Maile K. Hollinger, PhD
@hollingermk.bsky.social
Immunologist, fungus enthusiast, and Kanaka Maoli. Perpetual question-asker at seminars. Pronouns: they/them/theirs.
Reposted by Maile K. Hollinger, PhD
Commented on this one. We need independent people working for NSF/NIH/USDA/etc
There are only 14,393 comments submitted as of this moment! That's waaaay too few, considering the number of people who are affected by or rely on NIH/NSF funding.
🚨 Action alert: Two days left!!
Help protect NSF/NIH from political interference.
👎 A new rule (Sched. F) would allow for replacing career program officers with political appointees.
➡️ Action: Object here by THIS FRIDAY. Comments can be brief and/or anonymous. Helps future litigation.
Help protect NSF/NIH from political interference.
👎 A new rule (Sched. F) would allow for replacing career program officers with political appointees.
➡️ Action: Object here by THIS FRIDAY. Comments can be brief and/or anonymous. Helps future litigation.
May 22, 2025 at 12:54 AM
Commented on this one. We need independent people working for NSF/NIH/USDA/etc
Congratulations Naomi!!
Rhinovirus as a driver of airway T cell dynamics in children with treatment-refractory recurrent wheeze @jci-insight.bsky.social insight.jci.org/articles/vie...
May 10, 2025 at 4:16 AM
Congratulations Naomi!!
Reposted by Maile K. Hollinger, PhD
This is an absolute disaster. If we don't stop this, they will turn NSF into a pawn of the Trump administration. There will be no research on climate, biodiversity, or anything that isn't eugenics or AI or how to more efficiently destroy the planet for profit.
This cannot be allowed to happen.
This cannot be allowed to happen.
Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions
Changes seen as a response to presidential directives on what research to fund
www.science.org
May 9, 2025 at 3:42 AM
This is an absolute disaster. If we don't stop this, they will turn NSF into a pawn of the Trump administration. There will be no research on climate, biodiversity, or anything that isn't eugenics or AI or how to more efficiently destroy the planet for profit.
This cannot be allowed to happen.
This cannot be allowed to happen.
Does anyone have access to this paper and is willing to share? 🥺UVA doesn't subscribe to NCR!
Tertiary lymphoid organs in human atherosclerotic plaques
www.nature.com/articles/s44...
www.nature.com/articles/s44...
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Single-cell spatial transcriptomics of tertiary lymphoid organ-like structures in human atherosclerotic plaques - Nature Cardiovascular Research
Lai et al. present a spatially resolved atlas of human atherosclerotic plaques, revealing cellular heterogeneity and identifying lymphoid structures and their potential functions and implications.
www.nature.com
April 29, 2025 at 4:46 PM
Does anyone have access to this paper and is willing to share? 🥺UVA doesn't subscribe to NCR!
Reposted by Maile K. Hollinger, PhD
Mucosal stargazing: IgA keeps astrovirus in check @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
April 10, 2025 at 4:04 PM
Mucosal stargazing: IgA keeps astrovirus in check @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Congratulations Kathleen! @annesperling1.bsky.social lab alums represent!!
So happy to see this story come together. Check it out! Kathleen Mills and many collaborators - GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus | Science Immunology www.science.org/doi/10.1126/...
GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus
During mold infection, epithelial-derived GM-CSF licenses neutrophil killing of fungal cells, leading to improved survival.
www.science.org
March 27, 2025 at 2:41 AM
Congratulations Kathleen! @annesperling1.bsky.social lab alums represent!!
Does anyone have the spreadsheet with a list of universities that have implemented hiring freezes? Sincerely, a scared postdoc about to enter the job market
March 27, 2025 at 2:32 AM
Does anyone have the spreadsheet with a list of universities that have implemented hiring freezes? Sincerely, a scared postdoc about to enter the job market
Almost a month late, but our review on Farm Friends--microbes associated with the Farm Effect and prevention of allergic asthma--is now out in Immunological Reviews! Co-authored with Emily Grayson, Dr. Caroline Ferreira, and @annesperling1.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Harnessing the Farm Effect: Microbial Products for the Treatment and Prevention of Asthma Throughout Life
It has long been appreciated that farm exposure early in life protects individuals from allergic asthma. Understanding what component(s) of this exposure is responsible for this protection is crucial...
onlinelibrary.wiley.com
March 27, 2025 at 1:32 AM
Almost a month late, but our review on Farm Friends--microbes associated with the Farm Effect and prevention of allergic asthma--is now out in Immunological Reviews! Co-authored with Emily Grayson, Dr. Caroline Ferreira, and @annesperling1.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Maile K. Hollinger, PhD
Today in #LaborHistory 2/25/1843: Lord Paulet occupied #Hawaii for #Britain. 1898 US annexed it. Hawaiian flag depicted based on Law of Splintered Paddle, protects #civilians in war, after King #Kamehameha showed mercy to a fisherman who'd struck him w/paddle during war. #indigenous #NativeHawaiian
February 25, 2025 at 3:06 PM
Today in #LaborHistory 2/25/1843: Lord Paulet occupied #Hawaii for #Britain. 1898 US annexed it. Hawaiian flag depicted based on Law of Splintered Paddle, protects #civilians in war, after King #Kamehameha showed mercy to a fisherman who'd struck him w/paddle during war. #indigenous #NativeHawaiian
Reposted by Maile K. Hollinger, PhD
I am once again reminding other US citizens that there are American genocides still happening in our own backyard. I'm not saying not to be concerned about Gaza, but we will be more respected globally when we clean up our own house. As it is, we are hypocrites on the world stage.
March 2, 2025 at 5:42 PM
I am once again reminding other US citizens that there are American genocides still happening in our own backyard. I'm not saying not to be concerned about Gaza, but we will be more respected globally when we clean up our own house. As it is, we are hypocrites on the world stage.
Reposted by Maile K. Hollinger, PhD
Did you know there’s a whole spectrum of stuff in between “spend all weekend cleaning your house” and “don’t do anything at all because it’s so overwhelming”?
Wipe down one counter. Put away half a load of laundry. Vacuum one room. You can do a little bit, and it helps! And then you can stop!
Wipe down one counter. Put away half a load of laundry. Vacuum one room. You can do a little bit, and it helps! And then you can stop!
February 22, 2025 at 4:03 PM
Did you know there’s a whole spectrum of stuff in between “spend all weekend cleaning your house” and “don’t do anything at all because it’s so overwhelming”?
Wipe down one counter. Put away half a load of laundry. Vacuum one room. You can do a little bit, and it helps! And then you can stop!
Wipe down one counter. Put away half a load of laundry. Vacuum one room. You can do a little bit, and it helps! And then you can stop!
Congratulations @anukulshenoy.bsky.social!
Lung CD4+ resident memory T cells use airway secretory cells to stimulate/regulate onset of allergic airway neutrophilic disease Cell Reports www.cell.com/cell-reports... @anukulshenoy.bsky.social We identify lung epithelial-CD4+ TRM cell crosstalk as a key rheostat of allergic airway neutrophilia.
Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease
A barrier to understanding neutrophilic asthma and developing effective therapies
is a lack of animal models. Here, Ravi et al. demonstrate that transient and recurrent
inhalation exposure of sensitiz...
www.cell.com
February 19, 2025 at 1:09 AM
Congratulations @anukulshenoy.bsky.social!
Rest in Power Sam. We will bring your torturers to justice.
Please note the police are misgendering Sam Nordquist. One reason violence against trans men is invisible is because it's often treated as violence against women.
Yahoo [Feb 13] -- **TRIGGER WARNING**
NYS Police charged 5 people w/ violently assaulting 24 y/o Black trans man Sam Nordquist for a month before discarding his body in a field, describing it as "beyond depraved."
Rest In Peace, Sam. You are not forgotten.
[by @rikiwilchins.bsky.social]
NYS Police charged 5 people w/ violently assaulting 24 y/o Black trans man Sam Nordquist for a month before discarding his body in a field, describing it as "beyond depraved."
Rest In Peace, Sam. You are not forgotten.
[by @rikiwilchins.bsky.social]
February 16, 2025 at 6:01 PM
Rest in Power Sam. We will bring your torturers to justice.
Reposted by Maile K. Hollinger, PhD
🧪 🎉
Diversity supplements have been reopened! New expiration date May 8 2026
February 16, 2025 at 2:14 AM
🧪 🎉
Reposted by Maile K. Hollinger, PhD
On Valentine’s Day in 1779, Hawaiians killed colonizer Captain Cook upon his 3rd intrusive visit to Hawai’i. His invasive exploration of Australia & our islands in Oceania (Tahiti, Aotearoa, Kanaky, etc) is what triggered British colonization in the Pacific. Thank you Hawaiians 🙏🏽💘🌊
February 14, 2025 at 7:32 PM
On Valentine’s Day in 1779, Hawaiians killed colonizer Captain Cook upon his 3rd intrusive visit to Hawai’i. His invasive exploration of Australia & our islands in Oceania (Tahiti, Aotearoa, Kanaky, etc) is what triggered British colonization in the Pacific. Thank you Hawaiians 🙏🏽💘🌊
Reposted by Maile K. Hollinger, PhD
🧪Thank you to everyone who responded to or shared my request, and to my sources, who all agreed to go on-record at a time when being a scientist (and science journalist) means being a target.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Vaccine sceptic RFK Jr is now a powerful force in US science: what will he do?
Kennedy has expressed support for some fields, but has also declared he’d like a ‘break’ in infectious-disease research.
www.nature.com
February 13, 2025 at 5:46 PM
🧪Thank you to everyone who responded to or shared my request, and to my sources, who all agreed to go on-record at a time when being a scientist (and science journalist) means being a target.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Maile K. Hollinger, PhD
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Direct Economic Contributions
NIH directly supports the economy through investments in research institutions and job formation.
www.nih.gov
February 8, 2025 at 3:08 AM
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Reposted by Maile K. Hollinger, PhD
The loss of AMERICAN science will have ripple effects on jobs and economic growth. At the same time China and other countries are investing heavily in science @schumer.senate.gov @nadler.house.gov
The NIH overhead cut doesn't just hurt universities.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.
It's deadly to the US economy.
The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.
2. While NSF and NIH indeed have a mission to fund specific research innovations via grantmaking, they do a lot more than that.
Their principal role is support a scientific ecosystem in the United States, that includes everything from education and training to infrastructure and communication.
Their principal role is support a scientific ecosystem in the United States, that includes everything from education and training to infrastructure and communication.
February 8, 2025 at 3:18 PM
The loss of AMERICAN science will have ripple effects on jobs and economic growth. At the same time China and other countries are investing heavily in science @schumer.senate.gov @nadler.house.gov
Reposted by Maile K. Hollinger, PhD
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
February 8, 2025 at 3:07 PM
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Reposted by Maile K. Hollinger, PhD
This is the @$%#%Q@ that the people of Hawaii have to deal with every darn day. www.civilbeat.org/2025/01/weal...
Wealthy Second-Home Owners Exploit Local Residents - Honolulu Civil Beat
Decision makers should sharply curtail permits and entitlements for developments.
www.civilbeat.org
January 30, 2025 at 3:58 AM
This is the @$%#%Q@ that the people of Hawaii have to deal with every darn day. www.civilbeat.org/2025/01/weal...
Reposted by Maile K. Hollinger, PhD
If you have students who are trans no you don’t. If you have students of color who may be affected by ICE no you don’t. If anyone asks you gender or racial the makeup of your class you don’t have to tell them.
Protect your class and protect your students by not complying in advance. They trust you.
Protect your class and protect your students by not complying in advance. They trust you.
1. Breaking News: Donald Trump has signed an executive order targeting trans youth and teachers in schools who teach for them.
It goes after "social transition" and threatens arrests.
I will go through line by line, as I have the last 3 nights.
Find the EO here:
www.whitehouse.gov/presidential...
It goes after "social transition" and threatens arrests.
I will go through line by line, as I have the last 3 nights.
Find the EO here:
www.whitehouse.gov/presidential...
Ending Radical Indoctrination in K-12 Schooling – The White House
By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered: Section 1. Purpose and
www.whitehouse.gov
January 30, 2025 at 5:34 PM
If you have students who are trans no you don’t. If you have students of color who may be affected by ICE no you don’t. If anyone asks you gender or racial the makeup of your class you don’t have to tell them.
Protect your class and protect your students by not complying in advance. They trust you.
Protect your class and protect your students by not complying in advance. They trust you.
Reposted by Maile K. Hollinger, PhD
lolsob truth
plus the grant type (investigator-initiated R01 aka what a biomedical Sherlock Holmes needs to keep the lights on) has been devalued by >30 percent since I started my own lab
I get that times are hard all over, but staying alive by defeating disease is both virtuous and valuable
plus the grant type (investigator-initiated R01 aka what a biomedical Sherlock Holmes needs to keep the lights on) has been devalued by >30 percent since I started my own lab
I get that times are hard all over, but staying alive by defeating disease is both virtuous and valuable
The NIH gets >50,000 applications for its primary grant type every year and it’s already so cash strapped that the success rate has only recently crept back over 20 percent. You could triple the NIH budget with money the Pentagon loses in the couch cushions and find plenty of worthy science to fund.
January 25, 2025 at 10:33 AM
lolsob truth
plus the grant type (investigator-initiated R01 aka what a biomedical Sherlock Holmes needs to keep the lights on) has been devalued by >30 percent since I started my own lab
I get that times are hard all over, but staying alive by defeating disease is both virtuous and valuable
plus the grant type (investigator-initiated R01 aka what a biomedical Sherlock Holmes needs to keep the lights on) has been devalued by >30 percent since I started my own lab
I get that times are hard all over, but staying alive by defeating disease is both virtuous and valuable
NIH funding benefits everyone!
January 25, 2025 at 6:36 PM
NIH funding benefits everyone!
This is devastating news! The R01 supplement I received during my PhD training was crucial to supporting me during my PhD.
Research supplements to support URM mentees are set to expire today. I met the person who developed this mechanism, Clifton Poodry, at an NSF meeting last fall; he is so inspiring. This supplement has funded thousands of mentees including myself. Devasted to see it canceled, and with no notice.
January 24, 2025 at 7:27 PM
This is devastating news! The R01 supplement I received during my PhD training was crucial to supporting me during my PhD.