Typas Lab
banner
typaslab.bsky.social
Typas Lab
@typaslab.bsky.social
Systems Microbiology @EMBL, combining high-throughput approaches & mechanism in bacteria, antibiotics, microbiome, infection, species diversity, cell envelope

https://www.embl.org/groups/typas/
Pinned
Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
Reposted by Typas Lab
Excited to announce my upcoming @snsf.ch Ambizione research group at EPFL on bacteria-host interactions, combining systems approaches and microphysiological models.
🚨 We have an open PhD position! More info on projects and how to apply here: elisabettacacace.github.io/BHI-Lab/
🧪
February 6, 2026 at 3:50 PM
Reposted by Typas Lab
It has been two weeks since the unexpected death of Peer Bork, and all of us in his research group are deeply missing him. His scientific vision brought us together as a team, and we are immensely grateful for the time we spent together. 🧵
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...
January 30, 2026 at 3:05 PM
Reposted by Typas Lab
➡️ Prof. Dr. Dmitri Petrov from the School of Humanities and Science | Department of Biology, Stanford University, spoke today at the @leibnizfli.bsky.social about “Barcoding Fitness Landscapes of Tumorigenesis”. Before he gave his lecture, we had the opportunity to interview him.

🎤 bit.ly/4r66mxG
Interview with Prof. Dr. Dmitri Petrov
YouTube video by Leibniz-Institut für Alternsforschung - FLI e.V.
youtu.be
January 22, 2026 at 2:54 PM
Reposted by Typas Lab
📢 Prof. Dr. Dmitri Petrov from the School of Humanities and Science | Department of Biology, Stanford University, will give a lecture on “Barcoding Fitness Landscapes of Tumorigenesis” at the @leibnizfli.bsky.social on January 22, 2026.

👉 More information: bit.ly/4pGtqSu
January 16, 2026 at 9:40 AM
Reposted by Typas Lab
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...
January 22, 2026 at 7:40 AM
Reposted by Typas Lab
We mourn the passing of Peer Bork, EMBO Member since 2000: https://www.embl.org/news/embl-announcements/in-remembrance-of-peer-bork/
In remembrance of Peer Bork  | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General. 
www.embl.org
January 17, 2026 at 2:52 AM
Reposted by Typas Lab
20 | Peer Bork and the scientific candy shop
Apple: podcasts.apple.com/us/podcast/n...
Spotify: open.spotify.com/episode/17ux...
20 | Peer Bork and the scientific candy shop
Podcast Episode · Night Science · 09/02/2022 · 29m
podcasts.apple.com
January 18, 2026 at 12:52 AM
Reposted by Typas Lab
Peer Bork died yesterday 💔 which shocked me. In 2003 I did a short-term fellowship in Peer’s lab because I idolized him. I met Martin there & we wrote this paper together. Peer was great at bringing people together; a master collaborator with a rare ability to think up big ideas.
January 18, 2026 at 12:52 AM
Reposted by Typas Lab
This is such hard news to process. Such an amazing scientist and inspiration for so many of us.
www.embl.org/news/embl-an...
In remembrance of Peer Bork  | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 16, 2026 at 6:01 PM
Reposted by Typas Lab
Super excited to share our new selection-free CRISPR-Cas9 editing protocol for Dictyostelids, generating 80% KO and 30% KI efficiencies without selection in D. discoideum, and being effective in Dictyostelid species that diverged millions of years ago! www.biorxiv.org/content/10.1...
March 25, 2025 at 8:34 PM
Reposted by Typas Lab
HT-PELSA, a new proteomics tool by EMBL researchers, processes samples 100x faster and works directly with complex crude cell, tissue, and bacterial lysates – developments which could accelerate drug discovery and basic biological research 💊

🔗 www.embl.org/news/science...
November 5, 2025 at 10:09 AM
Reposted by Typas Lab
Happy to see our HT-PELSA paper now published in @natsmb.nature.com 🎊 Big thanks for the constructive review process! 📖Read the manuscript here (www.nature.com/articles/s41...) & check the thread for additional information ⬇️
November 5, 2025 at 10:15 AM
Reposted by Typas Lab
Very excited to share the latest work from our lab, which was published today in Nature!
nature.com/articles/s41...

PhD graduate and now post-doc Sofia Dahlman, along with co-senior author Sam Forster from The Hudson and other researchers from our lab and others.
Isolation, engineering and ecology of temperate phages from the human gut - Nature
Human host-associated cellular products may act as induction agents for bacteriophages.
nature.com
October 15, 2025 at 9:41 PM
Reposted by Typas Lab
#Perspective

Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.

#MicroSky #MicrobiomeSky 🦠

www.nature.com/articles/s41...
How nutrient starvation impacts the gut microbiome - Nature Microbiology
In this Perspective, Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps.
www.nature.com
October 1, 2025 at 5:56 PM
Reposted by Typas Lab
Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...
Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology
Structural and functional characterization of the β-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable β-barrel–surface lipoprotein complex assembly.
doi.org
October 2, 2025 at 6:20 AM
Reposted by Typas Lab
Looking to start your own lab? 🧬🧪 The Helmholtz Institute Würzburg (HIRI) is offering group leader positions in RNA biology, RNA medicine & RNA technology. Apply by October 31 at www.helmholtz-hiri.de/en/jobs-tale...
E15 Groups
The Helmholtz Institute for RNA-based Infection Researchopens a call for
www.helmholtz-hiri.de
October 13, 2025 at 1:30 PM
Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 7:48 AM
Reposted by Typas Lab
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
October 8, 2025 at 9:45 PM
Reposted by Typas Lab
Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.

Until now, using AccuSNV.

Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV
Accurate detection of mutations within bacterial species is critical for fundamental studies of microbial evolution, reconstructing transmission events, and identifying antimicrobial resistance mutati...
www.biorxiv.org
September 29, 2025 at 7:45 PM
Reposted by Typas Lab
📣The 2026 ERC Consolidator Grant competition is now open! 📣

Already preparing your proposal? Info links ⬇️

Info for applicants 👉 buff.ly/PSbeUxX

Application portal 👉 buff.ly/mauZoqo

Deadline: 13/01/26

General info on #ERCCoG 👉 buff.ly/KCN6GTh
September 26, 2025 at 2:30 PM
Reposted by Typas Lab
🏆 Fighting the Gender Award Gap: Microbiologist Prof Dr Lisa Maier from @unituebingen.bsky.social received the main award of the German Association for #Microbiology and Hygiene at the #DGHM meeting in Jena. Congratulations to @lisamaierlab.bsky.social we are proud of you! 💜
📸 Gabriele Pradel
September 23, 2025 at 8:39 AM
Reposted by Typas Lab
Open Call for Expressions of Interest: become a Max Planck Director & redefine what’s possible in science! We offer scientific independence, long-term stable funding & exceptional infrastructure. Lead your own department & open new frontiers of research. Apply by 31 Oct 2025 → www.mpg.de/directors
Directors
The Max Planck Society offers Directors a unique platform for groundbreaking research and leadership in diverse scientific fields.
www.mpg.de
September 17, 2025 at 3:25 PM
Reposted by Typas Lab
Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...
September 15, 2025 at 9:27 AM
Reposted by Typas Lab
Join EMBL AI!

We have ambitious plans to transform life sciences research through AI.

Interested in using ML/AI to solve complex interdisciplinary challenges?

We’re looking for two senior leaders based at EMBL Heidelberg👇
September 11, 2025 at 7:24 AM
Reposted by Typas Lab
New academic faculty posts available at Imperial College London! Assistant/Associate Professors in Life Sciences. Please apply and/or circulate details!

www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
August 18, 2025 at 8:25 AM