reposted by Aga Gambus
Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.
September 11, 2025 at 4:34 PM
Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.
Reposted by Aga Gambus
Assistant Prof post in bacterial genomics @unibirmingham.bsky.social Come and join us!!
@imibirmingham.bsky.social
www.jobs.ac.uk/job/DOO184/a...
@imibirmingham.bsky.social
www.jobs.ac.uk/job/DOO184/a...
Assistant Professor (Research and Education) in Bacterial Genomics at University of Birmingham
Looking for a new job opportunity in academia? Check out this job opening for a Assistant Professor (Research and Education) in Bacterial Genomics on jobs.ac.uk!
www.jobs.ac.uk
September 4, 2025 at 8:22 AM
Assistant Prof post in bacterial genomics @unibirmingham.bsky.social Come and join us!!
@imibirmingham.bsky.social
www.jobs.ac.uk/job/DOO184/a...
@imibirmingham.bsky.social
www.jobs.ac.uk/job/DOO184/a...
Reposted by Aga Gambus
A good way to think about institutional research culture!
September 1, 2025 at 7:57 AM
A good way to think about institutional research culture!
Reposted by Aga Gambus
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
August 28, 2025 at 6:34 AM
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
www.nature.com/naturecareer...
Please repost!
Congratulations to Georgia on her graduation!!
July 14, 2025 at 11:39 AM
Congratulations to Georgia on her graduation!!
Very exciting new technology manuscript from @alicepyne.bsky.social lab!
High-res AFM + AI pipeline quantifies complex DNA topology. t.co/qxD7o7ASl6
Very happy to contribute with @singlemoleculenev.bsky.social plasmids replicating past barriers in Xenopus egg extract.
Congratulation everyone!
High-res AFM + AI pipeline quantifies complex DNA topology. t.co/qxD7o7ASl6
Very happy to contribute with @singlemoleculenev.bsky.social plasmids replicating past barriers in Xenopus egg extract.
Congratulation everyone!
https://doi.org/10.1038/s41467-025-60559-x
t.co
July 11, 2025 at 12:18 PM
Very exciting new technology manuscript from @alicepyne.bsky.social lab!
High-res AFM + AI pipeline quantifies complex DNA topology. t.co/qxD7o7ASl6
Very happy to contribute with @singlemoleculenev.bsky.social plasmids replicating past barriers in Xenopus egg extract.
Congratulation everyone!
High-res AFM + AI pipeline quantifies complex DNA topology. t.co/qxD7o7ASl6
Very happy to contribute with @singlemoleculenev.bsky.social plasmids replicating past barriers in Xenopus egg extract.
Congratulation everyone!
Last days of early bird registration for BCGB conference with exciting international speakers - see below. The conference is 11-12 of September in Birmingham UK. Abstract submission extended until 20th of July! Many spots for talks uplifted from abstracts.
uobevents.eventsair.com/birmingham-c...
uobevents.eventsair.com/birmingham-c...
July 11, 2025 at 12:14 PM
Last days of early bird registration for BCGB conference with exciting international speakers - see below. The conference is 11-12 of September in Birmingham UK. Abstract submission extended until 20th of July! Many spots for talks uplifted from abstracts.
uobevents.eventsair.com/birmingham-c...
uobevents.eventsair.com/birmingham-c...
Reposted by Aga Gambus
Apply to our PhD program!!
🧬 Looking for a PhD position in molecular or developmental biology? 🔬
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
July 10, 2025 at 6:56 PM
Apply to our PhD program!!
Reposted by Aga Gambus
📣 ERC Synergy Grant 2026 call for proposals is now open!
Application deadline 5 November 2025.
📝 Groups of 2-4 researchers
📝 Jointly addressing ambitious problems & with different skills
Application portal 👉 europa.eu/!XpwptY
General info 👉 europa.eu/!PR6gt8
#ERCSyG #FrontierResearch
Application deadline 5 November 2025.
📝 Groups of 2-4 researchers
📝 Jointly addressing ambitious problems & with different skills
Application portal 👉 europa.eu/!XpwptY
General info 👉 europa.eu/!PR6gt8
#ERCSyG #FrontierResearch
July 10, 2025 at 2:47 PM
📣 ERC Synergy Grant 2026 call for proposals is now open!
Application deadline 5 November 2025.
📝 Groups of 2-4 researchers
📝 Jointly addressing ambitious problems & with different skills
Application portal 👉 europa.eu/!XpwptY
General info 👉 europa.eu/!PR6gt8
#ERCSyG #FrontierResearch
Application deadline 5 November 2025.
📝 Groups of 2-4 researchers
📝 Jointly addressing ambitious problems & with different skills
Application portal 👉 europa.eu/!XpwptY
General info 👉 europa.eu/!PR6gt8
#ERCSyG #FrontierResearch
It is finally out 👍😀. Great job of the team (mostly absent from Bsky) and @m-saponaro.bsky.social
CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS url: academic.oup.com/nar/article/...
CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS url: academic.oup.com/nar/article/...
CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS
Abstract. Disassembly of the replication machinery (replisome) from chromatin is an active process driven by two ubiquitin ligases Cul2LRR1 and TRAIP, whic
academic.oup.com
July 10, 2025 at 2:55 PM
It is finally out 👍😀. Great job of the team (mostly absent from Bsky) and @m-saponaro.bsky.social
CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS url: academic.oup.com/nar/article/...
CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS url: academic.oup.com/nar/article/...
Reposted by Aga Gambus
All about the 2026 ERC grant application and evaluation process! ✍️
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
July 3, 2025 at 11:27 AM
All about the 2026 ERC grant application and evaluation process! ✍️
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Are you new to ERC grants?
Then join us for a live webinar on 10 July at 15:00 CEST, tailored for researchers who are just starting out in their attempt to get an ERC grant.
Watch 👉 europa.eu/!3rGdWB
Reposted by Aga Gambus
Genome Biology conference in Birmingham UK in September. Check out our great invited speakers! Lots of slots for talks selected from abstracts too! Please repost 😀
The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
June 25, 2025 at 3:41 PM
Genome Biology conference in Birmingham UK in September. Check out our great invited speakers! Lots of slots for talks selected from abstracts too! Please repost 😀
Congratulations Paloma! Great work 😀👍
Delighted to announce that our paper showing the generation of iPSc from a MDS patient & how CEBPA drives disease progression is finally out in Nature Comms!
A big thanks to everybody involved & the great collaborators that have made it possible!
10.1038/s41467-025-60192-8
A big thanks to everybody involved & the great collaborators that have made it possible!
10.1038/s41467-025-60192-8
July 1, 2025 at 8:06 PM
Congratulations Paloma! Great work 😀👍