Ferenc Mueller
@ferencmueller.bsky.social
Reposted by Ferenc Mueller
🐟Meet the DANIO-ReCODE team!🐟
This week:Parth Bhatia and Prof @ferencmueller.bsky.social from @unibirmingham.bsky.social
Parth´s research focuses on the annotation,characterisation and dynamics of cis-regulatory elements (CREs) in telencephalon injury
📢Stay tuned! #DANIO #MSCA @obog.bsky.social
This week:Parth Bhatia and Prof @ferencmueller.bsky.social from @unibirmingham.bsky.social
Parth´s research focuses on the annotation,characterisation and dynamics of cis-regulatory elements (CREs) in telencephalon injury
📢Stay tuned! #DANIO #MSCA @obog.bsky.social
November 11, 2025 at 8:30 AM
🐟Meet the DANIO-ReCODE team!🐟
This week:Parth Bhatia and Prof @ferencmueller.bsky.social from @unibirmingham.bsky.social
Parth´s research focuses on the annotation,characterisation and dynamics of cis-regulatory elements (CREs) in telencephalon injury
📢Stay tuned! #DANIO #MSCA @obog.bsky.social
This week:Parth Bhatia and Prof @ferencmueller.bsky.social from @unibirmingham.bsky.social
Parth´s research focuses on the annotation,characterisation and dynamics of cis-regulatory elements (CREs) in telencephalon injury
📢Stay tuned! #DANIO #MSCA @obog.bsky.social
PhD position (funded, competitive, shorturl.at/3zcmP, application details: shorturl.at/RDzd6) and postdoctoral fellow position (shorturl.at/UWtUV) are available in our lab. Topics: transcription regulation control of metabolism in development and upon toxic chemical exposures.
How does the interplay between metabolism control and gene regulation shape embryo development? at University of Birmingham on FindAPhD.com
PhD Project - How does the interplay between metabolism control and gene regulation shape embryo development? at University of Birmingham, listed on FindAPhD.com
shorturl.at
October 28, 2025 at 11:28 AM
PhD position (funded, competitive, shorturl.at/3zcmP, application details: shorturl.at/RDzd6) and postdoctoral fellow position (shorturl.at/UWtUV) are available in our lab. Topics: transcription regulation control of metabolism in development and upon toxic chemical exposures.
Reposted by Ferenc Mueller
What is a promoter? And how does it work?
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
Enhancer-promoter compatibility is mediated by the promoter-proximal region
Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...
www.biorxiv.org
October 16, 2025 at 3:06 PM
What is a promoter? And how does it work?
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
Reposted by Ferenc Mueller
If you've benefited from ZebrafishRock and its community, you can thank ZFIN. i.e. ZebrafishRock is actually Kevin searching ZFIN
Want an easy way to support your model organism databases? Cite them!
Depending on the #zebrafish data you retrieve from ZFIN, you can show your support by using one of the formats below 🙏 🧪 #ZebrafishFunFacts
Depending on the #zebrafish data you retrieve from ZFIN, you can show your support by using one of the formats below 🙏 🧪 #ZebrafishFunFacts
![Citing ZFIN. We recommend the following formats for citing ZFIN in publications. For a general reference to the database, cite Bradford et al. 2022. For citing a specific entry in ZFIN: [Type of] data for this paper were retrieved from ZFIN, University of Oregon, Eugene, OR 97404-5274; URL: http://zfin.org/; [the date you retrieved the data cited].](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:lmndrquzjoynsxgz7rcn5unj/bafkreicstoaakfnbcpp5pgpqjpzwdcaclgr6diy7clnhmmsw32v4mnrare@jpeg)
October 22, 2025 at 5:12 PM
If you've benefited from ZebrafishRock and its community, you can thank ZFIN. i.e. ZebrafishRock is actually Kevin searching ZFIN
Reposted by Ferenc Mueller
🏆 First Prize – DevBio Art Contest 🖼️
“A Model Meeting” by Karla Akari Garcia
Inspired by The Quaker Meeting, this watercolor honors animal research models, from mouse to axolotl, that have advanced developmental biology 🎨 A tribute to science’s often unsung heroes. #DevBioArt
Inspired by The Quaker Meeting, this watercolor honors animal research models, from mouse to axolotl, that have advanced developmental biology 🎨 A tribute to science’s often unsung heroes. #DevBioArt
October 22, 2025 at 8:19 PM
🏆 First Prize – DevBio Art Contest 🖼️
“A Model Meeting” by Karla Akari Garcia
Inspired by The Quaker Meeting, this watercolor honors animal research models, from mouse to axolotl, that have advanced developmental biology 🎨 A tribute to science’s often unsung heroes. #DevBioArt
Inspired by The Quaker Meeting, this watercolor honors animal research models, from mouse to axolotl, that have advanced developmental biology 🎨 A tribute to science’s often unsung heroes. #DevBioArt
Reposted by Ferenc Mueller
🐟DANIO-ReCODE MSCA DN🐟
As part of Consortium DCs training, PhDs attended a "Career Development Workshop" led by Amani Said, career coach.
They took part in two sessions focused on how maximizing their PhD journey
#DANIO #MSCA @obog.bsky.social @ec.europa.eu @cabd-upo-csic.bsky.social
As part of Consortium DCs training, PhDs attended a "Career Development Workshop" led by Amani Said, career coach.
They took part in two sessions focused on how maximizing their PhD journey
#DANIO #MSCA @obog.bsky.social @ec.europa.eu @cabd-upo-csic.bsky.social
October 10, 2025 at 8:23 AM
🐟DANIO-ReCODE MSCA DN🐟
As part of Consortium DCs training, PhDs attended a "Career Development Workshop" led by Amani Said, career coach.
They took part in two sessions focused on how maximizing their PhD journey
#DANIO #MSCA @obog.bsky.social @ec.europa.eu @cabd-upo-csic.bsky.social
As part of Consortium DCs training, PhDs attended a "Career Development Workshop" led by Amani Said, career coach.
They took part in two sessions focused on how maximizing their PhD journey
#DANIO #MSCA @obog.bsky.social @ec.europa.eu @cabd-upo-csic.bsky.social
Reposted by Ferenc Mueller
It is with great sadness that we heard of John Gurdon’s passing this week. Not just one of our 100 extraordinary biologists, but truly one of a kind, he was a pioneer, whose vision and personality inspired biologists worldwide.
October 10, 2025 at 2:11 PM
It is with great sadness that we heard of John Gurdon’s passing this week. Not just one of our 100 extraordinary biologists, but truly one of a kind, he was a pioneer, whose vision and personality inspired biologists worldwide.
Reposted by Ferenc Mueller
Cell nuclei movements (color-coded for direction) during early zebrafish development. Credit to Dr. Philipp Keller @hhmijanelia.bsky.social. #ZebrafishZunday
October 5, 2025 at 3:32 PM
Cell nuclei movements (color-coded for direction) during early zebrafish development. Credit to Dr. Philipp Keller @hhmijanelia.bsky.social. #ZebrafishZunday
Reposted by Ferenc Mueller
Terrific new feature presented by @theo.io on @pathoplexus.org called SeqSets for generating DOIs for sequence subsets used in publications, that can then be tracked for impact via CrossRef that will allow data generators to track impact! #IMMEMXiV
September 19, 2025 at 11:10 AM
Terrific new feature presented by @theo.io on @pathoplexus.org called SeqSets for generating DOIs for sequence subsets used in publications, that can then be tracked for impact via CrossRef that will allow data generators to track impact! #IMMEMXiV
Reposted by Ferenc Mueller
Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.
September 11, 2025 at 4:34 PM
Honoured to be in Birmingham to mark Bryan Turner’s retirement- a gentleman and giant of epigenetics.
Reposted by Ferenc Mueller
Interested in zebrafish as a disease model for NF1? We are seeking a motivated PhD student to join our team and become an expert in high-resolution imaging/precise genome editing in collab with AZ. gw4biomed.ac.uk/establishing... @lsiexeter.bsky.social @zebrafishrock.bsky.social @izfs.bsky.social
gw4biomed.ac.uk
September 2, 2025 at 2:04 PM
Interested in zebrafish as a disease model for NF1? We are seeking a motivated PhD student to join our team and become an expert in high-resolution imaging/precise genome editing in collab with AZ. gw4biomed.ac.uk/establishing... @lsiexeter.bsky.social @zebrafishrock.bsky.social @izfs.bsky.social
Reposted by Ferenc Mueller
This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇
August 18, 2025 at 1:00 PM
This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇
Reposted by Ferenc Mueller
#zebrafish genome update, our T2T assembly of the inbred strain of AB (M-AB) generated by my buddy Nori Sakai has now been released at NCBI and will be a second reference genome for zebrafish (GRCz12ab):
JBQAYU000000000.1 Danio rerio :: NCBI
www.ncbi.nlm.nih.gov
August 15, 2025 at 4:17 PM
#zebrafish genome update, our T2T assembly of the inbred strain of AB (M-AB) generated by my buddy Nori Sakai has now been released at NCBI and will be a second reference genome for zebrafish (GRCz12ab):
Reposted by Ferenc Mueller
Check out our new collaborative preprint about Affinity-ligand purification of native human low-abundance multi-protein complexes doi.org/10.1101/2025...
Affinity-ligand purification of native human low-abundance multi-protein complexes for structure determination
In human cells, large multi-protein transcription co-activators, such as chromatin remodelers or histone acetyltransferases, play critical roles in gene-expression regulation and are often implicated ...
doi.org
August 12, 2025 at 7:30 AM
Check out our new collaborative preprint about Affinity-ligand purification of native human low-abundance multi-protein complexes doi.org/10.1101/2025...
Reposted by Ferenc Mueller
Excited to share the latest work from the lab led by @eharo84.bsky.social, in which we have used synthetic biology to explore the mechanisms by which different types of long-range enhancers ensure robust and precise developmental gene expression
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Synthetic engineering demonstrates that synergy among enhancers involves an increase in transcriptionally productive enhancer-gene contacts
Enhancers are non-coding cis-regulatory elements that control the expression of distally located genes in a tissue- and time-specific manner. Recent studies indicate that enhancers can differ in their...
www.biorxiv.org
August 11, 2025 at 2:56 PM
Excited to share the latest work from the lab led by @eharo84.bsky.social, in which we have used synthetic biology to explore the mechanisms by which different types of long-range enhancers ensure robust and precise developmental gene expression
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ferenc Mueller
📢One month left to apply to our Group Leader position!
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
August 8, 2025 at 6:17 AM
📢One month left to apply to our Group Leader position!
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
Reposted by Ferenc Mueller
So excited and grateful to receive R24 NOA from NIH ORIP to create an integrated #zebrafish omics, histology and microCT 3D atlas!
Looking forward to an exciting work with Dr. Postlethwait of U of Oregon, who is the co-PI of the grant.
Looking forward to an exciting work with Dr. Postlethwait of U of Oregon, who is the co-PI of the grant.
August 5, 2025 at 2:38 PM
So excited and grateful to receive R24 NOA from NIH ORIP to create an integrated #zebrafish omics, histology and microCT 3D atlas!
Looking forward to an exciting work with Dr. Postlethwait of U of Oregon, who is the co-PI of the grant.
Looking forward to an exciting work with Dr. Postlethwait of U of Oregon, who is the co-PI of the grant.
Reposted by Ferenc Mueller
Wrote a big review with my friend and colleague @varshneylab.social on the state-of-the-art in CRISPR used experimentally in vivo. We wanted to focus on their use in experimental vertebrate animals (apparently passé now but we persist).
CRISPR-based functional genomics tools in vertebrate models - Experimental & Molecular Medicine
Recent advances in DNA sequencing have allowed scientists to gather vast amounts of genetic data, but understanding what those sequences actually do requires additional tools that allow scientists to ...
www.nature.com
July 31, 2025 at 4:08 PM
Wrote a big review with my friend and colleague @varshneylab.social on the state-of-the-art in CRISPR used experimentally in vivo. We wanted to focus on their use in experimental vertebrate animals (apparently passé now but we persist).
#IZFC2025 #zebrafish #DANIO-CODE data coordination centre is back online. Note changed address: danio-code-dcc.genereg.net
DANIO-CODE DCC
This Data Coordination Center allows DANIO-CODE consortium members to submit and view their data sets annotated with standard metadata nomenclatures.
danio-code-dcc.genereg.net
July 13, 2025 at 12:23 PM
#IZFC2025 #zebrafish #DANIO-CODE data coordination centre is back online. Note changed address: danio-code-dcc.genereg.net
Reposted by Ferenc Mueller
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
July 11, 2025 at 10:40 PM
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
July 11, 2025 at 9:28 PM
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
Reposted by Ferenc Mueller
Genome Biology conference in Birmingham UK in September. Check out our great invited speakers! Lots of slots for talks selected from abstracts too! Please repost 😀
The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
June 25, 2025 at 3:41 PM
Genome Biology conference in Birmingham UK in September. Check out our great invited speakers! Lots of slots for talks selected from abstracts too! Please repost 😀
Reposted by Ferenc Mueller
Do you use EMBL-EBI data resources? We would really appreciate your feedback!
Our Interim Director Jo McEntyre explains how you can help us demonstrate the value of our data resources: www.ebi.ac.uk/about/news/a...
Survey closes on 16 July: www.surveymonkey.com/r/QGFMBH8?ch...
Thank you!
Our Interim Director Jo McEntyre explains how you can help us demonstrate the value of our data resources: www.ebi.ac.uk/about/news/a...
Survey closes on 16 July: www.surveymonkey.com/r/QGFMBH8?ch...
Thank you!
User survey to understand the value of open data resources
EMBL-EBI user survey opens – please complete it before 16 July
www.ebi.ac.uk
June 30, 2025 at 10:42 AM
Do you use EMBL-EBI data resources? We would really appreciate your feedback!
Our Interim Director Jo McEntyre explains how you can help us demonstrate the value of our data resources: www.ebi.ac.uk/about/news/a...
Survey closes on 16 July: www.surveymonkey.com/r/QGFMBH8?ch...
Thank you!
Our Interim Director Jo McEntyre explains how you can help us demonstrate the value of our data resources: www.ebi.ac.uk/about/news/a...
Survey closes on 16 July: www.surveymonkey.com/r/QGFMBH8?ch...
Thank you!
Reposted by Ferenc Mueller
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
https://go.nature.com/40wPxkB
’We couldn’t live without it’: the UCSC Genome Browser turns 25
After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.
go.nature.com
June 30, 2025 at 11:49 AM
After a quarter of a century, the UCSC Genome Browser remains an essential tool for navigating the genome and understanding its structure, function and clinical impact
https://go.nature.com/40wPxkB
https://go.nature.com/40wPxkB
The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
June 25, 2025 at 9:16 AM
The Birmingham Centre for Genome Biology invites you
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!
to join us at our 10th year anniversary conference!
Website and Registration here: shorturl.at/rvJSr
Fantastic speakers, and a very cost-efficient meeting for ECRs and all. Talk slots are available. See you in Brum on 11-12th September 2025!