JAMA Network Open
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JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
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RCT: Among adults with lingering symptoms after #COVID19 infection, a pragmatic, home-based resistance exercise program is a generalizable, safe, and effective therapy for improving both physical and psychological function.
#AHA25 @ahascience.bsky.social
ja.ma/4oxRasr
#AHA25 @ahascience.bsky.social
ja.ma/4oxRasr
November 10, 2025 at 8:25 PM
RCT: Among adults with lingering symptoms after #COVID19 infection, a pragmatic, home-based resistance exercise program is a generalizable, safe, and effective therapy for improving both physical and psychological function.
#AHA25 @ahascience.bsky.social
ja.ma/4oxRasr
#AHA25 @ahascience.bsky.social
ja.ma/4oxRasr
Pilot RCT: For home health aides (HHAs) caring for adults with #HeartFailure (HF), HF training improved HHA knowledge and self-efficacy, with greatest gains among those with the lowest baseline scores.
#AHA25 @ahascience.bsky.social
ja.ma/4qRI6Qx
#AHA25 @ahascience.bsky.social
ja.ma/4qRI6Qx
November 10, 2025 at 7:45 PM
Pilot RCT: For home health aides (HHAs) caring for adults with #HeartFailure (HF), HF training improved HHA knowledge and self-efficacy, with greatest gains among those with the lowest baseline scores.
#AHA25 @ahascience.bsky.social
ja.ma/4qRI6Qx
#AHA25 @ahascience.bsky.social
ja.ma/4qRI6Qx
In a cohort of over 107,000 first-year US residents, 37% reported advanced or native proficiency in a non-English language, but major language gaps remain compared to population need for language-concordant care. ja.ma/49IGzWS
November 10, 2025 at 6:00 PM
In a cohort of over 107,000 first-year US residents, 37% reported advanced or native proficiency in a non-English language, but major language gaps remain compared to population need for language-concordant care. ja.ma/49IGzWS
In this cohort study of women with gestational #diabetes (GD), elevated fasting glucose levels during the diagnostic test for GD conferred higher prevalence of prediabetes at 6-9 weeks than isolated post-load intolerance. ja.ma/47TnhMd
November 10, 2025 at 5:45 PM
In this cohort study of women with gestational #diabetes (GD), elevated fasting glucose levels during the diagnostic test for GD conferred higher prevalence of prediabetes at 6-9 weeks than isolated post-load intolerance. ja.ma/47TnhMd
In this Nordic cohort study of offspring, paternal exposure to valproate in the three months before conception was associated with a higher risk of neurodevelopmental disorders, compared with lamotrigine or levetiracetam exposure. ja.ma/3LqzX5t
November 10, 2025 at 5:32 PM
In this Nordic cohort study of offspring, paternal exposure to valproate in the three months before conception was associated with a higher risk of neurodevelopmental disorders, compared with lamotrigine or levetiracetam exposure. ja.ma/3LqzX5t
Among pregnant women, 79% of homicides involved a firearm, and state-level firearm ownership estimates remained associated with homicide rates even after adjusting for sociodemographic factors. ja.ma/3WJSUma
November 10, 2025 at 5:15 PM
Among pregnant women, 79% of homicides involved a firearm, and state-level firearm ownership estimates remained associated with homicide rates even after adjusting for sociodemographic factors. ja.ma/3WJSUma
RCT: Among older adults, combining a patient-reported outcome with a passive digital marker increased new #dementia diagnoses by 31% in primary care clinics compared with usual care. ja.ma/47yYvSz
November 10, 2025 at 5:07 PM
RCT: Among older adults, combining a patient-reported outcome with a passive digital marker increased new #dementia diagnoses by 31% in primary care clinics compared with usual care. ja.ma/47yYvSz
In this cohort study of #ColorectalCancer survivors, 47% reported bowel-related symptoms at 6 months and 36% at 5 years after diagnosis, with higher dietary fiber intake linked to a lower prevalence of diarrhea. ja.ma/4oUuUIQ
November 10, 2025 at 5:02 PM
In this cohort study of #ColorectalCancer survivors, 47% reported bowel-related symptoms at 6 months and 36% at 5 years after diagnosis, with higher dietary fiber intake linked to a lower prevalence of diarrhea. ja.ma/4oUuUIQ
RCT: Among people released from pretrial jail detention, those who received the Safety Planning Intervention with telephone follow-up experienced 42% fewer suicide events over 12 months compared with enhanced standard care. ja.ma/4oWA6vW
November 10, 2025 at 5:01 PM
RCT: Among people released from pretrial jail detention, those who received the Safety Planning Intervention with telephone follow-up experienced 42% fewer suicide events over 12 months compared with enhanced standard care. ja.ma/4oWA6vW
A comprehensive electronic patient-reported outcome system with self-management coaching and nurse practitioner follow-up was the most cost-effective strategy for reducing symptom burden during chemotherapy. ja.ma/4oyEPnZ
November 10, 2025 at 5:00 PM
A comprehensive electronic patient-reported outcome system with self-management coaching and nurse practitioner follow-up was the most cost-effective strategy for reducing symptom burden during chemotherapy. ja.ma/4oyEPnZ
For neonates with congenital heart defects (CHDs) in Illinois, delayed #prenatal care initiation was associated with a higher probability of delivery at a pediatric #cardiac center, especially for severe CHD.
#AHA25 @ahascience.bsky.social
ja.ma/3JD7NDS
#AHA25 @ahascience.bsky.social
ja.ma/3JD7NDS
November 9, 2025 at 6:45 PM
For neonates with congenital heart defects (CHDs) in Illinois, delayed #prenatal care initiation was associated with a higher probability of delivery at a pediatric #cardiac center, especially for severe CHD.
#AHA25 @ahascience.bsky.social
ja.ma/3JD7NDS
#AHA25 @ahascience.bsky.social
ja.ma/3JD7NDS
Meta-analysis: Compared to standard regimens, trastuzumab emtansine exhibited a more favorable cardiotoxicity profile, while other novel and standard therapies demonstrated comparable risks of LVEF decline.
#AHA25 @ahascience.bsky.social
ja.ma/3XfYIE3
#AHA25 @ahascience.bsky.social
ja.ma/3XfYIE3
November 9, 2025 at 5:45 PM
Meta-analysis: Compared to standard regimens, trastuzumab emtansine exhibited a more favorable cardiotoxicity profile, while other novel and standard therapies demonstrated comparable risks of LVEF decline.
#AHA25 @ahascience.bsky.social
ja.ma/3XfYIE3
#AHA25 @ahascience.bsky.social
ja.ma/3XfYIE3
Participant interviews from the Navigate-Kidney trial show that community health workers helped Latino patients manage complex health and social challenges tied to #dialysis care.
#KidneyWk @asnkidney.bsky.social
ja.ma/47so6wo
#KidneyWk @asnkidney.bsky.social
ja.ma/47so6wo
November 7, 2025 at 11:55 PM
Participant interviews from the Navigate-Kidney trial show that community health workers helped Latino patients manage complex health and social challenges tied to #dialysis care.
#KidneyWk @asnkidney.bsky.social
ja.ma/47so6wo
#KidneyWk @asnkidney.bsky.social
ja.ma/47so6wo
Of 950 FDA-cleared AI/ML-enabled medical devices since 1995, 76% were for radiology, with few undergoing prospective or clinical testing, and only 8% including a human-in-the-loop component. ja.ma/4hLirF4
November 7, 2025 at 5:30 PM
Of 950 FDA-cleared AI/ML-enabled medical devices since 1995, 76% were for radiology, with few undergoing prospective or clinical testing, and only 8% including a human-in-the-loop component. ja.ma/4hLirF4
In this national survey, 13.1% of US adolescents and young adults reported using generative #AI for mental health advice, with rates highest (22.2%) among those aged 18–21 years. ja.ma/3JJHEDd
November 7, 2025 at 5:15 PM
In this national survey, 13.1% of US adolescents and young adults reported using generative #AI for mental health advice, with rates highest (22.2%) among those aged 18–21 years. ja.ma/3JJHEDd
Participants who identified as Asian, held a graduate degree, or were retired had higher odds of meeting American Cancer Society Guideline Scores for diet, physical activity, alcohol, and BMI, compared with other groups. ja.ma/3WMOtaa
November 7, 2025 at 5:00 PM
Participants who identified as Asian, held a graduate degree, or were retired had higher odds of meeting American Cancer Society Guideline Scores for diet, physical activity, alcohol, and BMI, compared with other groups. ja.ma/3WMOtaa
Among women with prior gestational diabetes, higher adherence to the Planetary Health Diet was associated with lower risk of type 2 #diabetes and CV disease, and less weight gain. ja.ma/3LtqDxN
November 7, 2025 at 4:45 PM
Among women with prior gestational diabetes, higher adherence to the Planetary Health Diet was associated with lower risk of type 2 #diabetes and CV disease, and less weight gain. ja.ma/3LtqDxN
In this case series of over 54 million US deaths, both low and high temperatures were associated with increased mortality, with annual deaths from low temperatures estimated at 45,992 and from high temperatures at 3,414. ja.ma/47LujCm
November 7, 2025 at 4:30 PM
In this case series of over 54 million US deaths, both low and high temperatures were associated with increased mortality, with annual deaths from low temperatures estimated at 45,992 and from high temperatures at 3,414. ja.ma/47LujCm
RCT: Low-molecular-weight heparin plus insulin did not reduce the incidence of new-onset organ failure and/or mortality compared to insulin alone in patients with hypertriglyceridemic #pancreatitis. ja.ma/4osG4Vp
November 7, 2025 at 4:15 PM
RCT: Low-molecular-weight heparin plus insulin did not reduce the incidence of new-onset organ failure and/or mortality compared to insulin alone in patients with hypertriglyceridemic #pancreatitis. ja.ma/4osG4Vp
In patients with spontaneous #CervicalArteryDissection, the presence of fibromuscular dysplasia was associated with distinct correlates and a 2.75x higher rate of recurrent dissection. ja.ma/3LnLjqZ
November 6, 2025 at 5:30 PM
In patients with spontaneous #CervicalArteryDissection, the presence of fibromuscular dysplasia was associated with distinct correlates and a 2.75x higher rate of recurrent dissection. ja.ma/3LnLjqZ
In patients treated with molecularly targeted cancer medications, CDK4/6, EGFR, VEGFR & BRAF inhibitors were linked to higher rates of progressive kidney dysfunction vs controls. ja.ma/3WDFiJd
November 6, 2025 at 5:15 PM
In patients treated with molecularly targeted cancer medications, CDK4/6, EGFR, VEGFR & BRAF inhibitors were linked to higher rates of progressive kidney dysfunction vs controls. ja.ma/3WDFiJd
A cross-sectional survey in British Columbia, Canada, found 99% of reproductive-aged females lived within a 15-minute drive of a mifepristone-dispensing pharmacy, though 23% of pharmacies neither dispensed within 3 days nor provided a valid referral. ja.ma/3Li75MS
November 6, 2025 at 5:00 PM
A cross-sectional survey in British Columbia, Canada, found 99% of reproductive-aged females lived within a 15-minute drive of a mifepristone-dispensing pharmacy, though 23% of pharmacies neither dispensed within 3 days nor provided a valid referral. ja.ma/3Li75MS
#MachineLearning models using self-report data predicted response to internet CBT for depression and generalized to antidepressant patients, but showed treatment-specificity only after retraining on patients receiving exclusively a single treatment. ja.ma/47VfPRL
November 6, 2025 at 4:45 PM
#MachineLearning models using self-report data predicted response to internet CBT for depression and generalized to antidepressant patients, but showed treatment-specificity only after retraining on patients receiving exclusively a single treatment. ja.ma/47VfPRL
In high-risk soft-tissue sarcoma, histopathological analysis after neoadjuvant chemotherapy showed that sclerohyalinosis >20% was associated with improved disease-free survival. ja.ma/3XbXj1h
November 6, 2025 at 4:30 PM
In high-risk soft-tissue sarcoma, histopathological analysis after neoadjuvant chemotherapy showed that sclerohyalinosis >20% was associated with improved disease-free survival. ja.ma/3XbXj1h
In this randomized clinical trial of patients with acute peripheral vertigo, combination therapy provided better symptom relief than diphenhydramine alone. ja.ma/4nFmLaa
November 6, 2025 at 4:15 PM
In this randomized clinical trial of patients with acute peripheral vertigo, combination therapy provided better symptom relief than diphenhydramine alone. ja.ma/4nFmLaa