Grace Choung, MD 박영이
@gracechoung.bsky.social
Renal pathologist @CedarsSinai
#renalpath #kidneydisease
opinions are my own
#renalpath #kidneydisease
opinions are my own
Reposted by Grace Choung, MD 박영이
FREE #RenalPath Cryoglobulinemic glomerulonephritis (GN) is caused by intracapillary, capillary wall (often subendothelial), and mesangial cryoglobulin deposits, giving a membranoproliferative pattern of injury
bit.ly/498FKET
bit.ly/498FKET
December 28, 2025 at 5:00 PM
FREE #RenalPath Cryoglobulinemic glomerulonephritis (GN) is caused by intracapillary, capillary wall (often subendothelial), and mesangial cryoglobulin deposits, giving a membranoproliferative pattern of injury
bit.ly/498FKET
bit.ly/498FKET
Reposted by Grace Choung, MD 박영이
A very rare cause of oliguric acute kidney disease: crescentic C3 glomerulopathy Open Access
#nephsky #nephrology
academic.oup.com/omcr/article...
#nephsky #nephrology
academic.oup.com/omcr/article...
A very rare cause of oliguric acute kidney disease: crescentic C3 glomerulopathy
AbstractBackground. Crescentic glomerulonephritis, which is mostly recognized due to lupus nephritis, anti-neutrophil cytoplasmic antibody-associated vascu
academic.oup.com
December 29, 2025 at 6:07 PM
A very rare cause of oliguric acute kidney disease: crescentic C3 glomerulopathy Open Access
#nephsky #nephrology
academic.oup.com/omcr/article...
#nephsky #nephrology
academic.oup.com/omcr/article...
Reposted by Grace Choung, MD 박영이
Identification of Potential FSGS through Evaluation of Parietal Epithelial Cells Status Changes Using Integrin α3 Immunostaining
#nephsky #nephrology
www.sciencedirect.com/science/arti...
#nephsky #nephrology
www.sciencedirect.com/science/arti...
Identification of Potential FSGS through Evaluation of Parietal Epithelial Cells Status Changes Using Integrin α3 Immunostaining
Diagnosing primary focal segmental glomerulosclerosis (FSGS) remains challenging due to the lack of reliable biomarkers. This study investigates Integ…
www.sciencedirect.com
December 29, 2025 at 6:14 PM
Identification of Potential FSGS through Evaluation of Parietal Epithelial Cells Status Changes Using Integrin α3 Immunostaining
#nephsky #nephrology
www.sciencedirect.com/science/arti...
#nephsky #nephrology
www.sciencedirect.com/science/arti...
Reposted by Grace Choung, MD 박영이
Complement activation drives a compartmentalized innate immune response in C3 glomerulopathy contributing to the disease phenotype
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
December 30, 2025 at 3:15 PM
Complement activation drives a compartmentalized innate immune response in C3 glomerulopathy contributing to the disease phenotype
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
Reposted by Grace Choung, MD 박영이
Woman, 71 yo, allopurinol user, U-Sed: Uric acid crystals.
*First time I've seen crystals; How beautiful these crystals are! 😍 can't imagine how excited I am. Maybe only a few will understand 🤭 Happy New Year 2026! May there be more urinary sediments to explore
#urinarysediment #urinarymicroscopy
*First time I've seen crystals; How beautiful these crystals are! 😍 can't imagine how excited I am. Maybe only a few will understand 🤭 Happy New Year 2026! May there be more urinary sediments to explore
#urinarysediment #urinarymicroscopy
December 31, 2025 at 11:46 PM
Woman, 71 yo, allopurinol user, U-Sed: Uric acid crystals.
*First time I've seen crystals; How beautiful these crystals are! 😍 can't imagine how excited I am. Maybe only a few will understand 🤭 Happy New Year 2026! May there be more urinary sediments to explore
#urinarysediment #urinarymicroscopy
*First time I've seen crystals; How beautiful these crystals are! 😍 can't imagine how excited I am. Maybe only a few will understand 🤭 Happy New Year 2026! May there be more urinary sediments to explore
#urinarysediment #urinarymicroscopy
Reposted by Grace Choung, MD 박영이
#renalpath Dense deposit disease with mesangial proliferation, double contours of glomerular basement membrane (GBM), and cellular interposition, without evident eosinophilic immune complex–type deposits.
bit.ly/49zgtoR (FREE)
bit.ly/49zgtoR (FREE)
January 4, 2026 at 5:00 PM
#renalpath Dense deposit disease with mesangial proliferation, double contours of glomerular basement membrane (GBM), and cellular interposition, without evident eosinophilic immune complex–type deposits.
bit.ly/49zgtoR (FREE)
bit.ly/49zgtoR (FREE)
Reposted by Grace Choung, MD 박영이
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
January 3, 2026 at 8:29 PM
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
Reposted by Grace Choung, MD 박영이
REGISTRATION REMINDER
Register now for the 6th International Renal Pathology Conference, held on February 11-14, 2026 in Antigua, Guatemala
To register: renalpathsoc.org/6thIRPC
On behalf of the 6thIRPC Organizing Committee
#renalpath #nephsky #pathsky #nephrology
Register now for the 6th International Renal Pathology Conference, held on February 11-14, 2026 in Antigua, Guatemala
To register: renalpathsoc.org/6thIRPC
On behalf of the 6thIRPC Organizing Committee
#renalpath #nephsky #pathsky #nephrology
December 29, 2025 at 10:16 PM
REGISTRATION REMINDER
Register now for the 6th International Renal Pathology Conference, held on February 11-14, 2026 in Antigua, Guatemala
To register: renalpathsoc.org/6thIRPC
On behalf of the 6thIRPC Organizing Committee
#renalpath #nephsky #pathsky #nephrology
Register now for the 6th International Renal Pathology Conference, held on February 11-14, 2026 in Antigua, Guatemala
To register: renalpathsoc.org/6thIRPC
On behalf of the 6thIRPC Organizing Committee
#renalpath #nephsky #pathsky #nephrology
Kappa-type light chain proximal tubulopathy
On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance.
🔹Congo-red is negative
🔹Reported w/ MGUS, MM, & lymphoma
🔹Most had fanconi syndrome
#MGRS #renalpath #pathsky #nephsky #nephrology
(1/2)
On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance.
🔹Congo-red is negative
🔹Reported w/ MGUS, MM, & lymphoma
🔹Most had fanconi syndrome
#MGRS #renalpath #pathsky #nephsky #nephrology
(1/2)
December 26, 2025 at 10:36 PM
Kappa-type light chain proximal tubulopathy
On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance.
🔹Congo-red is negative
🔹Reported w/ MGUS, MM, & lymphoma
🔹Most had fanconi syndrome
#MGRS #renalpath #pathsky #nephsky #nephrology
(1/2)
On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance.
🔹Congo-red is negative
🔹Reported w/ MGUS, MM, & lymphoma
🔹Most had fanconi syndrome
#MGRS #renalpath #pathsky #nephsky #nephrology
(1/2)
Reposted by Grace Choung, MD 박영이
Characterizing the #NIH #Activity and #Chronicity Indices in 2 Independent #LupusNephritis Cohorts
#VisualAbstract by Denisse Arellano
https://www.kireports.org/article/S2468-0249(25)00696-5/fulltext
#VisualAbstract by Denisse Arellano
https://www.kireports.org/article/S2468-0249(25)00696-5/fulltext
December 19, 2025 at 12:00 AM
Characterizing the #NIH #Activity and #Chronicity Indices in 2 Independent #LupusNephritis Cohorts
#VisualAbstract by Denisse Arellano
https://www.kireports.org/article/S2468-0249(25)00696-5/fulltext
#VisualAbstract by Denisse Arellano
https://www.kireports.org/article/S2468-0249(25)00696-5/fulltext
Reposted by Grace Choung, MD 박영이
C3 glomerulopathy (C3G) & immune complex-mediated membranoproliferative glomerulonephritis are on a spectrum of glomerular disease. Read this Original Article on pegcetacoplan for idiopathic & familial pediatric C3G. Open Access
link.springer.com/article/10.1...
link.springer.com/article/10.1...
December 19, 2025 at 12:07 AM
C3 glomerulopathy (C3G) & immune complex-mediated membranoproliferative glomerulonephritis are on a spectrum of glomerular disease. Read this Original Article on pegcetacoplan for idiopathic & familial pediatric C3G. Open Access
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Grace Choung, MD 박영이
Obesity‑related glomerulopathy, A growing kidney burden in the obesity pandemic ca. 2025 from @jzrenalpath.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/41410808/
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/41410808/
December 18, 2025 at 11:26 PM
Obesity‑related glomerulopathy, A growing kidney burden in the obesity pandemic ca. 2025 from @jzrenalpath.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/41410808/
#Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/41410808/
Commentary
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
December 19, 2025 at 5:01 AM
Reposted by Grace Choung, MD 박영이
Save the date October 5-9, 2026 for the Joint Banff Foundation for Transplant Pathology and Alberta Transplant Institute Meeting in Banff, Alberta, Canada.
More details to come!
#renalpath #transplant #pathsky #nephsky #nephrology
More details to come!
#renalpath #transplant #pathsky #nephsky #nephrology
December 17, 2025 at 4:20 AM
Save the date October 5-9, 2026 for the Joint Banff Foundation for Transplant Pathology and Alberta Transplant Institute Meeting in Banff, Alberta, Canada.
More details to come!
#renalpath #transplant #pathsky #nephsky #nephrology
More details to come!
#renalpath #transplant #pathsky #nephsky #nephrology
Reposted by Grace Choung, MD 박영이
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Recording now available
Video on-demand link renalpathsoc.org/page-1075896
#renalpath #transplant #nephsky #pathsky #nephrology
Recording now available
Video on-demand link renalpathsoc.org/page-1075896
#renalpath #transplant #nephsky #pathsky #nephrology
December 16, 2025 at 4:04 AM
Spectrum of Transplant Rejection: Towards the Implementation of Activity and Chronicity Indices
Recording now available
Video on-demand link renalpathsoc.org/page-1075896
#renalpath #transplant #nephsky #pathsky #nephrology
Recording now available
Video on-demand link renalpathsoc.org/page-1075896
#renalpath #transplant #nephsky #pathsky #nephrology
Reposted by Grace Choung, MD 박영이
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
December 6, 2025 at 9:09 PM
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
Reposted by Grace Choung, MD 박영이
#UrinarySediment from a pt with #AKI #RPGN due to suspected MPO-AAV-GN inspected with Sternheimer-Malbin stain: RBC cast (bright field), WBC cast (oblique illumination), fibrinous cast (dark field), and renal tub epi cell cast (oblique). #OchsnerNephrology
November 22, 2025 at 9:22 PM
#UrinarySediment from a pt with #AKI #RPGN due to suspected MPO-AAV-GN inspected with Sternheimer-Malbin stain: RBC cast (bright field), WBC cast (oblique illumination), fibrinous cast (dark field), and renal tub epi cell cast (oblique). #OchsnerNephrology
Reposted by Grace Choung, MD 박영이
Bx for progressive CKD in a pt with CML, in remission. Limited biopsy with prominent debris filled proximal tubule lysosomes + for lysozyme (no evidence for light chain restriction (F/P) or chromogranin). Suspicious for lysozyme nephropathy. #renalpath #pathksy #nephsky
December 4, 2025 at 6:22 PM
Bx for progressive CKD in a pt with CML, in remission. Limited biopsy with prominent debris filled proximal tubule lysosomes + for lysozyme (no evidence for light chain restriction (F/P) or chromogranin). Suspicious for lysozyme nephropathy. #renalpath #pathksy #nephsky
Reposted by Grace Choung, MD 박영이
Kidney Tertiary #LymphoidTissues and Poor #Immunosuppressive Response in #IgANephropathy #IgAN
#VisualAbstract by Elba Medina
https://www.kireports.org/article/S2468-0249(25)00677-1/fulltext
#VisualAbstract by Elba Medina
https://www.kireports.org/article/S2468-0249(25)00677-1/fulltext
December 3, 2025 at 2:00 PM
Kidney Tertiary #LymphoidTissues and Poor #Immunosuppressive Response in #IgANephropathy #IgAN
#VisualAbstract by Elba Medina
https://www.kireports.org/article/S2468-0249(25)00677-1/fulltext
#VisualAbstract by Elba Medina
https://www.kireports.org/article/S2468-0249(25)00677-1/fulltext
Reposted by Grace Choung, MD 박영이
One of the more subtle cases of amyloidosis I have seen. Few spicules on silver stain. Minimal congo red positivity. Despite early amyloid deposition, pt had nephrotic syndrome. Likely AL type (pt has LPL); MS pending. #renalpath #pathsky #nephsky
December 3, 2025 at 5:05 PM
One of the more subtle cases of amyloidosis I have seen. Few spicules on silver stain. Minimal congo red positivity. Despite early amyloid deposition, pt had nephrotic syndrome. Likely AL type (pt has LPL); MS pending. #renalpath #pathsky #nephsky
Reposted by Grace Choung, MD 박영이
🚨 New paper alert in @asnpublications.bsky.social ⬇️
🔑 Preimplantation Histopathologic Assessment of Deceased Donor Kidneys.
Recommendations from the Banff Time-Zero Biopsy Working Group
‼️ Potential/Pitfalls/Future Research
🔗 journals.lww.com/jasn/abstrac...
🔑 Preimplantation Histopathologic Assessment of Deceased Donor Kidneys.
Recommendations from the Banff Time-Zero Biopsy Working Group
‼️ Potential/Pitfalls/Future Research
🔗 journals.lww.com/jasn/abstrac...
journals.lww.com
December 1, 2025 at 9:07 PM
🚨 New paper alert in @asnpublications.bsky.social ⬇️
🔑 Preimplantation Histopathologic Assessment of Deceased Donor Kidneys.
Recommendations from the Banff Time-Zero Biopsy Working Group
‼️ Potential/Pitfalls/Future Research
🔗 journals.lww.com/jasn/abstrac...
🔑 Preimplantation Histopathologic Assessment of Deceased Donor Kidneys.
Recommendations from the Banff Time-Zero Biopsy Working Group
‼️ Potential/Pitfalls/Future Research
🔗 journals.lww.com/jasn/abstrac...
Reposted by Grace Choung, MD 박영이
RPS and Banff Activity/Chronicity Working Group
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
November 28, 2025 at 8:15 PM
RPS and Banff Activity/Chronicity Working Group
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
WITH REGISTRATION LINK
us02web.zoom.us/webinar/regi...
#renalpath #pathsky #nephsky #nephrology
Reposted by Grace Choung, MD 박영이
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
November 26, 2025 at 11:51 PM
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
Reposted by Grace Choung, MD 박영이
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
November 24, 2025 at 9:13 PM
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
Reposted by Grace Choung, MD 박영이
Another interesting @kidneyint.bsky.social cohort study
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
November 23, 2025 at 1:53 PM
Another interesting @kidneyint.bsky.social cohort study
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky
www.kidney-international.org/article/S008...
Infection risk in kidney disease - lupus > ANCA, perhaps as ANCA is one and done (usually) whereas #lupus is never done?
Lupus > other primary and ADPKD is not surprising
#NephSky