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JAMA Cardiology
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JAMA Cardiology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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In the WHO African Region, older age, female sex, lower levels of education, and heavy alcohol consumption were linked to a decreased likelihood of achieving ideal or intermediate cardiovascular health. ja.ma/3LXmv9t
November 24, 2025 at 12:00 PM
Editorial: Microaxial flow pump therapy may be most beneficial for myocardial infarction patients with cardiogenic shock experiencing severe hypotension despite vasopressor use. ja.ma/487BtB1
November 21, 2025 at 1:00 PM
This post hoc analysis of the DanGer Shock RCT suggests that microaxial flow pump treatment may improve survival in patients with STEMI-related cardiogenic shock and profound systolic hypotension. ja.ma/4rdCDUn
November 21, 2025 at 12:00 PM
Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. ja.ma/3KcEvfu
November 20, 2025 at 1:00 PM
Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. ja.ma/48mee7I
November 20, 2025 at 12:00 PM
Editor's Note: Herraiz-Adillo et al report that stage 2 hypertension and even modestly increased systolic blood pressure in young adulthood are independently associated with severe coronary stenosis in midlife. ja.ma/4pgDK3V
November 19, 2025 at 5:00 PM
In this population-based cohort study, higher BP levels in adolescence were associated with a dose-dependent higher risk for atherosclerosis in middle age, particularly for severe coronary atherosclerosis. ja.ma/4oZ8cja
November 19, 2025 at 4:30 PM
In older patients with myocardial infarction and multivessel disease, physiology-guided complete revascularization achieved a sustained reduction in adverse outcomes compared to culprit-only treatment over a 3-year follow-up period. ja.ma/43yOORC
November 18, 2025 at 12:00 PM
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing. ja.ma/485r8WB
November 17, 2025 at 12:00 PM
A previously healthy 55-year-old man presented to his local family medicine clinic after waking up with a buzzing sensation in his chest. What would you do next?

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November 15, 2025 at 12:00 PM
In a national US analysis of TAVR procedures from 2012 to 2024, annual volumes of redo TAVR and TAVR explant increased, TAVR reintervention beyond 5 years is predominantly performed via redo TAVR.

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November 14, 2025 at 12:00 PM
An AI-ECG risk model demonstrated superior prediction of incident complete heart block within 1 year compared to traditional markers. ja.ma/4nSUb5p
November 13, 2025 at 2:00 PM
In a binational study of older adults with diabetes, nearly 60% in the US and 31% in Japan discontinued #GLP-1RAs within 12 months of starting injectable #semaglutide.

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November 13, 2025 at 12:00 PM
In patients with myotonic dystrophy type 1, electrophysiological measurement of the His-ventricular interval is more sensitive and accurate than ECG criteria for identifying those at risk for major bradyarrhythmic events and in need of prophylactic pacing.

ja.ma/4nI0QzJ
November 12, 2025 at 5:30 PM
💬 Editorial: Guideline-directed medical therapy and structured plaque assessment may advance prevention for patients with nonobstructive, high-risk carotid plaques.

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November 12, 2025 at 4:45 PM
In this subanalysis of the ARTESiA RCT, apixaban increased the risk of major gastrointestinal bleeding compared to aspirin in patients with subclinical atrial fibrillation (SCAF), but fatal and intracranial bleeding rates were similar.

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November 12, 2025 at 4:30 PM
Non-DNMT3A clonal hematopoiesis of indeterminate potential (CHIP) subtypes—including TET2, ASXL1, JAK2, and spliceosome genes—demonstrated higher association with incident heart failure compared to DNMT3A.

ja.ma/4qK5nnw
November 11, 2025 at 2:00 PM
Moderate to vigorous physical activity in guideline-recommended ranges was associated with lower risk of adverse cardiovascular outcomes and did not increase arrhythmia risk or pathologic cardiac remodeling in G+P− carriers.

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November 11, 2025 at 1:00 PM
Pretreatment with atorvastatin during anthracycline chemotherapy was associated with preserved aortic vascular function in lymphoma patients, lowering odds of increased stiffness vs placebo.

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November 11, 2025 at 12:00 PM
Acoramidis demonstrated equivalent benefit for mortality and cardiovascular hospitalization in wild-type and variant ATTR-CM, including p.Val142Ile, over 42 months of follow-up.

ja.ma/3JTSjLO
November 11, 2025 at 11:00 AM
From @jamanetworkopen.com: Among adults with symptoms after #COVID19 infection, a pragmatic, home-based resistance exercise program is a generalizable, safe, and effective therapy for improving physical and psychological function.

#AHA25 @ahascience.bsky.social

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November 10, 2025 at 8:29 PM
From @jamanetworkopen.com: For home health aides (HHAs) caring for adults with #HeartFailure (HF), HF training improved HHA knowledge and self-efficacy, with greatest gains among those with the lowest baseline scores.

#AHA25 @ahascience.bsky.social

ja.ma/47zLpoa
November 10, 2025 at 8:09 PM
Editor’s Note: Prospective pilot data by Jain et al validate an #AI model for ATTR-CM screening; real-world implementation challenges and outcome effects require further study.

#AHA25 @ahascience.bsky.social

ja.ma/4oxBPrT
November 10, 2025 at 8:05 PM
#AI model ATTRACTnet improved detection of undiagnosed ATTR-CM, with a >2.8-fold higher diagnostic yield vs historical controls and increased system-wide case identification.

#AHA25 @ahascience.bsky.social

ja.ma/3WLzv4g
November 10, 2025 at 8:00 PM
Robert Bonow, MD, MS, is celebrated at #AHA25. Dr Bonow, founding editor of JAMA Cardiology, marked 10 years as its Editor in Chief.
November 9, 2025 at 11:02 PM