Joy Edwards-Hicks
@joyedwardshicks.bsky.social
Immunologist at The University of Edinburgh working on immune cell metabolism and ageing. BBSRC Discovery Fellow. UCU.
Reposted by Joy Edwards-Hicks
Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell
great work by Martin Picard
www.scientificamerican.com/article/why-...
great work by Martin Picard
www.scientificamerican.com/article/why-...
The Hidden Social Lives of Mitochondria
When these energy-giving organelles thrive, so do we
www.scientificamerican.com
May 22, 2025 at 4:41 AM
Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell
great work by Martin Picard
www.scientificamerican.com/article/why-...
great work by Martin Picard
www.scientificamerican.com/article/why-...
Reposted by Joy Edwards-Hicks
Wow, incredibly promising preliminary data on real world use of RSV vaccinations.
RSV vaccinations decreased infant hospitalizations by 43%, may have helped lower infant mortality rates for whole population. www.cdc.gov/mmwr/volumes...
Interim Evaluation of Respiratory Syncytial ...
This report describes RSV-associated hospitalization rates among infants and young children during the 2024–25 respiratory virus season.
www.cdc.gov
May 20, 2025 at 7:24 PM
Wow, incredibly promising preliminary data on real world use of RSV vaccinations.
Reposted by Joy Edwards-Hicks
Reposted by Joy Edwards-Hicks
1/10 Today in @science.org in collaboration with
the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...
the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...
May 15, 2025 at 10:49 PM
1/10 Today in @science.org in collaboration with
the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...
the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...
Reposted by Joy Edwards-Hicks
Some cover art I made for a great paper about the body’s clock and biological aging! #SciArt
Read here our original article showing the biological age prediction by accumulating stochastic variation alone. With @meyer.bsky.social and a wonderful cover art designed by @maayanvisuals.bsky.social www.nature.com/articles/s43...
April 30, 2025 at 7:24 AM
Some cover art I made for a great paper about the body’s clock and biological aging! #SciArt
Reposted by Joy Edwards-Hicks
✊ Dundee Uni backs down from plans to cut 700 jobs after pressure from unions and the community.
Now they must take compulsory redundancies off the table.
Solidarity works.
Now they must take compulsory redundancies off the table.
Solidarity works.
It’s a relief to see Dundee University backtrack on 700 job cuts. We now need the employer to take compulsory redundancies off the table #StopTheCuts @ducuuo.bsky.social
www.ucu.org.uk/article/1399...
www.ucu.org.uk/article/1399...
UCU comment on University of Dundee alternative recovery plan
www.ucu.org.uk
April 30, 2025 at 9:42 AM
✊ Dundee Uni backs down from plans to cut 700 jobs after pressure from unions and the community.
Now they must take compulsory redundancies off the table.
Solidarity works.
Now they must take compulsory redundancies off the table.
Solidarity works.
Reposted by Joy Edwards-Hicks
Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy.
Check out the #News&Views by @adriaenssenslab.bsky.social here.
Check out the #News&Views by @adriaenssenslab.bsky.social here.
April 30, 2025 at 9:47 AM
Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy.
Check out the #News&Views by @adriaenssenslab.bsky.social here.
Check out the #News&Views by @adriaenssenslab.bsky.social here.
Reposted by Joy Edwards-Hicks
The UK government is promoting a “strategic shift” from “treatment to prevention.”
Healthcare alone cannot restrain demand and prevention requires action on wider determinants of health, say
Vageesh Jain and Thomas Beaney www.bmj.com/content/389/...
Healthcare alone cannot restrain demand and prevention requires action on wider determinants of health, say
Vageesh Jain and Thomas Beaney www.bmj.com/content/389/...
April 30, 2025 at 9:56 AM
The UK government is promoting a “strategic shift” from “treatment to prevention.”
Healthcare alone cannot restrain demand and prevention requires action on wider determinants of health, say
Vageesh Jain and Thomas Beaney www.bmj.com/content/389/...
Healthcare alone cannot restrain demand and prevention requires action on wider determinants of health, say
Vageesh Jain and Thomas Beaney www.bmj.com/content/389/...
Reposted by Joy Edwards-Hicks
So depressing...
Well the NIH has cancelled the Women's Health Initiative, the largest study of women in history
It has been running continuously since 1991 and has provided massive key knowledge about diseases in women
Unreal
www.science.org/content/arti...
It has been running continuously since 1991 and has provided massive key knowledge about diseases in women
Unreal
www.science.org/content/arti...
NIH cancels its first and largest study centered on women
The Women’s Health Initiative has produced numerous influential findings
www.science.org
April 23, 2025 at 5:44 PM
So depressing...
Reposted by Joy Edwards-Hicks
Reposted by Joy Edwards-Hicks
#Hiring soon for a research assistant with a BSc in #pharmacology, #physiology or #biochemistry.
Looking for someone young and eager to learn, pre-PhD.
Job advert will go live in a few weeks
#newPI #Sheffield #neuroscience #brainbloodflow #CBF #science
Looking for someone young and eager to learn, pre-PhD.
Job advert will go live in a few weeks
#newPI #Sheffield #neuroscience #brainbloodflow #CBF #science
April 22, 2025 at 9:19 AM
#Hiring soon for a research assistant with a BSc in #pharmacology, #physiology or #biochemistry.
Looking for someone young and eager to learn, pre-PhD.
Job advert will go live in a few weeks
#newPI #Sheffield #neuroscience #brainbloodflow #CBF #science
Looking for someone young and eager to learn, pre-PhD.
Job advert will go live in a few weeks
#newPI #Sheffield #neuroscience #brainbloodflow #CBF #science
Reposted by Joy Edwards-Hicks
I write about marimo, and how to choose the right programming language for your research, today in @nature.com www.nature.com/articles/d41...
Which programming language should I use? A guide for early-career researchers
Computer scientists and bioinformaticians address four key questions to help rookie coders to make the right choice.
www.nature.com
April 22, 2025 at 7:46 PM
I write about marimo, and how to choose the right programming language for your research, today in @nature.com www.nature.com/articles/d41...
Reposted by Joy Edwards-Hicks
Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2 https://www.biorxiv.org/content/10.1101/2025.04.19.649664v1
April 21, 2025 at 3:45 AM
Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2 https://www.biorxiv.org/content/10.1101/2025.04.19.649664v1
Reposted by Joy Edwards-Hicks
179 experts. 28 countries. 1 message:
Long COVID is real, multi-systemic, and devastating. It affects over 400 million people. And we're not prepared.
New global consensus just dropped.
link.springer.com/content/pdf/10…
🧵
Long COVID is real, multi-systemic, and devastating. It affects over 400 million people. And we're not prepared.
New global consensus just dropped.
link.springer.com/content/pdf/10…
🧵
https://link.springer.com/content/pdf/10…
April 21, 2025 at 2:35 AM
179 experts. 28 countries. 1 message:
Long COVID is real, multi-systemic, and devastating. It affects over 400 million people. And we're not prepared.
New global consensus just dropped.
link.springer.com/content/pdf/10…
🧵
Long COVID is real, multi-systemic, and devastating. It affects over 400 million people. And we're not prepared.
New global consensus just dropped.
link.springer.com/content/pdf/10…
🧵
Reposted by Joy Edwards-Hicks
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis
Mitochondria serve as central hubs in cellular metabolism by sensing, integrating, and responding to metabolic demands. This integrative function is a…
www.sciencedirect.com
April 17, 2025 at 9:24 PM
Happy to share our most recent review on mitochondria-organelle metabolic communication with Yatrik Shah and Costas Lyssiotis now online at Molecular Cell!
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals!
www.sciencedirect.com/science/arti...
Reposted by Joy Edwards-Hicks
Reposted by Joy Edwards-Hicks
Cells are swapping their mitochondria. What does this mean for our health?
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Cells are swapping their mitochondria. What does this mean for our health?
Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.
www.nature.com
April 11, 2025 at 6:39 AM
Cells are swapping their mitochondria. What does this mean for our health?
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Joy Edwards-Hicks
It used to be thought that T-cell priming occurred as single phase. Now we know it takes two.
www.science.org/doi/10.1126/...
@science.org
www.science.org/doi/10.1126/...
@science.org
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals
T cell priming is characterized by an initial activation phase that involves stable interactions with dendritic cells (DCs). How activated T cells receive the paracrine signals required for their diff...
www.science.org
April 10, 2025 at 6:30 PM
It used to be thought that T-cell priming occurred as single phase. Now we know it takes two.
www.science.org/doi/10.1126/...
@science.org
www.science.org/doi/10.1126/...
@science.org
Reposted by Joy Edwards-Hicks
Reposted by Joy Edwards-Hicks
Scientists have created the first map of mitochondria throughout the entire brain
https://go.nature.com/4c8CLNM
https://go.nature.com/4c8CLNM
First map of human brain mitochondria is ‘groundbreaking’ achievement
Nature - Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
go.nature.com
March 31, 2025 at 1:51 PM
Scientists have created the first map of mitochondria throughout the entire brain
https://go.nature.com/4c8CLNM
https://go.nature.com/4c8CLNM
Reposted by Joy Edwards-Hicks
Check out this new podcast by my friend @anideshpande.bsky.social! It aims to delve into the history of groundbreaking discoveries in life, science and medicine. The first episode is a fascinating journey through our understanding of diabetes. I looking forward to future episodes!
E1 Diabetes Roots
YouTube video by Discovery Dialogues
www.youtube.com
March 31, 2025 at 3:47 PM
Check out this new podcast by my friend @anideshpande.bsky.social! It aims to delve into the history of groundbreaking discoveries in life, science and medicine. The first episode is a fascinating journey through our understanding of diabetes. I looking forward to future episodes!
Reposted by Joy Edwards-Hicks
Asymmetric phosphoinositide lipid bilayers generated by spontaneous lipid insertion https://www.biorxiv.org/content/10.1101/2025.03.26.645509v1
March 31, 2025 at 2:48 AM
Asymmetric phosphoinositide lipid bilayers generated by spontaneous lipid insertion https://www.biorxiv.org/content/10.1101/2025.03.26.645509v1
Reposted by Joy Edwards-Hicks
Axolotls in your timeline!
March 30, 2025 at 5:25 PM
Axolotls in your timeline!
Reposted by Joy Edwards-Hicks
Neutrophil progenitor cell therapy rescues host defense against Staphylococcus aureus in murine chronic granulomatous disease https://www.biorxiv.org/content/10.1101/2025.03.26.645550v1
March 31, 2025 at 3:16 AM
Neutrophil progenitor cell therapy rescues host defense against Staphylococcus aureus in murine chronic granulomatous disease https://www.biorxiv.org/content/10.1101/2025.03.26.645550v1