ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
Physician-scientist at UC San Diego, Microbiology, Immunology, Novel Drug and Vaccine Discovery, #IDSky, Mentoring and Supporting STEM Career Development.
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
Enjoy exploring the outdoors, world cultures, sports, comedy, community.
http://nizetlab.ucsd.edu
Pinned
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
@nizet.bsky.social
· Nov 26
by forming a biofilm, streptococci gain resistance to immune or antibiotic clearance
Reposted by ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
I will be giving talks at UC San Diego (Dept Bioengineering) and Sanford Burnham Prebys Institute this coming Friday and the following Tuesday in La Jolla.
I will talk about 3D mapping of solid tumors and new CAR T therapies to resolve them.
Hope to see you there.
I will talk about 3D mapping of solid tumors and new CAR T therapies to resolve them.
Hope to see you there.
February 8, 2026 at 10:36 PM
I will be giving talks at UC San Diego (Dept Bioengineering) and Sanford Burnham Prebys Institute this coming Friday and the following Tuesday in La Jolla.
I will talk about 3D mapping of solid tumors and new CAR T therapies to resolve them.
Hope to see you there.
I will talk about 3D mapping of solid tumors and new CAR T therapies to resolve them.
Hope to see you there.
our neighborhood rodent control officer here in Pacific Highlands Ranch (San Diego)
red-shouldered hawk (Buteo lineatus)
red-shouldered hawk (Buteo lineatus)
February 8, 2026 at 3:29 PM
our neighborhood rodent control officer here in Pacific Highlands Ranch (San Diego)
red-shouldered hawk (Buteo lineatus)
red-shouldered hawk (Buteo lineatus)
A festival of filtered light through this grove of Coast Redwoods (Sequoia sempervirens) in Reinhardt Regional Park the hills above Oakland, CA
February 8, 2026 at 2:06 PM
A festival of filtered light through this grove of Coast Redwoods (Sequoia sempervirens) in Reinhardt Regional Park the hills above Oakland, CA
We deserve dignity in our future leaders
For example, I remember a gracious and empathetic President and First Lady who treated all Americans with respect and vigorously championed innovative research for disease cures and evidence-based clinical care for children and other vulnerable populations
For example, I remember a gracious and empathetic President and First Lady who treated all Americans with respect and vigorously championed innovative research for disease cures and evidence-based clinical care for children and other vulnerable populations
February 7, 2026 at 4:17 PM
We deserve dignity in our future leaders
For example, I remember a gracious and empathetic President and First Lady who treated all Americans with respect and vigorously championed innovative research for disease cures and evidence-based clinical care for children and other vulnerable populations
For example, I remember a gracious and empathetic President and First Lady who treated all Americans with respect and vigorously championed innovative research for disease cures and evidence-based clinical care for children and other vulnerable populations
Visiting NY Academy of Sciences
February 4, 2026 at 6:32 PM
Visiting NY Academy of Sciences
February 1, 2026 at 9:44 PM
The Royal Swedish Academy of Sciences said it was awarding Ramanathan the Crafoord Prize in Geosciences for his groundbreaking work that has “laid the foundation for our understanding of how small particles and gases that accumulate in the atmosphere contribute to climate change.”
Distinguished UC San Diego Climate Scientist Awarded Crafoord Prize
Veerabhadran Ramanathan, a renowned climate scientist at UC San Diego’s Scripps Institution of Oceanography, has been selected as the 2026 recipient of the Crafoord Prize — one of the world’s most pre...
today.ucsd.edu
January 30, 2026 at 3:39 AM
The Royal Swedish Academy of Sciences said it was awarding Ramanathan the Crafoord Prize in Geosciences for his groundbreaking work that has “laid the foundation for our understanding of how small particles and gases that accumulate in the atmosphere contribute to climate change.”
"Bear" (2005) Tim Hawkinson
Eight granite boulders
23.5 feet high
185 tons (370,000 pounds)
UC San Diego Campus
Stuart Collection
Eight granite boulders
23.5 feet high
185 tons (370,000 pounds)
UC San Diego Campus
Stuart Collection
January 28, 2026 at 3:30 PM
"Bear" (2005) Tim Hawkinson
Eight granite boulders
23.5 feet high
185 tons (370,000 pounds)
UC San Diego Campus
Stuart Collection
Eight granite boulders
23.5 feet high
185 tons (370,000 pounds)
UC San Diego Campus
Stuart Collection
Reposted by ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
Yesterday it was cows using tools, today its penguins using satellite imagery.
January 20, 2026 at 6:44 PM
Yesterday it was cows using tools, today its penguins using satellite imagery.
Reposted by ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
We're going to randomise patients in SNAP to: 1) clopidogrel vs no clopidogrel (CLOPIDO SNAP #1) and; 2) aspirin vs clopidogrel for those already on aspirin (CLOPIDO SNAP #2).
January 20, 2026 at 4:38 AM
We're going to randomise patients in SNAP to: 1) clopidogrel vs no clopidogrel (CLOPIDO SNAP #1) and; 2) aspirin vs clopidogrel for those already on aspirin (CLOPIDO SNAP #2).
Pleased to share our brief commentary on how antiplatelet drugs such as ticagrelor (Brilinta) may have an intriguing beneficial action toward effective treatment of Staphylococcus aureus bacteremia and endovascular infection
#drugrepurposing
#drugrepurposing
Bridging specialties: repurposing platelet drugs prescribed by cardiologists to help infectious disease doctors treat Staphylococcus aureus bacteremia
The platelet is the most important cell in the bloodstream in providing endovascular immunity against Staphylococcus aureus bacteremia. Both quantitative and qualitative thrombocytopenia have been ...
www.tandfonline.com
January 20, 2026 at 1:29 AM
Pleased to share our brief commentary on how antiplatelet drugs such as ticagrelor (Brilinta) may have an intriguing beneficial action toward effective treatment of Staphylococcus aureus bacteremia and endovascular infection
#drugrepurposing
#drugrepurposing
a "Bed of Nails" to combat antibiotic-resistant pathogens
"NANOPILLARS" are the novel anti-biofilm strategy
Bioengineering of materials (e.g. catheters) to mimic structures naturally found on the wings of cicadas that mechanically pierce and kill Pseudomonas aeruginosa
"NANOPILLARS" are the novel anti-biofilm strategy
Bioengineering of materials (e.g. catheters) to mimic structures naturally found on the wings of cicadas that mechanically pierce and kill Pseudomonas aeruginosa
Piercing pathogens: A new anti-biofilm strategy
A bacterial cell settles onto a nondescript surface. It is plump, healthy and functioning as it should. Nothing appears amiss.
phys.org
January 19, 2026 at 7:21 PM
a "Bed of Nails" to combat antibiotic-resistant pathogens
"NANOPILLARS" are the novel anti-biofilm strategy
Bioengineering of materials (e.g. catheters) to mimic structures naturally found on the wings of cicadas that mechanically pierce and kill Pseudomonas aeruginosa
"NANOPILLARS" are the novel anti-biofilm strategy
Bioengineering of materials (e.g. catheters) to mimic structures naturally found on the wings of cicadas that mechanically pierce and kill Pseudomonas aeruginosa
This is some crazy stuff—roughly 1.5 miles in 54 degree water and strong currents
Famously, no human has been officially confirmed to have successfully escaped Alcatraz
From the video (link below) looks like the #coyote may have regrets about the adventure
Animals—especially canines—are amazing
Famously, no human has been officially confirmed to have successfully escaped Alcatraz
From the video (link below) looks like the #coyote may have regrets about the adventure
Animals—especially canines—are amazing
San Francisco coyote swims to Alcatraz for first time ever
"This was the first time our park biologists observed anything like this."
www.sfgate.com
January 19, 2026 at 12:44 AM
This is some crazy stuff—roughly 1.5 miles in 54 degree water and strong currents
Famously, no human has been officially confirmed to have successfully escaped Alcatraz
From the video (link below) looks like the #coyote may have regrets about the adventure
Animals—especially canines—are amazing
Famously, no human has been officially confirmed to have successfully escaped Alcatraz
From the video (link below) looks like the #coyote may have regrets about the adventure
Animals—especially canines—are amazing
𝗜𝗠𝗣𝗢𝗥𝗧𝗔𝗡𝗧 𝗧𝗢 𝗞𝗡𝗢𝗪
Comprehensive analysis confirms safety of TYLENOL 💊 in pregnancy
𝘊𝘶𝘳𝘳𝘦𝘯𝘵 𝘦𝘷𝘪𝘥𝘦𝘯𝘤𝘦 𝘥𝘰𝘦𝘴 𝘯𝘰𝘵 𝘪𝘯𝘥𝘪𝘤𝘢𝘵𝘦 𝘢 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭𝘭𝘺 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘪𝘯𝘤𝘳𝘦𝘢𝘴𝘦 𝘪𝘯 𝘵𝘩𝘦 𝘭𝘪𝘬𝘦𝘭𝘪𝘩𝘰𝘰𝘥 𝘰𝘧 𝘢𝘶𝘵𝘪𝘴𝘮 𝘴𝘱𝘦𝘤𝘵𝘳𝘶𝘮 𝘥𝘪𝘴𝘰𝘳𝘥𝘦𝘳, 𝘈𝘋𝘏𝘋, 𝘰𝘳 𝘪𝘯𝘵𝘦𝘭𝘭𝘦𝘤𝘵𝘶𝘢𝘭 𝘥𝘪𝘴𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘪𝘯 𝘤𝘩𝘪𝘭𝘥𝘳𝘦𝘯 𝘰𝘧 𝘱𝘳𝘦𝘨𝘯𝘢𝘯𝘵 𝘪𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭𝘴 𝘸𝘩𝘰 𝘶𝘴𝘦 𝘱𝘢𝘳𝘢𝘤𝘦𝘵𝘢𝘮𝘰𝘭 𝘢𝘴 𝘥𝘪𝘳𝘦𝘤𝘵𝘦𝘥
Comprehensive analysis confirms safety of TYLENOL 💊 in pregnancy
𝘊𝘶𝘳𝘳𝘦𝘯𝘵 𝘦𝘷𝘪𝘥𝘦𝘯𝘤𝘦 𝘥𝘰𝘦𝘴 𝘯𝘰𝘵 𝘪𝘯𝘥𝘪𝘤𝘢𝘵𝘦 𝘢 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭𝘭𝘺 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘪𝘯𝘤𝘳𝘦𝘢𝘴𝘦 𝘪𝘯 𝘵𝘩𝘦 𝘭𝘪𝘬𝘦𝘭𝘪𝘩𝘰𝘰𝘥 𝘰𝘧 𝘢𝘶𝘵𝘪𝘴𝘮 𝘴𝘱𝘦𝘤𝘵𝘳𝘶𝘮 𝘥𝘪𝘴𝘰𝘳𝘥𝘦𝘳, 𝘈𝘋𝘏𝘋, 𝘰𝘳 𝘪𝘯𝘵𝘦𝘭𝘭𝘦𝘤𝘵𝘶𝘢𝘭 𝘥𝘪𝘴𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘪𝘯 𝘤𝘩𝘪𝘭𝘥𝘳𝘦𝘯 𝘰𝘧 𝘱𝘳𝘦𝘨𝘯𝘢𝘯𝘵 𝘪𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭𝘴 𝘸𝘩𝘰 𝘶𝘴𝘦 𝘱𝘢𝘳𝘢𝘤𝘦𝘵𝘢𝘮𝘰𝘭 𝘢𝘴 𝘥𝘪𝘳𝘦𝘤𝘵𝘦𝘥
Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis
Current evidence does not indicate a clinically important increase in the likelihood
of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant
individuals who use paracetam...
www.thelancet.com
January 17, 2026 at 8:03 PM
𝗜𝗠𝗣𝗢𝗥𝗧𝗔𝗡𝗧 𝗧𝗢 𝗞𝗡𝗢𝗪
Comprehensive analysis confirms safety of TYLENOL 💊 in pregnancy
𝘊𝘶𝘳𝘳𝘦𝘯𝘵 𝘦𝘷𝘪𝘥𝘦𝘯𝘤𝘦 𝘥𝘰𝘦𝘴 𝘯𝘰𝘵 𝘪𝘯𝘥𝘪𝘤𝘢𝘵𝘦 𝘢 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭𝘭𝘺 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘪𝘯𝘤𝘳𝘦𝘢𝘴𝘦 𝘪𝘯 𝘵𝘩𝘦 𝘭𝘪𝘬𝘦𝘭𝘪𝘩𝘰𝘰𝘥 𝘰𝘧 𝘢𝘶𝘵𝘪𝘴𝘮 𝘴𝘱𝘦𝘤𝘵𝘳𝘶𝘮 𝘥𝘪𝘴𝘰𝘳𝘥𝘦𝘳, 𝘈𝘋𝘏𝘋, 𝘰𝘳 𝘪𝘯𝘵𝘦𝘭𝘭𝘦𝘤𝘵𝘶𝘢𝘭 𝘥𝘪𝘴𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘪𝘯 𝘤𝘩𝘪𝘭𝘥𝘳𝘦𝘯 𝘰𝘧 𝘱𝘳𝘦𝘨𝘯𝘢𝘯𝘵 𝘪𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭𝘴 𝘸𝘩𝘰 𝘶𝘴𝘦 𝘱𝘢𝘳𝘢𝘤𝘦𝘵𝘢𝘮𝘰𝘭 𝘢𝘴 𝘥𝘪𝘳𝘦𝘤𝘵𝘦𝘥
Comprehensive analysis confirms safety of TYLENOL 💊 in pregnancy
𝘊𝘶𝘳𝘳𝘦𝘯𝘵 𝘦𝘷𝘪𝘥𝘦𝘯𝘤𝘦 𝘥𝘰𝘦𝘴 𝘯𝘰𝘵 𝘪𝘯𝘥𝘪𝘤𝘢𝘵𝘦 𝘢 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭𝘭𝘺 𝘪𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘵 𝘪𝘯𝘤𝘳𝘦𝘢𝘴𝘦 𝘪𝘯 𝘵𝘩𝘦 𝘭𝘪𝘬𝘦𝘭𝘪𝘩𝘰𝘰𝘥 𝘰𝘧 𝘢𝘶𝘵𝘪𝘴𝘮 𝘴𝘱𝘦𝘤𝘵𝘳𝘶𝘮 𝘥𝘪𝘴𝘰𝘳𝘥𝘦𝘳, 𝘈𝘋𝘏𝘋, 𝘰𝘳 𝘪𝘯𝘵𝘦𝘭𝘭𝘦𝘤𝘵𝘶𝘢𝘭 𝘥𝘪𝘴𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘪𝘯 𝘤𝘩𝘪𝘭𝘥𝘳𝘦𝘯 𝘰𝘧 𝘱𝘳𝘦𝘨𝘯𝘢𝘯𝘵 𝘪𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭𝘴 𝘸𝘩𝘰 𝘶𝘴𝘦 𝘱𝘢𝘳𝘢𝘤𝘦𝘵𝘢𝘮𝘰𝘭 𝘢𝘴 𝘥𝘪𝘳𝘦𝘤𝘵𝘦𝘥
Ensuring high quality mentorship and career development opportunities for our junior faculty and postdoctoral fellows are a big focus of our Health Sciences Office of Faculty Affairs (OFA), Altman Clinical and Translational Research Institute (ACTRI), and Faculty Mentor Training Programs (FMTP).
UC San Diego Health Sciences Grant Writing Course Helps Launch Successful Research Careers
According to a new study, 79% of participants in the UC San Diego Health Sciences Grant Writing Course have received grant funding for their research since taking the course, which emphasizes peer rev...
today.ucsd.edu
January 13, 2026 at 8:06 PM
Ensuring high quality mentorship and career development opportunities for our junior faculty and postdoctoral fellows are a big focus of our Health Sciences Office of Faculty Affairs (OFA), Altman Clinical and Translational Research Institute (ACTRI), and Faculty Mentor Training Programs (FMTP).
From first hand clinical experience, meningococcal sepsis and meningitis are indelibly etched in my mind—diseases that can progress rapidly from flu-like symptoms to loss of life or limb—even in previously health children & young adults
Vaccination had reduced rates up to 90% – don't give up now
Vaccination had reduced rates up to 90% – don't give up now
As cases of a rare, deadly infection rise, doctors worry fewer teens will get vaccinated
Under Robert F. Kennedy Jr.’s guidance, the CDC no longer recommends routine vaccination to protect against meningococcal disease.
www.nbcnews.com
January 12, 2026 at 4:16 PM
From first hand clinical experience, meningococcal sepsis and meningitis are indelibly etched in my mind—diseases that can progress rapidly from flu-like symptoms to loss of life or limb—even in previously health children & young adults
Vaccination had reduced rates up to 90% – don't give up now
Vaccination had reduced rates up to 90% – don't give up now
New Year's 2026 Party and this year's Lab T-Shirt
January 11, 2026 at 10:45 PM
New Year's 2026 Party and this year's Lab T-Shirt
The Da Vinci Code
Scientists may have extracted Leonardo da Vinci’s DNA from Renaissance artwork
Researchers collect trace DNA from ‘Holy Child’ drawing and letters written by Italian polymath’s ancestor
www.independent.co.uk
January 9, 2026 at 3:50 AM
The Da Vinci Code
I thought today's bright pre-dawn San Diego moon might bring out the coyotes ...
January 5, 2026 at 5:30 PM
I thought today's bright pre-dawn San Diego moon might bring out the coyotes ...
This paper has everything I could wish for in a scientific insight!
Puppy ➡️ Strep ➡️ Happiness
Dog ownership in adolescents was associated with fewer social problems and altered gut microbiota. Notably, a Streptococcus ASV correlated with sociability in both adolescents and ex-germ-free mice.
Puppy ➡️ Strep ➡️ Happiness
Dog ownership in adolescents was associated with fewer social problems and altered gut microbiota. Notably, a Streptococcus ASV correlated with sociability in both adolescents and ex-germ-free mice.
Dog ownership during adolescence alters the microbiota and improves mental health
Microbiome; Psychology
www.cell.com
January 5, 2026 at 1:01 PM
This paper has everything I could wish for in a scientific insight!
Puppy ➡️ Strep ➡️ Happiness
Dog ownership in adolescents was associated with fewer social problems and altered gut microbiota. Notably, a Streptococcus ASV correlated with sociability in both adolescents and ex-germ-free mice.
Puppy ➡️ Strep ➡️ Happiness
Dog ownership in adolescents was associated with fewer social problems and altered gut microbiota. Notably, a Streptococcus ASV correlated with sociability in both adolescents and ex-germ-free mice.
Clever idea!
Nasal spray using lipid nanoparticles that delivers molecular instructions to flu-infected respiratory cells in a 2-stage process:
(a) an mRNA instructs cells to make Cas13, followed by
(b) a guide RNA directing Cas13 to a specific region of the influenza virus RNA to inactivate it
Nasal spray using lipid nanoparticles that delivers molecular instructions to flu-infected respiratory cells in a 2-stage process:
(a) an mRNA instructs cells to make Cas13, followed by
(b) a guide RNA directing Cas13 to a specific region of the influenza virus RNA to inactivate it
Flu Is Relentless. Crispr Might Be Able to Shut It Down
Innovative research into the gene-editing tool targets influenza’s ability to replicate—stopping it in its tracks.
www.wired.com
January 5, 2026 at 10:44 AM
Clever idea!
Nasal spray using lipid nanoparticles that delivers molecular instructions to flu-infected respiratory cells in a 2-stage process:
(a) an mRNA instructs cells to make Cas13, followed by
(b) a guide RNA directing Cas13 to a specific region of the influenza virus RNA to inactivate it
Nasal spray using lipid nanoparticles that delivers molecular instructions to flu-infected respiratory cells in a 2-stage process:
(a) an mRNA instructs cells to make Cas13, followed by
(b) a guide RNA directing Cas13 to a specific region of the influenza virus RNA to inactivate it
Vaccines are a key aspect of healthy aging.
I'm keeping up to date to protect me, my family, and friends from specific pathogens (RSV, Shingles, Flu, Pneumococcus).
Added benefits of reduced risk of dementia, heart attacks, and stroke, along with longer overall health span are icing on the cake!
I'm keeping up to date to protect me, my family, and friends from specific pathogens (RSV, Shingles, Flu, Pneumococcus).
Added benefits of reduced risk of dementia, heart attacks, and stroke, along with longer overall health span are icing on the cake!
Vaccines Are Helping Older People More Than We Knew
www.nytimes.com
January 4, 2026 at 10:33 AM
Vaccines are a key aspect of healthy aging.
I'm keeping up to date to protect me, my family, and friends from specific pathogens (RSV, Shingles, Flu, Pneumococcus).
Added benefits of reduced risk of dementia, heart attacks, and stroke, along with longer overall health span are icing on the cake!
I'm keeping up to date to protect me, my family, and friends from specific pathogens (RSV, Shingles, Flu, Pneumococcus).
Added benefits of reduced risk of dementia, heart attacks, and stroke, along with longer overall health span are icing on the cake!
ANTALYTICAL THINKING
A 2024 study in PNAS found that ants outperform humans at tests of collective intelligence.
C'mon people, we need to step it up
www.pnas.org/doi/10.1073/...
A 2024 study in PNAS found that ants outperform humans at tests of collective intelligence.
C'mon people, we need to step it up
www.pnas.org/doi/10.1073/...
December 23, 2025 at 4:48 PM
ANTALYTICAL THINKING
A 2024 study in PNAS found that ants outperform humans at tests of collective intelligence.
C'mon people, we need to step it up
www.pnas.org/doi/10.1073/...
A 2024 study in PNAS found that ants outperform humans at tests of collective intelligence.
C'mon people, we need to step it up
www.pnas.org/doi/10.1073/...