Joel Topf
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kidneyboy.bsky.social
Joel Topf
@kidneyboy.bsky.social
Saying the product of the kidneys is urine is like saying the product of a factory is pollution. Urine is a by-product. The product is homeostasis.

COI: https://pbfluids.com/about/
Reposted by Joel Topf
As one of the original flozinators it so maddening to see nephrologists flozinate *instead* of using immunosuppresants, dz modifying therapies in nonDM CKD. Consider a thought experiment in transplant: proteinuria is often how we pick up ABMR & an SGLT2i is the wrong answer. Now do IgAN, SLE,C3G etc
November 10, 2025 at 2:18 PM
Vlado up for Sibe in IgAN

With some new data and some old data
#KidneyWk
November 8, 2025 at 5:40 PM
Cui for a study of membranous with MIL62

#KidneyWk
November 8, 2025 at 5:21 PM
Reposted by Joel Topf
Richard Haynes- professor at Oxford, nephrologist. Senior author EMPA-k , 3C etc etc…..
November 8, 2025 at 5:05 PM
Laura Dember is the moderator and Richard somebody is the moderator for this late breaking and high impact clinical trial

#KidneyWk
November 8, 2025 at 4:32 PM
Amazing #KidneyWk run
November 8, 2025 at 1:53 PM
Reposted by Joel Topf
The #NephJC Freely Filtered podcast taping is kicking off! What are the best trials from #KidneyWk? You’ll have to listen to find out.
November 8, 2025 at 3:29 AM
Reposted by Joel Topf
Was listening to nephjc freely filtered episode of ACHIEVE trial just the other day. Of all the things we've tried in HD and failed, and now fish oil does the trick??? @kidneyboy.bsky.social @hswapnil.medsky.social
Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk

Simultaneous pub in NEJM

www.nejm.org/doi/full/10....
November 7, 2025 at 11:40 PM
If you are coming to the NephJC party tonight catch the bus at 7:00 at the corner Avenida De Las Americas & Rusk St at the corner of the conference center nearest Hall A. Near the restaurant, Grotto.
November 7, 2025 at 11:19 PM
Reposted by Joel Topf
Recall only a few years ago that the late breaking trials session often has post hoc observation analyses or another negative HD or AKI trial. Indeed it is fantastic. More tomorrow…
November 7, 2025 at 7:52 AM
Mid career award winners #KidneyWk
November 7, 2025 at 2:04 PM
Reposted by Joel Topf
I might have a new career in industry, but another #KidneyWk calls for another Kidney Week Run Club! From now on it will be organized by @nephjc.bsky.social (basically @kidneyboy.bsky.social). Saturday morning, 6:30 am, Discovery Green. 3 miles + change.
November 7, 2025 at 2:33 AM
Reposted by Joel Topf
Reposted by Joel Topf
ORIGIN phase 3 trial: In an interim analysis of a clinical trial, atacicept, a fusion protein that binds and inhibits two cytokines thought to be central to the pathophysiology of IgA nephropathy, significantly reduced proteinuria. nej.md/3JEq8QL

@asnkidney.bsky.social | #KidneyWk
November 6, 2025 at 2:55 PM
Reposted by Joel Topf
#NephJC at #KidneyWk
🔥🔥We have all sorts of events

🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun

🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃

For more info 👇👇
www.nephjc.com
NephJC
www.nephjc.com
November 5, 2025 at 8:15 PM
Reposted by Joel Topf
Hey #KidneyWk come find me in Houston for some free art 🖼️
(One per customer, taxes may apply, only valid 11/5-11/9, yada-yada-yada)
November 6, 2025 at 12:23 PM
Vlado is so interesting. I loved getting a chance to follow up on his state of the art lecture
Joel Topf @kidneyboy.bsky.social spoke with Vlado Perkovic following his #KidneyWk lecture on how we can cure kidney disease. Stay tuned to nephtimes.com for the video.
November 6, 2025 at 8:03 PM
Panel discussion. What's your limit

<8 Sterns
<8 Rondon
6 Fabrice

#KidneyWk
November 6, 2025 at 6:17 PM
If you ever get to give a plenary talk pay for the stock photo!

🤦🏻‍♂️

#KidneyWk
November 6, 2025 at 3:34 PM
You'd think insulin would make the list

#KidneyWk
November 6, 2025 at 3:31 PM
Up next a panel discussion about the trials #KidneyWk
November 6, 2025 at 3:21 PM
Next up in Richard Lafayette about Ataracept in IgAN #KidneyWk
November 6, 2025 at 3:08 PM
Reposted by Joel Topf
The answer is primary care access and cheap meds.
November 6, 2025 at 2:52 PM
First up Hiddo Heerspink on his birthday to talk about FINE-One

Finerenone in type DM 1

#KidneyWk
November 6, 2025 at 2:56 PM