@vasculitides
@vasculitides.bsky.social
Living with EGPA/Churg-Strauss Syndrome • NIH-funded researcher • vasculitis patient advocate
www.vasculitides.com
www.vasculitides.com
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Access our new review on diagnosis, classification, and prognosis of ANCA-associated vasculitis in Nat Rev Rheum for free at rdcu.be/eL3wJ
Behcet's Disease Presenting With Large Intracavitary Thrombi and Pulmonary Embolism
Behçet's Disease Presenting With Large Intracavitary Thrombi and Pulmonary Embolism - PubMed
Behçet's disease (BD) is a rare chronic multisystem inflammatory disorder characterized by recurrent mucocutaneous, ocular, musculoskeletal, and vascular manifestations. Although vascular involvement is common, cardiac manifestations are exceptionally rare and can be life-threatening. We report a un …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 6:03 PM
Behcet's Disease Presenting With Large Intracavitary Thrombi and Pulmonary Embolism
Tavneos combo works as well as steroids for AAV remission
Tavneos combo works as well as steroids for AAV remission in trial
A Tavneos combination was similarly effective, with fewer side effects, to one with corticosteroids for ANCA-associated vasculitis remission.
ancavasculitisnews.com
November 5, 2025 at 6:02 PM
Tavneos combo works as well as steroids for AAV remission
You Never Think Enough About Giant Cell Arteritis
You Never Think Enough About Giant Cell Arteritis - PubMed
If PAMM and negative CRP are frequently encountered in "cranial GCA," "aortoarteritic GCA" is usually associated with inflammatory signs, which was not the case in this patient, reminding us that a high degree of suspicion should always be maintained in case of PAMM in elderly patients.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 6:02 PM
You Never Think Enough About Giant Cell Arteritis
Addressing clinical challenges in ANCA-associated vasculitis with real-world evidence
Addressing clinical challenges in ANCA-associated vasculitis with real-world evidence - PubMed
Key challenges in the management of anti-neutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) include the need to achieve more rapid and sustained remission, reduce exposure to glucocorticoids (GC), and reliably monitor and predict treatment response. Clinical trials in patients rece …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 6:01 PM
Addressing clinical challenges in ANCA-associated vasculitis with real-world evidence
METTL3-mediated m(6)A Methylation Modification Promotes the Endothelial Cell Pyroptosis in Kawasaki Disease
METTL3-mediated m6A Methylation Modification Promotes the Endothelial Cell Pyroptosis in Kawasaki Disease - PubMed
Kawasaki disease (KD) is classified as an acute febrile illness characterized primarily by systemic vasculitis. While the involvement of N6-methyladenosine (m<sup>6</sup>A) modification in various cardiovascular conditions has been established, its specific role in KD remains unexplored. This study …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 6:01 PM
METTL3-mediated m(6)A Methylation Modification Promotes the Endothelial Cell Pyroptosis in Kawasaki Disease
Boom or Bust: Clinical Trials in Pemphigus and Other B-Cell-Mediated Autoimmune Diseases
Boom or Bust: Clinical Trials in Pemphigus and Other B-Cell-Mediated Autoimmune Diseases - PubMed
Pemphigus vulgaris (PV) is a B-cell-mediated autoimmune blistering disease characterized by autoantibodies targeting skin cell adhesion proteins. Despite the well-defined pathophysiology and unmet need for safe and effective therapies for pemphigus, multiple therapeutics have failed to advance throu …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 6:00 PM
Boom or Bust: Clinical Trials in Pemphigus and Other B-Cell-Mediated Autoimmune Diseases
Central Nervous System Vasculitis Due to Ehrlichia canis in a Dog
Central Nervous System Vasculitis Due to Ehrlichia canis in a Dog - PubMed
A 4-year-old female neutered crossbreed dog was presented for a 2-month history of intermittent vestibulo-cerebellar ataxia and right head tilt. On admission, she presented clinical signs compatible with right paradoxical vestibular syndrome. Haematology showed moderate lymphocytosis, thrombocytopen …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:59 PM
Central Nervous System Vasculitis Due to Ehrlichia canis in a Dog
A Case Report of Bilateral Sequential Central Retinal Artery Occlusion in Occult Giant Cell Arteritis: The Eyes Are Windows to Systemic Disease
A Case Report of Bilateral Sequential Central Retinal Artery Occlusion in Occult Giant Cell Arteritis: The Eyes Are Windows to Systemic Disease - PubMed
Giant cell arteritis (GCA) is an inflammatory condition generally affecting medium to large arteries, commonly affecting the carotid artery and its branches. GCA generally presents with systemic symptoms such as temporal headache, jaw claudication, and polymyalgia rheumatica. Occult GCA is a variant …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:58 PM
A Case Report of Bilateral Sequential Central Retinal Artery Occlusion in Occult Giant Cell Arteritis: The Eyes Are Windows to Systemic Disease
Correction: A Case of Takayasu's Arteritis Presenting With Acute Middle Cerebral Artery Stroke Managed With Aortic-Common Carotid Artery (CCA) Bypass Surgery
Correction: A Case of Takayasu's Arteritis Presenting With Acute Middle Cerebral Artery Stroke Managed With Aortic-Common Carotid Artery (CCA) Bypass Surgery - PubMed
[This corrects the article DOI: 10.7759/cureus.48166.].
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:58 PM
Correction: A Case of Takayasu's Arteritis Presenting With Acute Middle Cerebral Artery Stroke Managed With Aortic-Common Carotid Artery (CCA) Bypass Surgery
Takayasu arteritis presenting with severe biventricular dysfunction and renal artery stenosis in a pediatric patient: a case report
Takayasu arteritis presenting with severe biventricular dysfunction and renal artery stenosis in a pediatric patient: a case report - PubMed
Pediatric TA with multi-organ involvement requires a coordinated, multidisciplinary approach for optimal outcomes. This case exemplifies the complexities of managing refractory hypertension and advanced vascular complications in TA and emphasizes the critical role of advanced interventional techniqu …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:58 PM
Takayasu arteritis presenting with severe biventricular dysfunction and renal artery stenosis in a pediatric patient: a case report
Role of multimodal monitoring in the anesthetic management of a patient with Takayasu's arteritis for neurosurgery
Role of multimodal monitoring in the anesthetic management of a patient with Takayasu's arteritis for neurosurgery - PubMed
Role of multimodal monitoring in the anesthetic management of a patient with Takayasu's arteritis for neurosurgery
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:57 PM
Role of multimodal monitoring in the anesthetic management of a patient with Takayasu's arteritis for neurosurgery
Kawasaki disease complicated with shock syndrome and macrophage activation syndrome in children: a case report
Kawasaki disease complicated with shock syndrome and macrophage activation syndrome in children: a case report - PubMed
Kawasaki disease (KD) is an acute self-limited vasculitis of unknown etiology. Clinically, a small proportion of patients may develop shock syndrome or macrophage activation syndrome (MAS); however, KD shock syndrome (KDSS) complicated by MAS is extremely rare. This article provides a detailed repor …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:57 PM
Kawasaki disease complicated with shock syndrome and macrophage activation syndrome in children: a case report
Intralesional rituximab injections for orbital granulomatosis with polyangiitis: a case series and literature review
Intralesional rituximab injections for orbital granulomatosis with polyangiitis: a case series and literature review - PubMed
Rituximab, an anti-CD-20 monoclonal antibody, has garnered increasing interest as a therapeutic option in orbital inflammatory disease (OID). We report our institutional experience with intralesional rituximab injections in two cases of orbital granulomatosis with polyangiitis (GPA), and additionall …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:56 PM
Intralesional rituximab injections for orbital granulomatosis with polyangiitis: a case series and literature review
Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review
Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review - PubMed
This case highlights the need for early serological testing for anti-GBM disease in RA patients with unexplained hematuria/proteinuria and for immunosuppressive therapy mindful of infection risk. Additionally, our literature review identified only ten reported cases of RA with anti-GBM disease, high …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:56 PM
Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review
Immune cell crosstalk between ANCA-associated vasculitis and IgG4-related disease: an unresolved pathogenic link
Immune cell crosstalk between ANCA-associated vasculitis and IgG4-related disease: an unresolved pathogenic link - PubMed
Immunoglobulin G4-related disease (IgG4-RD) is a rare, multisystemic fibro-inflammatory condition affecting various organs, including kidneys, lungs, nasal cavity, pancreas, salivary glands, and orbit. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAVs) is a multi-systemic infla …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:55 PM
Immune cell crosstalk between ANCA-associated vasculitis and IgG4-related disease: an unresolved pathogenic link
Comparison between primary and secondary central nervous system vasculitis in terms of clinical, biochemical, radiological, histopathological features, and outcomes: a single-center retrospective cohort study
Comparison between primary and secondary central nervous system vasculitis in terms of clinical, biochemical, radiological, histopathological features, and outcomes: a single-center retrospective cohort study - PubMed
In our study, PACNS patients presented more often with pseudotumoral lesions, seizures and small-vessel involvement and lymphocytic histologic pattern. WBC count ≤9.93×10<sup>3</sup>/mm<sup>3</sup> was an independent predictor of PACNS diagnosis.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:55 PM
Comparison between primary and secondary central nervous system vasculitis in terms of clinical, biochemical, radiological, histopathological features, and outcomes: a single-center retrospective cohort study
Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica
Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica - PubMed
We found that CT was high in patients with recent diagnosis of PMR and decreases significantly after 3 and 6 months of corticosteroid therapy. There is a 95% of concordance between CT and CRP as well as between CT and PMR activity scores. Our findings suggest that CT is useful as a noninvasive, imag …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:54 PM
Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica
Rapidly progressive relapsing polychondritis following surgery for lung adenocarcinoma: a case report
Rapidly progressive relapsing polychondritis following surgery for lung adenocarcinoma: a case report - PubMed
This case highlights the rare temporal correlation of RP as a paraneoplastic syndrome that can occur prior to or concurrently with tumor onset, but it may also arise following tumor resection. Because of the rarity and adverse consequences of RP, clinicians should improve their recognition of the di …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:54 PM
Rapidly progressive relapsing polychondritis following surgery for lung adenocarcinoma: a case report
Immunosuppression and Surgery-Free Interval in Granulomatosis With Polyangiitis Airway Stenosis
Immunosuppression and Surgery-Free Interval in Granulomatosis With Polyangiitis Airway Stenosis - PubMed
Rituximab may contribute to longer intervals between endoscopic airway intervention and delay relapse in GPA-related airway stenosis, supporting its role in stabilization of airway manifestations. Multidisciplinary management remains essential for this life-threatening GPA manifestation.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:53 PM
Immunosuppression and Surgery-Free Interval in Granulomatosis With Polyangiitis Airway Stenosis
Long-term effectiveness and safety of benralizumab in EGPA: a 3-year single-center experience
Long-term effectiveness and safety of benralizumab in EGPA: a 3-year single-center experience - PubMed
These findings support the long-term effectiveness and safety of benralizumab for EGPA, highlighting its role in inducing clinical remission, reducing corticosteroid dependence, and controlling disease activity.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:53 PM
Long-term effectiveness and safety of benralizumab in EGPA: a 3-year single-center experience
Anticoagulation-free VV-ECMO for a child with intractable pulmonary hemorrhage: A case report
Anticoagulation-free VV-ECMO for a child with intractable pulmonary hemorrhage: A case report - PubMed
IntroductionSystemic anticoagulation (AC) is standard practice in extracorporeal membrane oxygenation (ECMO). Adults on ECMO have been successfully managed AC-free. However, slower flow rates in pediatric circuits have mostly prevented this strategy. Thus, ECMO is often avoided in children with intr …
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:52 PM
Anticoagulation-free VV-ECMO for a child with intractable pulmonary hemorrhage: A case report
From Silicone to Synovitis: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) in Behcet's Disease
From Silicone to Synovitis: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) in Behçet's Disease - PubMed
From Silicone to Synovitis: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) in Behçet's Disease
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:52 PM
From Silicone to Synovitis: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) in Behcet's Disease
The clinical management of adult patients with Familial Mediterranean fever
The clinical management of adult patients with Familial Mediterranean fever - PubMed
The possibility of occurrence of FMF is not completely excluded in adult patients, despite it could be characterized by atypical or delayed-onset presentations. Thus, raising the awareness toward the disease is of critical importance in improving the outcome of these patients.
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:51 PM
The clinical management of adult patients with Familial Mediterranean fever
PPI Use and Its Significant Association With an Increased Incidence of Intestinal Behcet Disease
PPI Use and Its Significant Association With an Increased Incidence of Intestinal Behçet Disease - PubMed
PPI Use and Its Significant Association With an Increased Incidence of Intestinal Behçet Disease
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:51 PM
PPI Use and Its Significant Association With an Increased Incidence of Intestinal Behcet Disease
Development of Successive Thrombophlebitis and Takayasu Arteritis Associated With Crohn Disease in a Pediatric Patient: A Case Report
Development of Successive Thrombophlebitis and Takayasu Arteritis Associated With Crohn Disease in a Pediatric Patient: A Case Report - PubMed
Development of Successive Thrombophlebitis and Takayasu Arteritis Associated With Crohn Disease in a Pediatric Patient: A Case Report
pubmed.ncbi.nlm.nih.gov
November 5, 2025 at 5:50 PM
Development of Successive Thrombophlebitis and Takayasu Arteritis Associated With Crohn Disease in a Pediatric Patient: A Case Report