Isaac Bogoch
@isaacbogoch.bsky.social
Infectious Diseases physician and scientist, with thoughts on Infectious Diseases, Tropical Medicine, HIV Prevention, Public Health, Biosecurity, and Global Health issues.
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Isaac Bogoch
@isaacbogoch.bsky.social
· Feb 1
To our American friends who may now be struggling to find health information on US websites: Please check out the Public Health Agency of Canada's website for helpful resources, updated dashboards & practical health tips.
🇨🇦🇨🇦🇨🇦
canada.ca/en/public-he...
🇨🇦🇨🇦🇨🇦
canada.ca/en/public-he...
Regardless of where you land on COVID’s origins, accidental laboratory leaks are a known risk - they can and do happen. Preventing them requires a serious, ongoing global investment in biosafety and biosecurity.
A good read, by Manuel Ansede: tinyurl.com/a27pbr3p
A good read, by Manuel Ansede: tinyurl.com/a27pbr3p
December 30, 2025 at 5:04 PM
Regardless of where you land on COVID’s origins, accidental laboratory leaks are a known risk - they can and do happen. Preventing them requires a serious, ongoing global investment in biosafety and biosecurity.
A good read, by Manuel Ansede: tinyurl.com/a27pbr3p
A good read, by Manuel Ansede: tinyurl.com/a27pbr3p
Merry Christmas and happy holidays.
Thank you to everyone working today, especially those keeping our healthcare system up and running.
Thank you to everyone working today, especially those keeping our healthcare system up and running.
December 25, 2025 at 11:34 AM
Merry Christmas and happy holidays.
Thank you to everyone working today, especially those keeping our healthcare system up and running.
Thank you to everyone working today, especially those keeping our healthcare system up and running.
Chikungunya is a mosquito-borne illness found in many tropical regions that can cause significant discomfort.
A vaccine is available in Canada, but use should limited to specific situations because risks generally outweigh benefits for most people.
Link: tinyurl.com/yr5bufdv
A vaccine is available in Canada, but use should limited to specific situations because risks generally outweigh benefits for most people.
Link: tinyurl.com/yr5bufdv
December 24, 2025 at 5:28 PM
Chikungunya is a mosquito-borne illness found in many tropical regions that can cause significant discomfort.
A vaccine is available in Canada, but use should limited to specific situations because risks generally outweigh benefits for most people.
Link: tinyurl.com/yr5bufdv
A vaccine is available in Canada, but use should limited to specific situations because risks generally outweigh benefits for most people.
Link: tinyurl.com/yr5bufdv
Antibiotic-resistant typhoid infections are a growing global health problem, made worse now by emerging carbapenem resistance.
tinyurl.com/4uy7f6y3 by Thirumoorthy et al.
tinyurl.com/4uy7f6y3 by Thirumoorthy et al.
December 22, 2025 at 2:54 PM
Antibiotic-resistant typhoid infections are a growing global health problem, made worse now by emerging carbapenem resistance.
tinyurl.com/4uy7f6y3 by Thirumoorthy et al.
tinyurl.com/4uy7f6y3 by Thirumoorthy et al.
Canada is in the midst of a rough flu season.
It's not too late to get a flu shot.
It's not too late to get a flu shot.
December 19, 2025 at 9:38 PM
Canada is in the midst of a rough flu season.
It's not too late to get a flu shot.
It's not too late to get a flu shot.
There is a lot of influenza circulating in Canada right now.
The flu can be especially rough on older adults & young kids...see below for current flu hospitalization rates.
It’s not too late to get your flu shot if you haven’t already.
The flu can be especially rough on older adults & young kids...see below for current flu hospitalization rates.
It’s not too late to get your flu shot if you haven’t already.
December 13, 2025 at 8:57 PM
There is a lot of influenza circulating in Canada right now.
The flu can be especially rough on older adults & young kids...see below for current flu hospitalization rates.
It’s not too late to get your flu shot if you haven’t already.
The flu can be especially rough on older adults & young kids...see below for current flu hospitalization rates.
It’s not too late to get your flu shot if you haven’t already.
Reposted by Isaac Bogoch
#FDA has approved a new 1st-in-class oral antibiotic for the treatment of #gonorrhea, which has been making its way through the armamentarium of available antibiotics. Nuzolvence was brought to market through a private-public partnership involving @gardp.bsky.social. www.statnews.com/2025/12/12/f...
FDA approves first new kind of drug to target gonorrhea in decades
The bacterium that causes gonorrhea has developed resistance to nearly every antibiotic used against it
www.statnews.com
December 12, 2025 at 7:23 PM
#FDA has approved a new 1st-in-class oral antibiotic for the treatment of #gonorrhea, which has been making its way through the armamentarium of available antibiotics. Nuzolvence was brought to market through a private-public partnership involving @gardp.bsky.social. www.statnews.com/2025/12/12/f...
Flu season is here, and it might be a tougher one than usual.
It is not too late to get your flu shot.
It is not too late to get your flu shot.
December 6, 2025 at 1:25 PM
Flu season is here, and it might be a tougher one than usual.
It is not too late to get your flu shot.
It is not too late to get your flu shot.
Two cases of Middle Eastern Respiratory Syndrome (MERS), a dangerous viral infection, detected in France in travellers from the Arabian Peninsula.
Another reminder that our world is deeply interconnected & vigilance for imported infections is essential.
tinyurl.com/4mdhwfdz
Another reminder that our world is deeply interconnected & vigilance for imported infections is essential.
tinyurl.com/4mdhwfdz
December 4, 2025 at 4:35 PM
Two cases of Middle Eastern Respiratory Syndrome (MERS), a dangerous viral infection, detected in France in travellers from the Arabian Peninsula.
Another reminder that our world is deeply interconnected & vigilance for imported infections is essential.
tinyurl.com/4mdhwfdz
Another reminder that our world is deeply interconnected & vigilance for imported infections is essential.
tinyurl.com/4mdhwfdz
On World AIDS Day, remember that HIV risk often changes over time & that our prevention tools keep expanding.
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
December 1, 2025 at 5:22 PM
On World AIDS Day, remember that HIV risk often changes over time & that our prevention tools keep expanding.
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
PrEP, PEP & PEP-in-Pocket ("PIP") offer strong, flexible protection.
A "buffet" approach lets people choose what best fits their lives.
tinyurl.com/2zkf3hak
World AIDS Day is on Dec. 1.
Since 2004, global deaths have been in decline due to greater access to diagnostics, treatment & prevention.
This hard-won progress is now at risk due to major cuts to global public health.
We can't afford to go backward.
Since 2004, global deaths have been in decline due to greater access to diagnostics, treatment & prevention.
This hard-won progress is now at risk due to major cuts to global public health.
We can't afford to go backward.
November 25, 2025 at 2:32 PM
World AIDS Day is on Dec. 1.
Since 2004, global deaths have been in decline due to greater access to diagnostics, treatment & prevention.
This hard-won progress is now at risk due to major cuts to global public health.
We can't afford to go backward.
Since 2004, global deaths have been in decline due to greater access to diagnostics, treatment & prevention.
This hard-won progress is now at risk due to major cuts to global public health.
We can't afford to go backward.
More data outlining how COVID vaccines reduce the risk of hospitalizations & death, especially among those aged 65 and older.
This aligns nicely with recommendations from Canada's National Advisory Committee on Immunization. 🇨🇦
Link: tinyurl.com/yuwmmtt4 by Hansen et al.
This aligns nicely with recommendations from Canada's National Advisory Committee on Immunization. 🇨🇦
Link: tinyurl.com/yuwmmtt4 by Hansen et al.
November 20, 2025 at 6:10 PM
More data outlining how COVID vaccines reduce the risk of hospitalizations & death, especially among those aged 65 and older.
This aligns nicely with recommendations from Canada's National Advisory Committee on Immunization. 🇨🇦
Link: tinyurl.com/yuwmmtt4 by Hansen et al.
This aligns nicely with recommendations from Canada's National Advisory Committee on Immunization. 🇨🇦
Link: tinyurl.com/yuwmmtt4 by Hansen et al.
Reposted by Isaac Bogoch
Mutations in #H3N2 #flu viruses have some experts worried we're facing a second bad #influenza season. The new variant, subclade K, may be able to escape antibodies generated by previous infections or this year's flu shot. But some experts are hedging their bets. www.statnews.com/2025/11/20/f...
Is a bad flu season on the way? Experts see reason to be anxious
There are early indications that this flu season could be a bad one.
www.statnews.com
November 20, 2025 at 1:44 PM
Mutations in #H3N2 #flu viruses have some experts worried we're facing a second bad #influenza season. The new variant, subclade K, may be able to escape antibodies generated by previous infections or this year's flu shot. But some experts are hedging their bets. www.statnews.com/2025/11/20/f...
Reposted by Isaac Bogoch
Update on the wild #polio discovery in Germany: The virus was found in wastewater in Hamburg. @rki.de, the German public health agency, says the virus sequence is very similar to some isolated in Afghanistan, so the likely source was an infected human. (page 10 here: www.rki.de/DE/Aktuelles...)
www.rki.de
November 13, 2025 at 1:04 PM
Update on the wild #polio discovery in Germany: The virus was found in wastewater in Hamburg. @rki.de, the German public health agency, says the virus sequence is very similar to some isolated in Afghanistan, so the likely source was an infected human. (page 10 here: www.rki.de/DE/Aktuelles...)
Someone in Germany is shedding poliovirus - a crippling disease which should be eradicated.
This is another stark reminder of the risks we face when global vaccination coverage slips.
Link: tinyurl.com/y8t73dyc
This is another stark reminder of the risks we face when global vaccination coverage slips.
Link: tinyurl.com/y8t73dyc
November 13, 2025 at 1:26 PM
Someone in Germany is shedding poliovirus - a crippling disease which should be eradicated.
This is another stark reminder of the risks we face when global vaccination coverage slips.
Link: tinyurl.com/y8t73dyc
This is another stark reminder of the risks we face when global vaccination coverage slips.
Link: tinyurl.com/y8t73dyc
Exciting to see a new compound showing promise against malaria.
As drug resistance grows, mosquito ranges expand & public health resources remain limited, the need for new treatments has never been greater.
tinyurl.com/42wb2efe by @kakape.bsky.social
.
As drug resistance grows, mosquito ranges expand & public health resources remain limited, the need for new treatments has never been greater.
tinyurl.com/42wb2efe by @kakape.bsky.social
.
November 13, 2025 at 12:40 PM
Exciting to see a new compound showing promise against malaria.
As drug resistance grows, mosquito ranges expand & public health resources remain limited, the need for new treatments has never been greater.
tinyurl.com/42wb2efe by @kakape.bsky.social
.
As drug resistance grows, mosquito ranges expand & public health resources remain limited, the need for new treatments has never been greater.
tinyurl.com/42wb2efe by @kakape.bsky.social
.
Canada has lost its measles elimination status...a sad milestone.
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
November 10, 2025 at 2:20 PM
Canada has lost its measles elimination status...a sad milestone.
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Now is the time to double down on lowering barriers to routine childhood immunizations and ensuring Canadians have access to credible, science-based information.
Link: tinyurl.com/c8nfxvk3
Influenza cases are climbing in Canada.
Flu shots are widely available, and can help lower the chance of infection and hospitalization.
Below are this year’s flu trends (arrow) vs. the past three years.
Flu shots are widely available, and can help lower the chance of infection and hospitalization.
Below are this year’s flu trends (arrow) vs. the past three years.
November 4, 2025 at 9:11 PM
Influenza cases are climbing in Canada.
Flu shots are widely available, and can help lower the chance of infection and hospitalization.
Below are this year’s flu trends (arrow) vs. the past three years.
Flu shots are widely available, and can help lower the chance of infection and hospitalization.
Below are this year’s flu trends (arrow) vs. the past three years.
Antimicrobial resistance kills over a million people yearly.
I joined colleagues before the House of Commons Committee on Science & Research to discuss how Canada can help fight this threat.
Local action matters but global coordination is essential. 🇨🇦
➡️ tinyurl.com/3sfdvzt2
I joined colleagues before the House of Commons Committee on Science & Research to discuss how Canada can help fight this threat.
Local action matters but global coordination is essential. 🇨🇦
➡️ tinyurl.com/3sfdvzt2
October 30, 2025 at 8:24 AM
Antimicrobial resistance kills over a million people yearly.
I joined colleagues before the House of Commons Committee on Science & Research to discuss how Canada can help fight this threat.
Local action matters but global coordination is essential. 🇨🇦
➡️ tinyurl.com/3sfdvzt2
I joined colleagues before the House of Commons Committee on Science & Research to discuss how Canada can help fight this threat.
Local action matters but global coordination is essential. 🇨🇦
➡️ tinyurl.com/3sfdvzt2
@paulsaxmd.bsky.social knocks it out of the park with his analysis on 2 new COVID vaccine studies.
If you want data, nuance & common sense, have a read.
Key takeaway: COVID vaccine makes sense for those at greatest risk for severe infection (eg. elderly).
Link: tinyurl.com/yc63e9c2
If you want data, nuance & common sense, have a read.
Key takeaway: COVID vaccine makes sense for those at greatest risk for severe infection (eg. elderly).
Link: tinyurl.com/yc63e9c2
October 28, 2025 at 12:45 PM
@paulsaxmd.bsky.social knocks it out of the park with his analysis on 2 new COVID vaccine studies.
If you want data, nuance & common sense, have a read.
Key takeaway: COVID vaccine makes sense for those at greatest risk for severe infection (eg. elderly).
Link: tinyurl.com/yc63e9c2
If you want data, nuance & common sense, have a read.
Key takeaway: COVID vaccine makes sense for those at greatest risk for severe infection (eg. elderly).
Link: tinyurl.com/yc63e9c2
Attending the Global Conference on Biological Threat Reduction in Geneva with colleagues from around the world to strengthen strategies against infectious disease outbreaks, whether natural, accidental, or deliberate. Great to see Canada taking a leadership role in this sphere.🇨🇦
October 28, 2025 at 9:58 AM
Attending the Global Conference on Biological Threat Reduction in Geneva with colleagues from around the world to strengthen strategies against infectious disease outbreaks, whether natural, accidental, or deliberate. Great to see Canada taking a leadership role in this sphere.🇨🇦
The southern hemisphere offers an imperfect but useful preview of our flu season, and they had a tough one: High case numbers & lower vaccine uptake among those most at risk.
Flu shots in Ontario for high risk folks are available now & to the general public starting next week.
Flu shots in Ontario for high risk folks are available now & to the general public starting next week.
October 21, 2025 at 2:12 PM
The southern hemisphere offers an imperfect but useful preview of our flu season, and they had a tough one: High case numbers & lower vaccine uptake among those most at risk.
Flu shots in Ontario for high risk folks are available now & to the general public starting next week.
Flu shots in Ontario for high risk folks are available now & to the general public starting next week.
A locally acquired case of Chikungunya virus in New York State? This is a first.
Chikungunya is a mosquito-transmitted infection that can cause impressive (and sometimes lasting) joint pain and inflammation.
Link: tinyurl.com/57ue229x
Chikungunya is a mosquito-transmitted infection that can cause impressive (and sometimes lasting) joint pain and inflammation.
Link: tinyurl.com/57ue229x
October 16, 2025 at 12:03 PM
A locally acquired case of Chikungunya virus in New York State? This is a first.
Chikungunya is a mosquito-transmitted infection that can cause impressive (and sometimes lasting) joint pain and inflammation.
Link: tinyurl.com/57ue229x
Chikungunya is a mosquito-transmitted infection that can cause impressive (and sometimes lasting) joint pain and inflammation.
Link: tinyurl.com/57ue229x
New 🇨🇦 data in @cmaj.ca (from BC) showing relatively strong population-level measles immunity.
Outbreaks are likely to be more focal in under-vaccinated groups.
Some age cohorts are still <90% immune, so maintaining high vaccine coverage remains key.
Link: tinyurl.com/4tz5eftj
Outbreaks are likely to be more focal in under-vaccinated groups.
Some age cohorts are still <90% immune, so maintaining high vaccine coverage remains key.
Link: tinyurl.com/4tz5eftj
October 14, 2025 at 1:13 PM
New 🇨🇦 data in @cmaj.ca (from BC) showing relatively strong population-level measles immunity.
Outbreaks are likely to be more focal in under-vaccinated groups.
Some age cohorts are still <90% immune, so maintaining high vaccine coverage remains key.
Link: tinyurl.com/4tz5eftj
Outbreaks are likely to be more focal in under-vaccinated groups.
Some age cohorts are still <90% immune, so maintaining high vaccine coverage remains key.
Link: tinyurl.com/4tz5eftj