🔥 Discover this awesome post from Hacker News 📖 📂 Category: 📌 Main takeaway: Serious injury to short-term kidney function, known as acute kidney injury (AKI), can be life-threatening and also raise the likelihood of developing permanent chronic kidney disease. AKI can occur after major stressors such as sepsis or heart surgery, and more than half of all intensive care patients experience it.

Hepatology International -

Blocking fatty ceramides could stop acute kidney injury—and possibly revolutionize mitochondrial disease treatment.

Nature, Published online: 13 November 2025; doi:10.1038/s41586-025-09847-6Physiology and immunology of pig-to-human decedent kidney xenotransplant

Credit: Pixabay/CC0 Public Domain Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human. More than 800,000 Americans have late-stage kidney disease, yet only 3% receive a transplant each year, according to the U.S. Centers for Disease Control and Prevention. To boost the supply of available organs, experts are exploring the use of genetically modified pig kidneys. The genetic changes are meant to keep the human immune system from recognizing the animal organ as foreign and attacking it to cause rejection.

Chronic kidney disease (CKD) affects 9.1% globally and is associated with significant morbidity and mortality. While up to 10% of CKD cases yield a genetic diagnosis with hundreds of implicated genes ...

Acute kidney injury (AKI) is a common and important complication of major surgery, yet recommended preventive care is rarely administered. We used uri…

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International guidelines do not consider moderate or severe obesity to be contraindications to kidney transplantation, but clinical practice suggests otherwise. This study sought to evaluate the likel...

Vancomycin is the preferred treatment for methicillin-resistant Staphylococcus aureus (MRSA) infections but is known for its nephrotoxic effect. It is often administered empirically before culture res...