Evan Zeitler
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littlebiggloms.bsky.social
Evan Zeitler
@littlebiggloms.bsky.social
1.1K followers 580 following 170 posts
Nephrologist #NephSky | Flozinator | Obesity, diet and Kidney metabolism | Husband, father of twins+one | @UNCKidney but views my own
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Reposted by Evan Zeitler
peiferlabunc.bsky.social
With ICE in the Triangle, UNC student and faculty groups are joining to demand that our Campus leadership ensure the safety of its students and staff in the face of domestic terrorism! @unc-ch-aaup.bsky.social + TransparUNCy +SUNRISE UNC
Joint Statement on U.S. Customs and Border Protection Presence at UNC-Chapel Hill We demand that UNC Chapel Hill ensure the safety of its students and staff in the face of domestic terrorism. With the U.S. Customs and Border Protection (CBP) entering the Triangle, issues that seemed distant are now close to home. CBP actions in Chicago, Portland, and Charlotte suggest that they know no limits. In Charlotte this week, among the over 200 abductions under the auspices of legal arrest, they dragged a US citizen out of his car after shattering his car window. Federal agents shattered car windows with the muzzle of a loaded assault rifle. CBP agents entered a church and kidnapped people in front of their children. Earlier this year, CBP agents murdered a person during a traffic stop. These actions mean that many of our UNC community members and families are now living in fear, as simply “looking Latin” can lead to detention. International policing, border control, and other parts of the surveillance apparatus exploit racism and xenophobia to project the lens of risk onto innocent people. Under this kind of state, no one is safe, and we must protect those most vulnerable to harm. Furthermore, we know that CBP targets community members who act to protect each other, arresting people in clear violation of their rights to punish them through the judicial process. Nevertheless, we as members of the UNC community, must speak out and act to protect one another. University leaders must unwaveringly support students, staff, and faculty—yesterday’s tepid statement from Interim Provost Dean is inadequate to meet the moment of fear and uncertainty. Interim Provost Dean reiterated that while CBP can approach individuals in public spaces, they must have a judicial warrant to enter classrooms and residence halls. The extrajudicial killing and kidnapping we have seen by CBP over the last month indicate that they will continue to ignore the law as they have been given a blank check …
November 19, 2025 at 5:48 PM
Reposted by Evan Zeitler
triangleblogblog.bsky.social
We will not report anything without confirmation which we do independently. If you see something, the best place to call is @siembranc.bsky.social’s hotline. Also please follow them.
November 19, 2025 at 1:20 AM
Reposted by Evan Zeitler
kidneyint.bsky.social
REMODELing Mechanistic Trials for Kidney Disease: a multi-modal, tissue-centered approach to understand the renal mechanism of action of #semaglutide

doi.org/10.1016/j.kint.2025.10.005

#OpenAccess #MedSky #NephSky #CKD #diabetes @uwnephrology.bsky.social @umich.edu @kidney-resrch-inst.bsky.social
November 12, 2025 at 6:32 PM
Reposted by Evan Zeitler
nephrosparks.bsky.social
The 2025 #NephMadness logo dropped

#kidneywk

ajkdblog.org/2025/11/06/n...
November 6, 2025 at 2:08 PM
littlebiggloms.bsky.social
If you're not at the #KidneyWk plenary this morning, you are missing @robcaliff.bsky.social absolutely putting people on notice about the real issues we face in US healthcare. Great speech.
November 8, 2025 at 2:20 PM
Reposted by Evan Zeitler
jama.com
Among more than 800 000 CKD-PC participants, discordance between cystatin C and creatinine eGFR values was associated with increased risk of death, cardiovascular events, and kidney failure.

#KidneyWK @asnkidney.bsky.social

ja.ma/4oV4DtU
JAMA graph shows association of eGFR difference with risks of long-term adverse outcomes. Hazard ratio vs. difference between eGFRcys & eGFRcr (%). Lines for death, CVD death, heart failure, ASCVD, KFRT are plotted. Declining risk as difference approaches zero.
November 7, 2025 at 8:15 PM
Reposted by Evan Zeitler
hswapnil.medsky.social
And @brendonneuen.bsky.social with another simultaneous pub in @jama.com

jamanetwork.com/journals/jam...

Flozination by GFR/albuminuria

#KidneyWk
SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria
This meta-analysis examines whether estimated glomerular filtration rate or degree of albuminuria, as measured by urinary albumin to creatinine ratio, modifies the effects of sodium-glucose cotranspor...
jamanetwork.com
November 8, 2025 at 12:05 AM
littlebiggloms.bsky.social
REMODEL is fantastic demonstration of what we can do with collaborative effort to perform what Kathy Tuttle calls mechanistic clinical trials!

Semaglutide provides kidney protection via improvements in inflammation and microvascular function. Lots of data to parse going forward. #KidneyWk
November 7, 2025 at 11:13 PM
Reposted by Evan Zeitler
nejm.org
ORIGIN phase 3 trial: In an interim analysis of a clinical trial, atacicept, a fusion protein that binds and inhibits two cytokines thought to be central to the pathophysiology of IgA nephropathy, significantly reduced proteinuria. nej.md/3JEq8QL

@asnkidney.bsky.social | #KidneyWk
American Society of Nephrology Kidney Week 2025 Original Article | Nov. 6, 2025 | NEJM.org A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy Figure 2A. Change from Baseline in 24-Hr Urinary Protein-to-Creatinine Ratio through Week 36. The NEJM identity sits at the bottom.
November 6, 2025 at 2:55 PM
Reposted by Evan Zeitler
ssfarouk.bsky.social
Application for #NephSIM Nephrons are due 11/13:

A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers

Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘

nephsim.com/nephsim-neph...
November 6, 2025 at 3:05 PM
Reposted by Evan Zeitler
hswapnil.medsky.social
Eli Lilly continuing to hit it out the park

Selective amylin agonist as an alternative to GLP1RAs? #eloralintide

www.thelancet.com/journals/lan... in @thelancet.com

(Yeah I know it’s #KidneyWk but what do we do till Houston wakes up!)

cc @rnflex.bsky.social
Figure 2. Change in bodyweight (A) Mean percent change in bodyweight from baseline to week 48, shown as observed means and bars indicating SEs. The model-based estimates of the mean percent change in bodyweight and differences among treatment groups at week 48 with the corresponding p values (efficacy estimand only) and 95% CIs are shown in (B) (efficacy estimand) and (D) (treatment-regimen estimand); bars indicate SEs. Multiplicity adjustment was not performed, and p values should be interpreted as exploratory. (C) shows the percentage of participants with bodyweight reductions of at least 5%, 10%, 15%, 20%, 25%, and 30% from baseline to week 48. The percentage of participants is annotated above each bar, calculated with the use of Rubin's rules by combining the percentages of participants who met the thresholds in imputed datasets. *The model-based estimates and 95% CIs from a mixed model repeated measures analysis for the efficacy estimand are shown on the right, denoted by 48.
November 6, 2025 at 1:54 PM
littlebiggloms.bsky.social
Is watching Independence Day while I eat take out in my room for preparation for #KidneyWk?

Hell yes it is! Tomorrow, let us celebrate our Independence Day...from kidney diseases!
November 6, 2025 at 2:32 AM
littlebiggloms.bsky.social
It's been real #ObesityWeek! Thanks for letting some nephrons share your space.

Off to HOU for the start of #KidneyWk on my CKM tour!
November 5, 2025 at 8:12 PM
Reposted by Evan Zeitler
kairyssdal.bsky.social
Ummmm…
factpostnews.bsky.social FactPost @factpostnews.bsky.social · 24d
Vance says it is "totally reasonable and acceptable" for people to not want to live next door to people who speak a different language than they do
October 29, 2025 at 4:54 PM
Reposted by Evan Zeitler
joedelong.bsky.social
Powerful sign at No Kings in Cleveland
October 18, 2025 at 7:08 PM
Reposted by Evan Zeitler
alexchangmd.bsky.social
How do you all think ASN kidney week international attendance will be like this year? Just got an email about one of the collaborative groups. I work with having half as many as expected coming… #Tariffslawlessnessandsuch @hswapnil.medsky.social
October 16, 2025 at 7:02 PM
Reposted by Evan Zeitler
hswapnil.medsky.social
The opening plenary at #KidneyWk looks phenomenal

Renal RCT Renaissance is upon us

(LBCT list drops tomorrow)

www.asn-online.org/education/ki...
program for thursday at kidney wk including 2 LBCTs and Vlado P talking on RCTs and curing kidney disease
October 16, 2025 at 1:10 PM
littlebiggloms.bsky.social
Okay, I have been absentee for a while now but I had to come back for this one just to see what @hswapnil.medsky.social would say!

COI: strongly prejudiced against dietary restriction in almost every form

#NephJC
October 15, 2025 at 1:03 AM
Reposted by Evan Zeitler
4nikkolas.bsky.social
after millions of views and shares of my Portland Frog art. (thank you all🙏🏾) I got requests to highlight priests, and chickens, and Chicagoans, and T-Rexes, and more… all of us who refuse to bend the knee. so this is for US.
𝚂𝚝𝚊𝚗𝚍 𝚃𝚊𝚕𝚕.
𝚆𝚎 𝚆𝚒𝚕𝚕 𝚆𝚒𝚗.
October 10, 2025 at 9:11 PM
Reposted by Evan Zeitler
eric-reinhart.com
ICE just blatantly violated the law and arrested sitting Chicago Alderperson Jessie Fuentes while seeking to illegally arrest a patient in a hospital. Fuck these fascists.
October 3, 2025 at 7:19 PM
Reposted by Evan Zeitler
maaloufmd.bsky.social
My husband was detained by ICE today

Juan Muñoz, an American citizen, father of 2, and local government official, was peacefully protesting w. other elected officials. He was assaulted and taken away

I have had zero contact or updates since

#SOS
@duckworth.senate.gov @durbin.senate.gov
October 3, 2025 at 5:12 PM
Reposted by Evan Zeitler
jci.org
ICYMI: How diet affects atherosclerosis in obesity…

@aweinstock.bsky.social & team show short-term caloric restriction resolves atherosclerosis inflammation in obese mice, but weight regain accelerates its adverse effects: buff.ly/ieqwQ3O
September 21, 2025 at 12:04 PM
Reposted by Evan Zeitler
ryanmarino.bsky.social
Casey Means, the influencer who did not complete medical training but is nominated for Surgeon General, has been extremely critical of financial conflicts of interest in medicine. But she has made hundreds of thousands shilling supplements like algae & basil seed, and from investments in big tobacco
September 16, 2025 at 7:58 PM
littlebiggloms.bsky.social
Apropos of nothing in particular, always good to KNOW YOUR RIGHTS.

www.aclusocal.org/en/know-your...
When stopped by an officer
IF YOU ARE STOPPED, QUESTIONED OR SEARCHED BY A LAW ENFORCEMENT OFFICERAn encounter with law enforcement can be stressful and scary. Below we describe your constitutional rights during police
www.aclusocal.org
September 8, 2025 at 5:23 PM
Reposted by Evan Zeitler
physiciandemocracy.medsky.social
In 1900, 31% of all deaths were children under the age of 5. Today it’s 0.7%. Vaccines, medications, and modern science are the reason why. Trust the science, it’s been proven to work safely and efficiently time and time again.
September 4, 2025 at 12:07 AM