ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
Physician-scientist at UC San Diego, Microbiology, Immunology, Novel Drug and Vaccine Discovery, #IDSky, Mentoring and Supporting STEM Career Development.
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
Pinned
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
· Mar 2
this is the ideal bacterial morphology
you may not like it, but this is what peak performance looks like
you may not like it, but this is what peak performance looks like
Lionfish at the Birch Aquarium of our Scripps Institution of Oceanography, here at the University of California, San Diego. Very beautiful and very venomous.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
November 15, 2025 at 10:29 PM
Lionfish at the Birch Aquarium of our Scripps Institution of Oceanography, here at the University of California, San Diego. Very beautiful and very venomous.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Always a treat to visit Birch, a special place that exemplifies SIO/UCSD's public educational outreach.
Important update below on the eligibility criteria for the current round of funding from CARB-X, the hugely impactful accelerator for novel therapeutics, preventatives, and diagnostics to confront the AMR crisis. CARB-X can provide not only funding, but deep expertise to help companies succeed.
November 13, 2025 at 6:27 PM
Important update below on the eligibility criteria for the current round of funding from CARB-X, the hugely impactful accelerator for novel therapeutics, preventatives, and diagnostics to confront the AMR crisis. CARB-X can provide not only funding, but deep expertise to help companies succeed.
Most wildlife crimes vs gulls committed by men
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
November 13, 2025 at 4:47 PM
Most wildlife crimes vs gulls committed by men
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
New study: five British men recorded saying "𝐍𝐨! 𝐒𝐭𝐚𝐲 𝐚𝐰𝐚𝐲! 𝐓𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐟𝐨𝐨𝐝—𝐭𝐡𝐚𝐭'𝐬 𝐦𝐲 𝐩𝐚𝐬𝐭𝐲!" in SHOUTING VOICE vs neutral "speaking" voice. Shouting effective!
royalsocietypublishing.org/doi/10.1098/...
We'll try with "fish taco" in San Diego cohort
Pleased to share our new work, spearheaded by Drs. Alex Hoffman and Elisabet Bjånes—in collaboration with the Liangfang Zhang Lab, Cellics Therapeutics, and CARB-X—debuting CTI-111, a biomimetic macrophage membrane-coated nanoparticle and candidate broad-spectrum adjunctive therapy for sepsis
🧵 1/4
🧵 1/4
November 11, 2025 at 11:25 PM
Pleased to share our new work, spearheaded by Drs. Alex Hoffman and Elisabet Bjånes—in collaboration with the Liangfang Zhang Lab, Cellics Therapeutics, and CARB-X—debuting CTI-111, a biomimetic macrophage membrane-coated nanoparticle and candidate broad-spectrum adjunctive therapy for sepsis
🧵 1/4
🧵 1/4
A visit to the University of Lausanne (UNIL) allowed me to drop in on my close colleague and former sabbatical professor Jan-Willem Veening's lab in the Department of Fundamental Microbiology, Biophore Building.
The view is not too bad!
The view is not too bad!
November 10, 2025 at 7:33 PM
A visit to the University of Lausanne (UNIL) allowed me to drop in on my close colleague and former sabbatical professor Jan-Willem Veening's lab in the Department of Fundamental Microbiology, Biophore Building.
The view is not too bad!
The view is not too bad!
Very proud to be on the leadership of this outstanding program, recently successful in its competitive renewal from the NIH, that provides grant writing and career development mentorship for junior faculty ID researchers from around the country! Summer bootcamps in beautiful La Jolla!
⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️
⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️
Applications for UC San Diego RAPID program's 2026-27 cohort are now open! This highly-rated and effective career development opportunity is for junior faculty researchers in #InfectiousDiseases.
Learn more and apply today at rapid.ucsd.edu!
#UCSD_RAPID #FacultyDevelopment
Learn more and apply today at rapid.ucsd.edu!
#UCSD_RAPID #FacultyDevelopment
November 3, 2025 at 6:15 PM
Very proud to be on the leadership of this outstanding program, recently successful in its competitive renewal from the NIH, that provides grant writing and career development mentorship for junior faculty ID researchers from around the country! Summer bootcamps in beautiful La Jolla!
⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️
⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️ ⬇️
impact factor is the drug, and we scientists, our institutions, and funding bodies have become addicted
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
November 2, 2025 at 1:49 PM
impact factor is the drug, and we scientists, our institutions, and funding bodies have become addicted
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
as federal funding becomes scarcer, it's important to prioritize available resources are directed to experimental discovery and trainee support above glamorization and exorbitant page charges
DIPPIN' DOTS were never the future but maybe this is
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
November 2, 2025 at 12:16 PM
DIPPIN' DOTS were never the future but maybe this is
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
McMaster U 🇨🇦 Science Advances
BACTERIOPHAGE-LOADED MICRONEEDLES that enable safe phage delivery directly into food matrices
Multi-log reduction in E. coli CFU in raw hamburger or cooked ready-to-eat chicken
www.science.org/doi/10.1126/...
Great Egret (Ardea alba) in same spot that I saw blue heron last week. These guys are 3 feet tall with 5 foot wingspan but only weigh 2.5 to 3 pounds. Pure biological efficiency. #birds 🪶
November 1, 2025 at 3:20 PM
Great Egret (Ardea alba) in same spot that I saw blue heron last week. These guys are 3 feet tall with 5 foot wingspan but only weigh 2.5 to 3 pounds. Pure biological efficiency. #birds 🪶
very stately coyote I just met on a canyon trail near our home
October 31, 2025 at 1:35 AM
very stately coyote I just met on a canyon trail near our home
CHECK IT OUT
Nat Comm study UCLA team
gut 🦠 <-> brain 🧠 axis
Internalizing symptoms—anxiety, sadness, withdrawal—in childhood link to early gut microbiome patterns
⬆️ Clostridiales / Lachnospiraceae at age 2 predict later changes in emotion-related brain network connectivity and symptom levels
Nat Comm study UCLA team
gut 🦠 <-> brain 🧠 axis
Internalizing symptoms—anxiety, sadness, withdrawal—in childhood link to early gut microbiome patterns
⬆️ Clostridiales / Lachnospiraceae at age 2 predict later changes in emotion-related brain network connectivity and symptom levels
Childhood gut microbiome is linked to internalizing symptoms at school age via the functional connectome - Nature Communications
Here, the authors find that relative abundances of stress-sensitive gastrointestinal microbes at age 2 years predicts internalizing symptoms in middle childhood through altered emotion-related brain n...
www.nature.com
October 30, 2025 at 1:12 PM
CHECK IT OUT
Nat Comm study UCLA team
gut 🦠 <-> brain 🧠 axis
Internalizing symptoms—anxiety, sadness, withdrawal—in childhood link to early gut microbiome patterns
⬆️ Clostridiales / Lachnospiraceae at age 2 predict later changes in emotion-related brain network connectivity and symptom levels
Nat Comm study UCLA team
gut 🦠 <-> brain 🧠 axis
Internalizing symptoms—anxiety, sadness, withdrawal—in childhood link to early gut microbiome patterns
⬆️ Clostridiales / Lachnospiraceae at age 2 predict later changes in emotion-related brain network connectivity and symptom levels
Celebratory lab luncheon for Hervé Besançon, who completed his SNSF 🇨🇭 postdoc with us here in La Jolla. In addition to his good cheer and Swiss panache, he made fantastic contributions to our nanovaccine studies
Expert by birthright, Hervé taught proper fondue technique at the chocolate fountain
Expert by birthright, Hervé taught proper fondue technique at the chocolate fountain
October 30, 2025 at 1:56 AM
Celebratory lab luncheon for Hervé Besançon, who completed his SNSF 🇨🇭 postdoc with us here in La Jolla. In addition to his good cheer and Swiss panache, he made fantastic contributions to our nanovaccine studies
Expert by birthright, Hervé taught proper fondue technique at the chocolate fountain
Expert by birthright, Hervé taught proper fondue technique at the chocolate fountain
Cool 🦠
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation - Nature Microbiology
Opposing forces generated by exopolysaccharide trail binding versus type IV pilus retraction generate a high cyclic diGMP–high cyclic AMP state in Pseudomonas aeruginosa that promotes social motility.
www.nature.com
October 29, 2025 at 3:41 AM
Cool 🦠
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
36 years ago I did a medical student rotation at Black River Hospital in St. Elizabeth Parish, Jamaica 🇯🇲 to work with and learn from the kind and wonderful doctors, nurses, and patients
They are on track for a direct eyewall hit from hurricane Melissa tomorrow—sending thoughts of love and strength
They are on track for a direct eyewall hit from hurricane Melissa tomorrow—sending thoughts of love and strength
October 28, 2025 at 3:19 AM
36 years ago I did a medical student rotation at Black River Hospital in St. Elizabeth Parish, Jamaica 🇯🇲 to work with and learn from the kind and wonderful doctors, nurses, and patients
They are on track for a direct eyewall hit from hurricane Melissa tomorrow—sending thoughts of love and strength
They are on track for a direct eyewall hit from hurricane Melissa tomorrow—sending thoughts of love and strength
like the (often unfair) stereotype of southern californians, these quail on our backyard planter seem pretty superficial and focused on their appearance—just preening and chirping, preening and chirping
October 27, 2025 at 12:07 PM
like the (often unfair) stereotype of southern californians, these quail on our backyard planter seem pretty superficial and focused on their appearance—just preening and chirping, preening and chirping
worried someone might have stolen some of our research ideas so I've engaged a special investigator
October 27, 2025 at 1:25 AM
worried someone might have stolen some of our research ideas so I've engaged a special investigator
great blue heron unperturbed by my proximity this morning in pacific highlands ranch, san diego
October 26, 2025 at 4:36 PM
great blue heron unperturbed by my proximity this morning in pacific highlands ranch, san diego
October 26, 2025 at 4:46 AM
The most abundant birds in our backyard are beautiful mourning doves (Zenaida macroura), which are monogamous and mate for life.
Fun fact: Both male and female mourning doves produce a nutritious, high-protein secretion known as "crop milk," to feed their young for the first few days of life.
Fun fact: Both male and female mourning doves produce a nutritious, high-protein secretion known as "crop milk," to feed their young for the first few days of life.
October 25, 2025 at 3:41 PM
The most abundant birds in our backyard are beautiful mourning doves (Zenaida macroura), which are monogamous and mate for life.
Fun fact: Both male and female mourning doves produce a nutritious, high-protein secretion known as "crop milk," to feed their young for the first few days of life.
Fun fact: Both male and female mourning doves produce a nutritious, high-protein secretion known as "crop milk," to feed their young for the first few days of life.
Lab of former postdoc Yujiro Hirose @Osaka Univ used genome-scale modeling and infection studies show dextrin acts as a regulatory signal—linking metabolic adaptation to toxin expression through the CovRS system in Group A 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴.
urldefense.com/v3/__https:/...
urldefense.com/v3/__https:/...
October 22, 2025 at 4:20 AM
Lab of former postdoc Yujiro Hirose @Osaka Univ used genome-scale modeling and infection studies show dextrin acts as a regulatory signal—linking metabolic adaptation to toxin expression through the CovRS system in Group A 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴.
urldefense.com/v3/__https:/...
urldefense.com/v3/__https:/...
🇳🇱👩🎓🔬🧬🧫🎉👏🇳🇱
Congratulations to our former MS student Sara Tamminga on the successful defense of her PhD in the laboratory of our former postdoctoral scholar Nina van Sorge at Amsterdam UMC!
Next stop for Sara — a scientist position at GenDx in Utrecht.
Gefeliciteerd Sara en Nina!
Congratulations to our former MS student Sara Tamminga on the successful defense of her PhD in the laboratory of our former postdoctoral scholar Nina van Sorge at Amsterdam UMC!
Next stop for Sara — a scientist position at GenDx in Utrecht.
Gefeliciteerd Sara en Nina!
October 21, 2025 at 12:50 PM
🇳🇱👩🎓🔬🧬🧫🎉👏🇳🇱
Congratulations to our former MS student Sara Tamminga on the successful defense of her PhD in the laboratory of our former postdoctoral scholar Nina van Sorge at Amsterdam UMC!
Next stop for Sara — a scientist position at GenDx in Utrecht.
Gefeliciteerd Sara en Nina!
Congratulations to our former MS student Sara Tamminga on the successful defense of her PhD in the laboratory of our former postdoctoral scholar Nina van Sorge at Amsterdam UMC!
Next stop for Sara — a scientist position at GenDx in Utrecht.
Gefeliciteerd Sara en Nina!
Ⓜⓘⓒⓡⓞⓑⓘⓐⓛ ⓞⓡⓘⓖⓘⓝⓢ
ⓞⓕ Ⓟⓐⓡⓚⓘⓝⓢⓞⓝ 'ⓢ
Nat Comm: 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘮𝘶𝘵𝘢𝘯𝘴 a driver of Parkinson’s disease?
Its enzyme UrdA generates imidazole propionate (ImP), which enters the brain, activates mTORC1, triggering α-synuclein aggregation and dopaminergic neuron loss
www.nature.com/articles/s41...
ⓞⓕ Ⓟⓐⓡⓚⓘⓝⓢⓞⓝ 'ⓢ
Nat Comm: 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘮𝘶𝘵𝘢𝘯𝘴 a driver of Parkinson’s disease?
Its enzyme UrdA generates imidazole propionate (ImP), which enters the brain, activates mTORC1, triggering α-synuclein aggregation and dopaminergic neuron loss
www.nature.com/articles/s41...
October 20, 2025 at 3:59 AM
Ⓜⓘⓒⓡⓞⓑⓘⓐⓛ ⓞⓡⓘⓖⓘⓝⓢ
ⓞⓕ Ⓟⓐⓡⓚⓘⓝⓢⓞⓝ 'ⓢ
Nat Comm: 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘮𝘶𝘵𝘢𝘯𝘴 a driver of Parkinson’s disease?
Its enzyme UrdA generates imidazole propionate (ImP), which enters the brain, activates mTORC1, triggering α-synuclein aggregation and dopaminergic neuron loss
www.nature.com/articles/s41...
ⓞⓕ Ⓟⓐⓡⓚⓘⓝⓢⓞⓝ 'ⓢ
Nat Comm: 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘮𝘶𝘵𝘢𝘯𝘴 a driver of Parkinson’s disease?
Its enzyme UrdA generates imidazole propionate (ImP), which enters the brain, activates mTORC1, triggering α-synuclein aggregation and dopaminergic neuron loss
www.nature.com/articles/s41...
Reposted by ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
A Communications Medicine publication proposes a comprehensive One Health stewardship framework to address AMR. CARB-X and Global Antibiotic R&D Partnership (GARDP) are recognized as important push incentives supporting antibiotic R&D. #IDSky 🧪
🔗 Read here: bit.ly/3KSyMvh
🔗 Read here: bit.ly/3KSyMvh
October 17, 2025 at 5:07 PM
A Communications Medicine publication proposes a comprehensive One Health stewardship framework to address AMR. CARB-X and Global Antibiotic R&D Partnership (GARDP) are recognized as important push incentives supporting antibiotic R&D. #IDSky 🧪
🔗 Read here: bit.ly/3KSyMvh
🔗 Read here: bit.ly/3KSyMvh