Jakke Neiro
@jakkeneiro.bsky.social
Postdoc, András Simon Lab, Karolinska Institutet @ki.se - DPhil, University of Oxford @biology.ox.ac.uk - Regeneration - Salamander Sorcerer - Worm Wizard - Embryo '24 https://linktr.ee/jakkeneiro
Reposted by Jakke Neiro
Our paper on the role of neurons in Nematostella head regeneration is now out at @currentbiology.bsky.social Big thank you to all collaborators, it was a pleasure!
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone
Via genetic ablation of neurons, Mazloumi Gavgani et al. show that the nervous system
is essential for defining axial polarity during whole-body regeneration in the sea
anemone Nematostella vectensis.
www.cell.com
November 18, 2025 at 10:00 AM
Our paper on the role of neurons in Nematostella head regeneration is now out at @currentbiology.bsky.social Big thank you to all collaborators, it was a pleasure!
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Ectopic head regeneration after nervous system ablation in a sea anemone: Current Biology www.cell.com/current-biol...
Exactly. So that I know when to avoid it.
Brilliant. Just bloody brilliant. 🙄
Weather forecast in Finland: “We may see the sun this week.” Maybe on Thursday.
November 3, 2025 at 8:36 PM
Exactly. So that I know when to avoid it.
Ylen jutusta "Suomalaisilla opiskelijoilla on korkeakouluopintojen alussa keskimäärin paremmat kriittisen ajattelun taidot kuin yhdysvaltalaisten verrokkiyliopistojen opiskelijoilla. Alemman korkeakoulututkinnon loppuvaiheessa merkittävää osaamiseroa ei enää ole."
November 1, 2025 at 6:09 PM
Ylen jutusta "Suomalaisilla opiskelijoilla on korkeakouluopintojen alussa keskimäärin paremmat kriittisen ajattelun taidot kuin yhdysvaltalaisten verrokkiyliopistojen opiskelijoilla. Alemman korkeakoulututkinnon loppuvaiheessa merkittävää osaamiseroa ei enää ole."
Reposted by Jakke Neiro
October 31, 2025 at 11:20 PM
*almost* all
What is the unit of morphological evolution, and how many of these units amount to almost all?
What is the unit of morphological evolution, and how many of these units amount to almost all?
October 31, 2025 at 10:50 PM
*almost* all
What is the unit of morphological evolution, and how many of these units amount to almost all?
What is the unit of morphological evolution, and how many of these units amount to almost all?
Reposted by Jakke Neiro
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
October 31, 2025 at 10:55 AM
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Reposted by Jakke Neiro
Exploring the potential of Schmidtea mediterranea as a model for reproductive toxicity through analysis of sterility caused defective m6A RNA regulation - ScienceDirect
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Exploring the potential of Schmidtea mediterranea as a model for reproductive toxicity through analysis of sterility caused defective m6A RNA regulation
Development of alternative methods for analysis of reproductive toxicity is a challenge that requires the characterization of mechanistic endpoints li…
www.sciencedirect.com
October 28, 2025 at 9:29 PM
Exploring the potential of Schmidtea mediterranea as a model for reproductive toxicity through analysis of sterility caused defective m6A RNA regulation - ScienceDirect
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jakke Neiro
Just going to leave this rather frightening reference about the change in global mammalian biomass from 1860 to now here. 😳🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
October 28, 2025 at 6:53 PM
Just going to leave this rather frightening reference about the change in global mammalian biomass from 1860 to now here. 😳🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Been there, done that.
October 27, 2025 at 10:48 PM
Been there, done that.
Probably sunshine
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey. A Nature Careers article examines what makes earning a doctorate in these countries different. #Academicsky 🧪
Are these the happiest PhD students in the world?
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey — but are these nations really the best places to do a doctorate?
go.nature.com
October 26, 2025 at 12:33 AM
Probably sunshine
Reposted by Jakke Neiro
I love AlphaFold—but please include PAE (Predicted Aligned Error) plots for every “interaction.” Pretty PDBs ≠ proof. If the PAE doesn’t show an interface, it ain’t one. Show the plots. Structural biology's reputation is on the line.
October 24, 2025 at 5:44 PM
I love AlphaFold—but please include PAE (Predicted Aligned Error) plots for every “interaction.” Pretty PDBs ≠ proof. If the PAE doesn’t show an interface, it ain’t one. Show the plots. Structural biology's reputation is on the line.
Reposted by Jakke Neiro
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for the next two years.
William C. Mao and Veronica H. Paulus report.
www.thecrimson.com/article/2025...
William C. Mao and Veronica H. Paulus report.
www.thecrimson.com/article/2025...
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for…
www.thecrimson.com
October 21, 2025 at 1:01 PM
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for the next two years.
William C. Mao and Veronica H. Paulus report.
www.thecrimson.com/article/2025...
William C. Mao and Veronica H. Paulus report.
www.thecrimson.com/article/2025...
Reposted by Jakke Neiro
Reposted by Jakke Neiro
Honouring the life of Sir John Gurdon, who died earlier this week: awarded the Nobel Laureate in Physiology or Medicine for seminal work carried out in Oxford Zoology (now @biology.ox.ac.uk) showing that mature cells could be reprogrammed to become pluripotent.
www.nobelprize.org/prizes/medic...
www.nobelprize.org/prizes/medic...
Nobel Prize in Physiology or Medicine 2012
The Nobel Prize in Physiology or Medicine 2012 was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"
www.nobelprize.org
October 10, 2025 at 12:23 PM
Honouring the life of Sir John Gurdon, who died earlier this week: awarded the Nobel Laureate in Physiology or Medicine for seminal work carried out in Oxford Zoology (now @biology.ox.ac.uk) showing that mature cells could be reprogrammed to become pluripotent.
www.nobelprize.org/prizes/medic...
www.nobelprize.org/prizes/medic...
John Gurdonin muistoa kunnioittaen - kävi myös Suomessa aikoinaan saamassa Yrjö Reenpään mitalin vuonna 1979.
October 7, 2025 at 7:36 PM
John Gurdonin muistoa kunnioittaen - kävi myös Suomessa aikoinaan saamassa Yrjö Reenpään mitalin vuonna 1979.
Reposted by Jakke Neiro
⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology
Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.
www.nature.com
October 6, 2025 at 1:02 PM
⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial
Reposted by Jakke Neiro
🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China
Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq - Nature Genetics
This study introduces single-cell transcription factor (TF) sequencing, a single-cell barcoded and doxycycline-inducible TF overexpression approach that reveals dose-sensitive functional classes of TFs and cellular heterogeneity by mapping TF dose-dependent transcriptomic changes during the reprogramming of mouse embryonic multipotent stromal cells.
www.nature.com
October 6, 2025 at 6:57 AM
🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China
Reposted by Jakke Neiro
New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
Bioelectricity in Morphogenesis
Bioelectricity is likely as old as life itself. From the moment the first proto-cell was enclosed in a lipid bilayer, a membrane potential arose. Thus, one can expect that bioelectrical activities inf...
www.annualreviews.org
October 2, 2025 at 8:14 PM
New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
Reposted by Jakke Neiro
Rachel Carson’s Silent Spring was published OTD in 1962.
“[W]e have now acquired a fateful power to alter and destroy nature. But man is a part of nature, and his war against nature is inevitably a war against himself.”
🌱🐋 # HistSTM 🧪🌎 #philsci #philsky #WomeninSTEM
“[W]e have now acquired a fateful power to alter and destroy nature. But man is a part of nature, and his war against nature is inevitably a war against himself.”
🌱🐋 # HistSTM 🧪🌎 #philsci #philsky #WomeninSTEM
September 26, 2025 at 1:07 PM
Rachel Carson’s Silent Spring was published OTD in 1962.
“[W]e have now acquired a fateful power to alter and destroy nature. But man is a part of nature, and his war against nature is inevitably a war against himself.”
🌱🐋 # HistSTM 🧪🌎 #philsci #philsky #WomeninSTEM
“[W]e have now acquired a fateful power to alter and destroy nature. But man is a part of nature, and his war against nature is inevitably a war against himself.”
🌱🐋 # HistSTM 🧪🌎 #philsci #philsky #WomeninSTEM
The salamander takes it all
The loser's standing small
Beside the victory
That's her destiny
The loser's standing small
Beside the victory
That's her destiny
📸 Every image has a story! This year our 2025 Image Competition winners capture everything from the earliest moments of life to the vast universe within our own tissues.
Explore our digital gallery & follow along as we share more #SciArt this fall:
www.stemcellcenter.lu.se/article/cele...
Explore our digital gallery & follow along as we share more #SciArt this fall:
www.stemcellcenter.lu.se/article/cele...
Celebrating the art in science: Images from the 2025 Image Competition
Lund University. Now in its fourth year, the Lund Stem Cell Center Annual Image Competition has become a valued platform for sharing the visual stories behind our science. It offers a glimpse into the...
www.stemcellcenter.lu.se
September 26, 2025 at 9:42 PM
The salamander takes it all
The loser's standing small
Beside the victory
That's her destiny
The loser's standing small
Beside the victory
That's her destiny
Tvärminne.
The forsaken place where I have spent almost a fortnight dissecting amphipods and their eyes in darkness.
The forsaken place where I have spent almost a fortnight dissecting amphipods and their eyes in darkness.
September 25, 2025 at 7:08 PM
Tvärminne.
The forsaken place where I have spent almost a fortnight dissecting amphipods and their eyes in darkness.
The forsaken place where I have spent almost a fortnight dissecting amphipods and their eyes in darkness.
Reposted by Jakke Neiro
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 24, 2025 at 3:12 PM
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Jakke Neiro
Fab thread about one of the (many) things one walks past in Oxford without much thought...
Time to talk about one of my favourite Oxford buildings, 26-27-28 Cornmarket!!
Popularly known as The Old Pret
Popularly known as The Old Pret
September 22, 2025 at 7:02 PM
Fab thread about one of the (many) things one walks past in Oxford without much thought...
Reposted by Jakke Neiro
The Iberian ribbed newt has the ability to heal its own heart after an injury. The secret might lie in a specific protein also found in humans. Elif Eroglu @ki.se studies salamanders to discover new ways of regenerating our heart cells after a #heartattack.
#research #medicine tinyurl.com/mssmcmc2
#research #medicine tinyurl.com/mssmcmc2
September 1, 2025 at 8:53 AM
The Iberian ribbed newt has the ability to heal its own heart after an injury. The secret might lie in a specific protein also found in humans. Elif Eroglu @ki.se studies salamanders to discover new ways of regenerating our heart cells after a #heartattack.
#research #medicine tinyurl.com/mssmcmc2
#research #medicine tinyurl.com/mssmcmc2
Do apply, especially for the position in Molecular Cell Biology!
Oxford Biology is growing 📢
We’re appointing 3 Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
3 fields. 3 opportunities. One new home for Oxford Biology.
Learn more 👉 bit.ly/41S2Tc7
Apply now 👉 bit.ly/488CNW3
We’re appointing 3 Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
3 fields. 3 opportunities. One new home for Oxford Biology.
Learn more 👉 bit.ly/41S2Tc7
Apply now 👉 bit.ly/488CNW3
September 15, 2025 at 10:22 AM
Do apply, especially for the position in Molecular Cell Biology!