Philip Ruthig
@philipruthig.bsky.social
Staff Scientist @erturklab.bsky.social, passionate neuroscientist, Light sheet microscopist, and Python aficionado.
Reposted by Philip Ruthig
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
November 4, 2025 at 1:55 PM
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
Reposted by Philip Ruthig
💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00.
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
September 10, 2025 at 9:57 AM
💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00.
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
August 30, 2025 at 6:15 AM
Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good
Reposted by Philip Ruthig
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
August 22, 2025 at 8:15 AM
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
August 21, 2025 at 12:39 PM
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️
plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
August 21, 2025 at 11:49 AM
Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)
Reposted by Philip Ruthig
When a microscope facility user asks about how to make a red/green overlay
July 14, 2025 at 9:34 AM
When a microscope facility user asks about how to make a red/green overlay
Reposted by Philip Ruthig
Our spin-off company is hiring a COO. (Stay tuned for more job offers)
www.linkedin.com/jobs/view/42...
www.linkedin.com/jobs/view/42...
Deep Piction hiring Chief Operating Officer in Greater Munich Metropolitan Area | LinkedIn
Posted 10:54:20 AM. Chief Operating Officer (COO)Location: Munich, Germany (On-site) Employment Type: Full-timeAbout…See this and similar jobs on LinkedIn.
www.linkedin.com
June 23, 2025 at 6:53 AM
Our spin-off company is hiring a COO. (Stay tuned for more job offers)
www.linkedin.com/jobs/view/42...
www.linkedin.com/jobs/view/42...
Reposted by Philip Ruthig
June 21, 2025 at 11:43 AM
Reposted by Philip Ruthig
🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer!
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
June 11, 2025 at 8:26 AM
🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer!
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
💻 Build scalable #bioimaging solutions
🌍 Collaborate globally
🎯 Contribute to open science through #OME #Zarr
📣 Tell your #NGFF friends.
Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
Reposted by Philip Ruthig
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
May 30, 2025 at 5:32 AM
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
Signs I am, indeed, living in Munich, pt 1:
I just paid 9€ for a pretzel and croissant.
I just paid 9€ for a pretzel and croissant.
May 20, 2025 at 5:45 PM
Signs I am, indeed, living in Munich, pt 1:
I just paid 9€ for a pretzel and croissant.
I just paid 9€ for a pretzel and croissant.
Reposted by Philip Ruthig
+1000
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
This pattern is going to repeat in one domain after another, and gradually force us to admit that 60% of every job is networking, knowing who to trust, and doing poorly justified risk/benefit assessment.
The “AI Scientist” work, while interesting, sort of mischaracterizes the process of science as generating hypotheses and running experiments. The actual thing is so much more interesting: interpreting unclear evidence, reasoning about unsteady foundations, etc.
May 12, 2025 at 2:07 PM
+1000
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
Reposted by Philip Ruthig
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
May 3, 2025 at 1:44 PM
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
One of the undisputed scientific wins of the last few years.
On this day 2y ago we announced our move away from the huge profits that NeuroImage makes for Elsevier.
Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
April 17, 2025 at 9:55 AM
One of the undisputed scientific wins of the last few years.
Can wholeheartedly recommend the city, place and people to motivated to-be phd students! Don't hesitate to apply 👏👏
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Universität Leipzig: GRK Neurotune
www.lw.uni-leipzig.de
April 10, 2025 at 9:19 AM
Can wholeheartedly recommend the city, place and people to motivated to-be phd students! Don't hesitate to apply 👏👏
Reposted by Philip Ruthig
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Universität Leipzig: GRK Neurotune
www.lw.uni-leipzig.de
April 10, 2025 at 9:16 AM
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication!
📍 Start: Oct 1, 2025
🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig.
Apply now 👉 www.lw.uni-leipzig.de/en/institut-...
#NeuroTune
Reposted by Philip Ruthig
BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...
Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature Communications
There are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a ra...
www.nature.com
March 28, 2025 at 6:13 PM
BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...
When I see a notification about an editors email
New version of the fear response GIF :) #neuroskyence
March 24, 2025 at 7:28 AM
When I see a notification about an editors email
Reposted by Philip Ruthig
🌷Spring flowers? Fireworks?
Mouse cerebral cortex FFPE tissue was labeled with eight primary antibodies. Aluora Spatial Amplification Kits and DAPI were used for detection, followed by imaging on the EVOS S1000 Spatial Imaging System.
🧠🔬🧪 #Neuroscience #FluorescenceFriday
Mouse cerebral cortex FFPE tissue was labeled with eight primary antibodies. Aluora Spatial Amplification Kits and DAPI were used for detection, followed by imaging on the EVOS S1000 Spatial Imaging System.
🧠🔬🧪 #Neuroscience #FluorescenceFriday
March 21, 2025 at 5:27 AM
🌷Spring flowers? Fireworks?
Mouse cerebral cortex FFPE tissue was labeled with eight primary antibodies. Aluora Spatial Amplification Kits and DAPI were used for detection, followed by imaging on the EVOS S1000 Spatial Imaging System.
🧠🔬🧪 #Neuroscience #FluorescenceFriday
Mouse cerebral cortex FFPE tissue was labeled with eight primary antibodies. Aluora Spatial Amplification Kits and DAPI were used for detection, followed by imaging on the EVOS S1000 Spatial Imaging System.
🧠🔬🧪 #Neuroscience #FluorescenceFriday
Reposted by Philip Ruthig
Wegen großer Nachfrage haben wir nun die Rohdaten hinter "So hat Ihre Gemeinde gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... und "So hat Ihr Wahlkreis seit 1949 gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... auf Github frei zugänglich gemacht.
March 20, 2025 at 10:53 AM
Wegen großer Nachfrage haben wir nun die Rohdaten hinter "So hat Ihre Gemeinde gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... und "So hat Ihr Wahlkreis seit 1949 gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... auf Github frei zugänglich gemacht.
Reposted by Philip Ruthig
Looking for a suitable research software management tool for your PhD? 👨💻
Then take a look at the #openaccess lecture slides by @haesleinhuepf.bsky.social and get to know git[hub] to upgrade your software development.
👉 Check out the lecture slides here: zenodo.org/records/1462...
Then take a look at the #openaccess lecture slides by @haesleinhuepf.bsky.social and get to know git[hub] to upgrade your software development.
👉 Check out the lecture slides here: zenodo.org/records/1462...
March 19, 2025 at 10:31 AM
Looking for a suitable research software management tool for your PhD? 👨💻
Then take a look at the #openaccess lecture slides by @haesleinhuepf.bsky.social and get to know git[hub] to upgrade your software development.
👉 Check out the lecture slides here: zenodo.org/records/1462...
Then take a look at the #openaccess lecture slides by @haesleinhuepf.bsky.social and get to know git[hub] to upgrade your software development.
👉 Check out the lecture slides here: zenodo.org/records/1462...
Reposted by Philip Ruthig
👏👏👏 to the “woke max planck director” @davidpoeppel.bsky.social! “We’re living in a time and an environment in which there are certain shared values that are non-negotiable. And that includes sexist behavior, mobbing; harassment of any kind.”
March 13, 2025 at 10:29 PM
👏👏👏 to the “woke max planck director” @davidpoeppel.bsky.social! “We’re living in a time and an environment in which there are certain shared values that are non-negotiable. And that includes sexist behavior, mobbing; harassment of any kind.”
Reposted by Philip Ruthig
www.youtube.com/watch?v=n5nE...
Important and painful
Important and painful
How Germany's elite research institution fails young scientists | DW Documentary
YouTube video by DW Documentary
www.youtube.com
March 13, 2025 at 8:58 PM
www.youtube.com/watch?v=n5nE...
Important and painful
Important and painful
Reposted by Philip Ruthig
Maybe a good time to remember that mice have tiny hyperconnected brains. An estimated 97% of all possible connections between brain areas exist in mice, vs ~62% in macaques and marmosets.
No wonder everything is everywhere in mice, they have all-to-all connectivity!
doi.org/10.1093/cerc...
No wonder everything is everywhere in mice, they have all-to-all connectivity!
doi.org/10.1093/cerc...
January 11, 2025 at 4:37 PM
Maybe a good time to remember that mice have tiny hyperconnected brains. An estimated 97% of all possible connections between brain areas exist in mice, vs ~62% in macaques and marmosets.
No wonder everything is everywhere in mice, they have all-to-all connectivity!
doi.org/10.1093/cerc...
No wonder everything is everywhere in mice, they have all-to-all connectivity!
doi.org/10.1093/cerc...