Lopes_Lab
@lopeslab.bsky.social
We use molecular & cell biology and single-molecule approaches to study DNA replication stress and its contribution to genome instability in cancer.
Happy to have contributed to this interesting study from penengolab.bsky.social! another interesting example of how chromatin modifications and their readers orchestrate replication fork plasticity and protection 👏👇
H2B ubiquitination by RNF20/40 safeguards replication fork dynamics in human cells, by facilitating fork reversal and recruiting RNF169 that protects from excessive degradation of nascent DNA
@penengolab.bsky.social and collaborators
www.embopress.org/doi/full/10....
@penengolab.bsky.social and collaborators
www.embopress.org/doi/full/10....
October 30, 2025 at 1:19 PM
Happy to have contributed to this interesting study from penengolab.bsky.social! another interesting example of how chromatin modifications and their readers orchestrate replication fork plasticity and protection 👏👇
One more opportunity in a few days (Nov 4th), to attend two great 30' talks online! 👇
October 29, 2025 at 1:12 PM
One more opportunity in a few days (Nov 4th), to attend two great 30' talks online! 👇
New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application 👍 👇
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch
September 11, 2025 at 7:58 PM
New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application 👍 👇
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
Tomorrow (Tue 9th) at 5 PM CET. Don't miss it!
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! 👇
September 8, 2025 at 10:52 PM
Tomorrow (Tue 9th) at 5 PM CET. Don't miss it!
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! 👇
August 20, 2025 at 2:09 PM
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! 👇
One more appointment with great science in a few days, one click away 👇
May 28, 2025 at 7:55 PM
One more appointment with great science in a few days, one click away 👇
Exciting PhD project available in our lab (time sensitive)! 👇
May 7, 2025 at 12:10 PM
Exciting PhD project available in our lab (time sensitive)! 👇
Exciting science ahead! Hope to see many of you online on Tuesday 6th (just connect, no registration needed)
The Genome Integrity Webinar Series continues on Tuesday, May 6th at 5PM (Rome) / 11AM (New York) with an exciting discussion on DNA damage response and repair @kajastelab.bsky.social
Join via Zoom: uniroma1.zoom.us/j/95149984403
Join via Zoom: uniroma1.zoom.us/j/95149984403
May 1, 2025 at 2:50 PM
Exciting science ahead! Hope to see many of you online on Tuesday 6th (just connect, no registration needed)
More exciting genome integrity research at the horizon. Register to receive alerts and marks for your calendar 👍👇
We thank @martakova.bsky.social and Mate Maus for sharing their research with our community at yesterday's seminar!
Our next seminar on Tuesday, May 6th will feature @kajastelab.bsky.social and Raphael Ceccaldi.
Subscribe here to receive the reminder: t.co/Hv6iLmjlly
Our next seminar on Tuesday, May 6th will feature @kajastelab.bsky.social and Raphael Ceccaldi.
Subscribe here to receive the reminder: t.co/Hv6iLmjlly
April 2, 2025 at 9:25 PM
More exciting genome integrity research at the horizon. Register to receive alerts and marks for your calendar 👍👇
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇
March 17, 2025 at 9:58 PM
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇
Just landed back in the lab, after a few incredible days on the Alps! A wonderful opportunity to consolidate our projects, rethink our strategies, explore new ideas, blend as a team... and, above all, have a lot of fun! Proud of you guys... and certainly much stronger now! 👍🤩
February 3, 2025 at 11:00 PM
Just landed back in the lab, after a few incredible days on the Alps! A wonderful opportunity to consolidate our projects, rethink our strategies, explore new ideas, blend as a team... and, above all, have a lot of fun! Proud of you guys... and certainly much stronger now! 👍🤩
a great conference, and a tribute to a great scientist and man 👇
Dear Colleagues,
We are extending our early bird registration deadline to December 17th as there have been some issues both with the Carte Achat service as well as with the website. All have now been sorted.We look forward to seeing you for this special event that will honour the memory of Angelos.
We are extending our early bird registration deadline to December 17th as there have been some issues both with the Carte Achat service as well as with the website. All have now been sorted.We look forward to seeing you for this special event that will honour the memory of Angelos.
January 19, 2025 at 10:58 PM
a great conference, and a tribute to a great scientist and man 👇
Landing on Bluesky by sharing the latest preprint from the lab: nucleoplasmic Lamin A/C modulates RECQ1-mediated fork restart upon mild genotoxic stress, by regulating heterochromatin marks and ADP-ribosylation levels at replication factories
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels
Mild replication interference is a consolidated strategy for cancer chemotherapy. Tolerance to mild replication stress (RS) relies on active fork slowing, mediated by transient fork reversal and RECQ1...
www.biorxiv.org
January 19, 2025 at 12:01 PM
Landing on Bluesky by sharing the latest preprint from the lab: nucleoplasmic Lamin A/C modulates RECQ1-mediated fork restart upon mild genotoxic stress, by regulating heterochromatin marks and ADP-ribosylation levels at replication factories
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...