Jon Marles-Wright
@jmarlesw.bsky.social
Scientist, husband to @lislowe, father. Views my own. He/him.
Reposted by Jon Marles-Wright
www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com
PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com
www.findaphd.com
January 23, 2026 at 10:33 AM
www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
Reposted by Jon Marles-Wright
BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
www.findaphd.com
January 23, 2026 at 12:34 PM
BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info
Exciting CASE funded PhD opportunity available in the NEEDL PhD programme with me and Thomas Howard: eur03.safelinks.protection.outlook.com?url=https%3A...
Synthetic Biology for Light-Activated Smart Materials. at Newcastle University on FindAPhD.com
PhD Project - Synthetic Biology for Light-Activated Smart Materials. at Newcastle University, listed on FindAPhD.com
eur03.safelinks.protection.outlook.com
January 23, 2026 at 10:11 AM
Exciting CASE funded PhD opportunity available in the NEEDL PhD programme with me and Thomas Howard: eur03.safelinks.protection.outlook.com?url=https%3A...
Reposted by Jon Marles-Wright
We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT
January 18, 2026 at 2:30 PM
We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT
Reposted by Jon Marles-Wright
🚨Last chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...
www.findaphd.com
January 6, 2026 at 3:56 PM
🚨Last chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...
Reposted by Jon Marles-Wright
Reposted by Jon Marles-Wright
Please RT. Post-doc opportunity alert! 💥 closing soon 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
December 5, 2025 at 5:06 PM
Please RT. Post-doc opportunity alert! 💥 closing soon 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
Reposted by Jon Marles-Wright
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
November 18, 2025 at 10:18 AM
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
Reposted by Jon Marles-Wright
Proud and excited to see my first, first-author paper out on @pnas.org! Huge thank you to Jon @jmarlesw.bsky.social, Luning and my colleagues for their amazing guidance throughout.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
November 14, 2025 at 1:22 PM
Proud and excited to see my first, first-author paper out on @pnas.org! Huge thank you to Jon @jmarlesw.bsky.social, Luning and my colleagues for their amazing guidance throughout.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Jon Marles-Wright
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology
Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...
www.nature.com
November 13, 2025 at 8:14 PM
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Pleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....
November 13, 2025 at 9:57 AM
Pleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....
Reposted by Jon Marles-Wright
I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Structural insights into cobalamin loading and reactivation of human methionine synthase
Human methionine synthase (MTR) is an essential enzyme of one carbon metabolism. Consisting of a catalytic N-half and a cobalamin binding C-half, MTR utilises this intricate organometallic cofactor in...
www.biorxiv.org
November 11, 2025 at 12:48 PM
I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Reposted by Jon Marles-Wright
Afternoon starts with former #Salgadolab student @adamcrawshaw.bsky.social getting the audience engaged on #microcrystals and @diamondlightsource.bsky.social VMXm beamline.
November 6, 2025 at 1:52 PM
Afternoon starts with former #Salgadolab student @adamcrawshaw.bsky.social getting the audience engaged on #microcrystals and @diamondlightsource.bsky.social VMXm beamline.
Reposted by Jon Marles-Wright
Another exciting day in Newcastle for structural biology! The CCP4 Structural Biology Meeting 2025 is here!
November 6, 2025 at 10:27 AM
Another exciting day in Newcastle for structural biology! The CCP4 Structural Biology Meeting 2025 is here!
Reposted by Jon Marles-Wright
A great overview of #cryoEM in Newcastle from @jmarlesw.bsky.social at #NorthernEye opening @nusbf.bsky.social
November 5, 2025 at 10:31 AM
A great overview of #cryoEM in Newcastle from @jmarlesw.bsky.social at #NorthernEye opening @nusbf.bsky.social
Reposted by Jon Marles-Wright
Woo. The big day is finally here. @jmarlesw.bsky.social kicking off the Northern Eye Opening Symposium
November 5, 2025 at 10:28 AM
Woo. The big day is finally here. @jmarlesw.bsky.social kicking off the Northern Eye Opening Symposium
Reposted by Jon Marles-Wright
Please join us in the North East on the 5th of November as we celebrate with a one day symposium for the launch of our BBSRC funded 100 keV Tundra TEM aka the Northern Eye:
nusbf.ncl.ac.uk/ccpem-tfs-ne...
The symposium has been kindly sponsored by
@thermofishersci.bsky.social & @ccpem.bsky.social
nusbf.ncl.ac.uk/ccpem-tfs-ne...
The symposium has been kindly sponsored by
@thermofishersci.bsky.social & @ccpem.bsky.social
Grand Opening of the Northern eye, a cryo-TEM in Newcastle
Grand Opening of the Northern Eye in Newcastle, a100 kV Tundra cryo-TEM in Newcastle University on Wednesday 5th November 2025
nusbf.ncl.ac.uk
October 21, 2025 at 9:31 AM
Please join us in the North East on the 5th of November as we celebrate with a one day symposium for the launch of our BBSRC funded 100 keV Tundra TEM aka the Northern Eye:
nusbf.ncl.ac.uk/ccpem-tfs-ne...
The symposium has been kindly sponsored by
@thermofishersci.bsky.social & @ccpem.bsky.social
nusbf.ncl.ac.uk/ccpem-tfs-ne...
The symposium has been kindly sponsored by
@thermofishersci.bsky.social & @ccpem.bsky.social
Interested in alpha-oxoamine synthases and their use in biotech? Here's a nice methods paper on the production and characterisation of an engineered T. maritima variant from colleagues in the @campopianogroup.bsky.social: www.sciencedirect.com/science/arti...
Characterisation and engineering of thermostable PLP-dependent alpha-oxoamine synthases (AOSs); versatile C-C bond forming biocatalysts
The toolbox of C-C bond forming biocatalysts is forever expanding as demand increases for new and sustainable routes to organic molecules. One class o…
www.sciencedirect.com
September 29, 2025 at 8:54 AM
Interested in alpha-oxoamine synthases and their use in biotech? Here's a nice methods paper on the production and characterisation of an engineered T. maritima variant from colleagues in the @campopianogroup.bsky.social: www.sciencedirect.com/science/arti...
Reposted by Jon Marles-Wright
The Quinn group are interested in stress-sensing and signalling mechanisms in human pathogenic fungi and their importance in virulence. They are also interested anti-fungal mechanisms mediated by the bacterial type-vi secretion system.
👉 @nclfungalgroup.bsky.social
www.ncl.ac.uk/medical-scie...
👉 @nclfungalgroup.bsky.social
www.ncl.ac.uk/medical-scie...
September 22, 2025 at 11:39 AM
The Quinn group are interested in stress-sensing and signalling mechanisms in human pathogenic fungi and their importance in virulence. They are also interested anti-fungal mechanisms mediated by the bacterial type-vi secretion system.
👉 @nclfungalgroup.bsky.social
www.ncl.ac.uk/medical-scie...
👉 @nclfungalgroup.bsky.social
www.ncl.ac.uk/medical-scie...
Reposted by Jon Marles-Wright
The Palmer group are interested in the mechanisms bacteria use to compete with one another during colonisation. Her group are focused on the type vii secretion system and the toxins it exports.
Follow @proftracypalmer.bsky.social for more insights.
www.ncl.ac.uk/medical-scie...
Follow @proftracypalmer.bsky.social for more insights.
www.ncl.ac.uk/medical-scie...
September 22, 2025 at 11:38 AM
The Palmer group are interested in the mechanisms bacteria use to compete with one another during colonisation. Her group are focused on the type vii secretion system and the toxins it exports.
Follow @proftracypalmer.bsky.social for more insights.
www.ncl.ac.uk/medical-scie...
Follow @proftracypalmer.bsky.social for more insights.
www.ncl.ac.uk/medical-scie...
Reposted by Jon Marles-Wright
Next up, @nickj-dent-res.bsky.social
His group is interested in all aspects of oral biofilms and how they contribute to oral health and disease. They look at adhesion and colonisation of surfaces, intermicrobial interactions and the role of the biofilm matrix.
blogs.ncl.ac.uk/nickjakubovi...
His group is interested in all aspects of oral biofilms and how they contribute to oral health and disease. They look at adhesion and colonisation of surfaces, intermicrobial interactions and the role of the biofilm matrix.
blogs.ncl.ac.uk/nickjakubovi...
September 22, 2025 at 11:52 AM
Next up, @nickj-dent-res.bsky.social
His group is interested in all aspects of oral biofilms and how they contribute to oral health and disease. They look at adhesion and colonisation of surfaces, intermicrobial interactions and the role of the biofilm matrix.
blogs.ncl.ac.uk/nickjakubovi...
His group is interested in all aspects of oral biofilms and how they contribute to oral health and disease. They look at adhesion and colonisation of surfaces, intermicrobial interactions and the role of the biofilm matrix.
blogs.ncl.ac.uk/nickjakubovi...
Reposted by Jon Marles-Wright
Next introducing Dr Alessandra Dantas.
The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.
@alesdantas.bsky.social
www.ncl.ac.uk/dental/about...
The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.
@alesdantas.bsky.social
www.ncl.ac.uk/dental/about...
September 22, 2025 at 12:32 PM
Next introducing Dr Alessandra Dantas.
The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.
@alesdantas.bsky.social
www.ncl.ac.uk/dental/about...
The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.
@alesdantas.bsky.social
www.ncl.ac.uk/dental/about...
Reposted by Jon Marles-Wright
Last introduction for the today..
Dr Kesha Josts @kjosts.bsky.social
The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.
www.ncl.ac.uk/cbcb/staff/p...
Dr Kesha Josts @kjosts.bsky.social
The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.
www.ncl.ac.uk/cbcb/staff/p...
September 22, 2025 at 12:46 PM
Last introduction for the today..
Dr Kesha Josts @kjosts.bsky.social
The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.
www.ncl.ac.uk/cbcb/staff/p...
Dr Kesha Josts @kjosts.bsky.social
The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.
www.ncl.ac.uk/cbcb/staff/p...
Reposted by Jon Marles-Wright
@jmarlesw.bsky.social is a structural biochemist. His group are interested in how bacteria sense and respond to their environment. Jon is Academic Lead for our Electron Microscopy Facility and is excited for our new Tundra microscope to be up and running.
www.marles-wright-lab.org
www.marles-wright-lab.org
September 22, 2025 at 12:10 PM
@jmarlesw.bsky.social is a structural biochemist. His group are interested in how bacteria sense and respond to their environment. Jon is Academic Lead for our Electron Microscopy Facility and is excited for our new Tundra microscope to be up and running.
www.marles-wright-lab.org
www.marles-wright-lab.org
Welcome week at the university again. Number 28 for me. Looking forward to welcoming our 7th MRes Biotech and Biodesign cohort this morning.
September 15, 2025 at 8:39 AM
Welcome week at the university again. Number 28 for me. Looking forward to welcoming our 7th MRes Biotech and Biodesign cohort this morning.