Nature Cell Biology
@natcellbio.nature.com
A journal dedicated to publishing the latest advances across all areas of cell biology. Part of @natureportfolio.nature.com
nature.com/ncb/index.html
nature.com/ncb/index.html
Pinned
🎄Our last issue for 2025 is out!
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
☕Benito-Martínez, @laurasalavessa.bsky.social et al show that #keratin intermediate filaments and #microtubules control the 3D perinuclear position of melanin-containing #organelles, shielding the DNA from #photodamage. @delevoyecedric.bsky.social
👉https://rdcu.be/eWY06
bit.ly/45x0GEx
👉https://rdcu.be/eWY06
bit.ly/45x0GEx
Keratin intermediate filaments mechanically position melanin pigments for genome photoprotection - Nature Cell Biology
Benito-Martínez, Salavessa and colleagues show that keratin intermediate filaments and microtubules control the three-dimensional perinuclear position of melanin-containing organelles, shielding the D...
bit.ly
December 30, 2025 at 5:30 PM
☕Benito-Martínez, @laurasalavessa.bsky.social et al show that #keratin intermediate filaments and #microtubules control the 3D perinuclear position of melanin-containing #organelles, shielding the DNA from #photodamage. @delevoyecedric.bsky.social
👉https://rdcu.be/eWY06
bit.ly/45x0GEx
👉https://rdcu.be/eWY06
bit.ly/45x0GEx
☕Cornell et al. show that target cells with low cortical tension induce #macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high #CorticalTension tend towards #phagocytosis.
bit.ly/3L7xFIO
bit.ly/3L7xFIO
Target cell cortical tension regulates macrophage trogocytosis - Nature Cell Biology
Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...
bit.ly
December 30, 2025 at 5:23 PM
☕Cornell et al. show that target cells with low cortical tension induce #macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high #CorticalTension tend towards #phagocytosis.
bit.ly/3L7xFIO
bit.ly/3L7xFIO
☕Shen, @zgelashvili.bsky.social and Niethammer developed an inner #NuclearMembrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.
bit.ly/3MZM6PF
bit.ly/3MZM6PF
Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction - Nature Cell Biology
Shen, Gelashvili and Niethammer developed an inner nuclear membrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.
bit.ly
December 30, 2025 at 5:18 PM
☕Shen, @zgelashvili.bsky.social and Niethammer developed an inner #NuclearMembrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.
bit.ly/3MZM6PF
bit.ly/3MZM6PF
Reposted by Nature Cell Biology
Drs. Komal Makwana, Louise Tilley, and the @nmoris.bsky.social lab at the @crick.ac.uk developed human trunk-like structures to model somite and #neural tube co-development.
🔖 @natcellbio.nature.com - https://go.nature.com/4qsAmUd
🎙️ - https://bit.ly/4p3izlj
🔖 @natcellbio.nature.com - https://go.nature.com/4qsAmUd
🎙️ - https://bit.ly/4p3izlj
December 30, 2025 at 5:10 PM
Drs. Komal Makwana, Louise Tilley, and the @nmoris.bsky.social lab at the @crick.ac.uk developed human trunk-like structures to model somite and #neural tube co-development.
🔖 @natcellbio.nature.com - https://go.nature.com/4qsAmUd
🎙️ - https://bit.ly/4p3izlj
🔖 @natcellbio.nature.com - https://go.nature.com/4qsAmUd
🎙️ - https://bit.ly/4p3izlj
☕The authors optimize an in vitro human #epiblast model, which they utilize to show that early #TGFβ family inhibition prevents epithelial identity, while it is dispensable after epithelium formation. @grazianomartello.bsky.social
👉https://rdcu.be/eVPMa
bit.ly/4pNo2xL
👉https://rdcu.be/eVPMa
bit.ly/4pNo2xL
A human epiblast model reveals dynamic TGFβ-mediated control of epithelial identity during mammalian epiblast development - Nature Cell Biology
The authors optimize an in vitro human epiblast model, which they utilize to show that early TGFβ family inhibition prevents epithelial identity, whereas it is dispensable after epithelium formation. ...
bit.ly
December 22, 2025 at 11:31 AM
☕The authors optimize an in vitro human #epiblast model, which they utilize to show that early #TGFβ family inhibition prevents epithelial identity, while it is dispensable after epithelium formation. @grazianomartello.bsky.social
👉https://rdcu.be/eVPMa
bit.ly/4pNo2xL
👉https://rdcu.be/eVPMa
bit.ly/4pNo2xL
☕Kozai, Fernandez-Martinez et al. use high-speed atomic force #microscopy to study the permeability barrier of yeast #NuclearPore complexes. They show that #karyopherins remodel a central plug that shapes barrier dynamics and disorder within the pore.
bit.ly/4p9LXGS
bit.ly/4p9LXGS
Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier - Nature Cell Biology
Kozai, Fernandez-Martinez et al. use high-speed atomic force microscopy to study the permeability barrier of yeast nuclear pore complexes. They show that karyopherins remodel a central plug that shape...
bit.ly
December 22, 2025 at 11:28 AM
☕Kozai, Fernandez-Martinez et al. use high-speed atomic force #microscopy to study the permeability barrier of yeast #NuclearPore complexes. They show that #karyopherins remodel a central plug that shapes barrier dynamics and disorder within the pore.
bit.ly/4p9LXGS
bit.ly/4p9LXGS
☕Zhou, Jay et al. report that in mantle cell #lymphoma and T cell #leukemia, lineage-determining #TranscriptionFactors share a mechanism to regulate how multiple enhancers control oncogene expression through topological conformation and interaction.
👉https://rdcu.be/eVPIk
bit.ly/4p3cBAT
👉https://rdcu.be/eVPIk
bit.ly/4p3cBAT
Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation - Nature Cell Biology
Zhou, Jay et al. report that in mantle cell lymphoma and T cell leukaemia, lineage-determining transcription factors share a mechanism to regulate how multiple enhancers control oncogene expression th...
bit.ly
December 22, 2025 at 11:26 AM
☕Zhou, Jay et al. report that in mantle cell #lymphoma and T cell #leukemia, lineage-determining #TranscriptionFactors share a mechanism to regulate how multiple enhancers control oncogene expression through topological conformation and interaction.
👉https://rdcu.be/eVPIk
bit.ly/4p3cBAT
👉https://rdcu.be/eVPIk
bit.ly/4p3cBAT
☕Treekitkarnmongkol, Katayama, Sankaran et al. identify RASH3D19 as a downstream target for #KRAS signaling through miR-301a, which leads to RAS activation & tumorigenesis. Targeting RASH3D19 inhibits growth of KRAS-mutant tumor cells in vivo. #PancreaticCancer
👉https://rdcu.be/eVPDm
bit.ly/4qlc7qU
👉https://rdcu.be/eVPDm
bit.ly/4qlc7qU
RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer - Nature Cell Biology
Treekitkarnmongkol, Katayama, Sankaran et al. identify RASH3D19 as a downstream target for KRAS signalling through miR-301a, which in turn leads to RAS activation and tumorigenesis. Targeting RASH3D19...
bit.ly
December 22, 2025 at 11:21 AM
☕Treekitkarnmongkol, Katayama, Sankaran et al. identify RASH3D19 as a downstream target for #KRAS signaling through miR-301a, which leads to RAS activation & tumorigenesis. Targeting RASH3D19 inhibits growth of KRAS-mutant tumor cells in vivo. #PancreaticCancer
👉https://rdcu.be/eVPDm
bit.ly/4qlc7qU
👉https://rdcu.be/eVPDm
bit.ly/4qlc7qU
🎄Our last issue for 2025 is out!
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
December 19, 2025 at 7:22 PM
🎄Our last issue for 2025 is out!
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
☕The composition of #ExtracellularVesicles (EVs) is central to their function, yet the field lacks systematic characterization. Here Rai et al. perform #proteomic and #lipidomic analyses of circulating human #plasma EVs and create a web tool for data exploration.
bit.ly/3N7xm0Y
bit.ly/3N7xm0Y
Multi-omics identify hallmark protein and lipid features of small extracellular vesicles circulating in human plasma - Nature Cell Biology
The composition of extracellular vesicles (EVs) is central to their function, yet the field lacks systematic characterization. Here Rai et al. perform proteomic and lipidomic analyses of circulating h...
bit.ly
December 17, 2025 at 8:51 PM
☕The composition of #ExtracellularVesicles (EVs) is central to their function, yet the field lacks systematic characterization. Here Rai et al. perform #proteomic and #lipidomic analyses of circulating human #plasma EVs and create a web tool for data exploration.
bit.ly/3N7xm0Y
bit.ly/3N7xm0Y
☕Liu, Qu, Liu et al report an m7G-independent function of WDR4 in regulating translation machinery and #cholesterol homeostasis in tumor-associated #macrophages. They develop a targeting strategy using CpG-small interfering RNA to suppress #tumor progression.
👉https://rdcu.be/eVbon
bit.ly/4aX9aZ7
👉https://rdcu.be/eVbon
bit.ly/4aX9aZ7
WDR4 drives tumour-associated macrophage reprogramming and tumour progression via selective translation and membrane cholesterol efflux - Nature Cell Biology
J. Liu, C. Qu, Y. Liu and colleagues report an m7G-independent function of WDR4 in regulating translation machinery and cholesterol homeostasis in tumour-associated macrophages. They develop a targeti...
bit.ly
December 17, 2025 at 8:46 PM
☕Liu, Qu, Liu et al report an m7G-independent function of WDR4 in regulating translation machinery and #cholesterol homeostasis in tumor-associated #macrophages. They develop a targeting strategy using CpG-small interfering RNA to suppress #tumor progression.
👉https://rdcu.be/eVbon
bit.ly/4aX9aZ7
👉https://rdcu.be/eVbon
bit.ly/4aX9aZ7
☕Li, Li, Wu et al. use a proteomics approach, PhastID to identify protein components of nuclear condensates (NCs). They reveal crosstalk between NCs, the dynamics of condensate components and identify an NC formed by BUD13.
👉https://rdcu.be/eVboa
bit.ly/3N7wUzO
👉https://rdcu.be/eVboa
bit.ly/3N7wUzO
Proximal proteomics reveals a landscape of human nuclear condensates - Nature Cell Biology
Li, Li, Wu et al. use a proteomics approach, PhastID to identify protein components of nuclear condensates (NCs). They reveal crosstalk between NCs, the dynamics of condensate components and identify ...
bit.ly
December 17, 2025 at 8:42 PM
☕Li, Li, Wu et al. use a proteomics approach, PhastID to identify protein components of nuclear condensates (NCs). They reveal crosstalk between NCs, the dynamics of condensate components and identify an NC formed by BUD13.
👉https://rdcu.be/eVboa
bit.ly/3N7wUzO
👉https://rdcu.be/eVboa
bit.ly/3N7wUzO
Reposted by Nature Cell Biology
Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...
Modelling co-development between the somites and neural tube in human trunk-like structures - Nature Cell Biology
Makwana, Tilley et al. generate human stem cell-based trunk-like structures approximating Carnegie stage 13–14 of development. They use them to model and study the development of the thoracic and lumbar trunk.
www.nature.com
December 16, 2025 at 10:04 AM
Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...
☕@drmingyaoli.bsky.social & co present S2-omics, an end-to-end workflow that automatically identifies regions of interest in histology images to maximize molecular information capture in spatial omics experiments.
bit.ly/4j2rIcG
bit.ly/4j2rIcG
Smart spatial omics (S2-omics) optimizes region of interest selection to capture molecular heterogeneity in diverse tissues - Nature Cell Biology
Yuan et al. present S2-omics, an end-to-end workflow that automatically identifies regions of interest in histology images to maximize molecular information capture in spatial omics experiments.
bit.ly
December 16, 2025 at 10:16 PM
☕@drmingyaoli.bsky.social & co present S2-omics, an end-to-end workflow that automatically identifies regions of interest in histology images to maximize molecular information capture in spatial omics experiments.
bit.ly/4j2rIcG
bit.ly/4j2rIcG
☕Minetti, Omrani et al. report that delayed #intestinal #regeneration results from protein homeostasis stress and can be improved by modulation of the #polyamine pathway dynamics.
bit.ly/3N38jfy
bit.ly/3N38jfy
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis - Nature Cell Biology
Minetti, Omrani et al. report that delayed intestinal regeneration results from protein homeostasis stress and can be improved by modulation of the polyamine pathway dynamics.
bit.ly
December 16, 2025 at 10:13 PM
☕Minetti, Omrani et al. report that delayed #intestinal #regeneration results from protein homeostasis stress and can be improved by modulation of the #polyamine pathway dynamics.
bit.ly/3N38jfy
bit.ly/3N38jfy
☕Rajshekar et al. show that a hierarchy of affinities layers pericentromeric heterochromatin around nucleoli, with the RNA helicase Pitchoune (DDX18) acting as a key dual-affinity linker in Drosophila melanogaster.
bit.ly/45dz7Qt
bit.ly/45dz7Qt
Hierarchical interactions between nucleolar and heterochromatin condensates are mediated by a dual-affinity protein - Nature Cell Biology
Rajshekar et al. show that a hierarchy of affinities layers pericentromeric heterochromatin around nucleoli, with the RNA helicase Pitchoune (DDX18) acting as a key dual-affinity linker in Drosophila ...
bit.ly
December 16, 2025 at 10:12 PM
☕Rajshekar et al. show that a hierarchy of affinities layers pericentromeric heterochromatin around nucleoli, with the RNA helicase Pitchoune (DDX18) acting as a key dual-affinity linker in Drosophila melanogaster.
bit.ly/45dz7Qt
bit.ly/45dz7Qt
☕Xu et al. identify REPRODUCTIVE MERISTEM #TranscriptionFactors that are required for RNA-directed #DNAmethylation at CLASSY3 target loci in male and female reproductive tissues of Arabidopsis.
bit.ly/4iYqr6d
bit.ly/4iYqr6d
Transcription factors instruct DNA methylation patterns in plant reproductive tissues - Nature Cell Biology
Xu et al. identify REPRODUCTIVE MERISTEM transcription factors that are required for RNA-directed DNA methylation at CLASSY3 target loci in male and female reproductive tissues of Arabidopsis.
bit.ly
December 16, 2025 at 10:10 PM
☕Xu et al. identify REPRODUCTIVE MERISTEM #TranscriptionFactors that are required for RNA-directed #DNAmethylation at CLASSY3 target loci in male and female reproductive tissues of Arabidopsis.
bit.ly/4iYqr6d
bit.ly/4iYqr6d
☕Sankaran (@bloodgenes.bsky.social) & co augment the ex vivo expansion potential of human #hematopoietic #StemCells (HSCs) by inhibiting #ferroptosis with liproxstatin-1 or ferrostatin-1. Treated HSCs have enhanced in vivo repopulation capacity.
bit.ly/4pEAzU9
bit.ly/4pEAzU9
Inhibiting ferroptosis enhances ex vivo expansion of human haematopoietic stem cells - Nature Cell Biology
della Volpe et al. augment the ex vivo expansion potential of human haematopoietic stem cells (HSCs) by inhibiting ferroptosis with liproxstatin-1 or ferrostatin-1. Treated HSCs have enhanced in vivo ...
bit.ly
December 16, 2025 at 10:05 PM
☕Sankaran (@bloodgenes.bsky.social) & co augment the ex vivo expansion potential of human #hematopoietic #StemCells (HSCs) by inhibiting #ferroptosis with liproxstatin-1 or ferrostatin-1. Treated HSCs have enhanced in vivo repopulation capacity.
bit.ly/4pEAzU9
bit.ly/4pEAzU9
Reposted by Nature Cell Biology
In time for the ATCC centennial, Ruth Cheng+Rebecca Bradford fr American Type Culture Collection write @natcellbio.nature.com: the importance of nonprofit resources (like ATCC) to provide access, set global standards, champion innovation. For now & the future.
Link to read for free: rdcu.be/eUd9R
Link to read for free: rdcu.be/eUd9R
A foundation for tomorrow’s discoveries in cell biology - Nature Cell Biology
For a century, the American Type Culture Collection (ATCC) has been an essential resource for biologists, fuelling discoveries in areas from cancer to infectious diseases. In this Comment, we outline ...
www.nature.com
December 11, 2025 at 1:32 PM
In time for the ATCC centennial, Ruth Cheng+Rebecca Bradford fr American Type Culture Collection write @natcellbio.nature.com: the importance of nonprofit resources (like ATCC) to provide access, set global standards, champion innovation. For now & the future.
Link to read for free: rdcu.be/eUd9R
Link to read for free: rdcu.be/eUd9R
Reposted by Nature Cell Biology
This month I complete 4 years as an editor at @natcellbio.nature.com. It’s hard to express how grateful I am for the things I ‘ve learnt, the incredible projects I ‘ve had the honor to be a part of, the wonderful people I ‘ve met in my journey so far and the very inspiring interactions I ‘ve had.
December 5, 2025 at 2:27 AM
This month I complete 4 years as an editor at @natcellbio.nature.com. It’s hard to express how grateful I am for the things I ‘ve learnt, the incredible projects I ‘ve had the honor to be a part of, the wonderful people I ‘ve met in my journey so far and the very inspiring interactions I ‘ve had.
Reposted by Nature Cell Biology
🥂Congrats to Ori, Neri & co for their new Open Access study in our journal @natcellbio.nature.com showing that delayed #intestinal #regeneration results from protein homeostasis stress and can be improved by modulation of the #polyamine pathway dynamics.
bit.ly/3YhxZHC
bit.ly/3YhxZHC
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis - Nature Cell Biology
Minetti, Omrani et al. report that delayed intestinal regeneration results from protein homeostasis stress and can be improved by modulation of the polyamine pathway dynamics.
bit.ly
December 7, 2025 at 10:32 AM
🥂Congrats to Ori, Neri & co for their new Open Access study in our journal @natcellbio.nature.com showing that delayed #intestinal #regeneration results from protein homeostasis stress and can be improved by modulation of the #polyamine pathway dynamics.
bit.ly/3YhxZHC
bit.ly/3YhxZHC
☕Williams et al. report a growth arrest mechanism in residual #cancer persister cells through targeted #therapy - induced upregulation of type I #interferon signalling, which is negatively regulated by apoptotic DNA endonuclease DFFB to allow tumour relapse.
bit.ly/4aibIAN
bit.ly/4aibIAN
DNA fragmentation factor B suppresses interferon to enable cancer persister cell regrowth - Nature Cell Biology
Williams et al. report a growth arrest mechanism in residual cancer persister cells through targeted therapy-induced upregulation of type I interferon signalling, which is negatively regulated by apop...
bit.ly
November 27, 2025 at 4:12 PM
☕Williams et al. report a growth arrest mechanism in residual #cancer persister cells through targeted #therapy - induced upregulation of type I #interferon signalling, which is negatively regulated by apoptotic DNA endonuclease DFFB to allow tumour relapse.
bit.ly/4aibIAN
bit.ly/4aibIAN
☕Lu, Wang et al. profile H3K36me2 throughout #oocyte -to- #embryo transition, pre-implantation and early post-implantation development and report a role for H3K36me2 in post-implantation embryos to re-establish lineage-specific #DNAmethylation.
👉https://rdcu.be/eR6N1
bit.ly/4py2wwz
👉https://rdcu.be/eR6N1
bit.ly/4py2wwz
Reprogramming of H3K36me2 guides lineage-specific post-implantation de novo DNA methylation - Nature Cell Biology
Lu, Wang et al. profile H3K36me2 throughout oocyte-to-embryo transition, pre-implantation and early post-implantation development and report a role for H3K36me2 in post-implantation embryos to re-esta...
bit.ly
November 27, 2025 at 4:08 PM
☕Lu, Wang et al. profile H3K36me2 throughout #oocyte -to- #embryo transition, pre-implantation and early post-implantation development and report a role for H3K36me2 in post-implantation embryos to re-establish lineage-specific #DNAmethylation.
👉https://rdcu.be/eR6N1
bit.ly/4py2wwz
👉https://rdcu.be/eR6N1
bit.ly/4py2wwz
☕Lee et al. show that Ca²⁺ triggers condensates enriched with PDIA6, an ER-resident disulfide isomerase and chaperone, along with other protein disulfide isomerase family proteins and some chaperones that in turn enhance folding of #proinsulin. #PhaseSeparation
bit.ly/44mX1bW
bit.ly/44mX1bW
Ca2+-driven PDIA6 biomolecular condensation ensures proinsulin folding - Nature Cell Biology
Lee et al. show that Ca²⁺ triggers condensates enriched with PDIA6, an ER-resident disulfide isomerase and chaperone, along with other protein disulfide isomerase family proteins and some chaperones t...
bit.ly
November 27, 2025 at 9:31 AM
☕Lee et al. show that Ca²⁺ triggers condensates enriched with PDIA6, an ER-resident disulfide isomerase and chaperone, along with other protein disulfide isomerase family proteins and some chaperones that in turn enhance folding of #proinsulin. #PhaseSeparation
bit.ly/44mX1bW
bit.ly/44mX1bW
☕Zhou et al. design protein-based artificial #kinetochore constructs as decoys to prevent premature #chromosomal separation in aged #oocytes. These constructs compete with chromosomal kinetochores, reducing excessive bipolar #microtubule pulling forces.
bit.ly/48g0oTa
bit.ly/48g0oTa
Designing protein-based artificial kinetochores as decoys to prevent meiotic errors in oocytes - Nature Cell Biology
Zhou et al. design protein-based artificial kinetochore constructs as decoys to prevent premature chromosomal separation in aged oocytes. These constructs compete with chromosomal kinetochores, reduci...
bit.ly
November 27, 2025 at 9:22 AM
☕Zhou et al. design protein-based artificial #kinetochore constructs as decoys to prevent premature #chromosomal separation in aged #oocytes. These constructs compete with chromosomal kinetochores, reducing excessive bipolar #microtubule pulling forces.
bit.ly/48g0oTa
bit.ly/48g0oTa