Persistent chronic hypotension (PCH) is a debilitating condition in patients undergoing long-term hemodialysis that is often deemed a relative contrai…

More than half of people with advanced kidney disease develop cardiovascular problems. A new study finds that diseased kidneys release tiny particles that are toxic to the heart.

Subclavian artery (SA) stenosis is an uncommon but important cause of arteriovenous fistula (AVF) dysfunction in hemodialysis patients, yet its diagnosis is frequently delayed because symptoms are nonspecific and often attributed to venous lesions. We report a case series of nine hemodialysis patien …

An experimental drug compound could be a promising treatment for harmful diabetes complications, per a new study in lab mice and human cells.

Light chain proximal tubulopathy (LCPT) is a rare kidney disorder associated with monoclonal gammopathy, traditionally defined by crystalline inclusions in proximal tubular epithelial cells. A poorly ...

By Benjamin Boettner (BOSTON) — The human kidney filters about a cup of blood every minute, removing waste, excess fluid, and toxins from it, while also regulating blood pressure, balancing important ...

The loss of proteins into the urine (proteinuria) is an important risk factor for renal and cardiovascular disease. In particular, albuminuria is associated with an increased risk of chronic kidney di...

We read with great interest the article by Andeen et al.1 on Bartonella endocarditis–associated glomerulonephritis as a mimicker of autoimmunity and vasculitis. Although antineutrophil cytoplasmic aut...

BMC Nephrology - Preoperative occult renal dysfunction (PORD), defined as a normal serum creatinine (Scr) level with glomerular filtration rate (eGFR) < 60...

Epigenetic regulation through histone modifications plays a crucial role in driving cellular state transitions. Regulating gene transcription through bivalency, the co-occurrence of activating histone...

In a new study published in Kidney International, researchers report that drugs known as SGLT2 inhibitors prevented age-related deterioration of kidney structure and function in the African turquoise killifish, a vertebrate that completes its entire lifespan in just a few months. The findings reveal specific biological mechanisms that may help explain why these drugs consistently protect kidney and cardiovascular health in people, beyond their original role in lowering blood sugar.

This review discusses the pathophysiology, epidemiology, clinical presentation, diagnosis, treatment, and prognosis of primary IgA nephropathy (IgAN) in adults, with a focus on treatment recommendati...

In an unexpected finding, a UCLA-led team has discovered that bacteria are present inside the most common type of kidney stone, revealing a previously unrecognized component involved in their formation.

This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.