Christa Buecker
@chribue.bsky.social
Molecular Biologist, Transcription enthusiast and stem cell afficionado
Associate Professor at Max Perutz Labs and University Vienna,
Associate Professor at Max Perutz Labs and University Vienna,
Apply!
✨ Passionate about cell biology or biochemistry? Join the Martens Lab as a postdoc to uncover why autophagy stalls at disease-linked protein aggregates - and how to restart it 🧠 Apply here ➡️ tinyurl.com/24dcrcke
November 13, 2025 at 6:23 AM
Apply!
Reposted by Christa Buecker
📣 Paper alert!
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
November 10, 2025 at 11:11 AM
📣 Paper alert!
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today!
journals.biologists.com/dev/article/...
Reposted by Christa Buecker
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Christa Buecker
Congratulations to Irene Schwartz, winner of the @viennabiocenter.bsky.social PhD Award! 🧠👏
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
November 10, 2025 at 8:33 AM
Congratulations to Irene Schwartz, winner of the @viennabiocenter.bsky.social PhD Award! 🧠👏
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Her research reveals how cells fine-tune immune balance through protein degradation 🏆 More ➡️ tinyurl.com/2r9c7a5f
@univie.ac.at
@meduniwien.ac.at
Congratulations, Wendy!
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
November 7, 2025 at 2:44 PM
Congratulations, Wendy!
Reposted by Christa Buecker
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
November 7, 2025 at 11:50 AM
So excited to be funded by @erc.europa.eu to work with this extraordinarily talented group of scientists on the GeneMotors project - unravelling how SMC motors work, how they are regulated and how they regulate gene expression.
@ceesdekker.bsky.social @uoe-igc.bsky.social
@ceesdekker.bsky.social @uoe-igc.bsky.social
Reposted by Christa Buecker
This study presents an in vitro analysis of centriole and cilium formation during early mouse embryonic development, using 3D models to mimic implantation, tissue patterning, and axis elongation. @chribue.bsky.social @isabellavoelkl.bsky.social www.life-science-alliance.org/content/9/1/...
November 6, 2025 at 4:04 PM
This study presents an in vitro analysis of centriole and cilium formation during early mouse embryonic development, using 3D models to mimic implantation, tissue patterning, and axis elongation. @chribue.bsky.social @isabellavoelkl.bsky.social www.life-science-alliance.org/content/9/1/...
Reposted by Christa Buecker
Magnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes.
Read more: www.oeaw.ac.at/gmi/news-eve...
Read more: www.oeaw.ac.at/gmi/news-eve...
November 6, 2025 at 11:08 AM
Magnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes.
Read more: www.oeaw.ac.at/gmi/news-eve...
Read more: www.oeaw.ac.at/gmi/news-eve...
Reposted by Christa Buecker
Mechanism of #autophagy initiation by transmembrane selective autophagy receptors
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
November 6, 2025 at 4:20 PM
Mechanism of #autophagy initiation by transmembrane selective autophagy receptors
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
@elias-adriaenssens.bsky.social & @martenslab.bsky.social review emerging mechanistic differences between soluble and transmembrane autophagy receptors
www.embopress.org/doi/full/10....
Reposted by Christa Buecker
New paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
November 6, 2025 at 4:04 PM
New paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
@imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
Congratulation, @martenslab.bsky.social! great colleague and awesome scientist, now with his third ERC grant!
Big news! Group leader Sascha Martens has been awarded a prestigious @erc.europa.eu Synergy Grant for the collaborative project DegrAbility to explore how cells can better recycle harmful protein aggregates linked to diseases like Alzheimer’s ➡️ tinyurl.com/2zuz9jcf
@univie.ac.at
@meduniwien.ac.at
@univie.ac.at
@meduniwien.ac.at
November 6, 2025 at 3:39 PM
Congratulation, @martenslab.bsky.social! great colleague and awesome scientist, now with his third ERC grant!
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 6, 2025 at 4:35 AM
And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu
October 31, 2025 at 9:25 AM
Reposted by Christa Buecker
Our latest review is now online! 👇
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
October 31, 2025 at 6:24 AM
Our latest review is now online! 👇
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
@martenslab.bsky.social
Mechanism of autophagy initiation by transmembrane selective autophagy receptors | The EMBO Journal www.embopress.org/doi/full/10....
Reposted by Christa Buecker
This exciting study by the Buecker lab @chribue.bsky.social & first author Isabella Voelkl @isabellavoelkl.bsky.social explores in vitro differentiation models for their usability in studying cilia and centriole formation in mouse embryonic development www.life-science-alliance.org/content/9/1/...
October 30, 2025 at 3:05 PM
This exciting study by the Buecker lab @chribue.bsky.social & first author Isabella Voelkl @isabellavoelkl.bsky.social explores in vitro differentiation models for their usability in studying cilia and centriole formation in mouse embryonic development www.life-science-alliance.org/content/9/1/...
Reposted by Christa Buecker
I’m deeply grateful to my supervisor @chribue.bsky.social, Alexander Dammermann, Martin Leeb and all colleagues and collaborators for their support throughout this journey. Thank you @vbcscitraining.bsky.social and @maxperutzlabs.ac.at for providing such a stimulating scientific environment.
October 30, 2025 at 9:34 AM
I’m deeply grateful to my supervisor @chribue.bsky.social, Alexander Dammermann, Martin Leeb and all colleagues and collaborators for their support throughout this journey. Thank you @vbcscitraining.bsky.social and @maxperutzlabs.ac.at for providing such a stimulating scientific environment.
Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.
In vitro approaches to study centriole and cilium function in early mouse embryogenesis
Although centrioles and primary cilia play an essential role in early mammalian development, their specific function during the interval between their initial formation and the subsequent arrest of em...
www.life-science-alliance.org
October 30, 2025 at 9:17 AM
Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.
Reposted by Christa Buecker
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
October 27, 2025 at 11:49 AM
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
On my way back from @cshasia.bsky.social meeting on Systems Biology of Gene Regulation. It was fabulous! Small but powerful, fantastic talks and really showcasing the fantastic and impressive science going on in China.
October 25, 2025 at 12:59 AM
On my way back from @cshasia.bsky.social meeting on Systems Biology of Gene Regulation. It was fabulous! Small but powerful, fantastic talks and really showcasing the fantastic and impressive science going on in China.
super cool to see this out! looking forward to now read the details! Congratulations, Yad and @mmasoura.bsky.social
Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one?
Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...
Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...
Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
www.biorxiv.org
October 16, 2025 at 6:31 PM
super cool to see this out! looking forward to now read the details! Congratulations, Yad and @mmasoura.bsky.social
Reposted by Christa Buecker
RNA biology is a major research focus at the Perutz - and the new @fwf-at.bsky.social grants strengthen it even further 🙌 Elif Karagöz and Pavel Kovarik will investigate how RNA-binding proteins regulate cellular stress and immune responses ➡️ tinyurl.com/2s3f3mu8
@univie.ac.at
@meduniwien.ac.at
@univie.ac.at
@meduniwien.ac.at
October 16, 2025 at 2:09 PM
RNA biology is a major research focus at the Perutz - and the new @fwf-at.bsky.social grants strengthen it even further 🙌 Elif Karagöz and Pavel Kovarik will investigate how RNA-binding proteins regulate cellular stress and immune responses ➡️ tinyurl.com/2s3f3mu8
@univie.ac.at
@meduniwien.ac.at
@univie.ac.at
@meduniwien.ac.at
Yay! Congratulations @blanka-majchrzycka.bsky.social and @danielibrahim.bsky.social ! Good to see this beautiful dissection out !
What is a promoter? And how does it work?
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
We very happy to share our latest work trying to understand enhancer-promoter compatibility.
I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters
www.biorxiv.org/content/10.1...
Enhancer-promoter compatibility is mediated by the promoter-proximal region
Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...
www.biorxiv.org
October 16, 2025 at 4:34 PM
Yay! Congratulations @blanka-majchrzycka.bsky.social and @danielibrahim.bsky.social ! Good to see this beautiful dissection out !
Reposted by Christa Buecker
The #CSHA meeting on Systems Biology of Gene Regulation & Genome Editing kicks off next Monday! ⏳ Don’t miss your shot to dive into cutting-edge science. 👉 Check out the full program and register now on www.csh-asia.org?content/2767
Location: Suzhou. China | Oct.20-24, 2025
Location: Suzhou. China | Oct.20-24, 2025
October 16, 2025 at 2:23 AM
The #CSHA meeting on Systems Biology of Gene Regulation & Genome Editing kicks off next Monday! ⏳ Don’t miss your shot to dive into cutting-edge science. 👉 Check out the full program and register now on www.csh-asia.org?content/2767
Location: Suzhou. China | Oct.20-24, 2025
Location: Suzhou. China | Oct.20-24, 2025
Reposted by Christa Buecker
If you’re interested in a PhD that explores the ins and outs of genomes and the nucleus - don’t look further but apply here!!!
It is excellent 👌
It is excellent 👌
🚨 Please share! We are seeking motivated PhD students who wish to work at the intersection of molecular life sciences and computational sciences.
#IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Check out our projects and apply by Jan 7th, 2026!
www.molgen.mpg.de/IMPRSPhDproj...
#IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Check out our projects and apply by Jan 7th, 2026!
www.molgen.mpg.de/IMPRSPhDproj...
October 9, 2025 at 12:49 PM
If you’re interested in a PhD that explores the ins and outs of genomes and the nucleus - don’t look further but apply here!!!
It is excellent 👌
It is excellent 👌