Reposted by haysamrady
#nephsky
Organ donation and subsequent hydroceles
Organ donation and subsequent hydroceles
NEW: 1 in 8 men undergo scrotal surgery 20 years after kidney donation, underscoring the need for increased patient education about the risks and symptoms to monitor after donation. https://f.mtr.cool/xpxelntcyw
November 11, 2025 at 9:20 PM
#nephsky
Organ donation and subsequent hydroceles
Organ donation and subsequent hydroceles
Reposted by haysamrady
Podocyte injury and loss are key events in the progression of chronic kidney disease.
This issue’s cover features work by Ika N. Kadariswantiningsih et al. on the selective upregulation of CCL5 in podocytes during human glomerular diseases.
insight.jci.org/articles/vie...
This issue’s cover features work by Ika N. Kadariswantiningsih et al. on the selective upregulation of CCL5 in podocytes during human glomerular diseases.
insight.jci.org/articles/vie...
November 10, 2025 at 5:15 PM
Podocyte injury and loss are key events in the progression of chronic kidney disease.
This issue’s cover features work by Ika N. Kadariswantiningsih et al. on the selective upregulation of CCL5 in podocytes during human glomerular diseases.
insight.jci.org/articles/vie...
This issue’s cover features work by Ika N. Kadariswantiningsih et al. on the selective upregulation of CCL5 in podocytes during human glomerular diseases.
insight.jci.org/articles/vie...
Reposted by haysamrady
This image is from a biopsy of a young female who presented with proteinuria during pregnancy. Routine immunofluorescence was negative. What is this stain and what is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
November 10, 2025 at 1:50 PM
This image is from a biopsy of a young female who presented with proteinuria during pregnancy. Routine immunofluorescence was negative. What is this stain and what is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
Reposted by haysamrady
As one of the original flozinators it so maddening to see nephrologists flozinate *instead* of using immunosuppresants, dz modifying therapies in nonDM CKD. Consider a thought experiment in transplant: proteinuria is often how we pick up ABMR & an SGLT2i is the wrong answer. Now do IgAN, SLE,C3G etc
November 10, 2025 at 2:18 PM
As one of the original flozinators it so maddening to see nephrologists flozinate *instead* of using immunosuppresants, dz modifying therapies in nonDM CKD. Consider a thought experiment in transplant: proteinuria is often how we pick up ABMR & an SGLT2i is the wrong answer. Now do IgAN, SLE,C3G etc
Reposted by haysamrady
A genetic mutation associated with congenital heart disease has also been shown to cause early kidney damage, highlighting the importance of early screening and intervention in affected children. doi.org/g99wkj
Congenital heart disease mutation linked to kidney damage
Biomedical engineers at Duke University have shown that a genetic mutation that causes congenital heart disease also contributes to kidney damage and developmental defects.
medicalxpress.com
November 10, 2025 at 2:30 PM
A genetic mutation associated with congenital heart disease has also been shown to cause early kidney damage, highlighting the importance of early screening and intervention in affected children. doi.org/g99wkj
Reposted by haysamrady
AI in Healthcare
@asakhuja.bsky.social gave an excellent overview of what this entails, the opportunities and its limitations
youtu.be/0qOaoGncKHw?...
#NephGR #NephSky
@asakhuja.bsky.social gave an excellent overview of what this entails, the opportunities and its limitations
youtu.be/0qOaoGncKHw?...
#NephGR #NephSky
AI in Healthcare with Dr Ankit Sakhuja
YouTube video by Ottawa Nephrology
youtu.be
November 10, 2025 at 12:03 PM
AI in Healthcare
@asakhuja.bsky.social gave an excellent overview of what this entails, the opportunities and its limitations
youtu.be/0qOaoGncKHw?...
#NephGR #NephSky
@asakhuja.bsky.social gave an excellent overview of what this entails, the opportunities and its limitations
youtu.be/0qOaoGncKHw?...
#NephGR #NephSky
Reposted by haysamrady
Nothing works in dialysis - except fis oil. Truly amazing data from the PISCES. Should we begin perscribimg fish oil supplements to all our dialysis patients? In spite of my somewhat sceptical priors, I think the answer should be “yes” #NephSky #KidneyWk #nephrology
November 9, 2025 at 11:26 AM
Nothing works in dialysis - except fis oil. Truly amazing data from the PISCES. Should we begin perscribimg fish oil supplements to all our dialysis patients? In spite of my somewhat sceptical priors, I think the answer should be “yes” #NephSky #KidneyWk #nephrology
Reposted by haysamrady
Ian McCoy describing higher rates of intradialytic hypotension with more frequent HD in AKI-D including the fresh off the press LIBERATE-D. #kidneywk
November 8, 2025 at 5:14 PM
Ian McCoy describing higher rates of intradialytic hypotension with more frequent HD in AKI-D including the fresh off the press LIBERATE-D. #kidneywk
Reposted by haysamrady
From 2011 to 2020, chronic kidney disease affected 14.6% of US adults and 16.7% with cardiometabolic conditions, yet only 13% were aware of their diagnosis; awareness was lowest in younger adults, women, and Hispanic adults.
#AHA25 @ahascience.bsky.social
ja.ma/4hXARmk
#AHA25 @ahascience.bsky.social
ja.ma/4hXARmk
November 8, 2025 at 8:10 PM
From 2011 to 2020, chronic kidney disease affected 14.6% of US adults and 16.7% with cardiometabolic conditions, yet only 13% were aware of their diagnosis; awareness was lowest in younger adults, women, and Hispanic adults.
#AHA25 @ahascience.bsky.social
ja.ma/4hXARmk
#AHA25 @ahascience.bsky.social
ja.ma/4hXARmk
Reposted by haysamrady
💬 Invited Commentary: Chronic kidney disease (#CKD) amplifies cardiovascular risk, yet therapeutic inertia and low disease awareness persist.
New CKM syndrome data reveal persistently low CKD recognition.
#AHA25 @ahascience.bsky.social
ja.ma/4otDIWj
New CKM syndrome data reveal persistently low CKD recognition.
#AHA25 @ahascience.bsky.social
ja.ma/4otDIWj
November 8, 2025 at 8:15 PM
💬 Invited Commentary: Chronic kidney disease (#CKD) amplifies cardiovascular risk, yet therapeutic inertia and low disease awareness persist.
New CKM syndrome data reveal persistently low CKD recognition.
#AHA25 @ahascience.bsky.social
ja.ma/4otDIWj
New CKM syndrome data reveal persistently low CKD recognition.
#AHA25 @ahascience.bsky.social
ja.ma/4otDIWj
Reposted by haysamrady
Reposted by haysamrady
Late breakers that included children:
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
✅Setanaxib in Alport (12+)
Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk
November 8, 2025 at 10:29 PM
Reposted by haysamrady
Summary from the #NephJC team of day 3
www.nephjc.com/news/2025/11...
Since we had only two trials simul-published today at #KidneyWk we took some creative license on what to include !
@nephroseeker.medsky.social with the beautiful graphics and tables apart from the lion’s share of writing!
www.nephjc.com/news/2025/11...
Since we had only two trials simul-published today at #KidneyWk we took some creative license on what to include !
@nephroseeker.medsky.social with the beautiful graphics and tables apart from the lion’s share of writing!
Kidney Week in Houston: Day 3 — NephJC
Day 3 of Kidney Week. Sibeprenlimab and Balcinrenone on NEJM and Lancet, plus a couple of other non-kidneywk studies,
www.nephjc.com
November 9, 2025 at 4:28 AM
Summary from the #NephJC team of day 3
www.nephjc.com/news/2025/11...
Since we had only two trials simul-published today at #KidneyWk we took some creative license on what to include !
@nephroseeker.medsky.social with the beautiful graphics and tables apart from the lion’s share of writing!
www.nephjc.com/news/2025/11...
Since we had only two trials simul-published today at #KidneyWk we took some creative license on what to include !
@nephroseeker.medsky.social with the beautiful graphics and tables apart from the lion’s share of writing!
Reposted by haysamrady
November 8, 2025 at 5:21 PM
Reposted by haysamrady
Dietary potassium can be good for you.
AND there is little to no correlation btwn dietary K intake & serum K level (even in pts w/ CKD).
#Kidneywk
AND there is little to no correlation btwn dietary K intake & serum K level (even in pts w/ CKD).
#Kidneywk
November 8, 2025 at 6:21 PM
Dietary potassium can be good for you.
AND there is little to no correlation btwn dietary K intake & serum K level (even in pts w/ CKD).
#Kidneywk
AND there is little to no correlation btwn dietary K intake & serum K level (even in pts w/ CKD).
#Kidneywk
Reposted by haysamrady
Busting some delusions about #longcovid
open.substack.com/pub/christos...
(Also on X/Twitter and Mastodon)
open.substack.com/pub/christos...
(Also on X/Twitter and Mastodon)
Busting delusions about long covid
This will come out as a subtweet and yes dear reader it is.
open.substack.com
November 8, 2025 at 6:30 PM
Busting some delusions about #longcovid
open.substack.com/pub/christos...
(Also on X/Twitter and Mastodon)
open.substack.com/pub/christos...
(Also on X/Twitter and Mastodon)
Reposted by haysamrady
Which antihypertensive agents should be used in Thoracic Aorta Dissection?
🔗 academic.oup.com/ajh/advance-...
#WeekendReads from the Advance Articles section
🔗 academic.oup.com/ajh/advance-...
#WeekendReads from the Advance Articles section
Hypertension in Thoracic Aortic Dissection: A Meta-Analysis-Based Considerations in the Choice of Antihypertensive Agents
AbstractBACKGROUND. Thoracic aortic dissection (TAD) is a potentially fatal condition. It has been linked with hypertension, and guidelines recommend antih
academic.oup.com
November 8, 2025 at 11:30 AM
Which antihypertensive agents should be used in Thoracic Aorta Dissection?
🔗 academic.oup.com/ajh/advance-...
#WeekendReads from the Advance Articles section
🔗 academic.oup.com/ajh/advance-...
#WeekendReads from the Advance Articles section
Reposted by haysamrady
Indications for mineralocorticoid receptor antagonists (MRAs) in the management of cardio-kidney risk
#KidneyWk #Nephpearls #NephSky #Cardiorenal
✅ Check out this resource from @theisn.org
@isnkidneycare.bsky.social
👉 www.theisn.org/initiatives/...
#KidneyWk #Nephpearls #NephSky #Cardiorenal
✅ Check out this resource from @theisn.org
@isnkidneycare.bsky.social
👉 www.theisn.org/initiatives/...
November 8, 2025 at 12:46 PM
Indications for mineralocorticoid receptor antagonists (MRAs) in the management of cardio-kidney risk
#KidneyWk #Nephpearls #NephSky #Cardiorenal
✅ Check out this resource from @theisn.org
@isnkidneycare.bsky.social
👉 www.theisn.org/initiatives/...
#KidneyWk #Nephpearls #NephSky #Cardiorenal
✅ Check out this resource from @theisn.org
@isnkidneycare.bsky.social
👉 www.theisn.org/initiatives/...
Reposted by haysamrady
Missing all the overwhelming amount of science coming out of #KidneyWk?
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
Kidney Week in Houston: Day 2 — NephJC
in this edition: Fish Oil, GBD, Flozination meta-analysis, CHW intervention in Hispanic/Latino patients, and much more
www.nephjc.com
November 8, 2025 at 2:06 PM
Missing all the overwhelming amount of science coming out of #KidneyWk?
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
The #NephJC crew has got you covered
Day 2 edition www.nephjc.com/news/kidneyw... via @nephroseeker.medsky.social & moi
Reposted by haysamrady
And in the evening
- a CAR T in refractory SLE
- a PKD trial
- increasing PD in Vets
- Povetacicept in IgA
- TESTING Longterm term data
- what do the AHA/ACC BP guidelines mean?
#KidneyWk
- a CAR T in refractory SLE
- a PKD trial
- increasing PD in Vets
- Povetacicept in IgA
- TESTING Longterm term data
- what do the AHA/ACC BP guidelines mean?
#KidneyWk
November 8, 2025 at 2:11 PM
And in the evening
- a CAR T in refractory SLE
- a PKD trial
- increasing PD in Vets
- Povetacicept in IgA
- TESTING Longterm term data
- what do the AHA/ACC BP guidelines mean?
#KidneyWk
- a CAR T in refractory SLE
- a PKD trial
- increasing PD in Vets
- Povetacicept in IgA
- TESTING Longterm term data
- what do the AHA/ACC BP guidelines mean?
#KidneyWk
Reposted by haysamrady
Today’s LBCTs and late breaking science!
Morning:
- an Alport trial!
- Telitacicept
- REGENCY biopsy data
- Vitamin R updated in Membranous
- another sibeprenlimab slice
- Balcinrenine + Dapa in CKD
#KidneyWk
Morning:
- an Alport trial!
- Telitacicept
- REGENCY biopsy data
- Vitamin R updated in Membranous
- another sibeprenlimab slice
- Balcinrenine + Dapa in CKD
#KidneyWk
November 8, 2025 at 2:11 PM
Today’s LBCTs and late breaking science!
Morning:
- an Alport trial!
- Telitacicept
- REGENCY biopsy data
- Vitamin R updated in Membranous
- another sibeprenlimab slice
- Balcinrenine + Dapa in CKD
#KidneyWk
Morning:
- an Alport trial!
- Telitacicept
- REGENCY biopsy data
- Vitamin R updated in Membranous
- another sibeprenlimab slice
- Balcinrenine + Dapa in CKD
#KidneyWk
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles
#nephrology #nephsky
link.springer.com/article/10.1...
#nephrology #nephsky
link.springer.com/article/10.1...
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles - Pediatric Nephrology
Background Rituximab is considered a therapeutic option in children with refractory nephrotic syndrome (RNS). However, the efficacy and safety of rituximab treatment remain unclear. Objective This stu...
link.springer.com
November 8, 2025 at 2:48 PM
Rituximab in pediatric refractory nephrotic syndrome: a systematic review and meta-analysis evaluating therapeutic efficacy and adverse event profiles
#nephrology #nephsky
link.springer.com/article/10.1...
#nephrology #nephsky
link.springer.com/article/10.1...
Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism
#nephsky #nephrology
www.frontiersin.org/journals/end...
#nephsky #nephrology
www.frontiersin.org/journals/end...
Frontiers | Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism
Aims/hypothesisSodium–glucose cotransporter 2 inhibitors (SGLT2i) confer cardio-renal protection, and recent work implicates enhanced branched-chain amino ac...
www.frontiersin.org
November 8, 2025 at 6:22 AM
Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism
#nephsky #nephrology
www.frontiersin.org/journals/end...
#nephsky #nephrology
www.frontiersin.org/journals/end...
Reposted by haysamrady
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.
November 7, 2025 at 4:43 PM
Flashback #FluorescenceFriday to some of the first light-sheet imaging we were doing. Video shows the collecting duct system of the developing kidney labeled with a pan-cytokeratin antibody. Courtesy of former talented technician Deanna Hardesty.