Kidney International
@kidneyint.bsky.social
Welcome to the official Bluesky account for Kidney International!
The Official Journal of the International Society of Nephrology
@ISNKidneyCare
https://www.kidney-international.org/
The Official Journal of the International Society of Nephrology
@ISNKidneyCare
https://www.kidney-international.org/
Uremia and parathyroid hormone have distinct effects on bone protein and gene expression
doi.org/10.1016/j.kint.2025.12.025
#NephSky #MedSky #osteoporosis
doi.org/10.1016/j.kint.2025.12.025
#NephSky #MedSky #osteoporosis
January 29, 2026 at 6:17 PM
Uremia and parathyroid hormone have distinct effects on bone protein and gene expression
doi.org/10.1016/j.kint.2025.12.025
#NephSky #MedSky #osteoporosis
doi.org/10.1016/j.kint.2025.12.025
#NephSky #MedSky #osteoporosis
Parasympathetic nerves in the kidney pelvis contribute to blood pressure regulation
doi.org/10.1016/j.kint.2026.01.002
#OpenAccess #NephSky #MedSky
doi.org/10.1016/j.kint.2026.01.002
#OpenAccess #NephSky #MedSky
January 29, 2026 at 6:05 PM
Parasympathetic nerves in the kidney pelvis contribute to blood pressure regulation
doi.org/10.1016/j.kint.2026.01.002
#OpenAccess #NephSky #MedSky
doi.org/10.1016/j.kint.2026.01.002
#OpenAccess #NephSky #MedSky
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy
doi.org/10.1016/j.kint.2026.01.001
#OpenAccess #NephSky #MedSky
doi.org/10.1016/j.kint.2026.01.001
#OpenAccess #NephSky #MedSky
January 29, 2026 at 5:54 PM
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy
doi.org/10.1016/j.kint.2026.01.001
#OpenAccess #NephSky #MedSky
doi.org/10.1016/j.kint.2026.01.001
#OpenAccess #NephSky #MedSky
Sodium glucose transporter 2 inhibition maintains kidney antibacterial response by decreasing complement C1q
doi.org/10.1016/j.kint.2026.01.003
#OpenAccess #NephSky #MedSky #inflammation #pyelonephritis
doi.org/10.1016/j.kint.2026.01.003
#OpenAccess #NephSky #MedSky #inflammation #pyelonephritis
January 29, 2026 at 5:36 PM
Sodium glucose transporter 2 inhibition maintains kidney antibacterial response by decreasing complement C1q
doi.org/10.1016/j.kint.2026.01.003
#OpenAccess #NephSky #MedSky #inflammation #pyelonephritis
doi.org/10.1016/j.kint.2026.01.003
#OpenAccess #NephSky #MedSky #inflammation #pyelonephritis
Executive Summary of the KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in Chronic Kidney Disease (CKD)
doi.org/10.1016/j.kint.2025.06.005
#NephSky #MedSky #OpenAccess #CKD #chronickidneydisease #anemia #KDIGO #dialysis
doi.org/10.1016/j.kint.2025.06.005
#NephSky #MedSky #OpenAccess #CKD #chronickidneydisease #anemia #KDIGO #dialysis
January 16, 2026 at 10:00 PM
Executive Summary of the KDIGO 2026 Clinical Practice Guideline for the Management of Anemia in Chronic Kidney Disease (CKD)
doi.org/10.1016/j.kint.2025.06.005
#NephSky #MedSky #OpenAccess #CKD #chronickidneydisease #anemia #KDIGO #dialysis
doi.org/10.1016/j.kint.2025.06.005
#NephSky #MedSky #OpenAccess #CKD #chronickidneydisease #anemia #KDIGO #dialysis
Commentary
Toward precision immunotherapy in nephrology: 1 step forward
Nicola M Tomas
doi.org/10.1016/j.kint.2025.10.007
Original article: doi.org/10.1016/j.kint.2025.09.028
#NephSky #MedSky #autoimmunity #kidney
Toward precision immunotherapy in nephrology: 1 step forward
Nicola M Tomas
doi.org/10.1016/j.kint.2025.10.007
Original article: doi.org/10.1016/j.kint.2025.09.028
#NephSky #MedSky #autoimmunity #kidney
January 16, 2026 at 9:58 PM
Commentary
Toward precision immunotherapy in nephrology: 1 step forward
Nicola M Tomas
doi.org/10.1016/j.kint.2025.10.007
Original article: doi.org/10.1016/j.kint.2025.09.028
#NephSky #MedSky #autoimmunity #kidney
Toward precision immunotherapy in nephrology: 1 step forward
Nicola M Tomas
doi.org/10.1016/j.kint.2025.10.007
Original article: doi.org/10.1016/j.kint.2025.09.028
#NephSky #MedSky #autoimmunity #kidney
Nephrology Image
Atypical presentation of granulomatosis with polyangiitis mimicking metastatic breast cancer
doi.org/10.1016/j.kint.2025.06.025
#NephSky #MedSky #AKI #PathSky
Atypical presentation of granulomatosis with polyangiitis mimicking metastatic breast cancer
doi.org/10.1016/j.kint.2025.06.025
#NephSky #MedSky #AKI #PathSky
January 16, 2026 at 9:50 PM
Nephrology Image
Atypical presentation of granulomatosis with polyangiitis mimicking metastatic breast cancer
doi.org/10.1016/j.kint.2025.06.025
#NephSky #MedSky #AKI #PathSky
Atypical presentation of granulomatosis with polyangiitis mimicking metastatic breast cancer
doi.org/10.1016/j.kint.2025.06.025
#NephSky #MedSky #AKI #PathSky
Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease
doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #OpenAccess #chronickidneydisease #egfr #CKD
doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #OpenAccess #chronickidneydisease #egfr #CKD
January 16, 2026 at 9:45 PM
Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease
doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #OpenAccess #chronickidneydisease #egfr #CKD
doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #OpenAccess #chronickidneydisease #egfr #CKD
Nephrology Image
Bilateral intrarenal aneurysms in anti-GBM/ANCA overlap syndrome
doi.org/10.1016/j.kint.2025.05.038
#MedSky #NephSky
Bilateral intrarenal aneurysms in anti-GBM/ANCA overlap syndrome
doi.org/10.1016/j.kint.2025.05.038
#MedSky #NephSky
January 7, 2026 at 4:57 PM
Nephrology Image
Bilateral intrarenal aneurysms in anti-GBM/ANCA overlap syndrome
doi.org/10.1016/j.kint.2025.05.038
#MedSky #NephSky
Bilateral intrarenal aneurysms in anti-GBM/ANCA overlap syndrome
doi.org/10.1016/j.kint.2025.05.038
#MedSky #NephSky
Nephrology Image
Lateral geniculate body hemorrhage in pediatric hemolytic uremic syndrome
doi.org/10.1016/j.kint.2025.06.024
#MedSky #NephSky #AKI #acutekidneyinjury
Lateral geniculate body hemorrhage in pediatric hemolytic uremic syndrome
doi.org/10.1016/j.kint.2025.06.024
#MedSky #NephSky #AKI #acutekidneyinjury
January 7, 2026 at 4:52 PM
Nephrology Image
Lateral geniculate body hemorrhage in pediatric hemolytic uremic syndrome
doi.org/10.1016/j.kint.2025.06.024
#MedSky #NephSky #AKI #acutekidneyinjury
Lateral geniculate body hemorrhage in pediatric hemolytic uremic syndrome
doi.org/10.1016/j.kint.2025.06.024
#MedSky #NephSky #AKI #acutekidneyinjury
Editorial: Special Report
SGLT-2 inhibition in pediatric CKD: advances, challenges, and opportunities
doi.org/10.1016/j.ki...
#NephSky #MedSky #OPenAccess #ckd #SGLT2i
SGLT-2 inhibition in pediatric CKD: advances, challenges, and opportunities
doi.org/10.1016/j.ki...
#NephSky #MedSky #OPenAccess #ckd #SGLT2i
January 7, 2026 at 4:43 PM
Editorial: Special Report
SGLT-2 inhibition in pediatric CKD: advances, challenges, and opportunities
doi.org/10.1016/j.ki...
#NephSky #MedSky #OPenAccess #ckd #SGLT2i
SGLT-2 inhibition in pediatric CKD: advances, challenges, and opportunities
doi.org/10.1016/j.ki...
#NephSky #MedSky #OPenAccess #ckd #SGLT2i
Mechanistic insights from transcript analysis of long-term pig to non-human primate kidney xenografts
doi.org/10.1016/j.kint.2025.11.018
#MedSky #NephSky #PathSky #renalbiopsy #kidneybiopsy
@harvardmed.bsky.social
doi.org/10.1016/j.kint.2025.11.018
#MedSky #NephSky #PathSky #renalbiopsy #kidneybiopsy
@harvardmed.bsky.social
January 7, 2026 at 4:15 PM
Mechanistic insights from transcript analysis of long-term pig to non-human primate kidney xenografts
doi.org/10.1016/j.kint.2025.11.018
#MedSky #NephSky #PathSky #renalbiopsy #kidneybiopsy
@harvardmed.bsky.social
doi.org/10.1016/j.kint.2025.11.018
#MedSky #NephSky #PathSky #renalbiopsy #kidneybiopsy
@harvardmed.bsky.social
Parathyroid hormone suppression profiles following oral calcium challenge in kidney transplant recipients
doi.org/10.1016/j.kint.2025.11.019
#NephSky #MedSky #OpenAccess
-Early calcium–PTH dynamics could define PT-HPT subtypes & 🔓 personalized treatment
doi.org/10.1016/j.kint.2025.11.019
#NephSky #MedSky #OpenAccess
-Early calcium–PTH dynamics could define PT-HPT subtypes & 🔓 personalized treatment
January 6, 2026 at 7:04 PM
Parathyroid hormone suppression profiles following oral calcium challenge in kidney transplant recipients
doi.org/10.1016/j.kint.2025.11.019
#NephSky #MedSky #OpenAccess
-Early calcium–PTH dynamics could define PT-HPT subtypes & 🔓 personalized treatment
doi.org/10.1016/j.kint.2025.11.019
#NephSky #MedSky #OpenAccess
-Early calcium–PTH dynamics could define PT-HPT subtypes & 🔓 personalized treatment
Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis
doi.org/10.1016/j.kint.2025.12.013
#MedSky #NephSky #glomerulardisease @bostonchildrens.bsky.social @brighamandwomens.bsky.social
doi.org/10.1016/j.kint.2025.12.013
#MedSky #NephSky #glomerulardisease @bostonchildrens.bsky.social @brighamandwomens.bsky.social
December 30, 2025 at 3:28 PM
Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis
doi.org/10.1016/j.kint.2025.12.013
#MedSky #NephSky #glomerulardisease @bostonchildrens.bsky.social @brighamandwomens.bsky.social
doi.org/10.1016/j.kint.2025.12.013
#MedSky #NephSky #glomerulardisease @bostonchildrens.bsky.social @brighamandwomens.bsky.social
Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction
doi.org/10.1016/j.kint.2025.12.011
#OpenAccess #MedSky #NephSky #AfricanTurquoisekillifish #SGLT2i
doi.org/10.1016/j.kint.2025.12.011
#OpenAccess #MedSky #NephSky #AfricanTurquoisekillifish #SGLT2i
December 30, 2025 at 3:22 PM
Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction
doi.org/10.1016/j.kint.2025.12.011
#OpenAccess #MedSky #NephSky #AfricanTurquoisekillifish #SGLT2i
doi.org/10.1016/j.kint.2025.12.011
#OpenAccess #MedSky #NephSky #AfricanTurquoisekillifish #SGLT2i
Therapeutic reprogramming of circulating myeloid cells via signal regulatory protein α extracellular vesicles in acute kidney injury
doi.org/10.1016/j.kint.2025.12.012
#NephSky #MedSky #AKI
doi.org/10.1016/j.kint.2025.12.012
#NephSky #MedSky #AKI
December 30, 2025 at 3:18 PM
Therapeutic reprogramming of circulating myeloid cells via signal regulatory protein α extracellular vesicles in acute kidney injury
doi.org/10.1016/j.kint.2025.12.012
#NephSky #MedSky #AKI
doi.org/10.1016/j.kint.2025.12.012
#NephSky #MedSky #AKI
Complement activation drives a compartmentalized innate immune response in C3 glomerulopathy contributing to the disease phenotype
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
December 30, 2025 at 3:15 PM
Complement activation drives a compartmentalized innate immune response in C3 glomerulopathy contributing to the disease phenotype
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
doi.org/10.1016/j.kint.2025.12.009
#NephSky #MedSky
A single-arm phase 2 trial of an investigational RNA therapeutic to complement factor B sefaxersen for treatment of IgA nephropathy
doi.org/10.1016/j.kint.2025.11.017
#OpenAccess #MedSky #NephSky #IgAN
doi.org/10.1016/j.kint.2025.11.017
#OpenAccess #MedSky #NephSky #IgAN
December 30, 2025 at 3:10 PM
A single-arm phase 2 trial of an investigational RNA therapeutic to complement factor B sefaxersen for treatment of IgA nephropathy
doi.org/10.1016/j.kint.2025.11.017
#OpenAccess #MedSky #NephSky #IgAN
doi.org/10.1016/j.kint.2025.11.017
#OpenAccess #MedSky #NephSky #IgAN
📣⭐New KI article type ⭐
Clinical Journey in Translational Medicine
Short feature highlighting patient cases that exemplify how bedside observations inform or are illuminated by mechanistic understanding.
🖥️Submissions now welcome!
➡️Details www.sciencedirect.com/journal/kidn...
#MedSky #NephSky
Clinical Journey in Translational Medicine
Short feature highlighting patient cases that exemplify how bedside observations inform or are illuminated by mechanistic understanding.
🖥️Submissions now welcome!
➡️Details www.sciencedirect.com/journal/kidn...
#MedSky #NephSky
Guide for authors - Kidney International® - ISSN 0085-2538 | ScienceDirect.com by Elsevier
Read the latest articles of Kidney International® at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
December 22, 2025 at 5:37 PM
📣⭐New KI article type ⭐
Clinical Journey in Translational Medicine
Short feature highlighting patient cases that exemplify how bedside observations inform or are illuminated by mechanistic understanding.
🖥️Submissions now welcome!
➡️Details www.sciencedirect.com/journal/kidn...
#MedSky #NephSky
Clinical Journey in Translational Medicine
Short feature highlighting patient cases that exemplify how bedside observations inform or are illuminated by mechanistic understanding.
🖥️Submissions now welcome!
➡️Details www.sciencedirect.com/journal/kidn...
#MedSky #NephSky
Minireview
Molecular pathways of kidney development and their applications to clinical research
doi.org/10.1016/j.kint.2025.09.032
#MedSky #MedSky #OpenAccess
Molecular pathways of kidney development and their applications to clinical research
doi.org/10.1016/j.kint.2025.09.032
#MedSky #MedSky #OpenAccess
December 18, 2025 at 5:59 PM
Minireview
Molecular pathways of kidney development and their applications to clinical research
doi.org/10.1016/j.kint.2025.09.032
#MedSky #MedSky #OpenAccess
Molecular pathways of kidney development and their applications to clinical research
doi.org/10.1016/j.kint.2025.09.032
#MedSky #MedSky #OpenAccess
Review
Severe #hypertension with thrombotic microangiopathy: the need for pathogenically targeted treatments
doi.org/10.1016/j.kint.2025.09.033
#MedSky #NephSky #OpenAccess @ucm.es
Severe #hypertension with thrombotic microangiopathy: the need for pathogenically targeted treatments
doi.org/10.1016/j.kint.2025.09.033
#MedSky #NephSky #OpenAccess @ucm.es
December 18, 2025 at 5:54 PM
Review
Severe #hypertension with thrombotic microangiopathy: the need for pathogenically targeted treatments
doi.org/10.1016/j.kint.2025.09.033
#MedSky #NephSky #OpenAccess @ucm.es
Severe #hypertension with thrombotic microangiopathy: the need for pathogenically targeted treatments
doi.org/10.1016/j.kint.2025.09.033
#MedSky #NephSky #OpenAccess @ucm.es
Commentary
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
December 16, 2025 at 7:07 PM
Commentary
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
Seeing the light (chains): a paradigm shift in PGNMID
Jean Hou and Mark Haas
doi.org/10.1016/j.kint.2025.09.018
Original article: doi.org/10.1016/j.kint.2025.07.039
#NephSky #MedSky #PathSky
Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD
doi.org/10.1016/j.kint.2025.12.004
#MedSky #NephSky #ADPKD #kidneydisease
doi.org/10.1016/j.kint.2025.12.004
#MedSky #NephSky #ADPKD #kidneydisease
December 16, 2025 at 4:29 PM
Aldehyde dehydrogenase 1 A1 regulates the transcription of PD-L1 and its targeting with disulfiram together with PD-L1 immunotherapy synergistically delays cyst growth in ADPKD
doi.org/10.1016/j.kint.2025.12.004
#MedSky #NephSky #ADPKD #kidneydisease
doi.org/10.1016/j.kint.2025.12.004
#MedSky #NephSky #ADPKD #kidneydisease
The m7G methyltransferase METTL1 promotes acute kidney inflammation by disrupting mitochondrial function
doi.org/10.1016/j.kint.2025.11.010
#NephSky #MedSky #AKI
doi.org/10.1016/j.kint.2025.11.010
#NephSky #MedSky #AKI
December 16, 2025 at 4:27 PM
The m7G methyltransferase METTL1 promotes acute kidney inflammation by disrupting mitochondrial function
doi.org/10.1016/j.kint.2025.11.010
#NephSky #MedSky #AKI
doi.org/10.1016/j.kint.2025.11.010
#NephSky #MedSky #AKI
Commentary
Berger disease redux
Richard J Glassock
doi.org/10.1016/j.kint.2025.09.021
Original article: doi.org/10.1016/j.kint.2025.07.038
#MedSky #NephSky
Berger disease redux
Richard J Glassock
doi.org/10.1016/j.kint.2025.09.021
Original article: doi.org/10.1016/j.kint.2025.07.038
#MedSky #NephSky
December 15, 2025 at 4:08 PM
Commentary
Berger disease redux
Richard J Glassock
doi.org/10.1016/j.kint.2025.09.021
Original article: doi.org/10.1016/j.kint.2025.07.038
#MedSky #NephSky
Berger disease redux
Richard J Glassock
doi.org/10.1016/j.kint.2025.09.021
Original article: doi.org/10.1016/j.kint.2025.07.038
#MedSky #NephSky