JAMA Cardiology
@jamacardiology.com
JAMA Cardiology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
🌐 JAMACardiology.com
🌐 JAMACardiology.com
The numbers are in.
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/49sdM8w
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/49sdM8w
December 25, 2025 at 12:00 PM
The numbers are in.
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/49sdM8w
This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025, and did other readers agree?
🔗 ja.ma/49sdM8w
#Semaglutide consistently lowered hospitalization rates and hospital days in high-risk adults with #obesity and cardiovascular disease, with effects observed across clinical subgroups. ja.ma/3LdVyhO
December 23, 2025 at 6:00 PM
#Semaglutide consistently lowered hospitalization rates and hospital days in high-risk adults with #obesity and cardiovascular disease, with effects observed across clinical subgroups. ja.ma/3LdVyhO
Polygenic scores for hypertrophic and dilated cardiomyopathies independently and oppositely modified disease risk and penetrance of pathogenic variants, supporting bidirectional genetic influences on #Cardiomyopathy. ja.ma/4jam5Jx
December 23, 2025 at 5:00 PM
Polygenic scores for hypertrophic and dilated cardiomyopathies independently and oppositely modified disease risk and penetrance of pathogenic variants, supporting bidirectional genetic influences on #Cardiomyopathy. ja.ma/4jam5Jx
The numbers are in.
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/48TWLUw
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/48TWLUw
December 23, 2025 at 4:30 PM
The numbers are in.
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/48TWLUw
The numbers are in. This year's most popular JAMA Network content spans a range of topics, from #fluoride to #Parkinson disease to #GLP-1s. What was your favorite article in 2025 -- and did other readers agree?
🔗 ja.ma/48TWLUw
Small-interfering RNA olpasiran reduced lipoprotein(a)–apolipoprotein B particles by >95% with minimal rise in non–Lp(a)-apoB, lowering total apoB concentration in patients with cardiovascular disease. ja.ma/493ioQZ
December 22, 2025 at 12:00 PM
Small-interfering RNA olpasiran reduced lipoprotein(a)–apolipoprotein B particles by >95% with minimal rise in non–Lp(a)-apoB, lowering total apoB concentration in patients with cardiovascular disease. ja.ma/493ioQZ
Newborn screening using LDL-C and apolipoprotein B, followed by genetic testing, may substantially improve early diagnosis of familial hypercholesterolemia, a treatable genetic condition. ja.ma/4s4AnPO
December 21, 2025 at 12:00 PM
Newborn screening using LDL-C and apolipoprotein B, followed by genetic testing, may substantially improve early diagnosis of familial hypercholesterolemia, a treatable genetic condition. ja.ma/4s4AnPO
In this subanalysis of the ARTESiA RCT, apixaban increased the risk of major gastrointestinal bleeding compared to aspirin in patients with subclinical atrial fibrillation (SCAF), but fatal and intracranial bleeding rates were similar. ja.ma/4jaQtn1
December 20, 2025 at 12:00 PM
In this subanalysis of the ARTESiA RCT, apixaban increased the risk of major gastrointestinal bleeding compared to aspirin in patients with subclinical atrial fibrillation (SCAF), but fatal and intracranial bleeding rates were similar. ja.ma/4jaQtn1
Among patients with #AtrialFibrillation, elevated BMI, and 1 or more additional cardiometabolic risk factors, aggressive risk factor management reduced arrhythmia recurrence over the 12-month period after catheter ablation. ja.ma/4p7sZR8
December 19, 2025 at 12:00 PM
Among patients with #AtrialFibrillation, elevated BMI, and 1 or more additional cardiometabolic risk factors, aggressive risk factor management reduced arrhythmia recurrence over the 12-month period after catheter ablation. ja.ma/4p7sZR8
Changing from high-sensitivity cardiac troponin I to T assay doubled myocardial injury detection and admissions, without improving 1-year cardiovascular outcomes in suspected #AcuteCoronarySyndrome. ja.ma/4s2tr5J
December 18, 2025 at 2:00 PM
Changing from high-sensitivity cardiac troponin I to T assay doubled myocardial injury detection and admissions, without improving 1-year cardiovascular outcomes in suspected #AcuteCoronarySyndrome. ja.ma/4s2tr5J
Women with preeclampsia, other hypertensive disorders, large for gestational age, preterm delivery, or gestational diabetes were linked to increased long-term risk of atrial fibrillation.
ja.ma/4s59smT
ja.ma/4s59smT
December 18, 2025 at 12:00 PM
Women with preeclampsia, other hypertensive disorders, large for gestational age, preterm delivery, or gestational diabetes were linked to increased long-term risk of atrial fibrillation.
ja.ma/4s59smT
ja.ma/4s59smT
This narrative review describes current guidelines for intervention in severe primary #MitralRegurgitation and explores an approach that incorporates additional injury assessment, novel imaging markers, and biomarkers to optimize surgical timing.
ja.ma/3ME5DVI
ja.ma/3ME5DVI
December 17, 2025 at 5:00 PM
This narrative review describes current guidelines for intervention in severe primary #MitralRegurgitation and explores an approach that incorporates additional injury assessment, novel imaging markers, and biomarkers to optimize surgical timing.
ja.ma/3ME5DVI
ja.ma/3ME5DVI
Intensive lipid-lowering therapy and lower on-treatment LDL-C were associated with less neoatherosclerosis and reduced late stent failure risk after #PCI for STEMI.
ja.ma/4qbqONb
ja.ma/4qbqONb
December 17, 2025 at 4:30 PM
Intensive lipid-lowering therapy and lower on-treatment LDL-C were associated with less neoatherosclerosis and reduced late stent failure risk after #PCI for STEMI.
ja.ma/4qbqONb
ja.ma/4qbqONb
Editorial: Nonoptimal temperatures—both extreme heat and cold—pose major risks for cardiovascular events and mortality worldwide, with climate change intensifying temperature extremes and their health impacts. ja.ma/4s0soDi
December 16, 2025 at 1:00 PM
Editorial: Nonoptimal temperatures—both extreme heat and cold—pose major risks for cardiovascular events and mortality worldwide, with climate change intensifying temperature extremes and their health impacts. ja.ma/4s0soDi
Short-term exposure to both low and high temperatures was associated with increased all-cause and CVD mortality risk among patients with heart failure in Sweden. ja.ma/4pPSesf
December 16, 2025 at 12:05 PM
Short-term exposure to both low and high temperatures was associated with increased all-cause and CVD mortality risk among patients with heart failure in Sweden. ja.ma/4pPSesf
Papillary muscle scarring detected by dark blood MRI in dilated cardiomyopathy patients was independently associated with increased cardiac death, heart failure events, and arrhythmia, offering additional prognostic value. ja.ma/48P3GNp
December 15, 2025 at 12:00 PM
Papillary muscle scarring detected by dark blood MRI in dilated cardiomyopathy patients was independently associated with increased cardiac death, heart failure events, and arrhythmia, offering additional prognostic value. ja.ma/48P3GNp
💬 Editorial: New analysis from the ASPREE trial suggests clonal hematopoiesis of indeterminate potential (CHIP) is linked to increased bleeding risk but not major cardiovascular events in healthy older adults.
ja.ma/4rUxRLP
ja.ma/4rUxRLP
December 14, 2025 at 1:00 PM
💬 Editorial: New analysis from the ASPREE trial suggests clonal hematopoiesis of indeterminate potential (CHIP) is linked to increased bleeding risk but not major cardiovascular events in healthy older adults.
ja.ma/4rUxRLP
ja.ma/4rUxRLP
In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically significant bleeding, and aspirin’s effects on CVD and bleeding did not differ based on CHIP presence. ja.ma/48M35fr
December 14, 2025 at 12:00 PM
In older adults, CHIP was not linked to higher cardiovascular risk but was associated with increased clinically significant bleeding, and aspirin’s effects on CVD and bleeding did not differ based on CHIP presence. ja.ma/48M35fr
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/499NKGQ
December 13, 2025 at 4:00 PM
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/499NKGQ
RCT: Intracardiac echocardiography is non-inferior to transesophageal echocardiography for thromboembolic prevention in atrial fibrillation ablation, with added benefits in safety, efficiency, and patient comfort. ja.ma/4iV1Xe3
December 13, 2025 at 12:00 PM
RCT: Intracardiac echocardiography is non-inferior to transesophageal echocardiography for thromboembolic prevention in atrial fibrillation ablation, with added benefits in safety, efficiency, and patient comfort. ja.ma/4iV1Xe3
📢 This Special Communication describes the ZEUS trial, which will determine whether interleukin-6 inhibition with ziltivekimab reduces heart and kidney events in patients with atherosclerotic disease, chronic kidney disease, and systemic inflammation.
ja.ma/3MEZJDz
ja.ma/3MEZJDz
December 12, 2025 at 3:00 PM
📢 This Special Communication describes the ZEUS trial, which will determine whether interleukin-6 inhibition with ziltivekimab reduces heart and kidney events in patients with atherosclerotic disease, chronic kidney disease, and systemic inflammation.
ja.ma/3MEZJDz
ja.ma/3MEZJDz
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/48xaYXp
December 11, 2025 at 3:00 PM
In 152 male marathon runners, right ventricular ejection fraction declined transiently after a marathon but recovered within 3 days and remained stable at 10-year follow-up. ja.ma/48xaYXp
Integrating common, rare, and somatic genetic variants with clinical factors improves risk prediction for incident atrial fibrillation, aiding screening and prevention efforts. ja.ma/48MIA26
December 11, 2025 at 12:00 PM
Integrating common, rare, and somatic genetic variants with clinical factors improves risk prediction for incident atrial fibrillation, aiding screening and prevention efforts. ja.ma/48MIA26
🎧 Listen to Alfred E. Buxton, MD, and @MarieF_Poulin, MD, discuss their article "Mechanisms Underlying Alterations in Cardiac Conduction After Transcatheter Aortic Valve Replacement: Cardiac Conduction After TAVRt," with @rhythmkris, MD. ja.ma/4iK0rLI
December 10, 2025 at 5:30 PM
🎧 Listen to Alfred E. Buxton, MD, and @MarieF_Poulin, MD, discuss their article "Mechanisms Underlying Alterations in Cardiac Conduction After Transcatheter Aortic Valve Replacement: Cardiac Conduction After TAVRt," with @rhythmkris, MD. ja.ma/4iK0rLI
💬 Editors Note: Many post-TAVR conduction abnormalities resolve quickly and do not predict delayed heart block, suggesting routine permanent pacemaker implantation is often unnecessary.
ja.ma/4iK69xg
ja.ma/4iK69xg
December 10, 2025 at 5:00 PM
💬 Editors Note: Many post-TAVR conduction abnormalities resolve quickly and do not predict delayed heart block, suggesting routine permanent pacemaker implantation is often unnecessary.
ja.ma/4iK69xg
ja.ma/4iK69xg
Among 409 patients undergoing transcatheter aortic valve replacement, intraprocedural block occurred in the atrioventricular node or His bundle, with site-specific predictors for intraprocedural and delayed heart block.
ja.ma/3XLycmj
ja.ma/3XLycmj
December 10, 2025 at 4:30 PM
Among 409 patients undergoing transcatheter aortic valve replacement, intraprocedural block occurred in the atrioventricular node or His bundle, with site-specific predictors for intraprocedural and delayed heart block.
ja.ma/3XLycmj
ja.ma/3XLycmj