Lis Lowe
@lislowe.bsky.social
Scientist, mum, wife. Fan of gut bacteria, mycobacteria, glycans and cazymes. Mannose evangelist. Lowe Lab, NUBI, Newcastle University
Reposted by Lis Lowe
I wrote about my play and where it came from for @qxmagazine.bsky.social :
www.qxmagazine.com/2025/11/i-dr...
www.qxmagazine.com/2025/11/i-dr...
I Dream Of Theresa May: Vivek Nityananda writes about his new play at Tara Theatre, 17 - 29 November 2025
I Dream Of Theresa May: Vivek Nityananda writes about his new play at Tara Theatre, which runs from 17 - 29 November 2025.
www.qxmagazine.com
November 13, 2025 at 3:46 PM
I wrote about my play and where it came from for @qxmagazine.bsky.social :
www.qxmagazine.com/2025/11/i-dr...
www.qxmagazine.com/2025/11/i-dr...
Reposted by Lis Lowe
Pleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....
November 13, 2025 at 9:57 AM
Pleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....
Reposted by Lis Lowe
Funded PhD opportunity for anyone interested in using cutting-edge chemistry to look at glycan profiles in prostate cancer samples 🙌🏻
The successful student will be based at the University of York with Prof Alison Parkin with the opportunity to carry out a placement at the @nucancer.bsky.social
The successful student will be based at the University of York with Prof Alison Parkin with the opportunity to carry out a placement at the @nucancer.bsky.social
MRC DiMeN Doctoral Training Partnership: Rapid and sensitive diagnostic ‘fingerprinting’ of prostate cancer O-glycans using Fourier-Transform alternative current voltammetry (FTACV) at University of Y...
PhD Project - MRC DiMeN Doctoral Training Partnership: Rapid and sensitive diagnostic ‘fingerprinting’ of prostate cancer O-glycans using Fourier-Transform alternative current voltammetry ...
eur03.safelinks.protection.outlook.com
November 11, 2025 at 3:48 PM
Funded PhD opportunity for anyone interested in using cutting-edge chemistry to look at glycan profiles in prostate cancer samples 🙌🏻
The successful student will be based at the University of York with Prof Alison Parkin with the opportunity to carry out a placement at the @nucancer.bsky.social
The successful student will be based at the University of York with Prof Alison Parkin with the opportunity to carry out a placement at the @nucancer.bsky.social
Reposted by Lis Lowe
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 7:48 AM
Excited to share our preprint led by Carlos Voogdt et al
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
Spending some time collecting memories of Harry today 🥺 - this is when he was elected a Fellow of the Royal Society. If anyone in the #glycotime universe has pictures or memories of Harry Gilbert they want to share please send them my way 💚
September 29, 2025 at 11:00 AM
Spending some time collecting memories of Harry today 🥺 - this is when he was elected a Fellow of the Royal Society. If anyone in the #glycotime universe has pictures or memories of Harry Gilbert they want to share please send them my way 💚
Reposted by Lis Lowe
Next up,
Dr Kate Beckham @kshbeckham.bsky.social
The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.
www.ncl.ac.uk/cbcb/staff/p...
Dr Kate Beckham @kshbeckham.bsky.social
The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.
www.ncl.ac.uk/cbcb/staff/p...
September 23, 2025 at 8:53 AM
Next up,
Dr Kate Beckham @kshbeckham.bsky.social
The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.
www.ncl.ac.uk/cbcb/staff/p...
Dr Kate Beckham @kshbeckham.bsky.social
The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.
www.ncl.ac.uk/cbcb/staff/p...
Reposted by Lis Lowe
Day 2 of MHD introductions 😃
Dr Lis Lowe @lislowe.bsky.social
The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.
Dr Lis Lowe @lislowe.bsky.social
The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.
September 23, 2025 at 8:41 AM
Day 2 of MHD introductions 😃
Dr Lis Lowe @lislowe.bsky.social
The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.
Dr Lis Lowe @lislowe.bsky.social
The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.
Reposted by Lis Lowe
Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
Convergent evolution of distinct D-ribulose utilisation pathways in attaching and effacing pathogens - Nature Communications
Cottam et al. identify distinct pathways for D-ribulose utilisation in pathogenic Escherichia coli and Citrobacter rodentium, providing mechanistic details and suggesting convergent evolution towards ...
www.nature.com
July 30, 2025 at 9:24 AM
Absolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
Reposted by Lis Lowe
*JOB AD*: interested in doing a postdoc in microbial metabolomics? Passionate about natural products mass spec?
Come join the group! Informal enquires welcome!
Closing Date: 19 August 2025
jobs.ncl.ac.uk/job/Newcastl...
Come join the group! Informal enquires welcome!
Closing Date: 19 August 2025
jobs.ncl.ac.uk/job/Newcastl...
Research Associate - Microbial Metabolomic
Research Associate - Microbial Metabolomic
jobs.ncl.ac.uk
July 22, 2025 at 2:32 PM
*JOB AD*: interested in doing a postdoc in microbial metabolomics? Passionate about natural products mass spec?
Come join the group! Informal enquires welcome!
Closing Date: 19 August 2025
jobs.ncl.ac.uk/job/Newcastl...
Come join the group! Informal enquires welcome!
Closing Date: 19 August 2025
jobs.ncl.ac.uk/job/Newcastl...
On the way home from a really great CAZyme GRC. Lots of v interesting talks, a poster prize for Jean-Lou, karaoke, lake swims, beers, catching up with friends, and a lot of responsibility in 2029 when I co-Chair the meeting!
July 25, 2025 at 8:41 PM
On the way home from a really great CAZyme GRC. Lots of v interesting talks, a poster prize for Jean-Lou, karaoke, lake swims, beers, catching up with friends, and a lot of responsibility in 2029 when I co-Chair the meeting!
Reposted by Lis Lowe
Farewell drinks with this guy. @wragbags.bsky.social we will miss you
July 16, 2025 at 3:25 PM
Farewell drinks with this guy. @wragbags.bsky.social we will miss you
Reposted by Lis Lowe
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco
July 7, 2025 at 8:21 AM
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco
Reposted by Lis Lowe
Learning from bacterial predators on porin-like proteins that trap lipids at rdcu.be/euXWk! Amazing insights by Rebecca J. Parr & Andrew L. Lovering @unibirmingham.bsky.social, and @lalouxlab.bsky.social, as well as all collaborators including Liz Sockett. #MicroSky #predatoryBacteria #porins
A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily
Nature Communications - This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows...
rdcu.be
July 7, 2025 at 8:29 AM
Learning from bacterial predators on porin-like proteins that trap lipids at rdcu.be/euXWk! Amazing insights by Rebecca J. Parr & Andrew L. Lovering @unibirmingham.bsky.social, and @lalouxlab.bsky.social, as well as all collaborators including Liz Sockett. #MicroSky #predatoryBacteria #porins
Reposted by Lis Lowe
Anyway this trans kids book is less than a quid on a place that is definitely not a library but 🤷😑
Idk how long this particular 99p offer is on for so I suggest everyone RUN to grab a Jamie ebook right now: www.amazon.co.uk/gp/aw/d/B0B1...
July 4, 2025 at 8:35 AM
Anyway this trans kids book is less than a quid on a place that is definitely not a library but 🤷😑
Reposted by Lis Lowe
🦠 NEW VIDEO 🦠
The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well.
Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology
The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well.
Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology
July 2, 2025 at 6:38 PM
🦠 NEW VIDEO 🦠
The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well.
Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology
The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well.
Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology
Reposted by Lis Lowe
In about a week we (Biological Sciences @ Monash Uni in Melbourne, Australia) will be opening a search for 3 (!!!) permanent academic positions (40% research, 40% teaching, 20% service) at Lecturer/Senior Lecturer. 1 Genomics, 2 Ecology. Please share, email me, DM, follow, send carrier pigeons…
June 24, 2025 at 12:27 PM
In about a week we (Biological Sciences @ Monash Uni in Melbourne, Australia) will be opening a search for 3 (!!!) permanent academic positions (40% research, 40% teaching, 20% service) at Lecturer/Senior Lecturer. 1 Genomics, 2 Ecology. Please share, email me, DM, follow, send carrier pigeons…
Reposted by Lis Lowe
Jinich et al. present an important new resource for the Mtb community!
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens.
#MicroSky #Mycobacterium #tuberculosis
onlinelibrary.wiley.com/doi/10.1111/...
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens.
#MicroSky #Mycobacterium #tuberculosis
onlinelibrary.wiley.com/doi/10.1111/...
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large‐Scale Guide to Genetic Conditional Essentiality
Mtb transposon sequencing database is a unified resource for exploring conditional gene essentiality in Mycobacterium tuberculosis. By standardizing over 150 transposon sequencing screens, it enables...
onlinelibrary.wiley.com
June 24, 2025 at 11:27 AM
Jinich et al. present an important new resource for the Mtb community!
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens.
#MicroSky #Mycobacterium #tuberculosis
onlinelibrary.wiley.com/doi/10.1111/...
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens.
#MicroSky #Mycobacterium #tuberculosis
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Lis Lowe
#profile update - last full week as an employee at an established certain “Higher Education” institution. Then I just get a vacation until the end of July #itsbeenablast
June 23, 2025 at 5:09 AM
#profile update - last full week as an employee at an established certain “Higher Education” institution. Then I just get a vacation until the end of July #itsbeenablast
Reposted by Lis Lowe
GenerationResearch has two fully funded MRes positions (including stipend!) for UK Home students for projects in Chemistry (including structural biology). Applications are due June 19th, and students from underrepresented backgrounds are encouraged to apply. Please share!
Two funded Chemistry Masters by Research studentships
We want to recruit two enthusiastic and motivated graduates into our multidisciplinary scientific team to develop new data analysis pipelines to monitor obesity in a mouse disease model. Obesity is a ...
generationresearch.ac.uk
June 13, 2025 at 8:32 AM
GenerationResearch has two fully funded MRes positions (including stipend!) for UK Home students for projects in Chemistry (including structural biology). Applications are due June 19th, and students from underrepresented backgrounds are encouraged to apply. Please share!
Reposted by Lis Lowe
Highly recommend these constructive ‘pitch your grant idea’ sessions open to all. A good way for everyone to hear new ideas and how to develop those aims. Always helped along by a supply of cake!
Yesterday was another round of Pitch to Peers within the Microbes in Health and Disease theme (MHD #dreamtheme), a great insight into the grant writing process and writers across the full career spectrum (ECR - established academics).
June 12, 2025 at 6:36 AM
Highly recommend these constructive ‘pitch your grant idea’ sessions open to all. A good way for everyone to hear new ideas and how to develop those aims. Always helped along by a supply of cake!
Reposted by Lis Lowe
Too cool to be true? 😎 Nope! GlycoShape ReGlyco runs on PyMol through the GlycoMe interface 🥰😍 check out this fab #glycotime tool from Hiren @glyco.me and Ojas @ojas-singh.bsky.social ⤵️🥳🥳🥳🎉🎉
Well, it turns out that you can actually make PyMOL do quite a lot of stuff. Here's the full workflow, integrating the amazing ReGlyco into PyMOL to re-glycosylate the LDLA linker. There's some serious magic needed to get it running as fast as it is within PyMOL. @elisafadda.bsky.social
June 11, 2025 at 6:33 AM
Too cool to be true? 😎 Nope! GlycoShape ReGlyco runs on PyMol through the GlycoMe interface 🥰😍 check out this fab #glycotime tool from Hiren @glyco.me and Ojas @ojas-singh.bsky.social ⤵️🥳🥳🥳🎉🎉
Holy forking shirtballs this Giro has been 🔥🔥🔥
May 31, 2025 at 3:47 PM
Holy forking shirtballs this Giro has been 🔥🔥🔥
Reposted by Lis Lowe
“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”
Is the UK paying the price for world’s most expensive visas? | The Observer
Competing political and economic goals on immigration are resulting in the loss of valuable skills and talent in the UK
observer.co.uk
May 12, 2025 at 10:03 AM
“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”
Reposted by Lis Lowe
Why are prior and concurrent #TB such huge risk factors for M. abscessus infection? #zebrafish preprint lead by our research officer Denise Wee discovers tuberculous granulomas (yellow blob) act as a safe haven for opportunistic mycobacterial pathogens (magenta blobs).
May 9, 2025 at 1:59 AM
Why are prior and concurrent #TB such huge risk factors for M. abscessus infection? #zebrafish preprint lead by our research officer Denise Wee discovers tuberculous granulomas (yellow blob) act as a safe haven for opportunistic mycobacterial pathogens (magenta blobs).
Reposted by Lis Lowe
Postdoc position available!
This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠
Please re-post 🙏
www.jobs.ac.uk/job/DMY885/r...
This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠
Please re-post 🙏
www.jobs.ac.uk/job/DMY885/r...
Research Assistant/Associate - Mapping the Bacterial Cell Wall with Super-resolution Microscopy at Newcastle University
Apply for the Research Assistant/Associate - Mapping the Bacterial Cell Wall with Super-resolution Microscopy role on jobs.ac.uk, the top job board for academic positions in higher education. View det...
www.jobs.ac.uk
May 6, 2025 at 12:43 PM
Postdoc position available!
This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠
Please re-post 🙏
www.jobs.ac.uk/job/DMY885/r...
This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠
Please re-post 🙏
www.jobs.ac.uk/job/DMY885/r...