Josh Leisring
@joshleisring.bsky.social
Nephrologist / Hypertension Specialist in Columbus, Ohio
#Nephsky
He / him
#Nephsky
He / him
Reposted by Josh Leisring
Ahead of #KidneyWk25, we are recruiting a hypertension fellow to the Stanford Hypertension Center for July 2026. Please come find me at ASN.
med.stanford.edu/nephrology/e...
med.stanford.edu/nephrology/e...
Hypertension Fellowship
med.stanford.edu
November 5, 2025 at 7:57 AM
Ahead of #KidneyWk25, we are recruiting a hypertension fellow to the Stanford Hypertension Center for July 2026. Please come find me at ASN.
med.stanford.edu/nephrology/e...
med.stanford.edu/nephrology/e...
Reposted by Josh Leisring
Samir Parikh gives an update on lupus nephritis. #KidneyWk Looking for rapid reduction of proteinuria? Voclosporin is faster, but belimumab showed similar separation from placebo, it just takes longer due to mechanism of action.
November 5, 2025 at 3:38 PM
Samir Parikh gives an update on lupus nephritis. #KidneyWk Looking for rapid reduction of proteinuria? Voclosporin is faster, but belimumab showed similar separation from placebo, it just takes longer due to mechanism of action.
Reposted by Josh Leisring
BaxHTN phase 3 trial: Aldosterone dysregulation is considered a key driver of hard-to-control hypertension. Research findings on baxdrostat, a highly selective, potent aldosterone synthase inhibitor, in hard-to-control hypertension are summarized in a new Quick Take video. nej.md/3KCsQGJ
October 15, 2025 at 7:02 PM
BaxHTN phase 3 trial: Aldosterone dysregulation is considered a key driver of hard-to-control hypertension. Research findings on baxdrostat, a highly selective, potent aldosterone synthase inhibitor, in hard-to-control hypertension are summarized in a new Quick Take video. nej.md/3KCsQGJ
Reposted by Josh Leisring
Our @ukkidney.org guidelines here in BMC Nephrology. 💯% agree that in-unit BP should ONLY be used for determining safety of individual HD sessions and NOT long-term CV risk modification. But changing practice will be a long haul.
link.springer.com/epdf/10.1186...
link.springer.com/epdf/10.1186...
Management of blood pressure in adults, children and young people on dialysis: UK kidney association clinical practice guideline
link.springer.com
September 30, 2025 at 12:03 PM
Our @ukkidney.org guidelines here in BMC Nephrology. 💯% agree that in-unit BP should ONLY be used for determining safety of individual HD sessions and NOT long-term CV risk modification. But changing practice will be a long haul.
link.springer.com/epdf/10.1186...
link.springer.com/epdf/10.1186...
Reposted by Josh Leisring
Subclinical primary aldosteronism is an under-recognized driver of cardiovascular risk. Could it be a new target for CV prevention? Read our Circulation editorial —>
September 29, 2025 at 7:03 PM
Subclinical primary aldosteronism is an under-recognized driver of cardiovascular risk. Could it be a new target for CV prevention? Read our Circulation editorial —>
Reposted by Josh Leisring
#NephJC is a labor of a passionate volunteer team that believes education should be accessible, no matter where you are from in the world.
Even if editorial team donates unlimited hours of sleep, there are still costs to cover 💸 (👇 blog)
😊 Be kind, help us to #NephItForward
#Medsky #Nephsky
Even if editorial team donates unlimited hours of sleep, there are still costs to cover 💸 (👇 blog)
😊 Be kind, help us to #NephItForward
#Medsky #Nephsky
It's that time of year again 🍂🍂🍂
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
NephJC 2025 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
www.nephjc.com
September 28, 2025 at 4:47 PM
#NephJC is a labor of a passionate volunteer team that believes education should be accessible, no matter where you are from in the world.
Even if editorial team donates unlimited hours of sleep, there are still costs to cover 💸 (👇 blog)
😊 Be kind, help us to #NephItForward
#Medsky #Nephsky
Even if editorial team donates unlimited hours of sleep, there are still costs to cover 💸 (👇 blog)
😊 Be kind, help us to #NephItForward
#Medsky #Nephsky
Reposted by Josh Leisring
We are thrilled to announce that we have generously received funding for a one-year hypertension fellowship, and we are recruiting now for a candidate to start fellowship July 1, 2026 .
med.stanford.edu/hypertension/e…
-Jehan Zahid Bahrainwala
HTN Fellowship Program Director
med.stanford.edu/hypertension/e…
-Jehan Zahid Bahrainwala
HTN Fellowship Program Director
https://med.stanford.edu/hypertension/e…
September 25, 2025 at 8:02 AM
We are thrilled to announce that we have generously received funding for a one-year hypertension fellowship, and we are recruiting now for a candidate to start fellowship July 1, 2026 .
med.stanford.edu/hypertension/e…
-Jehan Zahid Bahrainwala
HTN Fellowship Program Director
med.stanford.edu/hypertension/e…
-Jehan Zahid Bahrainwala
HTN Fellowship Program Director
Reposted by Josh Leisring
It's that time of year again 🍂🍂🍂
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
NephJC 2025 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
www.nephjc.com
September 22, 2025 at 12:47 AM
It's that time of year again 🍂🍂🍂
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
The #NephJC Fall pledge drive.
Plese give if you are able to support our decades long mission of #FOAMed for all. #NephSky #MedSky
www.nephjc.com/news/2025/9/22/nephjc-fall-pledge-drive
Reposted by Josh Leisring
🚨 Survey Alert!
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?
Click here to read the consent form and take the survey:
redcap.link/barriers.to....
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?
Click here to read the consent form and take the survey:
redcap.link/barriers.to....
September 22, 2025 at 4:19 PM
🚨 Survey Alert!
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?
Click here to read the consent form and take the survey:
redcap.link/barriers.to....
Standardized office BP measurements are recommended everywhere, but still underused.
We want to hear from you: what are the barriers to using them as a routine in clinical practice?
Click here to read the consent form and take the survey:
redcap.link/barriers.to....
Reposted by Josh Leisring
My guess is at least 500 #doctors at my #hospital are on H1B visas including at least a few dozen #hospitalists, and if we lose even a handful to other countries our house of cards #healthcare system will fall apart, let alone all 500+
Hmmmm. So, 25% of the US doctors are foreign-trained, and most of them at some point of their career require H1B visa. I don't know how many doctors with active licenses require H1B visa currently, but this is really stupid 👇🏻
Trump to impose new $100,000 fee for H-1B visas in sweeping overhaul: Report - The Economic Times
Donald Trump plans significant H-1B visa changes. A $100,000 fee may be imposed on applications. The administration believes the visa program hurts American workers. Entry under the H-1B system will b...
m.economictimes.com
September 19, 2025 at 11:11 PM
My guess is at least 500 #doctors at my #hospital are on H1B visas including at least a few dozen #hospitalists, and if we lose even a handful to other countries our house of cards #healthcare system will fall apart, let alone all 500+
Reposted by Josh Leisring
Some of my opinions here on @ajkd.bsky.social Blog; ajkdblog.org/2022/01/19/b...
The @ahascience.bsky.social also has a scientific statement here from 2023 www.ahajournals.org/doi/full/10....
#NephJC Catch up
The @ahascience.bsky.social also has a scientific statement here from 2023 www.ahajournals.org/doi/full/10....
#NephJC Catch up
Blood Pressure Measurement in Dialysis: There’s No Place Like Home (Part 1)
This is a 2-part blog post by #NephJC cofounder, hypertension guru, and longtime AJKD contributor Swapnil Hiremath. In Part 1, he outlines the quandaries of blood pressure management in hemodialysi…
ajkdblog.org
September 19, 2025 at 12:33 PM
Some of my opinions here on @ajkd.bsky.social Blog; ajkdblog.org/2022/01/19/b...
The @ahascience.bsky.social also has a scientific statement here from 2023 www.ahajournals.org/doi/full/10....
#NephJC Catch up
The @ahascience.bsky.social also has a scientific statement here from 2023 www.ahajournals.org/doi/full/10....
#NephJC Catch up
Reposting this again - very relevant for #NephJC discussion on the new AHA/ACC guidelines.
To accompany the new ACC/AHA BP guidelines, a practical guide on how to test for Primary Aldosteronism: now recommended for most people with hypertension.
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
September 18, 2025 at 3:36 AM
Reposting this again - very relevant for #NephJC discussion on the new AHA/ACC guidelines.
Reposted by Josh Leisring
❤️Check out the VA for the discussion on the AHA/ACC Hypertension Guidelines 9/16/25 at 9pm EST by @sejalplakhani.bsky.social #NephJC #NephSky #MedSky
www.nephjc.com/news/2025/9/ahaacc-htnguide
www.nephjc.com/news/2025/9/ahaacc-htnguide
The AHA/ACC 2025 Hypertension Guidelines visual abstract — NephJC
New updated guidance on hypertension including screening for secondary causes, use of renal denervation, hypertension and pregnancy, risk assessment, monitoring and treatment. Check out this wonderfu...
www.nephjc.com
September 16, 2025 at 11:47 AM
❤️Check out the VA for the discussion on the AHA/ACC Hypertension Guidelines 9/16/25 at 9pm EST by @sejalplakhani.bsky.social #NephJC #NephSky #MedSky
www.nephjc.com/news/2025/9/ahaacc-htnguide
www.nephjc.com/news/2025/9/ahaacc-htnguide
Reposted by Josh Leisring
To accompany the new ACC/AHA BP guidelines, a practical guide on how to test for Primary Aldosteronism: now recommended for most people with hypertension.
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
September 7, 2025 at 1:04 AM
To accompany the new ACC/AHA BP guidelines, a practical guide on how to test for Primary Aldosteronism: now recommended for most people with hypertension.
www.jacc.org/doi/10.1016/...
www.jacc.org/doi/10.1016/...
Reposted by Josh Leisring
Confirmatory testing (aldosterone suppression testing) for primary aldosteronism: not reliable, or reproducible, for diagnosis or predicting lateralization. Sensitivity at the expense of specificity, and vice-versa. Time to simplify the process
academic.oup.com/ejendo/artic...
academic.oup.com/ejendo/artic...
Discordance and shortcomings of aldosterone suppression tests in primary aldosteronism
AbstractBackground. The saline suppression test (SST) and the captopril challenge test (CCT) have traditionally been used to confirm or exclude primary ald
academic.oup.com
September 7, 2025 at 1:16 AM
Confirmatory testing (aldosterone suppression testing) for primary aldosteronism: not reliable, or reproducible, for diagnosis or predicting lateralization. Sensitivity at the expense of specificity, and vice-versa. Time to simplify the process
academic.oup.com/ejendo/artic...
academic.oup.com/ejendo/artic...
Reposted by Josh Leisring
Excellent summary of the ACHIEVE trial from @drsaivani.bsky.social & @thekidneywhisperer.bsky.social
#NephJC chat tomorrow
www.nephjc.com/news/achieve
#NephJC chat tomorrow
www.nephjc.com/news/achieve
In ESRD is spironolactone an overACHIEVEr? — NephJC
This week, we will discuss the ACHIEVE trial. Will spironolactone achieve CV benefits in ESRD?
www.nephjc.com
September 1, 2025 at 5:36 PM
Excellent summary of the ACHIEVE trial from @drsaivani.bsky.social & @thekidneywhisperer.bsky.social
#NephJC chat tomorrow
www.nephjc.com/news/achieve
#NephJC chat tomorrow
www.nephjc.com/news/achieve
Reposted by Josh Leisring
#WeekendReads from #EditorsChoice
Can you have normal looking adrenal glands with primary aldosteronism?
🔗 academic.oup.com/ajh/article/... 🔓
Can you have normal looking adrenal glands with primary aldosteronism?
🔗 academic.oup.com/ajh/article/... 🔓
Morphologically Normal-Appearing Adrenal Glands as a Prevalent Source of Aldosterone Production in Primary Aldosteronism
AbstractBackground. Normal-appearing adrenal glands on cross-sectional imaging may still be the source of aldosterone production in primary aldosteronism (
academic.oup.com
August 31, 2025 at 12:30 PM
#WeekendReads from #EditorsChoice
Can you have normal looking adrenal glands with primary aldosteronism?
🔗 academic.oup.com/ajh/article/... 🔓
Can you have normal looking adrenal glands with primary aldosteronism?
🔗 academic.oup.com/ajh/article/... 🔓
Reposted by Josh Leisring
The era of ASIs is slowly dawning
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | NEJM
Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension.
In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated
systolic blood pr...
www.nejm.org
August 30, 2025 at 2:39 PM
The era of ASIs is slowly dawning
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
Reposted by Josh Leisring
❓What’s new in BP care?
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
August 28, 2025 at 6:54 PM
❓What’s new in BP care?
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
Reposted by Josh Leisring
The CPC from last @ahascience.bsky.social #HypertensionSessions now published in @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
thanks to @drjmluther.bsky.social and all the education editors for the invite
We hope it makes for an educational read!
www.ahajournals.org/doi/10.1161/...
thanks to @drjmluther.bsky.social and all the education editors for the invite
We hope it makes for an educational read!
August 20, 2025 at 6:09 PM
The CPC from last @ahascience.bsky.social #HypertensionSessions now published in @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
thanks to @drjmluther.bsky.social and all the education editors for the invite
We hope it makes for an educational read!
www.ahajournals.org/doi/10.1161/...
thanks to @drjmluther.bsky.social and all the education editors for the invite
We hope it makes for an educational read!
Reposted by Josh Leisring
More on Hydra-ANCA-zine
Four cases, and review of previous (~ 169) cases reported in the literature
academic.oup.com/ckj/article-... in @ckj-era.bsky.social
#NephSky #Hydralazine
Four cases, and review of previous (~ 169) cases reported in the literature
academic.oup.com/ckj/article-... in @ckj-era.bsky.social
#NephSky #Hydralazine
Hydralazine-induced antineutrophil cytoplasmic antibody-associated glomerulonephritis
Antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) can lead to multi-organ failure and death [1, 2]. As an antihypertensive medica
academic.oup.com
August 18, 2025 at 10:14 AM
More on Hydra-ANCA-zine
Four cases, and review of previous (~ 169) cases reported in the literature
academic.oup.com/ckj/article-... in @ckj-era.bsky.social
#NephSky #Hydralazine
Four cases, and review of previous (~ 169) cases reported in the literature
academic.oup.com/ckj/article-... in @ckj-era.bsky.social
#NephSky #Hydralazine
Commentary on expanded screening for primary aldosteronism in the new HTN guideline.
www.ahajournals.org/doi/10.1161/... 🔓
www.ahajournals.org/doi/10.1161/... 🔓
August 15, 2025 at 7:56 PM
Commentary on expanded screening for primary aldosteronism in the new HTN guideline.
www.ahajournals.org/doi/10.1161/... 🔓
www.ahajournals.org/doi/10.1161/... 🔓
Reposted by Josh Leisring
Nice to see new AHA HTN guidelines emphasizing albuminuria detection!
"[Urine ACR] (a test that assesses kidney health) is now recommended for all patients with high blood pressure. It was recommended as an optional test in the 2017 guideline."
newsroom.heart.org/news/new-hig...
"[Urine ACR] (a test that assesses kidney health) is now recommended for all patients with high blood pressure. It was recommended as an optional test in the 2017 guideline."
newsroom.heart.org/news/new-hig...
New high blood pressure guideline emphasizes prevention, early treatment to reduce CVD risk
Guideline Highlights: Nearly half of all adults in the U.S. have high blood pressure (≥130/80 mm Hg), which is the #1 preventable risk factor for cardiovascular disease, including heart attack, stroke...
newsroom.heart.org
August 14, 2025 at 8:11 PM
Nice to see new AHA HTN guidelines emphasizing albuminuria detection!
"[Urine ACR] (a test that assesses kidney health) is now recommended for all patients with high blood pressure. It was recommended as an optional test in the 2017 guideline."
newsroom.heart.org/news/new-hig...
"[Urine ACR] (a test that assesses kidney health) is now recommended for all patients with high blood pressure. It was recommended as an optional test in the 2017 guideline."
newsroom.heart.org/news/new-hig...
Reposted by Josh Leisring
Some key changes that stood out to me (got the opportunity to help w writing these!):
1) Stronger recs for single pill combos
2) Broader recs for screening for primary aldo (now consider in anyone with stage 2 HTN — i.e., BP >=140/90)
3) Just. Say. No… to cuffless BP devices… and to EtOH
2/
1) Stronger recs for single pill combos
2) Broader recs for screening for primary aldo (now consider in anyone with stage 2 HTN — i.e., BP >=140/90)
3) Just. Say. No… to cuffless BP devices… and to EtOH
2/
No.to
August 14, 2025 at 6:10 PM
Some key changes that stood out to me (got the opportunity to help w writing these!):
1) Stronger recs for single pill combos
2) Broader recs for screening for primary aldo (now consider in anyone with stage 2 HTN — i.e., BP >=140/90)
3) Just. Say. No… to cuffless BP devices… and to EtOH
2/
1) Stronger recs for single pill combos
2) Broader recs for screening for primary aldo (now consider in anyone with stage 2 HTN — i.e., BP >=140/90)
3) Just. Say. No… to cuffless BP devices… and to EtOH
2/