CTI-111 binds multiple sepsis-associated human cytokines in the complex environment of ex vivo septic serum—highlighting its potential as a multifaceted sepsis therapy

Ongoing work is expanding CTI-111's utility to additional severe infectious or inflammatory conditions

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Article @ ACS Nano:

Human macrophage membrane-derived drug candidate CTI-111 sequesters soluble microbial toxins, drivers of inflammation, and pro-inflammatory cytokines from multiple sources. Therapeutic administration of CTI-111 reduces inflammation and improves survival in multiple murine sepsis models

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In the United States, sepsis results in the hospitalization of more than one million patients annually and accounts for nearly one in three hospital deaths. Despite decades of efforts to develop immunoregulatory sepsis therapies, no clinically approved treatments exist.

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Millie is a cream colored version of our dog Peanut

Today (NYT): Among the buildings hit hardest, officials said, is Black River Hospital in St. Elizabeth Parish. Floodwaters breached the building and forced the evacuation of about 75 patients "But evacuations are being hindered by blocked roads and power outages"

just from my iPhone while hiking around the neighborhood