Lopes_Lab
@lopeslab.bsky.social
We use molecular & cell biology and single-molecule approaches to study DNA replication stress and its contribution to genome instability in cancer.
Tomorrow (Tue 3rd)!
PLEASE NOTE THE ALTERNATIVE ZOOM LINK! π
PLEASE NOTE THE ALTERNATIVE ZOOM LINK! π
February 2, 2026 at 8:59 PM
Tomorrow (Tue 3rd)!
PLEASE NOTE THE ALTERNATIVE ZOOM LINK! π
PLEASE NOTE THE ALTERNATIVE ZOOM LINK! π
Don't miss the opportunity to attend exciting virtual talks from leading scientists in genome integrity, provided by the @genomeiinetwork.bsky.social! Next one is in a few days π
Another great science appointment is coming up with
@nitikataneja.bsky.social and @doksanilab.bsky.social!
Join us live on Tuesday, February 3rd at 5pm (Rome) / 11am (NYC).
Zoom link: uniroma1.zoom.us/j/95149984403
Register here to stay in the loop: docs.google.com/forms/d/e/1F...
@nitikataneja.bsky.social and @doksanilab.bsky.social!
Join us live on Tuesday, February 3rd at 5pm (Rome) / 11am (NYC).
Zoom link: uniroma1.zoom.us/j/95149984403
Register here to stay in the loop: docs.google.com/forms/d/e/1F...
January 29, 2026 at 10:37 PM
Don't miss the opportunity to attend exciting virtual talks from leading scientists in genome integrity, provided by the @genomeiinetwork.bsky.social! Next one is in a few days π
Happy to have contributed to this interesting story. Cool experimental system and thought-provoking findings π
January 17, 2026 at 6:06 AM
Happy to have contributed to this interesting story. Cool experimental system and thought-provoking findings π
TODAY! π
One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link π
January 13, 2026 at 7:42 AM
TODAY! π
One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link π
January 8, 2026 at 3:47 PM
One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link π
We link replication fork plasticity to another important player of nuclear architecture, i.e. Lamin A/C, by showing that its nucleoplasmic fraction modulates heterochromatic marks and ADP ribosylation levels at replication factories, thereby controlling RECQ1-dependent restart of reversed forks!
December 19, 2025 at 12:44 PM
We link replication fork plasticity to another important player of nuclear architecture, i.e. Lamin A/C, by showing that its nucleoplasmic fraction modulates heterochromatic marks and ADP ribosylation levels at replication factories, thereby controlling RECQ1-dependent restart of reversed forks!
Thrilled to share our latest work - now available in full in Nature Communications - led in my lab by @vcherdy.bsky.social, with key collaborative contributions from @nitikataneja.bsky.social .
rdcu.be/eVrxX
rdcu.be/eVrxX
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels
Nature Communications - Replication fork plasticity upon genotoxic stress is modulated by nuclear architectural components by elusive mechanisms. Here the authors implicate Lamin A/C β best...
rdcu.be
December 19, 2025 at 12:44 PM
Thrilled to share our latest work - now available in full in Nature Communications - led in my lab by @vcherdy.bsky.social, with key collaborative contributions from @nitikataneja.bsky.social .
rdcu.be/eVrxX
rdcu.be/eVrxX
TODAY! Donβt miss it! π
In a few days we'll have our last appointment (for this year) with great virtual talks via the GiiN. Please note in agenda and join us with a click! π
December 2, 2025 at 7:29 AM
TODAY! Donβt miss it! π
We will be collecting applications for one more week (Dec 5th), then proceed shortlisting candidates for the next βSNSF starting grantβ deadline (May 2026).
Please hurry up sending your docs and/or spread the news! (β¦and mind the βSwiss linkβ in the eligibility criteria) π
Please hurry up sending your docs and/or spread the news! (β¦and mind the βSwiss linkβ in the eligibility criteria) π
New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application π π
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch
November 29, 2025 at 1:05 AM
We will be collecting applications for one more week (Dec 5th), then proceed shortlisting candidates for the next βSNSF starting grantβ deadline (May 2026).
Please hurry up sending your docs and/or spread the news! (β¦and mind the βSwiss linkβ in the eligibility criteria) π
Please hurry up sending your docs and/or spread the news! (β¦and mind the βSwiss linkβ in the eligibility criteria) π
In a few days we'll have our last appointment (for this year) with great virtual talks via the GiiN. Please note in agenda and join us with a click! π
November 27, 2025 at 7:46 AM
In a few days we'll have our last appointment (for this year) with great virtual talks via the GiiN. Please note in agenda and join us with a click! π
Happy to have contributed to this interesting study from penengolab.bsky.social! another interesting example of how chromatin modifications and their readers orchestrate replication fork plasticity and protection ππ
H2B ubiquitination by RNF20/40 safeguards replication fork dynamics in human cells, by facilitating fork reversal and recruiting RNF169 that protects from excessive degradation of nascent DNA
@penengolab.bsky.social and collaborators
www.embopress.org/doi/full/10....
@penengolab.bsky.social and collaborators
www.embopress.org/doi/full/10....
October 30, 2025 at 1:19 PM
Happy to have contributed to this interesting study from penengolab.bsky.social! another interesting example of how chromatin modifications and their readers orchestrate replication fork plasticity and protection ππ
One more opportunity in a few days (Nov 4th), to attend two great 30' talks online! π
October 29, 2025 at 1:12 PM
One more opportunity in a few days (Nov 4th), to attend two great 30' talks online! π
New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application π π
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch
September 11, 2025 at 7:58 PM
New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application π π
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
www.imcr.uzh.ch/dam/jcr:3d1f...
www.imcr.uzh.ch/en.html
Tomorrow (Tue 9th) at 5 PM CET. Don't miss it!
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! π
September 8, 2025 at 10:52 PM
Tomorrow (Tue 9th) at 5 PM CET. Don't miss it!
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! π
August 20, 2025 at 2:09 PM
Mark your calendar (September 9th) for two more exciting virtual seminars of the Genome Integrity Italian Network (GiiN). Full schedule for the Fall season also provided just below. No registration required, just come and join us with a click! π
One more appointment with great science in a few days, one click away π
May 28, 2025 at 7:55 PM
One more appointment with great science in a few days, one click away π
Exciting PhD project available in our lab (time sensitive)! π
May 7, 2025 at 12:10 PM
Exciting PhD project available in our lab (time sensitive)! π
Exciting science ahead! Hope to see many of you online on Tuesday 6th (just connect, no registration needed)
The Genome Integrity Webinar Series continues on Tuesday, May 6th at 5PM (Rome) / 11AM (New York) with an exciting discussion on DNA damage response and repair @kajastelab.bsky.social
Join via Zoom: uniroma1.zoom.us/j/95149984403
Join via Zoom: uniroma1.zoom.us/j/95149984403
May 1, 2025 at 2:50 PM
Exciting science ahead! Hope to see many of you online on Tuesday 6th (just connect, no registration needed)
More exciting genome integrity research at the horizon. Register to receive alerts and marks for your calendar ππ
We thank @martakova.bsky.social and Mate Maus for sharing their research with our community at yesterday's seminar!
Our next seminar on Tuesday, May 6th will feature @kajastelab.bsky.social and Raphael Ceccaldi.
Subscribe here to receive the reminder: t.co/Hv6iLmjlly
Our next seminar on Tuesday, May 6th will feature @kajastelab.bsky.social and Raphael Ceccaldi.
Subscribe here to receive the reminder: t.co/Hv6iLmjlly
April 2, 2025 at 9:25 PM
More exciting genome integrity research at the horizon. Register to receive alerts and marks for your calendar ππ
yes, Zoom link (and QR code to register for e-mail alerts) are in the flyers π
March 18, 2025 at 8:58 AM
yes, Zoom link (and QR code to register for e-mail alerts) are in the flyers π
Andre Nussenzweig, Michele Pagano, @polosophie.bsky.social Evi Soutoglou, @nitikataneja.bsky.social Marco Tigano, @rubenvanboxtel.bsky.social. Chairs: @lopeslab.bsky.social @dimiccolab.bsky.social Hope to see many of you frequently online!
March 17, 2025 at 11:13 PM
Andre Nussenzweig, Michele Pagano, @polosophie.bsky.social Evi Soutoglou, @nitikataneja.bsky.social Marco Tigano, @rubenvanboxtel.bsky.social. Chairs: @lopeslab.bsky.social @dimiccolab.bsky.social Hope to see many of you frequently online!
@alebrambati.bsky.social @cantorlab.bsky.social Raphael Ceccaldi @chowdhurylab.bsky.social @albertociccia.bsky.social Diego Dibitetto, @agagambus.bsky.social @kajastelab.bsky.social @peterlylab.bsky.social @martakova.bsky.social @fmattiroli.bsky.social Mate Maus @centromellone.bsky.social
March 17, 2025 at 11:11 PM
Andre Nussenzweig, Michele Pagano, #polosophie.bsky.social Evi Soutoglou, #nitikataneja.bsky.social Marco Tigano, #rubenvanboxtel.bsky.social. Chairs: #lopeslab.bsky.social #dimiccolab.bsky.social Hope to see many of you frequently online!
March 17, 2025 at 9:58 PM
Andre Nussenzweig, Michele Pagano, #polosophie.bsky.social Evi Soutoglou, #nitikataneja.bsky.social Marco Tigano, #rubenvanboxtel.bsky.social. Chairs: #lopeslab.bsky.social #dimiccolab.bsky.social Hope to see many of you frequently online!
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30β), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!π
March 17, 2025 at 9:58 PM
Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30β), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!π