KJ
@kjgoh.bsky.social
PhD | Biology enthusiast | RF in @LithgowLab at Monash | Video games addict |🏸🏀 lover |
Reposted by KJ
Congratulations to Prof. Adelle Coster, UNSW, to whom I was honoured to present the 2025 Australian Society for Biophysics (ASB) Bob Roberston medal during ASB2025 at @griffith.edu.au. Adelle is pictured with ASB President, @lisannes.bsky.social; inaugural awardee Hans Coster; & myself 2009 medal.
November 23, 2025 at 10:42 AM
Congratulations to Prof. Adelle Coster, UNSW, to whom I was honoured to present the 2025 Australian Society for Biophysics (ASB) Bob Roberston medal during ASB2025 at @griffith.edu.au. Adelle is pictured with ASB President, @lisannes.bsky.social; inaugural awardee Hans Coster; & myself 2009 medal.
Reposted by KJ
Our new paper is out in @natcomms.nature.com! We uncover how the Salmonella SPI-1 injectisome reshapes macrophage translation, resulting in a sustained decrease in inflammatory gene expression. Grateful to all my co-authors and collaborators for an incredible team effort!
The Salmonella pathogenicity island 1 injectisome reprograms host cell translation to evade the inflammatory response - Nature Communications
In this work, authors show that Salmonella uses its SPI-1 injectisome to infect macrophages, triggering rapid translational upregulation of transcription factors, such as EGR1 which suppresses the inf...
www.nature.com
November 6, 2025 at 11:18 AM
Our new paper is out in @natcomms.nature.com! We uncover how the Salmonella SPI-1 injectisome reshapes macrophage translation, resulting in a sustained decrease in inflammatory gene expression. Grateful to all my co-authors and collaborators for an incredible team effort!
Reposted by KJ
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Pressure to publish is rising as research time shrinks, finds survey of scientists
Researchers feel that pressures to publish are increasing, but the time and resources available to do research are decreasing, according to a survey by Elsevier.
go.nature.com
November 7, 2025 at 12:33 PM
Scientists feel that the pressure to publish is rising, but that the time and resources they have to do the necessary research are falling, according to a survey of 3,200 researchers
go.nature.com/4hNDvuN
go.nature.com/4hNDvuN
Reposted by KJ
An Archaea bacterium with an internal membrane system! Amazing and beautiful work!
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 8, 2025 at 12:47 AM
An Archaea bacterium with an internal membrane system! Amazing and beautiful work!
Reposted by KJ
great idea to collaborate with courtney ellison for "...fancy microscopy to capture pilus dynamics!" 👏
October 13, 2025 at 9:33 PM
great idea to collaborate with courtney ellison for "...fancy microscopy to capture pilus dynamics!" 👏
Reposted by KJ
📢 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚂𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝙲𝚕𝚘𝚜𝚒𝚗𝚐 𝚂𝚘𝚘𝚗!!
𝙳𝚘𝚗’𝚝 𝚖𝚒𝚜𝚜 𝚢𝚘𝚞𝚛 𝚌𝚑𝚊𝚗𝚌𝚎 𝚝𝚘 𝚜𝚑𝚊𝚛𝚎 𝚢𝚘𝚞𝚛 𝚛𝚎𝚜𝚎𝚊𝚛𝚌𝚑 𝚊𝚝 𝚝𝚑𝚎 𝙻𝚘𝚛𝚗𝚎 𝙿𝚛𝚘𝚝𝚎𝚒𝚗 𝙲𝚘𝚗𝚏𝚎𝚛𝚎𝚗𝚌𝚎 𝟸𝟶𝟸𝟼. 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚜𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝚌𝚕𝚘𝚜𝚎 𝟸𝟺𝚝𝚑 𝙾𝚌𝚝𝚘𝚋𝚎𝚛 – 𝚜𝚑𝚘𝚠𝚌𝚊𝚜𝚎 𝚢𝚘𝚞𝚛 𝚠𝚘𝚛𝚔 𝚝𝚘 𝚝𝚑𝚎 𝚐𝚕𝚘𝚋𝚊𝚕 𝚙𝚛𝚘𝚝𝚎𝚒𝚗 𝚜𝚌𝚒𝚎𝚗𝚌𝚎 𝚌𝚘𝚖𝚖𝚞𝚗𝚒𝚝𝚢 𝚒𝚗 𝚐𝚕𝚘𝚛𝚒𝚘𝚞𝚜 𝙻𝚘𝚛𝚗𝚎! 🏖️ 🏄♀️ 🏊
👉 𝚂𝚞𝚋𝚖𝚒𝚝:
www.lorneproteins.org/submissions
𝙳𝚘𝚗’𝚝 𝚖𝚒𝚜𝚜 𝚢𝚘𝚞𝚛 𝚌𝚑𝚊𝚗𝚌𝚎 𝚝𝚘 𝚜𝚑𝚊𝚛𝚎 𝚢𝚘𝚞𝚛 𝚛𝚎𝚜𝚎𝚊𝚛𝚌𝚑 𝚊𝚝 𝚝𝚑𝚎 𝙻𝚘𝚛𝚗𝚎 𝙿𝚛𝚘𝚝𝚎𝚒𝚗 𝙲𝚘𝚗𝚏𝚎𝚛𝚎𝚗𝚌𝚎 𝟸𝟶𝟸𝟼. 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚜𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝚌𝚕𝚘𝚜𝚎 𝟸𝟺𝚝𝚑 𝙾𝚌𝚝𝚘𝚋𝚎𝚛 – 𝚜𝚑𝚘𝚠𝚌𝚊𝚜𝚎 𝚢𝚘𝚞𝚛 𝚠𝚘𝚛𝚔 𝚝𝚘 𝚝𝚑𝚎 𝚐𝚕𝚘𝚋𝚊𝚕 𝚙𝚛𝚘𝚝𝚎𝚒𝚗 𝚜𝚌𝚒𝚎𝚗𝚌𝚎 𝚌𝚘𝚖𝚖𝚞𝚗𝚒𝚝𝚢 𝚒𝚗 𝚐𝚕𝚘𝚛𝚒𝚘𝚞𝚜 𝙻𝚘𝚛𝚗𝚎! 🏖️ 🏄♀️ 🏊
👉 𝚂𝚞𝚋𝚖𝚒𝚝:
www.lorneproteins.org/submissions
September 25, 2025 at 3:22 AM
📢 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚂𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝙲𝚕𝚘𝚜𝚒𝚗𝚐 𝚂𝚘𝚘𝚗!!
𝙳𝚘𝚗’𝚝 𝚖𝚒𝚜𝚜 𝚢𝚘𝚞𝚛 𝚌𝚑𝚊𝚗𝚌𝚎 𝚝𝚘 𝚜𝚑𝚊𝚛𝚎 𝚢𝚘𝚞𝚛 𝚛𝚎𝚜𝚎𝚊𝚛𝚌𝚑 𝚊𝚝 𝚝𝚑𝚎 𝙻𝚘𝚛𝚗𝚎 𝙿𝚛𝚘𝚝𝚎𝚒𝚗 𝙲𝚘𝚗𝚏𝚎𝚛𝚎𝚗𝚌𝚎 𝟸𝟶𝟸𝟼. 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚜𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝚌𝚕𝚘𝚜𝚎 𝟸𝟺𝚝𝚑 𝙾𝚌𝚝𝚘𝚋𝚎𝚛 – 𝚜𝚑𝚘𝚠𝚌𝚊𝚜𝚎 𝚢𝚘𝚞𝚛 𝚠𝚘𝚛𝚔 𝚝𝚘 𝚝𝚑𝚎 𝚐𝚕𝚘𝚋𝚊𝚕 𝚙𝚛𝚘𝚝𝚎𝚒𝚗 𝚜𝚌𝚒𝚎𝚗𝚌𝚎 𝚌𝚘𝚖𝚖𝚞𝚗𝚒𝚝𝚢 𝚒𝚗 𝚐𝚕𝚘𝚛𝚒𝚘𝚞𝚜 𝙻𝚘𝚛𝚗𝚎! 🏖️ 🏄♀️ 🏊
👉 𝚂𝚞𝚋𝚖𝚒𝚝:
www.lorneproteins.org/submissions
𝙳𝚘𝚗’𝚝 𝚖𝚒𝚜𝚜 𝚢𝚘𝚞𝚛 𝚌𝚑𝚊𝚗𝚌𝚎 𝚝𝚘 𝚜𝚑𝚊𝚛𝚎 𝚢𝚘𝚞𝚛 𝚛𝚎𝚜𝚎𝚊𝚛𝚌𝚑 𝚊𝚝 𝚝𝚑𝚎 𝙻𝚘𝚛𝚗𝚎 𝙿𝚛𝚘𝚝𝚎𝚒𝚗 𝙲𝚘𝚗𝚏𝚎𝚛𝚎𝚗𝚌𝚎 𝟸𝟶𝟸𝟼. 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚜𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝚌𝚕𝚘𝚜𝚎 𝟸𝟺𝚝𝚑 𝙾𝚌𝚝𝚘𝚋𝚎𝚛 – 𝚜𝚑𝚘𝚠𝚌𝚊𝚜𝚎 𝚢𝚘𝚞𝚛 𝚠𝚘𝚛𝚔 𝚝𝚘 𝚝𝚑𝚎 𝚐𝚕𝚘𝚋𝚊𝚕 𝚙𝚛𝚘𝚝𝚎𝚒𝚗 𝚜𝚌𝚒𝚎𝚗𝚌𝚎 𝚌𝚘𝚖𝚖𝚞𝚗𝚒𝚝𝚢 𝚒𝚗 𝚐𝚕𝚘𝚛𝚒𝚘𝚞𝚜 𝙻𝚘𝚛𝚗𝚎! 🏖️ 🏄♀️ 🏊
👉 𝚂𝚞𝚋𝚖𝚒𝚝:
www.lorneproteins.org/submissions
Reposted by KJ
Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
buff.ly/pZZfIso
buff.ly/pZZfIso
October 1, 2025 at 10:28 PM
Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
buff.ly/pZZfIso
buff.ly/pZZfIso
Reposted by KJ
Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social
We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.
doi.org/10.1038/s415...
We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.
doi.org/10.1038/s415...
Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology
Structural and functional characterization of the β-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable β-barrel–surface lipoprotein complex assembly.
doi.org
October 2, 2025 at 6:20 AM
Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social
We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.
doi.org/10.1038/s415...
We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.
doi.org/10.1038/s415...
Reposted by KJ
🚀 Check out our new preprint on extending the scope of single-particle cryo-EM with 2D template matching!
Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching is now available on bioRxiv!
www.biorxiv.org/content/10.1...
Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching is now available on bioRxiv!
www.biorxiv.org/content/10.1...
September 17, 2025 at 5:07 PM
🚀 Check out our new preprint on extending the scope of single-particle cryo-EM with 2D template matching!
Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching is now available on bioRxiv!
www.biorxiv.org/content/10.1...
Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching is now available on bioRxiv!
www.biorxiv.org/content/10.1...
Reposted by KJ
Reposted by KJ
Bacterial cell widening alters periplasmic size and activates envelope stress responses
Kerwyn Huang, @typaslab.bsky.social et al find that E. coli outer-membrane protein RcsF senses reduced periplasm thickness due to increased cell width, & activates Rcs signaling
www.embopress.org/doi/full/10....
Kerwyn Huang, @typaslab.bsky.social et al find that E. coli outer-membrane protein RcsF senses reduced periplasm thickness due to increased cell width, & activates Rcs signaling
www.embopress.org/doi/full/10....
September 4, 2025 at 9:39 AM
Bacterial cell widening alters periplasmic size and activates envelope stress responses
Kerwyn Huang, @typaslab.bsky.social et al find that E. coli outer-membrane protein RcsF senses reduced periplasm thickness due to increased cell width, & activates Rcs signaling
www.embopress.org/doi/full/10....
Kerwyn Huang, @typaslab.bsky.social et al find that E. coli outer-membrane protein RcsF senses reduced periplasm thickness due to increased cell width, & activates Rcs signaling
www.embopress.org/doi/full/10....
Reposted by KJ
🚨 Exciting PhD Opportunities with MACSYS! The MACSYS team at Monash University is offering multiple fully funded #PhD scholarships for students eager to explore the cutting edge of computational biology, microbiology, & systems modelling.
👉More info/apply: macsys.org/monash-phd-s...
👉More info/apply: macsys.org/monash-phd-s...
May 19, 2025 at 10:51 PM
🚨 Exciting PhD Opportunities with MACSYS! The MACSYS team at Monash University is offering multiple fully funded #PhD scholarships for students eager to explore the cutting edge of computational biology, microbiology, & systems modelling.
👉More info/apply: macsys.org/monash-phd-s...
👉More info/apply: macsys.org/monash-phd-s...
Reposted by KJ
RNA is far more than a messenger.
Its structures regulate, evolve, and catalyze — carrying out functions DNA alone cannot.
But predicting #RNA structure from sequence is still extremely difficult.
In our recently published paper in @narjournal.bsky.social we present a way forward.
🧵 ⤵️
Its structures regulate, evolve, and catalyze — carrying out functions DNA alone cannot.
But predicting #RNA structure from sequence is still extremely difficult.
In our recently published paper in @narjournal.bsky.social we present a way forward.
🧵 ⤵️
August 25, 2025 at 3:02 AM
RNA is far more than a messenger.
Its structures regulate, evolve, and catalyze — carrying out functions DNA alone cannot.
But predicting #RNA structure from sequence is still extremely difficult.
In our recently published paper in @narjournal.bsky.social we present a way forward.
🧵 ⤵️
Its structures regulate, evolve, and catalyze — carrying out functions DNA alone cannot.
But predicting #RNA structure from sequence is still extremely difficult.
In our recently published paper in @narjournal.bsky.social we present a way forward.
🧵 ⤵️
Reposted by KJ
Aggresomes protect mRNA under stress in Escherichia coli
www.nature.com/articles/s41... "prolonged stress leading to ATP depletion in Escherichia coli results in increased aggresome formation, compaction and selective mRNA enrichment within these aggresomes" 🦠 #microsky #rnasky
www.nature.com/articles/s41... "prolonged stress leading to ATP depletion in Escherichia coli results in increased aggresome formation, compaction and selective mRNA enrichment within these aggresomes" 🦠 #microsky #rnasky
Aggresomes protect mRNA under stress in Escherichia coli - Nature Microbiology
Ribonucleoprotein aggresomes exclude ribonucleases and protect mRNA to promote rapid translation reactivation and cellular recovery after stress alleviation in Escherichia coli.
www.nature.com
August 23, 2025 at 8:51 AM
Aggresomes protect mRNA under stress in Escherichia coli
www.nature.com/articles/s41... "prolonged stress leading to ATP depletion in Escherichia coli results in increased aggresome formation, compaction and selective mRNA enrichment within these aggresomes" 🦠 #microsky #rnasky
www.nature.com/articles/s41... "prolonged stress leading to ATP depletion in Escherichia coli results in increased aggresome formation, compaction and selective mRNA enrichment within these aggresomes" 🦠 #microsky #rnasky
Reposted by KJ
#News&Views
Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
#MicroSky
www.nature.com/articles/s41...
Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
#MicroSky
www.nature.com/articles/s41...
Amyloids in bacterial antiphage defence - Nature Microbiology
Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
www.nature.com
August 21, 2025 at 5:47 PM
#News&Views
Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
#MicroSky
www.nature.com/articles/s41...
Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
#MicroSky
www.nature.com/articles/s41...
Reposted by KJ
Our paper is out in its final form! Back in April 2023, my coauthor Aleks Radakovic, then a PhD student, approached me after a talk in Chicago to ask what I thought an aminoacylated tRNA would look like if we pulled it through a @nanopore.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Nanopore sequencing of intact aminoacylated tRNAs - Nature Communications
Accurate protein synthesis depends on aminoacylated tRNAs, but their identities have been hard to measure. Here, authors present aa-tRNA-seq, a nanopore-based method that reveals the amino acid, seque...
doi.org
August 22, 2025 at 9:08 PM
Our paper is out in its final form! Back in April 2023, my coauthor Aleks Radakovic, then a PhD student, approached me after a talk in Chicago to ask what I thought an aminoacylated tRNA would look like if we pulled it through a @nanopore.
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by KJ
one small consolation of being a 60+ year old investigator is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays
August 14, 2025 at 12:32 AM
one small consolation of being a 60+ year old investigator is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays
Reposted by KJ
Meet the minds in MACSYS shaping the future with our series of profiles featuring our Postdoctoral Research Fellows. Dr TrungTin Nguyen is with MACSYS at QUT. His research investigates the mathematical & statistical foundations of #AI: www.linkedin.com/pulse/dr-tru...
@trungtinnguyen.bsky.social
@trungtinnguyen.bsky.social
August 12, 2025 at 5:39 AM
Meet the minds in MACSYS shaping the future with our series of profiles featuring our Postdoctoral Research Fellows. Dr TrungTin Nguyen is with MACSYS at QUT. His research investigates the mathematical & statistical foundations of #AI: www.linkedin.com/pulse/dr-tru...
@trungtinnguyen.bsky.social
@trungtinnguyen.bsky.social
Reposted by KJ
In this system, bacteria detect phage infection through a sensor protein (YjbH) and respond by severing the infected part of the cell via aberrant division. The rest of the cell survives and continues growing happily, essentially, bacterial autotomy!
August 2, 2025 at 3:01 PM
In this system, bacteria detect phage infection through a sensor protein (YjbH) and respond by severing the infected part of the cell via aberrant division. The rest of the cell survives and continues growing happily, essentially, bacterial autotomy!
Reposted by KJ
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology
Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.
www.nature.com
July 29, 2025 at 1:23 PM
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
Reposted by KJ
🍹Sharma, Jiao et al. report glycosylation of small RNAs within #exosomes and propose a glycosylation-dependent mechanism for #RNA targeting into exosomes, which may influence intercellular communication and RNA stability in the extracellular environment.
👉https://rdcu.be/eykKY
bit.ly/455vyuP
👉https://rdcu.be/eykKY
bit.ly/455vyuP
Extracellular exosomal RNAs are glyco-modified - Nature Cell Biology
Sharma, Jiao and colleagues report glycosylation of small RNAs within exosomes and propose a glycosylation-dependent mechanism for RNA targeting into exosomes, which may influence intercellular commun...
bit.ly
July 29, 2025 at 12:07 PM
🍹Sharma, Jiao et al. report glycosylation of small RNAs within #exosomes and propose a glycosylation-dependent mechanism for #RNA targeting into exosomes, which may influence intercellular communication and RNA stability in the extracellular environment.
👉https://rdcu.be/eykKY
bit.ly/455vyuP
👉https://rdcu.be/eykKY
bit.ly/455vyuP
Reposted by KJ
We have been working on ways to find #phage with long shelf-life and this one is a winner. 12 months freeze-thawing as much as you like, no loss of viability
#phageSky #microSky
rdcu.be/ewnzT
#phageSky #microSky
rdcu.be/ewnzT
Highly stable bacteriophages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria
npj Viruses - Bacteriophages (phages) are viruses that kill bacteria, with potential as antibacterial agents in industrial settings, agriculture, and human health. Here, we identified two phages,...
rdcu.be
July 17, 2025 at 1:20 PM
We have been working on ways to find #phage with long shelf-life and this one is a winner. 12 months freeze-thawing as much as you like, no loss of viability
#phageSky #microSky
rdcu.be/ewnzT
#phageSky #microSky
rdcu.be/ewnzT
Reposted by KJ
📣NAR Breakthrough Article!📣
✂️ Removal of a single tRNA^Gly gene copy in Staphylococcus aureus via CRISPR weakens the cell wall, biofilm formation and increases antibiotic susceptibility💊
📖 doi.org/10.1093/nar/...
#Microbiology #CRISPR #tRNA #AntibioticResearch #BacterialGenetics
✂️ Removal of a single tRNA^Gly gene copy in Staphylococcus aureus via CRISPR weakens the cell wall, biofilm formation and increases antibiotic susceptibility💊
📖 doi.org/10.1093/nar/...
#Microbiology #CRISPR #tRNA #AntibioticResearch #BacterialGenetics
July 14, 2025 at 3:47 PM
📣NAR Breakthrough Article!📣
✂️ Removal of a single tRNA^Gly gene copy in Staphylococcus aureus via CRISPR weakens the cell wall, biofilm formation and increases antibiotic susceptibility💊
📖 doi.org/10.1093/nar/...
#Microbiology #CRISPR #tRNA #AntibioticResearch #BacterialGenetics
✂️ Removal of a single tRNA^Gly gene copy in Staphylococcus aureus via CRISPR weakens the cell wall, biofilm formation and increases antibiotic susceptibility💊
📖 doi.org/10.1093/nar/...
#Microbiology #CRISPR #tRNA #AntibioticResearch #BacterialGenetics
Reposted by KJ
Check out these amazing lipid-monolayer-trapping oligomeric OMPs published by @lalouxlab.bsky.social and Lovering Labs. The BAM complex in these bugs must be wild!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily - Nature Communications
This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows the discovery of two superfa...
www.nature.com
July 6, 2025 at 6:54 AM
Check out these amazing lipid-monolayer-trapping oligomeric OMPs published by @lalouxlab.bsky.social and Lovering Labs. The BAM complex in these bugs must be wild!
www.nature.com/articles/s41...
www.nature.com/articles/s41...