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JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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Calling all early-career researchers! Applications for the JAMA Network Open Editorial Fellowship will close this Sunday, February 15.

Fellows will experience the publishing process firsthand, team up with experienced editors, & coauthor commentary.

🔗Apply here: ja.ma/3Z6cRVa
February 11, 2026 at 12:00 PM
Blood total tau, phosphorylated tau, and brain-derived tau were elevated after multiple traumatic injuries, correlating with injury severity and outcome, with sustained BD-tau elevation in the acute phase. bit.ly/3ZtmZYC
February 10, 2026 at 7:30 PM
Post-COVID-19, #iGAS incidence was over 70 times higher among persons experiencing homelessness in Toronto than among housed adults, with distinct risk profiles and strains. bit.ly/4tAGOLp
February 10, 2026 at 6:30 PM
Nonsurgical management and bilateral mastectomy for low-risk, hormone receptor–positive #DCIS both increased from 2004 to 2022; endocrine therapy peaked in 2020 then declined, with persistent sociodemographic variation. bit.ly/3O06NeZ
February 10, 2026 at 6:15 PM
Combined #GLP-1 receptor agonist and progestin therapy for benign uterine disease or hyperplasia was associated with lower #EndometrialCancer risk and reduced hysterectomy rates compared to progestin alone. bit.ly/4ksq5Wr
February 10, 2026 at 6:00 PM
A learning health systems intervention for justice-involved youth improved timeliness of #SubstanceUseDisorder risk screening, treatment initiation, and engagement across two service systems. bit.ly/4rzL23O
February 10, 2026 at 5:45 PM
Participation in a multicenter #EmergencyMedicine #OUD clinical trial was associated with greater clinician training, expanded research, improved care, and increased professional opportunities at engaged sites.

bit.ly/4tqgsLL
February 9, 2026 at 6:45 PM
Among RNs who left hospital roles, adequate staffing, flexible scheduling, and higher wages or benefits were cited as key factors that would increase the likelihood of returning to hospital #Nursing roles.

bit.ly/4rEn07Q
February 9, 2026 at 6:30 PM
Wastewater analysis in Australia indicated overall declines in #Tobacco use but documented increases in nicotine from #Vaping and expansion of the illicit tobacco market between 2017 and 2023.

bit.ly/3ZZcso4
February 9, 2026 at 6:15 PM
Higher stage at diagnosis was linked to lower 3-year survival for childhood solid tumors, with regional survival differences sometimes explained by stage and sometimes by other factors in the #BENCHISTA study.

bit.ly/4bFH3OE
February 9, 2026 at 6:00 PM
Systematic review and meta-analysis: Routine predischarge car seat tolerance screening was not associated with reduced 30-day mortality or readmission in preterm or at-risk full-term infants; approximately 1 in 9 failed initial screening.

bit.ly/4bPSO5j
February 9, 2026 at 5:45 PM
Receipt of early intervention (#EI) services before age 3 in children with moderate to severe developmental delays was linked with improved third-grade math and English language arts achievement.

bit.ly/4tpBkCX
February 9, 2026 at 5:15 PM
Outpatient #Telemedicine visits were associated with lower 30-day episode charges and fewer subsequent visits than in-person care, with comparable charges for mental and behavioral health conditions.

bit.ly/4tG2Zjk
February 9, 2026 at 5:15 PM
RCT: Internet-based cognitive resilience training reduced the risk of #PTSD or major depressive disorder at 1-year follow-up among early career paramedics compared to psychoeducation or standard practice.

bit.ly/3MnahHH
February 9, 2026 at 5:00 PM
Analysis of US commercial health plans found that higher net prices, but not rebates, were associated with more frequent coverage restrictions for specialty drugs; rebates did not decrease the likelihood of access restrictions.

bit.ly/3ZQKw5M
February 7, 2026 at 3:30 PM
Survey data indicate that 68% of US adults support “Baby Bonds”—public investment accounts for children born into low-income households—with bipartisan support and greater favorability among those with fewer assets.

jamanetwork.com/journals/jam...
February 7, 2026 at 3:00 PM
Among older adults recovering from #TBI, most reported good outcomes on standard measures, but interviews revealed critical effects of caregiver support, emotional adaptation, and unmet needs for post-injury guidance.

bit.ly/45Q3NYx
February 7, 2026 at 2:30 PM
About 20% of US women eligible for cervical #cancer screening preferred home-based self-sampling, while 61% preferred clinic-based testing; preference for self-sampling was higher among those who had experienced prejudice/discrimination in medical care.

bit.ly/3ZiajDP
February 7, 2026 at 2:00 PM
Safety of advanced therapies for #CrohnDisease—tumor necrosis factor antagonists, anti-integrins, interleukin inhibitors, and Janus kinase inhibitors—was comparable, with no significant differences in serious infection, VT, or cardiovascular event risk.

bit.ly/4rzRyaQ
February 7, 2026 at 1:30 PM
Combining 5-minute Apgar scores with umbilical artery pH improved risk estimation for mortality and severe intraventricular hemorrhage in very preterm infants, supporting joint use for more precise outcome assessment.

bit.ly/3MbdABS
February 7, 2026 at 1:00 PM
In this nonrandomized clinical trial, the MUTTON-HF intervention incorporating Indigenous recipes and locally sourced Native food was feasible and acceptable for patients with heart failure in rural Navajo Nation.

jamanetwork.com/journals/jam...
February 7, 2026 at 12:30 PM
RCT: Peer navigator intervention after nonfatal opioid overdose did not significantly reduce #opioid-related adverse events at 12 months vs standard care in emergency department patients in New York City.

bit.ly/4tlitch
February 7, 2026 at 12:00 PM
A nationwide autopsy study in Japan found latent #Cancer prevalence to be several-fold higher than clinical diagnoses, with metastatic latent cancers rising over time, demonstrating the continuing importance of autopsy for cancer epidemiology.

bit.ly/4tik0zK
February 6, 2026 at 3:00 PM
Infants in vegan households had similar growth patterns to omnivorous peers but higher odds of underweight in early infancy, with differences diminishing by 24 months and no significant effects on stunting or overweight.

bit.ly/46jLriM
February 6, 2026 at 2:30 PM
In patients with #Cancer, greater financial toxicity was associated with lower satisfaction with life, a relationship partially explained by less hopefulness and reduced perceived social support.

jamanetwork.com/journals/jam...
February 6, 2026 at 2:00 PM