Philip Ruthig
@philipruthig.bsky.social
Staff Scientist @erturklab.bsky.social, passionate neuroscientist, Light sheet microscopist, and Python aficionado.
Pinned
Philip Ruthig
@philipruthig.bsky.social
· Aug 21
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
Reposted by Philip Ruthig
❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ.
🔬: Miltenyi Ultramiscroscope
🥼: Pam Rios Coronado, @pamrc.bsky.social
🏛️: Red-Horse lab @stanford.edu
🎬: #syGlass
🔬: Miltenyi Ultramiscroscope
🥼: Pam Rios Coronado, @pamrc.bsky.social
🏛️: Red-Horse lab @stanford.edu
🎬: #syGlass
February 12, 2026 at 4:02 PM
❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ.
🔬: Miltenyi Ultramiscroscope
🥼: Pam Rios Coronado, @pamrc.bsky.social
🏛️: Red-Horse lab @stanford.edu
🎬: #syGlass
🔬: Miltenyi Ultramiscroscope
🥼: Pam Rios Coronado, @pamrc.bsky.social
🏛️: Red-Horse lab @stanford.edu
🎬: #syGlass
Reposted by Philip Ruthig
For the record, an earlier version of this post, using Fig 1 from this paper, but without shorts, fell foul of BlueSky's "Adult Content" filter.
Why is the human #penis unusually large compared to other primates? @upama.bsky.social @mikejennions.bsky.social &co show that #genital size is a cue for male-male assessment in humans, so #PenisSize likely evolved due to both female choice & male-male rivalry @plosbiology.org 🧪 plos.io/45tjF33
January 23, 2026 at 2:39 PM
For the record, an earlier version of this post, using Fig 1 from this paper, but without shorts, fell foul of BlueSky's "Adult Content" filter.
Come work with a great team on one of the big questions at Helmholtz Munich!
@helmholtzmunich.bsky.social
@helmholtzmunich.bsky.social
We are looking for a PhD student to join our project on developing AI-driven, whole-body multi-omics atlases of mammalian organisms:
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Helmholtz Munich hiring PhD Position – Deep Learning for Multi-Omics Atlases of the Mammalian Body in Greater Munich Metropolitan Area | LinkedIn
Posted 6:18:35 PM. AI Scientist - PhD Position Institute for Intelligent Biotechnologies (iBIO), Helmholtz Munich /…See this and similar jobs on LinkedIn.
www.linkedin.com
January 23, 2026 at 3:08 PM
Come work with a great team on one of the big questions at Helmholtz Munich!
@helmholtzmunich.bsky.social
@helmholtzmunich.bsky.social
Reposted by Philip Ruthig
X/Twitter's rough full volume is around 500 total million posts every day, or 182 (and a half) billion posts per year.
By contracts, we found 11.2 million research posts in all of 2025 on there.
In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.
By contracts, we found 11.2 million research posts in all of 2025 on there.
In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.
January 8, 2026 at 1:08 PM
X/Twitter's rough full volume is around 500 total million posts every day, or 182 (and a half) billion posts per year.
By contracts, we found 11.2 million research posts in all of 2025 on there.
In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.
By contracts, we found 11.2 million research posts in all of 2025 on there.
In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.
Reposted by Philip Ruthig
Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
go.nature.com
December 23, 2025 at 10:07 PM
Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC
Reposted by Philip Ruthig
Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
December 8, 2025 at 2:22 PM
Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
Reposted by Philip Ruthig
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
November 4, 2025 at 1:55 PM
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
Reposted by Philip Ruthig
💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00.
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
September 10, 2025 at 9:57 AM
💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00.
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
August 30, 2025 at 6:15 AM
Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good
Reposted by Philip Ruthig
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
August 22, 2025 at 8:15 AM
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
August 21, 2025 at 12:39 PM
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
August 21, 2025 at 11:49 AM
Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)
Reposted by Philip Ruthig
When a microscope facility user asks about how to make a red/green overlay
July 14, 2025 at 9:34 AM
When a microscope facility user asks about how to make a red/green overlay
Reposted by Philip Ruthig
Our spin-off company is hiring a COO. (Stay tuned for more job offers)
www.linkedin.com/jobs/view/42...
www.linkedin.com/jobs/view/42...
Deep Piction hiring Chief Operating Officer in Greater Munich Metropolitan Area | LinkedIn
Posted 10:54:20 AM. Chief Operating Officer (COO)Location: Munich, Germany (On-site) Employment Type: Full-timeAbout…See this and similar jobs on LinkedIn.
www.linkedin.com
June 23, 2025 at 6:53 AM
Our spin-off company is hiring a COO. (Stay tuned for more job offers)
www.linkedin.com/jobs/view/42...
www.linkedin.com/jobs/view/42...
Reposted by Philip Ruthig
June 21, 2025 at 11:43 AM
Reposted by Philip Ruthig
🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer!
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
June 11, 2025 at 8:26 AM
🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer!
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
Reposted by Philip Ruthig
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
May 30, 2025 at 5:32 AM
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
Signs I am, indeed, living in Munich, pt 1:
I just paid 9€ for a pretzel and croissant.
I just paid 9€ for a pretzel and croissant.
May 20, 2025 at 5:45 PM
Signs I am, indeed, living in Munich, pt 1:
I just paid 9€ for a pretzel and croissant.
I just paid 9€ for a pretzel and croissant.
Reposted by Philip Ruthig
+1000
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
This pattern is going to repeat in one domain after another, and gradually force us to admit that 60% of every job is networking, knowing who to trust, and doing poorly justified risk/benefit assessment.
The “AI Scientist” work, while interesting, sort of mischaracterizes the process of science as generating hypotheses and running experiments. The actual thing is so much more interesting: interpreting unclear evidence, reasoning about unsteady foundations, etc.
May 12, 2025 at 2:07 PM
+1000
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
Reposted by Philip Ruthig
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
May 3, 2025 at 1:44 PM
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
One of the undisputed scientific wins of the last few years.
On this day 2y ago we announced our move away from the huge profits that NeuroImage makes for Elsevier.
Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
April 17, 2025 at 9:55 AM
One of the undisputed scientific wins of the last few years.
Can wholeheartedly recommend the city, place and people to motivated to-be phd students! Don't hesitate to apply 👏👏
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Universität Leipzig: GRK Neurotune
www.lw.uni-leipzig.de
April 10, 2025 at 9:19 AM
Can wholeheartedly recommend the city, place and people to motivated to-be phd students! Don't hesitate to apply 👏👏
Reposted by Philip Ruthig
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Universität Leipzig: GRK Neurotune
www.lw.uni-leipzig.de
April 10, 2025 at 9:16 AM
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Reposted by Philip Ruthig
BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...
Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature Communications
There are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a ra...
www.nature.com
March 28, 2025 at 6:13 PM
BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...
When I see a notification about an editors email
New version of the fear response GIF :) #neuroskyence
March 24, 2025 at 7:28 AM
When I see a notification about an editors email