Otrosdías
@otrosdias.bsky.social
For music go to: @otherdays.bsky.social
For COVID, public health, politics, etc.. stay here...
For COVID, public health, politics, etc.. stay here...
Reposted by Otrosdías
Vous voulez savoir si vous votre ado ou enfant'e devrait se vacciner contre la grippe et le covid ?
Est-ce que c'est vraiment nécessaire ?
On partage ci-dessous quelques articles scientifiques récents qui expliquent que la vaccination est sûre et apporte plus de bénéfices que de tomber malade.
⬇️
Est-ce que c'est vraiment nécessaire ?
On partage ci-dessous quelques articles scientifiques récents qui expliquent que la vaccination est sûre et apporte plus de bénéfices que de tomber malade.
⬇️
L'intérêt de la vaccination anti-Covid chez les enfants et adolescents se confirme
Faut-il vacciner les plus jeunes, chez qui les risques liés à l'infection par le SARS-CoV-2 apparaissent moindres que chez les personnes âgées ? Oui, répond une étude publiée dans la revue The Lancet ...
infectiologie.lequotidiendumedecin.fr
November 14, 2025 at 7:10 PM
Vous voulez savoir si vous votre ado ou enfant'e devrait se vacciner contre la grippe et le covid ?
Est-ce que c'est vraiment nécessaire ?
On partage ci-dessous quelques articles scientifiques récents qui expliquent que la vaccination est sûre et apporte plus de bénéfices que de tomber malade.
⬇️
Est-ce que c'est vraiment nécessaire ?
On partage ci-dessous quelques articles scientifiques récents qui expliquent que la vaccination est sûre et apporte plus de bénéfices que de tomber malade.
⬇️
Reposted by Otrosdías
The burden could be higher this year. But you’re not helpless. The combination of vaccination + masking + ventilation + staying home if sick + hygiene can make a big difference. Don’t wait until hospitals are overwhelmed.
PS - Get all of your shots if you haven't already!
PS - Get all of your shots if you haven't already!
November 14, 2025 at 12:02 PM
The burden could be higher this year. But you’re not helpless. The combination of vaccination + masking + ventilation + staying home if sick + hygiene can make a big difference. Don’t wait until hospitals are overwhelmed.
PS - Get all of your shots if you haven't already!
PS - Get all of your shots if you haven't already!
Reposted by Otrosdías
Let’s talk about why I am increasingly uneasy about the upcoming flu season. A new H3N2 influenza variant has been emerging globally, and it carries mutations linked to immune escape i.e the virus’s ability to bypass some of our pre-existing immunity. 🧵
utppublishing.com/doi/10.3138/...
utppublishing.com/doi/10.3138/...
Emergence of seasonal influenza A(H3N2) variants with immune escape potential warrants enhanced molecular and epidemiological surveillance for the 2025–2026 season | Journal of the Association of Medical Microbiology and Infectious Disease Canada
Background: All of the major antigenic changes in influenza A(H3N2) viruses since 1968 have involved mutations at just nine amino acid positions, called cluster transition sites, surrounding the receptor binding region of the hemagglutinin surface protein. During the northern hemisphere (NH) 2024–2025 influenza season, A(H3N2) variants emerged with multiple parallel substitutions affecting cluster transition sites 135, 145, 158 and/or 189, with implications for the 2025–2026 season. Methods: Using >24,000 global A(H3) sequences between September 2024 and August 2025, we assess the nature and frequency of amino acid mutations among emerging NH and southern hemisphere (SH) A(H3N2) variants relative to the 2024–2025 subclade J and updated 2025–2026 subclade J.2 vaccine reference strains. We contextualize based upon historic amino acid variation among >210,000 global A(H3) sequences since 1968 and publicly available antigenic characterization data relative to 2024–2025 and 2025–2026 vaccine reference strains Results: Virtually all circulating A(H3N2) viruses in 2024–2025 were subclade J.2. In Europe, about one-third had cluster transition site mutations, mostly T135A with S145N. In North America, more than two-thirds had cluster transition site mutations, including T135K or S145N, with late-season increase in doubly mutated J.2.3 (N158K + K189R) and J.2.5 (S145N + N158K) subclades. The SH 2025 season showed increase in J.2.3 and emergence of J.2.4 (T135K + K189R) including a further drifted J.2.4.1 variant with additional N158D and other mutations, recently renamed subclade K. A substantial proportion of J.2.3 and J.2.4 viruses are antigenically distinct from the 2025–2026 influenza vaccine. Conclusion: Influenza A(H3N2) variants with a combination of cluster transition site mutations emerged during the NH 2024–2025 season. A further drifted and vaccine-mismatched variant now called subclade K arose during the SH 2025 season and is projected to predominate among A(H3N2) viruses for the NH 2025–2026 season. While mismatched vaccines may still provide protection, enhanced genetic, antigenic and epidemiological (eg, vaccine effectiveness) monitoring are warranted to inform risk assessment and response.
utppublishing.com
November 14, 2025 at 12:02 PM
Let’s talk about why I am increasingly uneasy about the upcoming flu season. A new H3N2 influenza variant has been emerging globally, and it carries mutations linked to immune escape i.e the virus’s ability to bypass some of our pre-existing immunity. 🧵
utppublishing.com/doi/10.3138/...
utppublishing.com/doi/10.3138/...
Reposted by Otrosdías
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
LoCITT-T - Long COVID Treatment Trial
The Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID.
longcovid.scripps.edu
November 13, 2025 at 3:21 PM
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
Reposted by Otrosdías
England’s top medical unions warn it’s unacceptable that Long COVID still isn’t classed as an occupational disease.
Three years after official advice, frontline health workers are still waiting for recognition and financial support.
www.bma.org.uk/bma-media-ce...
Three years after official advice, frontline health workers are still waiting for recognition and financial support.
www.bma.org.uk/bma-media-ce...
‘Unconscionable’ that the Government has not recognised Long COVID as an occupational disease, warns BMA and RCN - BMA media centre - BMA
Press release from the BMA.
www.bma.org.uk
November 12, 2025 at 4:25 PM
England’s top medical unions warn it’s unacceptable that Long COVID still isn’t classed as an occupational disease.
Three years after official advice, frontline health workers are still waiting for recognition and financial support.
www.bma.org.uk/bma-media-ce...
Three years after official advice, frontline health workers are still waiting for recognition and financial support.
www.bma.org.uk/bma-media-ce...
Reposted by Otrosdías
Failure to formally recognise Covid-19 as an occupational disease places the continued delivery of long-term sick payments needed by so many workers on a precarious footing.
We support ICTU in their calls to formally classify Covid-19 as an occupational disease.
www.ictu.ie/news/governm...
We support ICTU in their calls to formally classify Covid-19 as an occupational disease.
www.ictu.ie/news/governm...
Government’s failure to recognise Covid-19 as occupational disease shows lessons from pandemic not being learned
The Irish Congress of Trade Unions has today (11 November) expressed its deep disappointment at the Government’s refusal to formally recognise Covid-19 as an occupational disease.
www.ictu.ie
November 13, 2025 at 8:18 AM
Failure to formally recognise Covid-19 as an occupational disease places the continued delivery of long-term sick payments needed by so many workers on a precarious footing.
We support ICTU in their calls to formally classify Covid-19 as an occupational disease.
www.ictu.ie/news/governm...
We support ICTU in their calls to formally classify Covid-19 as an occupational disease.
www.ictu.ie/news/governm...
"the neurological and neurodevelopmental aftermath of SARS-CoV-2 infection and its associated inflammatory syndromes pose complex challenges for pediatric health..." www.nature.com/articles/s41...
Neurological and neurodevelopmental effects of Covid and MIS-C on children - Pediatric Research
Pediatric Research - Neurological and neurodevelopmental effects of Covid and MIS-C on children
www.nature.com
November 13, 2025 at 7:17 AM
"the neurological and neurodevelopmental aftermath of SARS-CoV-2 infection and its associated inflammatory syndromes pose complex challenges for pediatric health..." www.nature.com/articles/s41...
Reposted by Otrosdías
New data from Japan adds evidence that COVID-19 may raise shingles risk.
The findings come from nearly 400,000 patients diagnosed with COVID-19 from 2020–2023, showing a higher incidence of shingles for a full 6 weeks after being infected with the SARS-CoV-2 virus.
Source: archive.li/hFsm4
The findings come from nearly 400,000 patients diagnosed with COVID-19 from 2020–2023, showing a higher incidence of shingles for a full 6 weeks after being infected with the SARS-CoV-2 virus.
Source: archive.li/hFsm4
November 13, 2025 at 4:00 AM
New data from Japan adds evidence that COVID-19 may raise shingles risk.
The findings come from nearly 400,000 patients diagnosed with COVID-19 from 2020–2023, showing a higher incidence of shingles for a full 6 weeks after being infected with the SARS-CoV-2 virus.
Source: archive.li/hFsm4
The findings come from nearly 400,000 patients diagnosed with COVID-19 from 2020–2023, showing a higher incidence of shingles for a full 6 weeks after being infected with the SARS-CoV-2 virus.
Source: archive.li/hFsm4
Reposted by Otrosdías
France: "Wearing a mask is once again mandatory in Paris hospitals"
"Faced with a rapid rise in respiratory infections, several hospitals in the Île-de-France region have decided to reinstate mandatory mask-wearing for healthcare workers, visitors, and patients over the age of 6."
archive.li/ZeKtJ
"Faced with a rapid rise in respiratory infections, several hospitals in the Île-de-France region have decided to reinstate mandatory mask-wearing for healthcare workers, visitors, and patients over the age of 6."
archive.li/ZeKtJ
November 12, 2025 at 8:02 AM
France: "Wearing a mask is once again mandatory in Paris hospitals"
"Faced with a rapid rise in respiratory infections, several hospitals in the Île-de-France region have decided to reinstate mandatory mask-wearing for healthcare workers, visitors, and patients over the age of 6."
archive.li/ZeKtJ
"Faced with a rapid rise in respiratory infections, several hospitals in the Île-de-France region have decided to reinstate mandatory mask-wearing for healthcare workers, visitors, and patients over the age of 6."
archive.li/ZeKtJ
Reposted by Otrosdías
Very good news in this preprint with real-world vaccine efficacy data from the current influenza epidemic in England:
The influenza vaccines appear to remain efficacious against the drifted H3N2 subclade K virus which is dominant in the English epidemic.
Caveat: Waning might lower effect.
The influenza vaccines appear to remain efficacious against the drifted H3N2 subclade K virus which is dominant in the English epidemic.
Caveat: Waning might lower effect.
November 12, 2025 at 6:45 AM
Very good news in this preprint with real-world vaccine efficacy data from the current influenza epidemic in England:
The influenza vaccines appear to remain efficacious against the drifted H3N2 subclade K virus which is dominant in the English epidemic.
Caveat: Waning might lower effect.
The influenza vaccines appear to remain efficacious against the drifted H3N2 subclade K virus which is dominant in the English epidemic.
Caveat: Waning might lower effect.
Reposted by Otrosdías
A Bumper Month for Covid Vaccines and More
It's been an eventful few weeks for Covid vaccines – mostly good, some very bad. Let's start with the good news. Novavax has transferred marketing of its protein subunit Covid vaccine in the EU and US to a major pharmaceutical company, Sanofi. Here's…
It's been an eventful few weeks for Covid vaccines – mostly good, some very bad. Let's start with the good news. Novavax has transferred marketing of its protein subunit Covid vaccine in the EU and US to a major pharmaceutical company, Sanofi. Here's…
A Bumper Month for Covid Vaccines and More
It's been an eventful few weeks for Covid vaccines – mostly good, some very bad. Let's start with the good news. Novavax has transferred marketing of its protein subunit Covid vaccine in the EU and US to a major pharmaceutical company, Sanofi. Here's hoping that leads to wider availability and economies of scale. Sanofi will also be able to use Novavax's patented adjuvant in new vaccines.
hildabastian.wordpress.com
November 12, 2025 at 7:38 AM
A Bumper Month for Covid Vaccines and More
It's been an eventful few weeks for Covid vaccines – mostly good, some very bad. Let's start with the good news. Novavax has transferred marketing of its protein subunit Covid vaccine in the EU and US to a major pharmaceutical company, Sanofi. Here's…
It's been an eventful few weeks for Covid vaccines – mostly good, some very bad. Let's start with the good news. Novavax has transferred marketing of its protein subunit Covid vaccine in the EU and US to a major pharmaceutical company, Sanofi. Here's…
Reposted by Otrosdías
This should be standard to health care facilities to prevent airborne nosocomial infections, anyway
Best practice is to manage airquality with ventilation, airfiltration, CO2 monitoring and N95 masking if available in addition to basic hygiene
Best practice is to manage airquality with ventilation, airfiltration, CO2 monitoring and N95 masking if available in addition to basic hygiene
IWK hospital to require visitors, patients to wear masks https://www.ctvnews.ca/atlantic/nova-scotia/article/iwk-health-centre-to-require-all-visitors-patients-to-wear-masks/
𝗚𝗲𝘁 𝘄𝗲𝗲𝗸𝗹𝘆 𝘂𝗽𝗱𝗮𝘁𝗲𝘀 ⇢ CanadaHealthwatch.ca/newsletter
𝗚𝗲𝘁 𝘄𝗲𝗲𝗸𝗹𝘆 𝘂𝗽𝗱𝗮𝘁𝗲𝘀 ⇢ CanadaHealthwatch.ca/newsletter
November 12, 2025 at 4:52 AM
This should be standard to health care facilities to prevent airborne nosocomial infections, anyway
Best practice is to manage airquality with ventilation, airfiltration, CO2 monitoring and N95 masking if available in addition to basic hygiene
Best practice is to manage airquality with ventilation, airfiltration, CO2 monitoring and N95 masking if available in addition to basic hygiene
Reposted by Otrosdías
Reposted by Otrosdías
Saline nasal sprays offer so much potential as a public health intervention to reduce viral illnesses. Easy to use, relatively cheap and widely available.
Congratulations to Professor Paul Little, winning Royal College of General Practitioners Research Paper of the Year 🌟
He and his team’s research found that simple nasal sprays, can shorten illness, ease symptoms and even reduce the need for antibiotics.
Read more 👉 https://tr.ee/P2bffM
He and his team’s research found that simple nasal sprays, can shorten illness, ease symptoms and even reduce the need for antibiotics.
Read more 👉 https://tr.ee/P2bffM
November 11, 2025 at 7:03 AM
Saline nasal sprays offer so much potential as a public health intervention to reduce viral illnesses. Easy to use, relatively cheap and widely available.
Reposted by Otrosdías
UK: You are “more likely” to catch COVID “indoors and in crowded places”, the NHS warns.
"Avoiding these areas where possible could help limit your chances of infection."
Source: archive.li/IfLIi
"Avoiding these areas where possible could help limit your chances of infection."
Source: archive.li/IfLIi
November 11, 2025 at 4:17 AM
UK: You are “more likely” to catch COVID “indoors and in crowded places”, the NHS warns.
"Avoiding these areas where possible could help limit your chances of infection."
Source: archive.li/IfLIi
"Avoiding these areas where possible could help limit your chances of infection."
Source: archive.li/IfLIi
Reposted by Otrosdías
I'm reading a history of the 1918 influenza in the US and learned that early work on the effectiveness of masking was rejected by the physicians at the time as quickly as they could get away with it. It's been a century. Time to accept the science or get out of the way. My angry account of the past:
No Question Left Unasked
www.tjradcliffe.com
November 11, 2025 at 7:06 AM
I'm reading a history of the 1918 influenza in the US and learned that early work on the effectiveness of masking was rejected by the physicians at the time as quickly as they could get away with it. It's been a century. Time to accept the science or get out of the way. My angry account of the past:
Reposted by Otrosdías
FINALLY, California public health🥑 got it right ✅. Now they show N95 as clearly superior b/c it has head-straps versus KN95/KF94, "They provide less protection than N95s because they have ear loops."
www.cdph.ca.gov/Programs/CID...
www.cdph.ca.gov/Programs/CID...
November 11, 2025 at 4:31 AM
FINALLY, California public health🥑 got it right ✅. Now they show N95 as clearly superior b/c it has head-straps versus KN95/KF94, "They provide less protection than N95s because they have ear loops."
www.cdph.ca.gov/Programs/CID...
www.cdph.ca.gov/Programs/CID...
Reposted by Otrosdías
Recent research in New Zealand shows that Long Covid sufferers feel let down by the health system:
"The picture painted by participants was bleak with a sense that the world had moved on from Covid-19 and left them behind."
www.rnz.co.nz/news/nationa...
#longcovid
"The picture painted by participants was bleak with a sense that the world had moved on from Covid-19 and left them behind."
www.rnz.co.nz/news/nationa...
#longcovid
Researchers say healthcare system failing long Covid patients
A researcher is calling on the government to provide dedicated funding for long Covid.
www.rnz.co.nz
November 7, 2025 at 3:48 AM
Recent research in New Zealand shows that Long Covid sufferers feel let down by the health system:
"The picture painted by participants was bleak with a sense that the world had moved on from Covid-19 and left them behind."
www.rnz.co.nz/news/nationa...
#longcovid
"The picture painted by participants was bleak with a sense that the world had moved on from Covid-19 and left them behind."
www.rnz.co.nz/news/nationa...
#longcovid
Reposted by Otrosdías
Many Long COVID trials have reported negative results in 2024 and 2025. In our Comment for @thelancetinfdis.bsky.social we argue that inadequate outcome measures might have played a role. (1/12)
November 8, 2025 at 12:08 AM
Many Long COVID trials have reported negative results in 2024 and 2025. In our Comment for @thelancetinfdis.bsky.social we argue that inadequate outcome measures might have played a role. (1/12)
Reposted by Otrosdías
From the Stanford Long COVID Clinic (CA, USA)
"indicates that a significant proportion of long COVID patients may experience sleep disturbances"
www.mdpi.com/2227-9032/13...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
"indicates that a significant proportion of long COVID patients may experience sleep disturbances"
www.mdpi.com/2227-9032/13...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
November 7, 2025 at 1:46 AM
From the Stanford Long COVID Clinic (CA, USA)
"indicates that a significant proportion of long COVID patients may experience sleep disturbances"
www.mdpi.com/2227-9032/13...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
"indicates that a significant proportion of long COVID patients may experience sleep disturbances"
www.mdpi.com/2227-9032/13...
Screenshot from latest Science for ME weekly update
#LongCovid #PASC
Reposted by Otrosdías
'Scientists reveal another piece in Long COVID puzzle'
'New study reveals a structural association between circulating microclots and neutrophil extracellular traps (NETs) in patients with Long COVID. When dysregulated, this interaction may become pathogenic'
www.eurekalert.org/news-release...
'New study reveals a structural association between circulating microclots and neutrophil extracellular traps (NETs) in patients with Long COVID. When dysregulated, this interaction may become pathogenic'
www.eurekalert.org/news-release...
Scientists reveal another piece in Long COVID puzzle
In patients with Long COVID, a new study has revealed structural association between circulating microclots and neutrophil extracellular traps (NETs). This finding suggests the existence of under...
www.eurekalert.org
November 10, 2025 at 7:45 PM
'Scientists reveal another piece in Long COVID puzzle'
'New study reveals a structural association between circulating microclots and neutrophil extracellular traps (NETs) in patients with Long COVID. When dysregulated, this interaction may become pathogenic'
www.eurekalert.org/news-release...
'New study reveals a structural association between circulating microclots and neutrophil extracellular traps (NETs) in patients with Long COVID. When dysregulated, this interaction may become pathogenic'
www.eurekalert.org/news-release...
Reposted by Otrosdías
A new @ca.theconversation.com article, co-authored by @juliamwright.bsky.social (FRSC), explores how updated CSA standards for respirator use can better protect health-care workers and patients — and why adopting evidence-based safety measures is vital for all Canadians. #RSCVoices
The CSA’s revised standard on respirators should help us all breathe easier
The CSA Group — a not-for-profit standards organization — released for review a new draft standard on the “Selection, Use, and Care of Respirators” (CSA Z94.4:25) for workplaces, specifically includin...
rsc-src.ca
November 10, 2025 at 5:13 PM
A new @ca.theconversation.com article, co-authored by @juliamwright.bsky.social (FRSC), explores how updated CSA standards for respirator use can better protect health-care workers and patients — and why adopting evidence-based safety measures is vital for all Canadians. #RSCVoices
Reposted by Otrosdías
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
November 7, 2025 at 4:00 PM
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
Reposted by Otrosdías
Newly published study offers hope to both males and females with #LongCovid - but in different ways 👇
It also explains why I don't have 'brain fog', but why my life is now like running a marathon on a flat battery.
Very useful.
www.cell.com/cell-reports...
#PostExertionalMalaise
It also explains why I don't have 'brain fog', but why my life is now like running a marathon on a flat battery.
Very useful.
www.cell.com/cell-reports...
#PostExertionalMalaise
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
Shahbaz et al. find that female long COVID patients with ME/CFS exhibit heightened
inflammation, altered hematopoiesis, disrupted hormone levels, and neuroinflammatory
gene signatures. In parallel, ou...
www.cell.com
November 8, 2025 at 8:49 AM
Newly published study offers hope to both males and females with #LongCovid - but in different ways 👇
It also explains why I don't have 'brain fog', but why my life is now like running a marathon on a flat battery.
Very useful.
www.cell.com/cell-reports...
#PostExertionalMalaise
It also explains why I don't have 'brain fog', but why my life is now like running a marathon on a flat battery.
Very useful.
www.cell.com/cell-reports...
#PostExertionalMalaise
Reposted by Otrosdías
2/2
- Phase 2 trial for intranasal vax in the US
- In Australia, a trial for a pancoronavirus version of one of the internationally-approved Covid vaxes
- More preclinical reports show prevention of transmission &/or durability
- a shelf-stable mucosal vax.
absolutelymaybe.plos.org/2025/11/06/a...
- Phase 2 trial for intranasal vax in the US
- In Australia, a trial for a pancoronavirus version of one of the internationally-approved Covid vaxes
- More preclinical reports show prevention of transmission &/or durability
- a shelf-stable mucosal vax.
absolutelymaybe.plos.org/2025/11/06/a...
A Bumper Update on Next Generation Covid Vaccines (No 34) - Absolutely Maybe
This was always going to be a big month, with results from clinical trials of 2 vaccines, as well as 3 new…
absolutelymaybe.plos.org
November 6, 2025 at 10:55 PM
2/2
- Phase 2 trial for intranasal vax in the US
- In Australia, a trial for a pancoronavirus version of one of the internationally-approved Covid vaxes
- More preclinical reports show prevention of transmission &/or durability
- a shelf-stable mucosal vax.
absolutelymaybe.plos.org/2025/11/06/a...
- Phase 2 trial for intranasal vax in the US
- In Australia, a trial for a pancoronavirus version of one of the internationally-approved Covid vaxes
- More preclinical reports show prevention of transmission &/or durability
- a shelf-stable mucosal vax.
absolutelymaybe.plos.org/2025/11/06/a...