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Nature Cell Biology
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A journal dedicated to publishing the latest advances across all areas of cell biology. Part of @natureportfolio.nature.com
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🍰Interested in reading more? Here's the Research Briefing.
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Senescence-coupled differentiation selectively eliminates cancer-prone stem cells - Nature Cell Biology
Ageing and cancer are often seen as divergent tissue fates. In our study, we identify a protective programme, called senescence-coupled differentiation (or seno-differentiation), that eliminates cance...
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November 6, 2025 at 1:41 PM
🍰Interested in reading more? Here's the Research Briefing.
👉https://rdcu.be/eOALm
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Navigating cell state transitions with deep learning - Nature Cell Biology
We present CellNavi, a deep learning framework that predicts driver genes that orchestrate cellular transitions by modelling cell states on a biologically meaningful manifold. We demonstrated how Cell...
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November 6, 2025 at 1:37 PM
🍰Interested in reading more? Here is the N&Vs article on the study, written by Yonglong Dang, Yuk Kit Lor & Gonçalo Castelo-Branco:
👉https://rdcu.be/eOgSd
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Cracking glioblastoma core regulatory codes - Nature Cell Biology
Glioblastoma (GBM) heterogeneity might arise because of the activation of various gene core regulatory circuitries (CRCs). A new study highlights the central role of HOXB3 in GBM CRCs and how peptide-...
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November 4, 2025 at 6:28 PM
☕🍰Interested in reading more about the study? Here is the N&Vs article written by Roberto Mayor.
👉https://rdcu.be/eJqR1
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Forcing cell fate - Nature Cell Biology
The transition of a pluripotent stem cell into a differentiated lineage is one of the most complex yet precisely orchestrated events in developmental biology. A study now reveals that mechanical and osmotic forces, long considered background players in guiding this transition, are essential regulators of chromatin accessibility and cell fate decisions.
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October 4, 2025 at 2:40 PM
☕🍰Interested in reading more about the study? Here is the N&Vs article written by Sebastian Rumpf & Neeraja Sanal.
👉https://rdcu.be/eJqMg
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AMPK signalling integrated in growth control - Nature Cell Biology
The AMP-dependent protein kinase AMPK is thought to be activated only when cellular energy levels are low. However, a study now finds that intracellular AMP is generated from extracellular adenosine in an intricate growth signalling cascade, explaining how AMPK can be regulated by extracellular cues.
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October 4, 2025 at 2:32 PM