Lori Passmore
@lapassmore.bsky.social
Molecular biologist. Group leader at MRC LMB Cambridge UK. Fellow at Clare Hall college. #CryoEM #RNAbiology #DNArepair
Views/opinions are my own.
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/lori-passmore/
Views/opinions are my own.
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/lori-passmore/
Reposted by Lori Passmore
Join us on Monday 13th October at 11am for an #LMBSeminar from Bonnie Bassler on ‘Quorum sensing across domains: From viruses to bacteria to eukaryotes’
Visit our website for more info: www2.mrc-lmb.cam.ac.uk/news-and-eve...
Visit our website for more info: www2.mrc-lmb.cam.ac.uk/news-and-eve...
October 9, 2025 at 8:44 AM
Join us on Monday 13th October at 11am for an #LMBSeminar from Bonnie Bassler on ‘Quorum sensing across domains: From viruses to bacteria to eukaryotes’
Visit our website for more info: www2.mrc-lmb.cam.ac.uk/news-and-eve...
Visit our website for more info: www2.mrc-lmb.cam.ac.uk/news-and-eve...
Reposted by Lori Passmore
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
October 8, 2025 at 9:45 PM
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
Reposted by Lori Passmore
Start independent research at the JIC with us 👇.
Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.
Please do get in touch by email if you'd like to know more 👍
Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.
Please do get in touch by email if you'd like to know more 👍
VACANCY - Independent research fellowships leading to tenured positions
We’re inviting applications from outstanding researchers who either hold, or wish to apply for, Independent Research Fellowships.
APPLICATION DEADLINE: 10 November 2025
Click here to apply: jic.link/Fellows
We’re inviting applications from outstanding researchers who either hold, or wish to apply for, Independent Research Fellowships.
APPLICATION DEADLINE: 10 November 2025
Click here to apply: jic.link/Fellows
October 3, 2025 at 6:36 PM
Start independent research at the JIC with us 👇.
Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.
Please do get in touch by email if you'd like to know more 👍
Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes.
Please do get in touch by email if you'd like to know more 👍
Just a reminder that August is peak school holidays in the UK, but also more broadly in Europe and in Canada. If you schedule conferences during August you exclude a large proportion of people from these regions who have family obligations.
September 22, 2025 at 8:33 AM
Just a reminder that August is peak school holidays in the UK, but also more broadly in Europe and in Canada. If you schedule conferences during August you exclude a large proportion of people from these regions who have family obligations.
Reposted by Lori Passmore
The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
September 20, 2025 at 7:43 AM
The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.
Start mining data now: dataminer.depmap.sanger.ac.uk
Reposted by Lori Passmore
We are hiring-join us!
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
September 8, 2025 at 10:31 AM
We are hiring-join us!
Reposted by Lori Passmore
Just one more week left to get an application in! Starting my lab at the Perutz and the @viennabiocenter.bsky.social has been a fantastic opportunity that shaped me as a scientist!
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details ➡️ tinyurl.com/3fbkp89c
September 10, 2025 at 5:32 PM
Just one more week left to get an application in! Starting my lab at the Perutz and the @viennabiocenter.bsky.social has been a fantastic opportunity that shaped me as a scientist!
Reposted by Lori Passmore
Great start to the EMBL translation control meeting with a keynote from @lapassmore.bsky.social. Excited for all the science to come. #EMBLProtein
September 3, 2025 at 6:15 PM
Great start to the EMBL translation control meeting with a keynote from @lapassmore.bsky.social. Excited for all the science to come. #EMBLProtein
Reposted by Lori Passmore
Are you a postdoc interested in the mechanisms of disease?
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
www.path.ox.ac.uk
September 1, 2025 at 2:39 PM
Are you a postdoc interested in the mechanisms of disease?
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Unprompted, the 14yo told me she has a deep hatred for Comic Sans.
I love that kid so much.
I love that kid so much.
August 27, 2025 at 4:34 PM
Unprompted, the 14yo told me she has a deep hatred for Comic Sans.
I love that kid so much.
I love that kid so much.
Reposted by Lori Passmore
Fantastic talk by Ethan showcasing our work with @lapassmore.bsky.social lab at @cshlmeetings.bsky.social #RNAPR25! Hurray Ethan!
August 20, 2025 at 5:51 PM
Fantastic talk by Ethan showcasing our work with @lapassmore.bsky.social lab at @cshlmeetings.bsky.social #RNAPR25! Hurray Ethan!
Reposted by Lori Passmore
⏰Early Bird and Talk Submission Deadline closing soon - Tuesday 26th August 2025
📣Don’t miss your chance to be part of the amazing #DRRSC26 meeting.
👉 Click here for further details & registration: bit.ly/46YQZjW
📣Don’t miss your chance to be part of the amazing #DRRSC26 meeting.
👉 Click here for further details & registration: bit.ly/46YQZjW
August 19, 2025 at 12:04 PM
⏰Early Bird and Talk Submission Deadline closing soon - Tuesday 26th August 2025
📣Don’t miss your chance to be part of the amazing #DRRSC26 meeting.
👉 Click here for further details & registration: bit.ly/46YQZjW
📣Don’t miss your chance to be part of the amazing #DRRSC26 meeting.
👉 Click here for further details & registration: bit.ly/46YQZjW
Congratulations to @bcarrick.bsky.social on his Shurl and Kay Curci Fellowship through the Life Sciences Research Foundation! Looking forward to the work to come!
Incredibly honored to be a Shurl and Kay Curci Fellow of the Life Sciences Research Foundation. Thanks to Marv and Judith for their support during my PhD and @lapassmore.bsky.social for her backing and mentorship in my postdoc work.
lsrf.org/current-fell...
lsrf.org/current-fell...
August 1, 2025 at 4:35 PM
Congratulations to @bcarrick.bsky.social on his Shurl and Kay Curci Fellowship through the Life Sciences Research Foundation! Looking forward to the work to come!
Reposted by Lori Passmore
Excited to share our latest work! We found transcription factor SPT6 and phosphorylated Pol II CTD help recruit U1 snRNP to elongating Pol II, allowing efficient co-transcriptional splicing.
Glad to be featured in the Editors’ Highlights!
www.nature.com/articles/s41...
#splicing #cryoEM
Glad to be featured in the Editors’ Highlights!
www.nature.com/articles/s41...
#splicing #cryoEM
July 10, 2025 at 2:29 PM
Excited to share our latest work! We found transcription factor SPT6 and phosphorylated Pol II CTD help recruit U1 snRNP to elongating Pol II, allowing efficient co-transcriptional splicing.
Glad to be featured in the Editors’ Highlights!
www.nature.com/articles/s41...
#splicing #cryoEM
Glad to be featured in the Editors’ Highlights!
www.nature.com/articles/s41...
#splicing #cryoEM
Reposted by Lori Passmore
Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization
Telomerase ribonucleoprotein (RNP) synthesizes telomeric repeats at chromosome ends using a telomerase reverse transcriptase (TERT) and a telomerase RNA (hTR in humans). Previous structural work showe...
www.science.org
July 10, 2025 at 9:26 PM
Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Lori Passmore
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️ tinyurl.com/3yn883b8
July 7, 2025 at 12:08 PM
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️ tinyurl.com/3yn883b8
Reposted by Lori Passmore
Congratulations to LMB Group Leaders Leo James, Greg Jefferis & Marta Zlatic who have been elected Fellows of the @royalsociety.org!
Congratulations also to the #LMBAlumni joining them: John Briggs, Graham Hatfull & Baljit Khakh.
Read more: www2.mrc-lmb.cam.ac.uk/leo-james-gr...
#LMBNews
Congratulations also to the #LMBAlumni joining them: John Briggs, Graham Hatfull & Baljit Khakh.
Read more: www2.mrc-lmb.cam.ac.uk/leo-james-gr...
#LMBNews
May 20, 2025 at 9:09 AM
Congratulations to LMB Group Leaders Leo James, Greg Jefferis & Marta Zlatic who have been elected Fellows of the @royalsociety.org!
Congratulations also to the #LMBAlumni joining them: John Briggs, Graham Hatfull & Baljit Khakh.
Read more: www2.mrc-lmb.cam.ac.uk/leo-james-gr...
#LMBNews
Congratulations also to the #LMBAlumni joining them: John Briggs, Graham Hatfull & Baljit Khakh.
Read more: www2.mrc-lmb.cam.ac.uk/leo-james-gr...
#LMBNews
Reposted by Lori Passmore
Congratulations to the nine outstanding Cambridge scientists who have been elected as Fellows of the @royalsociety.org, the UK’s national academy of sciences and the oldest science academy in continuous existence.
Explore their research 👉 www.cam.ac.uk/research/new...
#CambridgeUniversity
Explore their research 👉 www.cam.ac.uk/research/new...
#CambridgeUniversity
May 20, 2025 at 4:10 PM
Congratulations to the nine outstanding Cambridge scientists who have been elected as Fellows of the @royalsociety.org, the UK’s national academy of sciences and the oldest science academy in continuous existence.
Explore their research 👉 www.cam.ac.uk/research/new...
#CambridgeUniversity
Explore their research 👉 www.cam.ac.uk/research/new...
#CambridgeUniversity
Reposted by Lori Passmore
Come and join us! We’re hiring a new Group Leader in Generative Biology at the @sangerinstitute.bsky.social
Building AI models or the data to train them?
Core funding of >$130M a year for a faculty of ~30.
www.nature.com/naturecareer...
acrobat.adobe.com/id/urn:aaid:...
pls RT!
Building AI models or the data to train them?
Core funding of >$130M a year for a faculty of ~30.
www.nature.com/naturecareer...
acrobat.adobe.com/id/urn:aaid:...
pls RT!
May 6, 2025 at 2:59 PM
Come and join us! We’re hiring a new Group Leader in Generative Biology at the @sangerinstitute.bsky.social
Building AI models or the data to train them?
Core funding of >$130M a year for a faculty of ~30.
www.nature.com/naturecareer...
acrobat.adobe.com/id/urn:aaid:...
pls RT!
Building AI models or the data to train them?
Core funding of >$130M a year for a faculty of ~30.
www.nature.com/naturecareer...
acrobat.adobe.com/id/urn:aaid:...
pls RT!
New work from Matti Turtola showing that mRNA poly(A) tail length is controlled by a kinetic ruler. A real pleasure to work with him!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A kinetic ruler controls mRNA poly(A) tail length
Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs). In the budding ...
www.biorxiv.org
May 2, 2025 at 5:10 PM
New work from Matti Turtola showing that mRNA poly(A) tail length is controlled by a kinetic ruler. A real pleasure to work with him!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
New abstract deadline May 8, 2025. Should be a great meeting!!
REGISTRATION CLOSING SOON! 🚨
#Nucleic25 is fast approaching! Don’t miss your chance to join the conference in sunny Portugal!
Registration Deadline: 10th April 2025
David & Wei can’t wait to see you there! 👉 Click here for more information on how to secure your place: bit.ly/4ckluBE
#Nucleic25 is fast approaching! Don’t miss your chance to join the conference in sunny Portugal!
Registration Deadline: 10th April 2025
David & Wei can’t wait to see you there! 👉 Click here for more information on how to secure your place: bit.ly/4ckluBE
April 18, 2025 at 4:08 PM
New abstract deadline May 8, 2025. Should be a great meeting!!
Canadians 🇨🇦 abroad - you can register to vote in the election! You need to do it soon. www.elections.ca/content2.asp...
Voting by mail – Elections Canada
Apply to vote by mail, Eligible electors can apply to vote by special ballot. With a special ballot, you can vote by mail from anywhere in the world, 2025.
www.elections.ca
April 11, 2025 at 8:51 AM
Canadians 🇨🇦 abroad - you can register to vote in the election! You need to do it soon. www.elections.ca/content2.asp...
Reposted by Lori Passmore
New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
February 25, 2025 at 4:17 PM
New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. www.grc.org/synthetic-le....
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present their research.
Reposted by Lori Passmore
Just a reminder that our tenure track group leader position in the Structural Studies Division of @mrclmb.bsky.social will close in four days!
mrc.tal.net/vx/lang-en-G...
mrc.tal.net/vx/lang-en-G...
Quick Check Needed
mrc.tal.net
March 14, 2025 at 12:25 PM
Just a reminder that our tenure track group leader position in the Structural Studies Division of @mrclmb.bsky.social will close in four days!
mrc.tal.net/vx/lang-en-G...
mrc.tal.net/vx/lang-en-G...