Swapnil Hiremath 🍁🇨🇦
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hswapnil.medsky.social
Swapnil Hiremath 🍁🇨🇦
@hswapnil.medsky.social
Nephrologist = kidney doctor
MD, MPH
Professor, University of Ottawa/Ottawa Hospital 🇨🇦
He/Him/His
#NephJC co-creator, @FreelyFiltered.bsky.social pod panelist
#NephSky
https://www.swapnilhiremath.com
Pinned
Update

Link changed (will not change again)

So if you liked/pinned the old feed, please do it again!

bsky.app/profile/did:...

#NephSky
If you are a nephrology or kidney disease or renal professional or interested in the field - make sure you have liked/followed/pinned the nephrology feed

bsky.app/profile/did:...

Thanks again to @richardferro.xyz for creating & updating this! It’s a one-stop shop for nephrology needs

#NephSky
Reposted by Swapnil Hiremath 🍁🇨🇦
Great piece on the FDA and menopause hormone therapy in @motherjones.com it is the most medically accurate coverage I have read from the press! www.motherjones.com/politics/202...
The many problems with the FDA’s big menopause announcement
No, it doesn't kill women or cause divorce.
www.motherjones.com
November 11, 2025 at 10:55 AM
Reposted by Swapnil Hiremath 🍁🇨🇦
#KidneyWk 2025 comes to a close in Houston. Thank you for being part of the world's premier nephrology meeting. 📅 Mark your calendars—#KidneyWk 2026 takes place October 21–25 in Denver, Colorado.
November 10, 2025 at 10:19 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
NEW ON #AJKDBlog:

This year AJKD inducted seven remarkable reviewers into the AJKD Reviewer Hall of Fame. The editors thank and congratulate these reviewers, all of whom shared why they participate in the peer review process:

bit.ly/47y3R0o
November 10, 2025 at 11:00 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
As expected, Canada has lost its measles-free status because of the long-running outbreak there. With it goes the #measles elimination status of the entire zone of the Americas, the only division of the #WHO to ever have achieved measles elimination. www.statnews.com/2025/11/10/m...
Canada loses measles elimination status — as does the entire Americas region
Canada has formally lost its measles elimination status, the country’s public health agency announced, triggering the loss of that status throughout all of the Americas.
www.statnews.com
November 10, 2025 at 2:49 PM
It is all a fait accompli by now - built its official - we have lost our measles elimination status

www.canada.ca/en/public-he...
November 10, 2025 at 6:26 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
The editorial of this paper is kind of funny. They don't recommend use given "outsized results of early trials have failed to be replicated". Given the effect size is ginormous, the likelihood that any meta-analysis would not show that this is beneficial is very small.

www.nejm.org/doi/full/10....
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | NEJM
Cardiovascular disease is the leading cause of death in patients receiving hemodialysis, yet effective preventive therapies remain limited. Supplementation with n−3 polyunsaturated fatty acids, esp...
www.nejm.org
November 10, 2025 at 2:27 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
Incretins are the G-force : Guardians of (Inner) Space(*).
No more glipination @hswapnil.medsky.social @mikejohansenmd.medsky.social @rnflex.bsky.social,only G force

(*)a reference to the 1980s US adaptation of the 1972 Japanese anime Gatchaman but feel free to substitute the 2009 guinea pig movie
November 10, 2025 at 2:44 PM
AI in Healthcare

@asakhuja.bsky.social gave an excellent overview of what this entails, the opportunities and its limitations

youtu.be/0qOaoGncKHw?...

#NephGR #NephSky
AI in Healthcare with Dr Ankit Sakhuja
YouTube video by Ottawa Nephrology
youtu.be
November 10, 2025 at 12:03 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
Salt-Induced Vascular Damage in Hypertension Involves Redox Activation of PARP/TRPM2 Signaling and Inflammasome Assembly

🔗 academic.oup.com/ajh/article/... 🔓

#EditorsChoice #Free
Salt-Induced Vascular Damage in Hypertension Involves Redox Activation of PARP/TRPM2 Signaling and Inflammasome Assembly
AbstractBACKGROUND. Excess sodium intake induces vascular dysfunction. Molecular mechanisms underlying this are unclear. Here we investigated the role of r
academic.oup.com
November 10, 2025 at 11:45 AM
Pasta 🍝 tariffs?

In the @wsj.com apple.news/AGRDGheVXS_G...

And private equity (which own the US pasta makers) in involved
November 10, 2025 at 11:05 AM
Reposted by Swapnil Hiremath 🍁🇨🇦
I had a lovely catch up chat with @jamesheathers.bsky.social at the weekend. I am thoroughly inspired by the work he and team are doing at the Medical Evidence Project. They act on tip offs for fraudulent and/or inaccurate science used to shape medical practice. Know any? medicalevidenceproject.org
The Medical Evidence Project
We find bad research that affects health and life
medicalevidenceproject.org
November 10, 2025 at 8:30 AM
OK thread of all simulpubs at this year's #KidneyWk

ORIGIN-3: Atacicept pubmed.ncbi.nlm.nih.gov/41196369/

CKD as a curable dz? www.kidney-international.org/article/S008...

Albuminuria as a surrogate endpoint www.nature.com/articles/s41...
November 9, 2025 at 11:30 PM
Congrats @spjuraschek.bsky.social and team for the successful completion of the GOFRESH trial!

#Hypertension #AHA25
RCT: Home-delivered, low-sodium Dietary Approaches to Stop Hypertension (DASH) groceries and dietitian support temporarily improved blood pressure and LDL cholesterol in Black adults with high BP versus monetary support.

#AHA25 @ahascience.bsky.social

ja.ma/4oZ5JVI
November 9, 2025 at 10:32 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
RCT: Home-delivered, low-sodium Dietary Approaches to Stop Hypertension (DASH) groceries and dietitian support temporarily improved blood pressure and LDL cholesterol in Black adults with high BP versus monetary support.

#AHA25 @ahascience.bsky.social

ja.ma/4oZ5JVI
November 9, 2025 at 10:25 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
Scholars - if you're publishing articles behind a paywall, why not make your work accessible to everyone by also publishing a preprint version?
November 9, 2025 at 10:14 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
It's weird b/c undifferentiated fish oil doesn't do much but cause Afib in the general population (eicosapent ethyl works though)
November 9, 2025 at 8:39 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease

🔗 academic.oup.com/ajh/article/... 🔓

#WeekendRead from the #EditorsChoice
Association of Arterial Stiffness With Kidney Function Among Adults Without Chronic Kidney Disease
AbstractBACKGROUND. Our aims were to assess whether arterial stiffness is associated with a higher risk for kidney dysfunction among persons without chroni
academic.oup.com
November 9, 2025 at 1:45 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
For those with a scholarly interest in Franklin, Watson, and other pioneering researchers in molecular biology, @sciencehistory.org has just opened our new landmark collection of their papers, and applications for research fellowships are currently open:

www.sciencehistory.org/hmbc
History of Molecular Biology Collection
This unparalleled collection includes Rosalind Franklin's historic 'Photo 51,' which revealed the double-helix structure of DNA.
www.sciencehistory.org
November 8, 2025 at 3:39 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
9/ "So, there we were. A group of Black Americans confronted with all these dead white Americans… When they were alive, we couldn’t sit in the same room."
November 9, 2025 at 9:23 AM
Reposted by Swapnil Hiremath 🍁🇨🇦
Turns out the effect size it similar in other trials that are probably just underpowered
journals.lww.com/cjasn/abstra...

jamanetwork.com/journals/jam...

#NephSky
journals.lww.com
November 9, 2025 at 12:05 PM
Reposted by Swapnil Hiremath 🍁🇨🇦
I think everyone is rightly sceptical if the large effect size, but given the high risk CVD risk and low cost/risk with fish oil, I feel it is too reactionary to just say “we need more trials”. We always need more trials, but they’re not likely to be forthcoming any time soon.
#NephSky
November 9, 2025 at 12:00 PM
If you read only one obit of James Watson, read this one

www.statnews.com/2025/11/07/j...

(From the late Sharon Begley, for @statnews.com )
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 9, 2025 at 11:56 AM
Summary from the #NephJC team of day 3

www.nephjc.com/news/2025/11...

Since we had only two trials simul-published today at #KidneyWk we took some creative license on what to include !

@nephroseeker.medsky.social with the beautiful graphics and tables apart from the lion’s share of writing!
Kidney Week in Houston: Day 3 — NephJC
Day 3 of Kidney Week. Sibeprenlimab and Balcinrenone on NEJM and Lancet, plus a couple of other non-kidneywk studies,
www.nephjc.com
November 9, 2025 at 4:28 AM