Sanjay Mukhopadhyay
@smlungpathguy.bsky.social
I'm a pathologist (thoracic pathology), skeptic and opponent of groupthink
Pinned
#pathsky don't miss this amazing opportunity to learn from the best in the field, including the amazing Sean Williamson!
Reposted by Sanjay Mukhopadhyay
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
January 3, 2026 at 8:29 PM
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
Reposted by Sanjay Mukhopadhyay
Image of the Week!
Contributed by: Maria Tretiakova, M.D., Ph.D
Textbook topic: Kidney tumor
Diagnosis: TFEB rearranged RCC
Textbook topic link: www.pathologyoutlines.com/topic/kidney...
#Pathology #PathologyOutlines #PathSky
Contributed by: Maria Tretiakova, M.D., Ph.D
Textbook topic: Kidney tumor
Diagnosis: TFEB rearranged RCC
Textbook topic link: www.pathologyoutlines.com/topic/kidney...
#Pathology #PathologyOutlines #PathSky
January 7, 2026 at 7:04 PM
Image of the Week!
Contributed by: Maria Tretiakova, M.D., Ph.D
Textbook topic: Kidney tumor
Diagnosis: TFEB rearranged RCC
Textbook topic link: www.pathologyoutlines.com/topic/kidney...
#Pathology #PathologyOutlines #PathSky
Contributed by: Maria Tretiakova, M.D., Ph.D
Textbook topic: Kidney tumor
Diagnosis: TFEB rearranged RCC
Textbook topic link: www.pathologyoutlines.com/topic/kidney...
#Pathology #PathologyOutlines #PathSky
Reposted by Sanjay Mukhopadhyay
My first post on this platform. Hope I am not messing this up, but here it goes...
This is for neuroendocrino-philes here:
Excited to share the latest paper from our group on lung carcinoids.
onlinelibrary.wiley.com/doi/10.1111/...
pubmed.ncbi.nlm.nih.gov/41489019/
This is for neuroendocrino-philes here:
Excited to share the latest paper from our group on lung carcinoids.
onlinelibrary.wiley.com/doi/10.1111/...
pubmed.ncbi.nlm.nih.gov/41489019/
January 6, 2026 at 4:46 AM
My first post on this platform. Hope I am not messing this up, but here it goes...
This is for neuroendocrino-philes here:
Excited to share the latest paper from our group on lung carcinoids.
onlinelibrary.wiley.com/doi/10.1111/...
pubmed.ncbi.nlm.nih.gov/41489019/
This is for neuroendocrino-philes here:
Excited to share the latest paper from our group on lung carcinoids.
onlinelibrary.wiley.com/doi/10.1111/...
pubmed.ncbi.nlm.nih.gov/41489019/
Reposted by Sanjay Mukhopadhyay
The best thing you learn from the worst time of your life is that you get to see the true colors of everyone.
#Thoughtoftheday
#Wednesdaythought
#Thoughtoftheday
#Wednesdaythought
January 7, 2026 at 1:28 PM
The best thing you learn from the worst time of your life is that you get to see the true colors of everyone.
#Thoughtoftheday
#Wednesdaythought
#Thoughtoftheday
#Wednesdaythought
The countdown begins! Only 15 days to go!! I hear some folks are not only attending but staying for the full week! So much to do, great hotel, and great weather!
#pathsky
Register here:
www.clevelandclinicmeded.com/live/courses...
#pathsky
Register here:
www.clevelandclinicmeded.com/live/courses...
January 8, 2026 at 9:09 AM
The countdown begins! Only 15 days to go!! I hear some folks are not only attending but staying for the full week! So much to do, great hotel, and great weather!
#pathsky
Register here:
www.clevelandclinicmeded.com/live/courses...
#pathsky
Register here:
www.clevelandclinicmeded.com/live/courses...
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
January 3, 2026 at 8:29 PM
To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR)
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
#pathology #pulmpath #pathbugs #pathsky
To read how these fruiting bodies differ from those of Aspergillus, click here:
journals.sagepub.com/doi/10.1177/...
December 29, 2025 at 7:57 PM
Reposted by Sanjay Mukhopadhyay
Paracoccidioides venezuelensis dimorphism
November 3, 2025 at 1:26 AM
Paracoccidioides venezuelensis dimorphism
Reposted by Sanjay Mukhopadhyay
Direct examination with clorazol Black 400X of bronchial sample: hyaline hyphae suggestive of Aspergilosis
December 17, 2025 at 1:06 AM
Direct examination with clorazol Black 400X of bronchial sample: hyaline hyphae suggestive of Aspergilosis
Reposted by Sanjay Mukhopadhyay
“Worst drug ever. Makes you smell bad, kills you, and doesn’t get you high.”
November 23, 2025 at 4:34 AM
“Worst drug ever. Makes you smell bad, kills you, and doesn’t get you high.”
December 15, 2025 at 11:53 PM
Reposted by Sanjay Mukhopadhyay
Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭
December 6, 2025 at 5:28 AM
Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭
Reposted by Sanjay Mukhopadhyay
Mid-40’s male w/nasal obstruction
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
December 2, 2025 at 12:24 AM
Mid-40’s male w/nasal obstruction
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
December 6, 2025 at 9:09 PM
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded?
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
December 4, 2025 at 7:39 PM
This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded?
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Reposted by Sanjay Mukhopadhyay
Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm.
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
October 24, 2025 at 6:07 PM
Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm.
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Reposted by Sanjay Mukhopadhyay
📸 frozen section, tumor capsule
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
November 21, 2025 at 4:21 PM
📸 frozen section, tumor capsule
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
Reposted by Sanjay Mukhopadhyay
Frozen-section-Friday:
Adult with 2 cm parotid mass sent for intraoperative consultation
📸: solitary, largely circumscribed, cut surface w internal heterogeneity
📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix
📸: low mag nodule contour at frozen section
…next
#PathSky #ENTsky
Adult with 2 cm parotid mass sent for intraoperative consultation
📸: solitary, largely circumscribed, cut surface w internal heterogeneity
📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix
📸: low mag nodule contour at frozen section
…next
#PathSky #ENTsky
November 21, 2025 at 3:40 PM
Reposted by Sanjay Mukhopadhyay
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
November 24, 2025 at 9:13 PM
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
Reposted by Sanjay Mukhopadhyay
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
November 26, 2025 at 11:51 PM
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
Reposted by Sanjay Mukhopadhyay
Thanksgiving reminder… ⚖️
November 26, 2025 at 4:12 PM
Thanksgiving reminder… ⚖️
Reposted by Sanjay Mukhopadhyay
Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.
November 25, 2025 at 12:23 PM
Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.
Reposted by Sanjay Mukhopadhyay
We also have one of the largest repositories of veterinary gross pathology images freely available as well:
davisthompsonfoundation.org/noahs-arkive/
davisthompsonfoundation.org/noahs-arkive/
Noah’s Arkive – The Davis-Thompson Foundation
davisthompsonfoundation.org
November 25, 2025 at 1:16 PM
We also have one of the largest repositories of veterinary gross pathology images freely available as well:
davisthompsonfoundation.org/noahs-arkive/
davisthompsonfoundation.org/noahs-arkive/
Reposted by Sanjay Mukhopadhyay
Such a nice case! Thank you for sharing your expertise!
Cryptococcus can be diagnosed with high accuracy in surgical pathology or cytology specimens
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
November 25, 2025 at 1:19 PM
Such a nice case! Thank you for sharing your expertise!