Sanjay Mukhopadhyay
@smlungpathguy.bsky.social
I'm a pathologist (thoracic pathology), skeptic and opponent of groupthink
Pinned
#pathsky don't miss this amazing opportunity to learn from the best in the field, including the amazing Sean Williamson!
December 29, 2025 at 7:57 PM
Reposted by Sanjay Mukhopadhyay
Paracoccidioides venezuelensis dimorphism
November 3, 2025 at 1:26 AM
Paracoccidioides venezuelensis dimorphism
Reposted by Sanjay Mukhopadhyay
Direct examination with clorazol Black 400X of bronchial sample: hyaline hyphae suggestive of Aspergilosis
December 17, 2025 at 1:06 AM
Direct examination with clorazol Black 400X of bronchial sample: hyaline hyphae suggestive of Aspergilosis
Reposted by Sanjay Mukhopadhyay
“Worst drug ever. Makes you smell bad, kills you, and doesn’t get you high.”
November 23, 2025 at 4:34 AM
“Worst drug ever. Makes you smell bad, kills you, and doesn’t get you high.”
December 15, 2025 at 11:53 PM
Reposted by Sanjay Mukhopadhyay
Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭
December 6, 2025 at 5:28 AM
Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭
Reposted by Sanjay Mukhopadhyay
Mid-40’s male w/nasal obstruction
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
December 2, 2025 at 12:24 AM
Mid-40’s male w/nasal obstruction
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
Dx: allergic fungal sinusitis (polyps not shown)
📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells
📸 Charcot-Leyden crystals (arrows)
📸 occasionally fungal forms visible on H&E (arrow)
📸 fungus readily highlights w/GMS
#PathSky
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
December 6, 2025 at 9:09 PM
This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong?
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
#pathsky #idpath
Read more here in @IJSPjournal :
journals.sagepub.com/doi/10.1177/...
This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded?
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
December 4, 2025 at 7:39 PM
This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded?
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Read more here in Int J Surg Pathol:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #idsky #pathology #pulmpath
Reposted by Sanjay Mukhopadhyay
Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm.
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
October 24, 2025 at 6:07 PM
Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm.
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Access the rest of the clinical history and more via the link in comments.
#Pathology #PathologyOutlines #PathSky
Reposted by Sanjay Mukhopadhyay
📸 frozen section, tumor capsule
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
November 21, 2025 at 4:21 PM
📸 frozen section, tumor capsule
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
📸 frozen section, epithelial cells (ducts) and myoepithelial cells
📸 frozen section, nests of myoepithelial cells in myxochondroid matrix
Dx: pleomorphic adenoma
#Pathsky
Reposted by Sanjay Mukhopadhyay
Frozen-section-Friday:
Adult with 2 cm parotid mass sent for intraoperative consultation
📸: solitary, largely circumscribed, cut surface w internal heterogeneity
📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix
📸: low mag nodule contour at frozen section
…next
#PathSky #ENTsky
Adult with 2 cm parotid mass sent for intraoperative consultation
📸: solitary, largely circumscribed, cut surface w internal heterogeneity
📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix
📸: low mag nodule contour at frozen section
…next
#PathSky #ENTsky
November 21, 2025 at 3:40 PM
Reposted by Sanjay Mukhopadhyay
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
November 24, 2025 at 9:13 PM
Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6
#pathsky #pathology #CAPGuidelines
#pathsky #pathology #CAPGuidelines
Reposted by Sanjay Mukhopadhyay
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
November 26, 2025 at 11:51 PM
So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky
Reposted by Sanjay Mukhopadhyay
Thanksgiving reminder… ⚖️
November 26, 2025 at 4:12 PM
Thanksgiving reminder… ⚖️
Reposted by Sanjay Mukhopadhyay
Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.
November 25, 2025 at 12:23 PM
Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.
Reposted by Sanjay Mukhopadhyay
We also have one of the largest repositories of veterinary gross pathology images freely available as well:
davisthompsonfoundation.org/noahs-arkive/
davisthompsonfoundation.org/noahs-arkive/
Noah’s Arkive – The Davis-Thompson Foundation
davisthompsonfoundation.org
November 25, 2025 at 1:16 PM
We also have one of the largest repositories of veterinary gross pathology images freely available as well:
davisthompsonfoundation.org/noahs-arkive/
davisthompsonfoundation.org/noahs-arkive/
Reposted by Sanjay Mukhopadhyay
Such a nice case! Thank you for sharing your expertise!
Cryptococcus can be diagnosed with high accuracy in surgical pathology or cytology specimens
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
Case 5, Table 1
#pathology #pathsky
Read the paper!
journals.sagepub.com/doi/10.1177/...
November 25, 2025 at 1:19 PM
Such a nice case! Thank you for sharing your expertise!
Reposted by Sanjay Mukhopadhyay
We see those!
Mucicarmine highlights these beautifully.
Mucicarmine highlights these beautifully.
Digital Slide Viewer – The Davis-Thompson Foundation
davisthompsonfoundation.org
November 22, 2025 at 12:52 PM
We see those!
Mucicarmine highlights these beautifully.
Mucicarmine highlights these beautifully.
#pathsky #pathology #pulmpath
3 thoracic pathologists discuss pathology of mesothelioma
youtu.be/LVXlir8s8ik?...
3 thoracic pathologists discuss pathology of mesothelioma
youtu.be/LVXlir8s8ik?...
Pathology of mesothelioma (featuring biphasic mesothelioma and talc pleurodesis)
YouTube video by Sanjay Mukhopadhyay
youtu.be
November 24, 2025 at 2:45 PM
#pathsky #pathology #pulmpath
3 thoracic pathologists discuss pathology of mesothelioma
youtu.be/LVXlir8s8ik?...
3 thoracic pathologists discuss pathology of mesothelioma
youtu.be/LVXlir8s8ik?...
KikoXP + WSI + videoconferencing + 3 subspecialty experts = new way to educate
#pathsky
youtu.be/LVXlir8s8ik?...
#pathsky
youtu.be/LVXlir8s8ik?...
Pathology of mesothelioma (featuring biphasic mesothelioma and talc pleurodesis)
YouTube video by Sanjay Mukhopadhyay
youtu.be
November 22, 2025 at 7:19 PM
KikoXP + WSI + videoconferencing + 3 subspecialty experts = new way to educate
#pathsky
youtu.be/LVXlir8s8ik?...
#pathsky
youtu.be/LVXlir8s8ik?...
Reposted by Sanjay Mukhopadhyay
#ImageOfTheWeek ¦ The Fungal Superhighway 🧫
Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways.
📸 Dr Vanessa Francis, MRC Centre for Medical Mycology
#FungalInfection #Mycology #Science
Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways.
📸 Dr Vanessa Francis, MRC Centre for Medical Mycology
#FungalInfection #Mycology #Science
November 21, 2025 at 1:40 PM
#ImageOfTheWeek ¦ The Fungal Superhighway 🧫
Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways.
📸 Dr Vanessa Francis, MRC Centre for Medical Mycology
#FungalInfection #Mycology #Science
Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways.
📸 Dr Vanessa Francis, MRC Centre for Medical Mycology
#FungalInfection #Mycology #Science
Fungal hyphae are more tricky to diagnose by pathology alone than yeasts
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
November 22, 2025 at 2:30 PM
Fungal hyphae are more tricky to diagnose by pathology alone than yeasts
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
See detailed discussion here:
journals.sagepub.com/doi/10.1177/...
#pathsky #fungal #pathology
Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience!
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...
November 22, 2025 at 2:21 PM
Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience!
journals.sagepub.com/doi/10.1177/...
journals.sagepub.com/doi/10.1177/...